Sarcophilus harrisii (Tasmanian devil): 100925931
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Entry
100925931 CDS
T02286
Symbol
APC2
Name
(RefSeq) adenomatous polyposis coli protein 2 isoform X1
KO
K02085
adenomatosis polyposis coli protein
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04310
Wnt signaling pathway
shr04390
Hippo signaling pathway
shr04550
Signaling pathways regulating pluripotency of stem cells
shr04810
Regulation of actin cytoskeleton
shr04934
Cushing syndrome
shr05010
Alzheimer disease
shr05022
Pathways of neurodegeneration - multiple diseases
shr05165
Human papillomavirus infection
shr05200
Pathways in cancer
shr05206
MicroRNAs in cancer
shr05210
Colorectal cancer
shr05213
Endometrial cancer
shr05217
Basal cell carcinoma
shr05224
Breast cancer
shr05225
Hepatocellular carcinoma
shr05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
100925931 (APC2)
04390 Hippo signaling pathway
100925931 (APC2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100925931 (APC2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100925931 (APC2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100925931 (APC2)
05206 MicroRNAs in cancer
100925931 (APC2)
09162 Cancer: specific types
05210 Colorectal cancer
100925931 (APC2)
05225 Hepatocellular carcinoma
100925931 (APC2)
05226 Gastric cancer
100925931 (APC2)
05217 Basal cell carcinoma
100925931 (APC2)
05213 Endometrial cancer
100925931 (APC2)
05224 Breast cancer
100925931 (APC2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
100925931 (APC2)
09164 Neurodegenerative disease
05010 Alzheimer disease
100925931 (APC2)
05022 Pathways of neurodegeneration - multiple diseases
100925931 (APC2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100925931 (APC2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
shr01009
]
100925931 (APC2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
shr03036
]
100925931 (APC2)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
shr04812
]
100925931 (APC2)
Protein phosphatases and associated proteins [BR:
shr01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
100925931 (APC2)
Chromosome and associated proteins [BR:
shr03036
]
Eukaryotic type
Centrosome formation proteins
Other centriole associated proteins
100925931 (APC2)
Cytoskeleton proteins [BR:
shr04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EB / APC
100925931 (APC2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
APC_basic
Arm_APC_u3
APC_rep
APC_r
APC_N_CC
Arm
SAMP
Suppressor_APC
Sec7-like_HUS
JIP_LZII
HALZ
Motif
Other DBs
NCBI-GeneID:
100925931
