Saccharomyces cerevisiae (budding yeast): YKL140W
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Entry
YKL140W CDS
T00005
Symbol
TGL1, YKL5
Name
(RefSeq) sterol esterase
KO
K01052
lysosomal acid lipase/cholesteryl ester hydrolase [EC:
3.1.1.13
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00100
Steroid biosynthesis
sce04148
Efferocytosis
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09103 Lipid metabolism
00100 Steroid biosynthesis
YKL140W (TGL1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
YKL140W (TGL1)
Enzymes [BR:
sce01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.13 sterol esterase
YKL140W (TGL1)
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Gene cluster
GFIT
Motif
Pfam:
Abhydrolase_1
Abhydro_lipase
Hydrolase_4
Abhydrolase_2
FSH1
Ndr
RseA_C
Motif
Other DBs
NCBI-GeneID:
853717
NCBI-ProteinID:
NP_012782
SGD:
S000001623
UniProt:
P34163
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Position
XI:180779..182425
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AA seq
548 aa
AA seq
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MYFPFLGRLSITDYIIVVLVYIESIISSVLKLIPQPMINLFEWLINFSTSSDDNTIEEKL
RSAPTIHEMCAIFDISVEDHLVRTEDNYILTLHRIPPISKNRFNNKVVYLHHGLLMCSDV
WCCNIERHKNLPFVLHDLGYDVWMGNNRGNKYSTAHLNKPPKSNKFWDFSIDEFAFFDIP
NSIEFILDITKVDKVICIGFSQGSAQMFAAFSLSEKLNRKVSHFIAIAPAMTPKGLHNRI
VDTLAKSSPGFMYLFFGRKIVLPSAVIWQRTLHPTLFNLCIDIANKILFNWKSFNILPRQ
KIASYAKLYSTTSVKSIVHWFQILRSQKFQMFEESDNMLNSLTRPYQIANFPTRTNIKIP
ILLIYGGIDSLVDIDVMKKNLPFNSVFDVKVDNYEHLDLIWGKDADTLVIAKVLRFIEFF
NPGNVSVKTNQLLPSASLVEELPSTTWKTTHPTHGLSYRTHSADRSPLSVQADEADEVHN
ADNSRFLRRVFSTSAIDEDNENEHQDDTEDQIHKEQQRRLSAYLESSKDLRQLDANSSTT
ALDALNKE
NT seq
1647 nt
NT seq
+upstream
nt +downstream
nt
atgtacttcccctttttaggcagattatcgataacagattacattatagtcgtcttggta
tacatagaaagcattatttcatcagtccttaaacttataccacaaccaatgattaacctt
ttcgaatggctaataaatttctcaacgtcctccgatgacaataccatcgaagaaaagtta
aggtcagctccaactatccatgaaatgtgtgcaatttttgatatatctgtcgaggatcat
ttggtaagaactgaagacaattatatcttgacactgcatagaatcccaccgatttctaaa
aacagatttaacaataaagtggtatacttacatcacggtcttttgatgtgttctgatgtt
tggtgttgcaatattgaaagacataaaaacttaccgtttgtattgcatgatttaggttac
gacgtctggatgggaaataatagaggtaataaatattcaactgcccacttgaacaaacca
ccaaaatcgaacaagttttgggatttttctatcgacgaatttgcgttctttgacattcca
aactcaattgaattcatcttagatataacaaaagtggacaaggtcatctgcatcggattc
tctcaaggctctgctcaaatgtttgctgcattttcgttgagtgaaaaattgaatcgaaaa
gtctcccattttatagccatagcacccgctatgactccaaaggggttgcacaacagaatt
gtcgataccttggccaaatcatcgcccggctttatgtatcttttctttggtaggaaaatt
gtgttaccttcagctgtcatttggcaaagaactttacatccaacacttttcaatttgtgt
atcgatatcgcaaacaagatactgttcaattggaagtcgtttaacattctaccgagacaa
aagattgcttcttacgcaaaactttattcaacgaccagtgtaaaatccattgttcactgg
ttccaaatattaagatctcagaaatttcaaatgtttgaagagtctgataacatgctaaat
tccttaactaggccttaccaaattgctaattttcctactagaacaaatatcaagattccc
attcttttaatttatggtggcatagattctttagttgatattgatgtgatgaaaaaaaat
ctacccttcaactccgtctttgatgttaaagttgacaattatgaacacctggatttgatt
tggggcaaagatgccgataccttggtcattgctaaagtcttgaggtttattgaatttttt
aaccctggtaatgtttcagtgaagactaaccagttactaccatcagcaagtctggttgag
gaattaccaagcacgacatggaagacaactcatccaacgcatggtctcagttatagaact
cactcggcagaccgttctccgttgtctgtacaagctgatgaagcggatgaggtccacaat
gctgacaattcaaggttcttaagacgagtgttttctactagtgccatagacgaggacaac
gaaaatgagcaccaggatgatacagaagatcaaatccataaggagcagcaaagacggtta
agtgcctatctggaatcatccaaagatttacgacaactagatgccaactcttcgacaact
gcgctggatgctctaaataaagaatga
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