Saccharopolyspora erythraea: SACE_3196
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Entry
SACE_3196 CDS
T00492
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
sen
Saccharopolyspora erythraea
Pathway
sen00290
Valine, leucine and isoleucine biosynthesis
sen00660
C5-Branched dibasic acid metabolism
sen01100
Metabolic pathways
sen01110
Biosynthesis of secondary metabolites
sen01210
2-Oxocarboxylic acid metabolism
sen01230
Biosynthesis of amino acids
Module
sen_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sen00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SACE_3196 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SACE_3196 (leuB)
Enzymes [BR:
sen01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
SACE_3196 (leuB)
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-ProteinID:
CAM02471
Kitasato:
SACE_3196
Cambridge:
SACE_3196
UniProt:
A4FEJ6
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Position
complement(3531480..3532703)
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AA seq
407 aa
AA seq
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MNAPHALDIAVIPGDGIGPELVRSAVEVLRAAAGRDVELRFTSEDAGADAFRRTGSAMSA
ATLERIRTRYHGVLKGPVGLPGVRHPDGTEAGLLGGVLRGGLDTYANVRPIALLPGVDAP
LRGTAVDYVIVRENTEGLYLSRGRGVGNDRACADQLLMTRHGVERVVVHAFELATRRTGA
PADGVRRVTCVDKSNVLRSFAFFREVFDEVATRYPQVEADHRYADAAGHDLVADPGRFDV
LVMENFLGDILSDRRRSGHVPVGQHRRGRGVLRADPRQCARHRGPGQGEPDLADPRGRDA
AGAPRPPPSGPARPHRRGGGVPHRGDPAGRRITGARHRGRDPRHRRGGSRRLTRPRYGFR
RHSVPPHSPGPGVFRRAEVRGDMISTGRGGWYRCRTRLPRRFRASSR
NT seq
1224 nt
NT seq
+upstream
nt +downstream
nt
ttgaacgcaccgcacgcgctggacatcgcggtgatccccggcgacggcatcggcccggag
ctggtccgctccgccgtcgaggtcctgcgggccgccgccgggcgggacgtggagctgcgg
ttcaccagcgaggacgccggtgcggacgccttccgccgcaccgggtccgcgatgagcgcc
gcgacgctggagcgcatccgcacgcgctaccacggcgtgctcaaggggccggtggggctg
cccggcgtgcgccaccccgacggcaccgaggccgggctgctcggcggcgtcctgcgcggc
gggctcgacacctacgccaacgtgcgcccgatcgcgctcctgcccggcgtcgacgctccg
ctgcgcggcaccgccgtcgactacgtcatcgtgcgggagaacaccgagggcctgtacctg
tcgcgcgggcgcggtgtcggcaacgaccgcgcctgcgccgaccagctcctgatgacccgg
cacggcgtcgagcgcgtggtcgtccacgccttcgagctggccacccggcgcacgggtgcc
ccggccgacggcgtccgccgcgtcacgtgcgtggacaagagcaacgtgttgcgcagcttc
gccttcttccgcgaggtcttcgacgaggtcgccacgaggtacccgcaggtcgaggccgac
caccgctacgccgacgcggccgggcacgacctggtcgccgacccgggccgcttcgacgtg
ctggtgatggagaacttcctcggcgacatcctcagcgaccgtcggcggtctgggcatgtg
cccgtcgggcaacatcggcgcggacgcggcgtacttcgagccgatccacggcagtgcgcc
cggcatcgcgggccaggacagggcgaacccgacctcgcagatcctcgcgggcgcgatgct
gctggagcacctcggccaccaccgtccggcccggcgcgtccgcaccgccgtggcggcggc
gtaccgcaccggggcgatccggctggccggaggatcaccggtgcacggcaccgaggccgc
gacccgcgccatcgtcgaggcggttcacggcgcctgacccgcccgcggtacggcttccgg
cggcacagcgttcctccacacagcccaggacctggggttttccgccgtgccgaagtccgc
ggcgatatgatctccaccggtcgaggagggtggtaccggtgccgaacgaggcttcccagg
cgtttccgagcgagcagccgctga
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