NCBI-ProteinID:
XP_031803919
Ensembl:
ENSSHAG00000013109
LinkDB
All DBs
Position
1:663753071..663821927
Genome browser
AA seq
2451 aa
AA seq
DB search
MGLLWFLSFLHSTFFGDEVLEELKMSGPGPTASYEQLVRQVEALSRENTHLRRELQDNSS
HLSKLENETSDMKEVLKHLQGKLEQEARAMVSSGRTELLEQLKALQMDITNLYNLKFQPP
ALAAEPGSRSRSRSPEGSPLHCAAPAATAQGLPKKREELGELSRATVRLLEELDKERCFL
LAEIEKEEQEKLWYYGQLQSLSQRLDELPQSETFSMQTDLIRQQLEFEAQHIRALMEERF
GTSDEMVQRAQIRASRLEQIEKELAEAQAQTQTRERAQQPQPEHQTLLGIKPTGAEGDGE
PEAPTHPEDGTSQLSNSKVEVVFWLLSMLATRDKEDMARTLLAMSSSQESCVAMRRSGCL
PLLLQILHDADREAGPAEGAKDARMRANAALHNIIFSQPDEGQAKKEMRVLHVLEQIRSY
CETCWDWLRMQGQDGGQGPEGGAGPVPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQA
VAELLQVDYEMHKMTNDPLNLALRRYAGMALTNLTFGDVVNKATLCARRGCMQAIVAQLA
SDSEELHQVVSSILRNLSWRADINSKKVLREVGSMTGLMQCALRATKESTLKSVLSALWN
LSAHSTENKAAICLVDGALGFLVSTLTYKCQSNSLAIIESGGGILRNVSSLIATREDYRQ
VLRDHNCLQTLLQHLRSHSLTIVSNACGTLWNLSARSPRDQELLWDLGAVSMLRNLIHSK
HKMIAMGSAAALRNLLTHRPLKYKDTAAVISPGSCMPSLYVRKQKALEAELDARHLAEAL
DTMEKQSLKGQVAKKPPLRHLDSLVKDYASDSGCFDDEDVPALAPGVEVGNPSVLSMFLN
SSFLQGQALPRMPPPRRGPEAEKEDGSSGRGSMDAKKGVMDGTAAAAEKLATKLSVAVAK
IDKLVEDISALHTSSEDSFSLSSGDHGLDWPSGPGEVREARAQSCSPCRLPEAGRREGVG
RAHPLLRLKAAYTSLSNDSLNSSSTSDGYCPREHMKPSPRASFADYREELQRYQQRPSRL
DLKNVVATQPERREPPAQEPAALQGPEMPDGLHKPAVFPGEWAPKDGEGKLAPDAQVHTI
KLSPSYQHVPLLEGMAKVGAVPFPGTGGSSMARKQAWLPPGTLKGSEGLSKIPEKLVAPA
PPAPAAETLQKYSVEDTPICFSRCSSLSSLSSADHGMDGRSRSEDNDLDSDSSLEILEEP
GPGEGEDDGVEDWRPRGAASLPVAIPAPRGDRGDEGASPSQQEDMTPSSSSENYIQETPL
VMSRCSSVSSLGSFESPSIASSIQSDPCSEMVSGTVSPSELPDSPGQTMPPSRSKTPLPE
RETSQFNLQWENNVKKFMDITDFKERFQLPPDLDSTIYFTVEKPDENFSCASSLSALPLH
EHYVQKDVELKLLPPFPERGGGLHFAGHEKREEPGREERLDGPRGGRPRIETHSEDDLEI
LKECISSAMPSRFRKVKTALVPGLPAGKKGLHVPVYMLVPAHAHPSLAARTPRPSRSPYK
EEDSFTDSAEGTPVNFSSATSLSDETLQYPSKDSQGQRAERREPVSRRVTSSHSTPTKMA
GTYKHRVGGASLPLSNRNAEPSRGSLKNLPSLELTVSRPRSAHSERDSRARGDSSHPSGG
HGDVAFQSFCHTTPTEEAVYCFYENDSDEASEALARKAPTGGRAPKKDHRAGKKETEPKP
KAGPPASMRPRVPTKSQHKLIADETPPCYSLSSSVSSLSDLDLSDRDGGQPPNKGGPLHL
QARKPIHTKPPPPAPGRDSSPSSPSLNSDEDLLQRCIGSAMPKRQRHAARHRKAERKPKQ
GSPKAAGSRERKAEIRRELGEEAASDRASDLDSVEWQAIQDGANSIVTWLHQAAAAATSL
SREPSSECDSILSFVSGLSVGSTLQLTLGREEQKRRGKEAGGEVEKKEQIKTAGESKKGG
EARTLNRRISRGPEKPANAQKPVSNLPAVFRGRTVIYMPTLAKGTPKPRSPPKKAVPKTE
PPAKPLPLNQQRSRSLHRPGKISEMAELTLPKRSATPPARMAKTPSSGSSQTSTPSQPSS
KKSPPSSQTSRPVPPPGGKVGTSSPQAKPVKALLSRQHKTQKSPVRIPFMQKPARKPFPG
KNTPPVPEEQGAGAKAGARLNLVRVPSTRSSGSESDRSGFLRQLTFIKESSNLLLRHRSE
ATAPLSQNSSPRRSRPSVPAVFLCSSRCEELKAAKAGPPPSPRASPGERLPRRTSSESPS
RLPVKKAAPAPEPFKRYSSSPHINVVKRSASPAPTLQQGAETGAGRRRSDGEAQPPPQVG
PGEGRAAPSAATKGTWRRIRDEDIPQILKSTLPPTALPLVGTVQEDGPAPQRKTSDAVVQ
