Streptococcus pyogenes MGAS6180 (serotype M28): M28_Spy0797
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Entry
M28_Spy0797 CDS
T00263
Symbol
folC.1
Name
(GenBank) folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
spb
Streptococcus pyogenes MGAS6180 (serotype M28)
Pathway
spb00790
Folate biosynthesis
spb01100
Metabolic pathways
spb01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
spb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
M28_Spy0797 (folC.1)
Enzymes [BR:
spb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
M28_Spy0797 (folC.1)
6.3.2.17 tetrahydrofolate synthase
M28_Spy0797 (folC.1)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AAX71910
UniProt:
Q48TQ0
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Position
817619..818896
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AA seq
425 aa
AA seq
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MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHIVGTNGKGSTVNHLQHI
FTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAANRIRPLTERLVQETDFGEVTE
FEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAMVVVCPSIGLDHQAILGETYA
DIAAQKAGVLEGGETLVFAVENPSAREVFLTKAEQVGASIWEWQEQFQMAENASGYRFTS
PLGVISDIHIAMPGHHQVSNAALAIMTCLTLKDRYPRLTSDHIREGLANSLWLGRTELLA
PNLMIDGAHNNESVAALVAVLKNNYNDKKLHILFGAIDTKPIADMLVALEQIGDLQVTGF
HYPNAYPLEKYPERFGRVADFKDFLALRKHAKADDFFVITGSLYFISEIRQYWKKHIEKN
VLLTH
NT seq
1278 nt
NT seq
+upstream
nt +downstream
nt
atgacttatgaagagactctagaatggattcatgatcacttagttttcggcatcaagcca
ggcttaaaacgtatgctttgggttcttggacagttaggaaatccccaaaaaaatgtcaag
ggagtgcatatcgttggaactaacggaaaaggttccacggtcaatcatttacaacacatc
tttacgacagctggttatgaagtggggacctttacctctccttatattatggatttcaaa
gaacgtattagcataaatggtcgaatgatttcagaaaaagatttggttattgctgctaat
cgtattcgtcctttgacagagcgtctagttcaagagactgattttggagaggtaactgaa
tttgaagtgattactttgatcatgttcctctattttggagacatgcatcctgtagatatt
gctattattgaagcaggccttggcggtctttatgattcgaccaatgtttttcaagcaatg
gttgtggtctgtccctcaattggtttagatcaccaagctattttgggagagacttacgct
gatattgccgcccaaaaagctggtgttttagaagggggcgagacccttgtttttgccgtt
gaaaacccgtcagctcgagaggtttttttaacaaaagctgagcaggttggtgcttcaatc
tgggaatggcaagagcagtttcaaatggctgagaacgcatctggctatcgttttactagt
cctttaggagttatttcagatattcacatcgctatgccaggacaccaccaagtgtctaat
gcagctttagctattatgacttgcttaaccttgaaagaccgctatcctaggctaacttca
gatcatataagggaaggtctggcaaatagtttgtggctaggccgtaccgaattattagca
ccaaatctaatgattgatggggctcataacaatgaaagcgttgctgctttggtagccgtc
ttaaaaaataactacaatgataaaaagcttcatattttgtttggtgcgatcgacaccaag
cctattgcggatatgttggttgctcttgagcaaataggtgacttgcaggttactggcttt
cattaccctaacgcctatccattggaaaaatacccagaacgttttggtagggttgctgat
ttcaaagatttcttggccctgcgtaagcatgccaaagcagatgactttttcgtgattaca
gggtcgctatattttatttcagaaattagacagtattggaaaaaacatattgaaaaaaac
gttcttttaacccattaa
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