Streptomyces gardneri: H4W23_14105
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Entry
H4W23_14105 CDS
T07252
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sgx
Streptomyces gardneri
Pathway
sgx00790
Folate biosynthesis
sgx01100
Metabolic pathways
sgx01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sgx00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
H4W23_14105
Enzymes [BR:
sgx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
H4W23_14105
6.3.2.17 tetrahydrofolate synthase
H4W23_14105
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QPK45652
LinkDB
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Position
complement(3125853..3127355)
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AA seq
500 aa
AA seq
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MSEPSDQSDDQFDDIVDAETNRDPDLAVIEAGSRTLRTQGGQPQGDPVPSRPEDPELDKA
LREVETELSTRWGETKLEPSVTRIAALMDVLGDPQRAYPSIHITGTNGKTSTARMIEALL
GAFELRTGRYTSPHVQTITERISLDGAPISAERFVETYQDIKPYVELVDAREEYRLSFFE
VLTGMAYAAFADAPVDVAVVEVGMGGTWDATNVIDASVAVVTPIDLDHTDRLGGTTGEIA
GEKSGIIKQGATVILAQQPVDAAQVLLKKAVEVDATVAREGMEFGIVSREVAVGGQLLTL
RGLGGEYDNVFLPLHGAYQAHNAAVALAAVEAFFGIGAEHARTLDPDTVRRAFAQVASPG
RLEIVRSSPTVILDAAHNPHGARATAEGVSEAFGFSRLIGVVSTSGDKDAKGLLEAFEPI
LAEVVITANSNPRATDVDALAAAAVEVFGEDRVVVEPRLDDAIEAAITLAEEEAEYGGAG
VLVTGSIFTVGDARLLLRRG
NT seq
1503 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagccgagcgaccagagtgacgaccagttcgacgacatcgtcgatgccgagacg
aaccgcgaccccgacctggcggtgatcgaggccggcagccgcaccctgcgcacgcagggc
ggtcagccgcagggcgatcccgtgcctagccgccccgaggacccggagctcgacaaggcg
ctgcgcgaggtcgagaccgagctgtccacccgctggggcgagaccaagctggagccctcg
gtcacccggatcgcggccctgatggacgtgctcggcgacccgcagcgcgcgtacccctcg
atccacatcaccggcaccaacggcaagacgtcgacggcccgcatgatcgaggccctgctc
ggcgccttcgagctgcgcaccgggcggtacacctcgccgcacgtgcagacgatcaccgag
cggatcagcctggacggcgccccgatctccgccgagcggttcgtcgagacgtaccaggac
atcaagccgtacgtggagctcgtcgacgcccgtgaggagtaccgcctctccttcttcgag
gtcctcaccggcatggcgtacgcggccttcgccgacgccccggtcgacgtggccgtcgtc
gaggtcggcatgggcggcacctgggacgcgacgaacgtcatcgacgcctcggtcgccgtc
gtcaccccgatcgacctcgaccacaccgacaggctcggcgggacgaccggcgagatcgcc
ggcgagaagtccgggatcatcaagcagggcgcgaccgtcatcctggcccagcagccggtg
gacgcggcccaggtcctgctgaagaaggccgtcgaggtcgacgccaccgtcgcccgcgag
ggcatggagttcggcatcgtctcccgcgaggtcgcggttggcggccagctcctcaccctg
cgcggcctgggcggcgagtacgacaacgtcttcctgccgctgcacggcgcctaccaggcg
cacaacgcggcggtggcgctcgcggcggtcgaggccttcttcggcatcggcgccgagcac
gccaggaccctggacccggacacggtgcgcagggccttcgcccaggtggcctcgcccggc
cgcctggagatcgtccgctcctccccgacggtgatcctcgacgccgcgcacaatccgcac
ggcgcgcgggccacggcggagggcgtcagcgaggccttcggcttctcgcggctcatcggc
gtggtctccacgagcggggacaaggacgccaagggcctcctcgaagccttcgagccgatc
ctcgcggaggtcgtgatcacggcgaactccaacccgcgggccaccgacgtggatgcgctc
gccgcggccgcggtcgaggtcttcggcgaggaccgggtcgtcgtcgagccgcggctcgac
gacgccatcgaggccgcgatcacccttgcggaggaagaggccgagtacggcggcgcggga
gtcctcgtgaccggttcgatcttcacggtcggcgacgcccggctgctgctgcgaaggggc
tga
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