TEDFSTSKTNSSTSPTLENREPPKNAASGPAGGAQAPFIGSDVDGLSSKVAAALAFAHEG
LTAPAGGFPSSRHSSPSRAARVTPFNYIPSPMVVPAASDKAVEKAVSLQGE
NT seq
7356 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtggtttctgtccttcctccattccaccttcttcggggacgaggtactg
gaggaactaaagatgtcgggtccaggcccaacggcttcctatgagcagctggtgaggcag
gtggaggccttgagccgggagaacactcacctgcggagagaactccaggataactccagt
catttgtcaaagctggagaatgagacctctgacatgaaggaggtgctgaagcaccttcag
gggaagttggagcaagaagctcgagcaatggtgtcgtctgggcggactgagttgttggag
caactgaaagccctgcagatggatatcaccaacctgtacaacctcaagtttcagccaccg
gctcttgctgcagaacctggcagccggagtcggagccggagcccggagggcagccccctg
cactgtgctgcccctgcagccacagcccaagggctgcccaagaaaagagaagaattggga
gaattgagcagggccaccgtccgcctgctggaggagctagacaaagaaaggtgtttcctg
ctggctgagattgagaaggaggaacaagagaaactctggtattatgggcagctccaaagc
ttgtcccagaggctggatgagctgcctcagtcagaaacgttttccatgcagacagacctg
atccggcagcagttggagtttgaagctcagcacatccgagcgctgatggaagagcgattc
gggacctcggacgagatggtgcagagagctcagatccgagcctctcgcctggaacagatt
gagaaggagcttgcggaagcccaggctcaaacccagacccgggagcgggcgcagcagcca
cagccagaacaccagaccctcctagggataaagccaacgggagcagagggggatggggag
ccagaagcccccacccacccagaagatgggaccagccaactcagcaacagcaaggtggag
gtggtgttctggttgctgtccatgctggccacgagggacaaggaagacatggcccgcacc
ctgctggccatgtcgagctcccaggagagctgcgtggccatgcgccgctcgggctgcctg
ccgctcctgctgcagatcctccatgacgctgaccgagaggccggccccgccgagggggcc
aaggatgcccggatgcgggccaatgcggccctccacaacatcatcttctcccagcccgac
gagggccaggccaagaaggagatgcgcgtgctgcatgtgctggagcagatccgctcctac
tgtgagacttgctgggactggcttcggatgcagggccaagatggaggccagggccccgag
ggcggtgctgggcccgtacctattgaaccacagatttgccaggccacatgtgcagtaatg
aaactctcttttgatgaggaataccgccgagccatgaatgaacttggcgggctgcaggct
gtagcagagttgctgcaggtggattatgagatgcataagatgaccaatgaccctctgaat
ctggccttacggcgctacgcgggcatggccctcaccaatctcaccttcggtgacgtcgtt
aacaaggccacactgtgtgcccggcggggctgtatgcaggccattgtggcccagttggct
tcagacagtgaagagctccaccaggtggtgtccagcatccttcgaaacttgtcctggagg
gcagatatcaacagcaagaaggtcttacgggaagtgggcagtatgactgggctcatgcag
tgtgcccttcgagccactaaggagtccacactgaagagcgtcctcagtgccctgtggaac
ttgtcagctcacagcacggagaacaaggccgccatatgcttggtggatggagccctgggc
ttcctggtcagcactctcacctacaagtgccagagtaactccctagccatcatcgagagt
ggagggggcatcctccggaatgtgtccagcctcattgccacccgggaggactacaggcag
gtgctgcgggaccacaattgccttcagactctgctccagcacctgaggtcacacagcctg
accatcgtgagtaacgcctgtgggaccctgtggaacctgtcggctcggagtccccgtgac
caggagctgctctgggacctgggagccgtgagcatgctgcggaacctgatccactccaag
cacaagatgattgcgatgggcagcgcggccgccctgcgcaacctgctcacacacaggccc
ctcaagtacaaggacacggcggccgtcatctccccaggctcctgcatgcccagtctctac
gtacgcaagcagaaggcgctggaggccgagctggatgccaggcacctggccgaggctctg
gacacgatggagaagcagagcctgaagggtcaggtggccaagaagccgccgctgcgccac
