Candidate division SR1 bacterium Aalborg_AAW-1: XF24_00411
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Entry
XF24_00411 CDS
T04487
Name
(GenBank) putative bifunctional UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase/UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
srg
Candidate division SR1 bacterium Aalborg_AAW-1
Pathway
srg00300
Lysine biosynthesis
srg00550
Peptidoglycan biosynthesis
srg01100
Metabolic pathways
srg01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
srg00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
XF24_00411
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
XF24_00411
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
XF24_00411
Enzymes [BR:
srg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
XF24_00411
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AKH32750
UniProt:
A0A288GUA9
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Position
425725..427110
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AA seq
461 aa
AA seq
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MKLKNFLLFKYYQLLGRLAHRYLAKRKPLIIGINGSVGKTSCRMIIDDVLQANLGDQLII
YTSPKNFNGELGMSLSIFKIEEWTPSVSGMISVLKTIISQFKSSASKPYDILILEYGIDR
PREMEFLCSICKPHISILTKLDAVHSLQFGTAEDIANEELKLQKNTLLKCYINNNDPHGM
NLISSLQTKVAIYNTQHNTILEKGIIGATDYTIYHNDHSEPSLTAPICSQSTLHVGGMTM
DFATDCIGQIHHDYVALAYDITETIRKQYNLAPITMKTALSLHLQAGRMSIFEGIHDSII
IDSTYNSSPLSVRKVIEESLMVKNKLFSDRPTLYILGEMRELGESETQHHLELADYLLSK
LHPNDQVLLLGQAMTHTYNKILGNKKQEIGTISHYLDRHDVATKAQEIIETKKQEIGTKF
FIIAKGSQNTIFLEEVVKSLLAHSEDASKLTRQGSRRENKK
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
atgaaacttaaaaacttcctcctcttcaaatattatcaactcctcggacgactcgctcat
cgctatcttgcgaaacgaaaaccacttatcattggtatcaatgggagtgttggaaaaacc
tcatgtaggatgataattgatgatgtgcttcaagcaaatctctgagatcaactcattatc
tacaccagtccaaaaaactttaatggtgaactcggaatgtctctcagtattttcaagatc
gaagaatggacgccatccgtgtcaggtatgatatctgttttaaagaccatcattagccag
tttaaatcctctgccagcaaaccttatgatatccttattttagaatacggtatcgatcgt
ccgagagaaatggaatttttgtgtagtatttgtaaaccacatattagtatcttgacgaag
ctcgatgctgttcatagtctccaatttggtactgcagaagatattgccaatgaagagtta
aaattacaaaaaaacactctcctcaagtgctacatcaacaataatgatcctcacgggatg
aatctaatctcttctttgcagacaaaggtagcaatctataacactcaacacaacacaata
ctagaaaaaggaatcatctgagcgacagattatacgatctatcataatgatcacagcgaa
ccatcactcactgctccgatttgttctcagtctactcttcatgttggtggtatgaccatg
gattttgctactgattgtattggtcagattcatcatgattatgtagcattagcctatgat
atcactgagacgataagaaaacagtacaatctcgcaccgatcacgatgaagactgctctt
tcactccatctccaagctggtaggatgtcgatattcgaagggatacatgacagcatcatc
atcgatagtacctacaatagttctcccctcagcgtgagaaaagtaatcgaagaatcattg
atggtaaaaaacaagttattttctgacagaccgacactgtatattcttggagaaatgaga
gaattaggagagagtgaaacccaacaccatctcgaacttgctgattatctactgagtaaa
ctccacccaaacgatcaagtactactcttgtgacaagcgatgacccacacgtataataaa
atcctaggaaataaaaaacaggaaataggaactatctctcactatctcgatcgacatgat
gtcgcaacgaaagcacaagaaatcatagaaaccaagaagcaagaaataggaactaaattc
tttatcatagccaaaggcagccaaaatacgatctttctcgaagaagtagtgaaatcactc
ctagctcatagcgaagatgcgagtaaactcacgagacaaggatcacgacgagaaaataaa
aaataa
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