Streptococcus pyogenes MGAS10750 (serotype M4): MGAS10750_Spy0025
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Entry
MGAS10750_Spy0025 CDS
T00356
Symbol
purM
Name
(GenBank) Phosphoribosylformylglycinamidine cyclo-ligase
KO
K01933
phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.3.1
]
Organism
spi
Streptococcus pyogenes MGAS10750 (serotype M4)
Pathway
spi00230
Purine metabolism
spi01100
Metabolic pathways
spi01110
Biosynthesis of secondary metabolites
Module
spi_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MGAS10750_Spy0025 (purM)
Enzymes [BR:
spi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
MGAS10750_Spy0025 (purM)
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GFIT
Motif
Pfam:
AIRS_C
AIRS
Motif
Other DBs
NCBI-ProteinID:
ABF36975
UniProt:
Q1J936
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Position
42174..43196
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AA seq
340 aa
AA seq
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MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGVLGGFGGMFDLSKTGVKEPVLV
SGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPLYFLDYVATGKNNPVKLEE
VVSGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAVGVAEKSQIIDGSKVKEGDIL
LGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKQLKDVLLEPTRIYVKAALPLIKEEL
VNGIGHITGGGFIENIPRMFADDLAAEIDEDKVPVLPIFKALEKYGDIKHEEMFEIFNMG
VGLMLAVSPENVNRVKELLDEPVYEIGRIIKKADDSVVIK
NT seq
1023 nt
NT seq
+upstream
nt +downstream
nt
atgtctgaaaaaaatgcttatgcaaaatctggtgttgatgttgaagctggttatgaagtg
gttgaaagaataaaaaaacacgttgctcgtacagaacgtgcgggagttatgggagttcta
ggtggctttggtgggatgtttgacttgagtaaaacaggagttaaagagcctgtcttggtt
tcagggactgacggtgtcggaacaaaacttatgcttgctatcaagtacgacaagcacgac
acaatcggtcaagactgtgttgccatgtgtgtcaacgatattattgcagcaggtgctgag
cccctttacttccttgactacgtagcgacaggaaaaaataacccagtcaaacttgaagaa
gttgtttctggcgttgcagaaggttgtgttcaagcaggagcagcactcattggaggtgag
accgctgaaatgcctgggatgtatggcgaagatgattatgaccttgctggctttgctgtt
ggtgtggctgaaaaatctcaaatcatcgacggttcaaaagtaaaagaaggcgatattctt
ttgggacttgcttcaagtggtatccattcaaacggttattctttggtacgtcgtgtcttt
gctgactatactggtaaagagctgcttccagagcttgaaggcaaacaacttaaggatgtc
ctccttgagccaactcgtatctatgttaaagcagctctgccattaatcaaggaagaacta
gtcaacggtatcggccacatcacgggtggtggctttatcgagaatattcctcgtatgttt
gcggatgatttggctgcggaaatcgatgaggacaaggtgccagtgcttccgattttcaag
gcgcttgaaaaatatggtgacatcaagcacgaagaaatgtttgaaatcttcaatatgggt
gtcggtcttatgctagctgttagtcctgaaaatgttaaccgcgtcaaagagctcttggat
gaaccagtttatgaaatcggtcgtatcatcaagaaagcagacgatagtgtggtgattaaa
taa
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