ctcgacagcctggtcaaggattacgcctcggactccggctgcttcgacgatgaggacgtg
cctgccctggcgcccggggtggaggtgggcaatccctctgtcctctccatgttcctcaac
agttccttcctgcagggccaagccttgccccgcatgccgcccccccgccgcggccccgag
gcagagaaggaggatggcagcagcggcaggggcagcatggatgccaagaagggggtgatg
gacgggacggcggcggcggctgagaaactggctaccaaactgtccgtggcggtggccaag
attgacaagctggtggaggacatctcggccctgcacacctcctccgaggacagctttagc
ctcagctctggggaccatgggctggactggccctcggggcctggggaggtccgggaggcc
cgggcccagtcctgctcaccctgccgactgcctgaggcagggaggagggaaggggtgggg
agggcccacccgctgctccggctgaaggcggcttataccagcctgtccaatgacagcttg
aacagcagcagcaccagcgatggctactgcccccgagagcacatgaagccctccccaagg
gcctcgtttgctgactatcgagaggagcttcagaggtaccagcagcgccccagccgcctg
gacctcaagaacgttgtggccacccagccggaaaggagagagcctccggctcaggagcct
gctgccctgcaggggccagaaatgcctgacgggctacacaagccagcagtattccctggg
gagtgggccccaaaagatggggagggcaagcttgcccccgatgcccaggtgcacaccatc
aagctgtcgccctcctaccagcatgtgcctctgctagagggtatggccaaggttggggct
gttccctttcccggcactggaggtagctccatggcccggaagcaggcctggttgcccccg
ggcaccctgaagggctcagagggtctgagcaagatcccagagaaactggtggctcccgcc
ccccctgctcctgcggcagagaccctacagaagtactcggtggaggatactcccatctgc
ttctcccgttgctcctccctctcttccctctcctctgccgaccatggcatggacgggaga
agccgcagtgaagacaacgacctggacagtgactcgtccctggagatcctcgaggagccg
gggcccggggagggagaggatgacggcgtggaggactggaggccccgaggggccgcctcc
ctgcccgtggccatccccgctccccggggtgaccggggcgatgagggtgcctccccctcc
caacaagaagacatgaccccctccagctcctctgagaattacatccaggagactcccctc
gtcatgagccgctgcagctccgtcagctccctgggcagctttgagagcccctccattgcc
agctccatccagagtgacccctgcagtgagatggtgagtggcaccgtgagccccagtgag
cttcccgacagcccggggcagaccatgccccctagccgcagcaagaccccccttccagag
cgggagaccagccagttcaacctgcagtgggaaaacaacgtcaagaagttcatggacatc
accgacttcaaggagcgcttccagctgcccccggacctcgacagcaccatctacttcaca
gtggagaagcccgacgagaacttctcctgtgcctccagcctcagcgctctgcccctccat
gagcactatgtgcagaaggacgtggagctcaagctcctgccccctttccctgagcgtgga
ggtgggcttcacttcgccggccacgaaaaacgggaggagcccgggcgggaggagcggttg
gatgggccccgggggggccggccccgcatagagacccactctgaggacgacctggagatc
ctgaaggaatgtatcagctcagcgatgccctcccgcttccgaaaggtcaagacagccctg
gtgccgggcttgcctgcagggaagaagggcctacatgtgcccgtctacatgttggtgccc
gcacatgcccatcccagcttagcggccaggaccccccggccttcccgcagcccgtataaa
gaggaggattccttcacagactcggctgaaggcacgccagtcaacttctccagcgccacc
tcactcagtgacgagactctccagtatccatccaaggacagccaggggcagcgggctgag
aggagggagcccgtctctcggcgggtcacctccagccattctactccaaccaagatggca
ggtacctacaagcatagggtgggaggggcgagcctccctctctcaaacaggaatgccgaa
cctagccgaggctctctcaagaacctgcccagcctagaactgactgtcagccggcccagg
agtgcccactctgagagggacagccgtgccaggggagacagctcccatccaagtggaggg
cacggggatgttgccttccagtcattctgtcatactacacccactgaagaggcggtttac
