Streptomyces bingchenggensis: SBI_07875
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Entry
SBI_07875 CDS
T01678
Symbol
murF
Name
(GenBank) putative UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sbh
Streptomyces bingchenggensis
Pathway
sbh00300
Lysine biosynthesis
sbh00550
Peptidoglycan biosynthesis
sbh01100
Metabolic pathways
sbh01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sbh00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SBI_07875 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SBI_07875 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SBI_07875 (murF)
Enzymes [BR:
sbh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SBI_07875 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2126
Motif
Other DBs
NCBI-ProteinID:
ADI10995
UniProt:
D7CEX3
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All DBs
Position
9329807..9331249
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AA seq
480 aa
AA seq
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MIALSLAEIIGIVGGQPHDIPDADRKVTGPVVIDSREVRPGGLFAALPGERVDGHDFAAR
AVADGAVAVLAARPVPAAAADAPVPSIVVPDVQAALGALARAVVLRLDATVVALTGSAGK
TSTKDLIAQLLRRHGPTVWTPGSLNNEIGLPLTAMSADETTRHLVLEMGARGKGHIRYLT
DLTPPRLGLVLNVGTAHIGEFGGREAIAEAKGELVEALPAAAEGGVALLNADDPLVRAMA
TRTKARTVLFGEAADADVRAENVRLADGGRPSFTLHTPTGCSEVTMRLYGEHHVSNALAA
AAVAHELGMSVDEIAVALSEAGQLSRWRMEVTERRDGVTVVNDAYNANPESMRAALRALV
AMGTAGQAEGGRTWAVLGPMAELGEESLAEHDAVGRLAVRLNVSKLVAVGGQEAAWLDMG
AKNEGSWGEESVHVSDVRAAVDLLRSELRPGDVVLVKASRSVGLERVAQALLEGEGEVVR
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctgtccctcgccgagatcatcggcatcgtcggcgggcagccgcacgacata
ccggacgcggaccggaaggtcaccggccccgtcgtgatcgactcccgtgaggtgcgcccg
ggcggcctcttcgcggcgctccccggcgagcgcgtggacgggcacgacttcgcggcccgc
gcggtcgcggatggcgcggtggcggtgctggccgcccggcccgtcccggctgccgccgcg
gacgcgcccgtaccgtccatcgtcgtgcccgacgtccaggccgccctgggggcgctggcc
cgcgccgtcgtgctgcgcctggacgccaccgtggtcgcgctcaccggctcggcgggcaag
accagtaccaaggacctgatcgcgcagctgctgcggcggcacggccccaccgtgtggacg
ccgggctcgctcaacaacgagatcggcctgccgctgaccgcgatgagcgccgacgagacg
acccggcacctggtgctggagatgggcgcccggggcaagggccatatccggtacctgacc
gacctcaccccgccccgcctcggcctggtcctcaacgtcggcaccgcccacatcggcgag
ttcggcggccgtgaggcgatcgccgaggccaagggcgagctcgtcgaggccctgcccgca
gccgcggagggcggggtcgcgctgctcaacgccgacgaccccctcgtacgcgccatggcg
acccgcaccaaggcccgtacggtgctgttcggcgaggccgccgacgccgacgtacgtgcc
gagaatgtccggctcgccgacggcggtcggccgtccttcacccttcacacccctaccggg
tgcagcgaagtgaccatgcgcctgtacggtgagcaccacgtgtcgaacgcgcttgccgcg
gccgccgtcgcccatgagttgggcatgtccgtcgacgagatcgccgtggcgctctccgag
gcggggcagctctcccgctggcggatggaggtcaccgagcgccgggacggcgtgacggtc
gtcaacgacgcctacaacgcgaaccccgagtccatgcgagccgcgctccgcgcgctggtc
gcgatgggcacggccggccaggcggaaggggggcgcacgtgggcggtgctgggtccgatg
gccgagctcggcgaggagtcactggccgagcacgacgcggtcgggcggctggccgtcagg
ctcaacgtcagcaagctcgtggcggtcggcggccaggaggccgcatggctcgacatgggc
gccaagaacgagggttcgtggggtgaggagtcggtgcacgtgtccgacgtgcgggcggcg
gtcgatctgttgcgcagcgagctgcgaccgggggacgtcgtgttggtgaaggcatccagg
tcggtggggctggagcgggtcgcgcaggcgttgctcgagggcgagggtgaggtcgtccgc
tga
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