Streptomyces glaucescens: SGLAU_09490
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Entry
SGLAU_09490 CDS
T03327
Symbol
murF
Name
(GenBank) putative UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sgu
Streptomyces glaucescens
Pathway
sgu00300
Lysine biosynthesis
sgu00550
Peptidoglycan biosynthesis
sgu01100
Metabolic pathways
sgu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sgu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SGLAU_09490 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SGLAU_09490 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SGLAU_09490 (murF)
Enzymes [BR:
sgu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SGLAU_09490 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
AIR97908
UniProt:
A0A089X453
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All DBs
Position
complement(2158699..2160105)
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AA seq
468 aa
AA seq
DB search
MIALSLAEIAEVVGGQTHDIPDASVLVTGPVVRDSREAGPGSLFAAFVGERVDGHDFAPQ
VVAAGAVAVLGSRPVGVPAIVVDDVQAALGALARHVVDKLGTTLVALTGSAGKTSTKDLI
AQVLQRKAPTVFTPGSLNNEIGLPLTALSATEETRFLVLEMGARGIGHIRYLTGLTPPKI
GLVLNVGSAHIGEFGGREQIAQAKGELVEALPEDGTAVLNADDPYVRAMAARTKAKVLLF
GEADEADVRAENVRLTDTGQPSFTLHTPSGCSDVTMRLYGEHHVSNALAAAAVAHELGMS
AEEIATALSEAGSLSRWRMEVTERPDGVTVVNDAYNANPESMKAALRALAAMGKGRRTWA
VLGKMAELGDESLAEHDAVGRLAVRLNVSKLVAVGGREAAWLQLGAYNEGSWGEESVHVS
DAQAAVDLLRSELRPGDVVLVKASRSVGLESVAQALLESGAEGEVAAR
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgcagaagtcgtcggcgggcagacgcacgacata
ccggacgcgtcggtcctggtgaccggtccggtcgtccgggactcccgtgaggcggggccc
ggcagcctgttcgccgcgttcgtcggcgagcgcgtcgacggccacgacttcgcgccacag
gtcgtggcggcgggcgcggtcgccgtgctcggctcgcgccccgtcggcgtgcccgcgatc
gtcgtggacgacgtccaggcggcactcggcgccctcgcccgccacgtcgtggacaagctc
ggcacgaccctggtcgcgctcaccggctcggcgggcaagaccagcaccaaggacctcatc
gcgcaggtgctccagcgcaaggcgccgacggtgttcacgccgggctcgctcaacaacgag
atcgggctgcccctcaccgcgctcagcgccaccgaggaaacccggttcctggtcctggag
atgggcgcccgcggcatcggccacatccgctacctgaccgggctgacccccccgaagatc
ggcctcgtgctcaacgtcggctccgcgcacatcggtgagttcggcggccgcgagcagatc
gcccaggccaagggcgagttggtggaggcgctccccgaggacggcaccgcggtgctcaac
gccgacgatccgtacgtacgggccatggccgcccgaacgaaggcgaaggtgctgctcttc
ggcgaggccgacgaagcggacgtacgcgcagagaacgtgcggttgacggacaccgggcag
ccctccttcacccttcacacaccctccgggtgcagcgacgtgaccatgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctgggcatgtcc
gcggaagagatcgccaccgcgctctccgaggcgggctccctctcccgctggcggatggag
gtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcgaaccccgag
tccatgaaggccgctctgcgcgcgctggcggccatgggcaaggggcgtcgtacgtgggcg
gtgctcggcaagatggccgagctcggggacgagtcgctcgccgagcacgacgcggtcgga
cggctcgccgtccggctcaacgtcagcaagctcgtcgcggtcgggggcagggaagccgcc
tggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtgcacgtgtcc
gacgcacaggcggcggtcgacctgttgcgcagcgagttgcgcccgggggacgtcgtgctc
gtgaaggcgtcccgttcggtcgggctcgaaagcgttgcccaggcgctgctcgagtccggt
gccgagggtgaggttgccgcccgatga
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