Streptomyces avermitilis: SAVERM_5601
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Entry
SAVERM_5601 CDS
T00126
Symbol
leuA2
Name
(GenBank) putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sma
Streptomyces avermitilis
Pathway
sma00290
Valine, leucine and isoleucine biosynthesis
sma00620
Pyruvate metabolism
sma01100
Metabolic pathways
sma01110
Biosynthesis of secondary metabolites
sma01210
2-Oxocarboxylic acid metabolism
sma01230
Biosynthesis of amino acids
Module
sma_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sma00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SAVERM_5601 (leuA2)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SAVERM_5601 (leuA2)
Enzymes [BR:
sma01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SAVERM_5601 (leuA2)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
BAC73313
NITE:
SAV5601
UniProt:
Q82BV3
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All DBs
Position
6774328..6776049
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AA seq
573 aa
AA seq
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MANRQQPTSMPIHKYRPYEQVDIADRTWPDNRVTVAPRWLSTDLRDGNQALIDPMSPARK
REMFDLLVKMGYKEIEVGFPASGQTDFDFVRSIIEDETAIPDDVTISVLTQAREDLIERT
VESLVGAKRATVHLYNATAPVFRRVVFRGSKDQIKQIAVDGTRLVVEYAEKLLDERTTFG
YQYSPEIFTDTELDFALEVCEAVMDVWQPGPDREIILNLPATVERSTPSTHADRFEWMSR
NLSRREYVCLSVHPHNDRGTAVAAAELALMAGADRIEGCLFGQGERTGNVDLVTLGMNLF
SQGVDPQIDFSNIDEVRRTAEYCNQMEVHARHPYVGDLVYTSFSGSHQDAIKKGFDAMEA
DAAAKGVTVDDIEWAVPYLPIDPKDVGRSYEAVIRVNSQSGKGGIAYVLKNDHKLDLPRR
MQIEFSKIIQTKTDAEGGEVTPKDIWAVFQDEYLPNPRNPWGRIQVKTGQTTTDKDGVDT
LTVEASVDGVDTVLTGSGNGPISAFFDALQSVGIDVRLLDYTEHTMSEGASAQAASYIEC
AIDGQVLWGIGIDANTTRASLKAVVSAVNRAAR
NT seq
1722 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaccgccagcagcccacgtccatgccgatccacaagtaccgcccgtacgagcag
gtcgacatcgccgaccgcacgtggccggacaaccgggtcaccgtcgctccgcgctggctc
tccaccgacctgcgcgacggcaaccaggccctgatcgaccccatgtcgcccgcccgcaag
cgcgagatgttcgacctgctggtgaagatgggctacaaggagatcgaggtcggtttcccc
gcctccgggcagacggacttcgacttcgtgcggtcgatcatcgaggacgagaccgcgatt
cccgacgacgtcacgatctccgtactgacccaggcccgcgaggacctgatcgagcggacc
gtggagtccctggtcggcgccaagcgcgccaccgtgcacctgtacaacgcgacggccccc
gtcttccggcgggtcgtcttccgcggctccaaggaccagatcaagcagatcgccgtcgac
ggcacccggctggtcgtggagtacgcggagaagctgctggacgagcgcaccacgttcggc
taccagtacagccccgagatcttcaccgacaccgagctggacttcgccctggaggtctgc
gaggccgtcatggacgtctggcagcccggaccggaccgcgagatcatcctcaacctgcct
gccaccgtcgagcgctcgacgccgtcgacgcacgcggaccgcttcgagtggatgagccgc
aacctgtcccgccgcgagtacgtctgcctgtccgtacacccgcacaacgaccgcggtacg
gcggtggcggcggccgagctggccctgatggccggcgccgaccgcatcgagggctgtctg
ttcgggcagggcgagcgcaccggcaacgtcgacctggtcaccctgggcatgaacctgttc
tcgcagggtgtcgacccgcagatcgacttctcgaacatcgacgaggtccgccgcaccgcc
gagtactgcaaccagatggaggtccacgcccgccacccgtacgtcggcgacctcgtctac
acctccttctccggctcccaccaggacgccatcaagaagggcttcgacgcgatggaggcc
gacgcggccgccaagggcgtcacggtcgacgacatcgaatgggccgtcccgtatctgccg
atcgaccccaaggacgtcggccgctcctacgaggccgtcatccgcgtcaactcgcagtcc
ggcaagggcggcatcgcgtacgtcctgaagaacgaccacaagctggacctgccgcgccgg
atgcagatcgagttctcgaagatcatccagacgaaaacggacgccgagggcggcgaggtc
acgccgaaggacatctgggcggtcttccaggacgagtacctgccgaacccgcggaacccg
tggggccgtatccaggtcaagaccggccagaccacgacggacaaggacggcgtggacacg
ctgacggtcgaggcctcggtcgacggcgtcgacaccgtcctgaccggcagcggcaacggt
ccgatctccgcgttcttcgacgcgctgcagtccgtcggcatcgacgtacgtctgctcgac
tacaccgagcacacgatgagcgagggcgcctccgcgcaggccgcctcctacatcgaatgc
gcgatcgacgggcaggtcctgtgggggatcggcatcgacgcgaatacgacacgcgcgtcg
ctgaaggccgtcgtctccgcggtcaaccgcgccgcccgctga
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