tgcttctatgagaatgattcagatgaagcttctgaggccctggcccggaaggcacccacg
ggaggccgggctccaaagaaggaccatcgggcgggcaagaaagaaacagaacccaagccc
aaagcagggcccccagcttccatgcggccccgggtgcccaccaagtcccagcacaaactg
attgcagatgagacaccaccctgctactccttaagctcttccgtaagctcactcagtgac
ctggacctttcggatagggacggtgggcagccacccaacaaagggggcccgctccacctg
caggcccgcaagcccatccacactaagccccccccaccggctccgggtcgggacagttct
cccagctcaccgagcctcaactcggacgaagatctgctccaaaggtgcattggttccgcc
atgcccaaaagacaacgccatgcagcccggcaccgtaaggctgagcgcaagcccaagcaa
gggagccccaaggcagctggcagcagggagcgcaaggctgagatacgtagggagctgggc
gaggaggcggcctccgaccgagcctccgacctggacagtgtggagtggcaggctattcaa
gatggcgccaattccatcgtgacgtggctgcaccaggcggcagcggcagcaacctccttg
tccagggagccctcgtctgagtgtgattccatcctctcctttgtgtccgggctgtcagta
gggtccaccctgcagcttaccctgggaagggaggaacagaagcgcagagggaaggaggct
ggaggagaggtggaaaagaaagagcaaatcaagactgctggtgaaagcaagaaaggaggg
gaggcccggaccctcaaccgccggatatcccggggcccagaaaagccagccaatgcccag
aaacccgtgtccaatctgcccgctgtgttccggggccggacagtcatctacatgcccacc
ctggccaaggggacccccaagccgcgttctcccccaaagaaggctgtgcccaagaccgag
cctcctgccaaacccctccctctcaatcaacagagatcccggagcctccaccggccaggg
aaaatctcagagatggcagagctgacactgcccaagagaagtgccaccccacctgctcgg
atggccaagaccccctcctcaggctcttcccaaacctccaccccttcccagccatcatcc
aagaagtcgcccccctcttcccagacgagcaggccggtccccccacctgggggtaaagtg
ggcaccagcagccctcaggccaagccggtgaaggctctgctctccagacagcacaaaact
caaaaatctccagtacggatcccgttcatgcagaagccggccaggaagccgttcccgggg
aagaacacgcctcctgtcccggaggagcagggggcgggagcaaaggccggggccaggctc
aatctggtcagagtgccctccacccggtccagcggcagcgagtccgaccgttccggcttc
ctgaggcagctgaccttcatcaaggagtcttccaacctcctcctgcggcaccgctccgag
gccaccgcccccctgtcccagaacagctcccctcgccgcagtcggcccagtgtccccgcc
gtcttcctttgctcttctcgttgtgaggagctcaaagcggccaaagccgggcccccgccc
agccccagagcgtcaccaggggagcgcctgccccgccggaccagctcagagagcccctcc
cgcttgcccgtcaagaaagcggctcccgcccctgagcccttcaagcgctattcctcctcc
ccccacatcaacgtggtcaagaggtcggccagcccagcccctacccttcagcaaggggcc
gagactggggctgggcggaggcggagtgatggcgaggcccagccccctccccaggtaggg
ccgggggagggccgcgccgctccatcggcggccaccaagggcacatggcggaggattcgg
gatgaagacatcccccagatcctgaagagcacgctcccccccactgccctgcctctggtc
ggcacagtccaggaggacggcccggctccccagaggaagaccagcgacgctgtggttcag
accgaagacttctcaacttctaaaaccaactctagcacctctcccactctggagaaccgg
gagccccccaagaacgcggcgagcggcccggcaggcggcgcgcaggcccccttcattggc
agcgatgtggacgggctgagctccaaggtggctgccgccctcgcctttgcccacgagggg
ctgacggccccggccgggggcttcccctccagccgccacagctcccccagccgagccgcc
cgagttacccccttcaattacatccccagccccatggtggtgccagccgcgagcgacaaa
gctgtggagaaagctgtcagcctgcagggtgaatag
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integrated database retrieval system
