Sus scrofa (pig): 100518251 Help Entry 100518251         CDS       T01009                                  Gene name KRAS Definition (RefSeq) GTPase KRas isoform X2   KO K07827   GTPase KRas Organism ssc  Sus scrofa (pig) Pathway ssc01521   EGFR tyrosine kinase inhibitor resistance ssc01522   Endocrine resistance ssc04010   MAPK signaling pathway ssc04012   ErbB signaling pathway ssc04014   Ras signaling pathway ssc04015   Rap1 signaling pathway ssc04062   Chemokine signaling pathway ssc04068   FoxO signaling pathway ssc04071   Sphingolipid signaling pathway ssc04072   Phospholipase D signaling pathway ssc04137   Mitophagy - animal ssc04140   Autophagy - animal ssc04150   mTOR signaling pathway ssc04151   PI3K-Akt signaling pathway ssc04210   Apoptosis ssc04211   Longevity regulating pathway ssc04213   Longevity regulating pathway - multiple species ssc04218   Cellular senescence ssc04360   Axon guidance ssc04370   VEGF signaling pathway ssc04371   Apelin signaling pathway ssc04540   Gap junction ssc04550   Signaling pathways regulating pluripotency of stem cells ssc04625   C-type lectin receptor signaling pathway ssc04650   Natural killer cell mediated cytotoxicity ssc04660   T cell receptor signaling pathway ssc04662   B cell receptor signaling pathway ssc04664   Fc epsilon RI signaling pathway ssc04714   Thermogenesis ssc04720   Long-term potentiation ssc04722   Neurotrophin signaling pathway ssc04725   Cholinergic synapse ssc04726   Serotonergic synapse ssc04730   Long-term depression ssc04810   Regulation of actin cytoskeleton ssc04910   Insulin signaling pathway ssc04912   GnRH signaling pathway ssc04914   Progesterone-mediated oocyte maturation ssc04915   Estrogen signaling pathway ssc04916   Melanogenesis ssc04917   Prolactin signaling pathway ssc04919   Thyroid hormone signaling pathway ssc04921   Oxytocin signaling pathway ssc04926   Relaxin signaling pathway ssc04929   GnRH secretion ssc04933   AGE-RAGE signaling pathway in diabetic complications ssc04935   Growth hormone synthesis, secretion and action ssc04960   Aldosterone-regulated sodium reabsorption ssc05010   Alzheimer disease ssc05022   Pathways of neurodegeneration - multiple diseases ssc05034   Alcoholism ssc05160   Hepatitis C ssc05161   Hepatitis B ssc05163   Human cytomegalovirus infection ssc05165   Human papillomavirus infection ssc05166   Human T-cell leukemia virus 1 infection ssc05167   Kaposi sarcoma-associated herpesvirus infection ssc05170   Human immunodeficiency virus 1 infection ssc05200   Pathways in cancer ssc05203   Viral carcinogenesis ssc05205   Proteoglycans in cancer ssc05206   MicroRNAs in cancer ssc05210   Colorectal cancer ssc05211   Renal cell carcinoma ssc05212   Pancreatic cancer ssc05213   Endometrial cancer ssc05214   Glioma ssc05215   Prostate cancer ssc05216   Thyroid cancer ssc05218   Melanoma ssc05219   Bladder cancer ssc05220   Chronic myeloid leukemia ssc05221   Acute myeloid leukemia ssc05223   Non-small cell lung cancer ssc05224   Breast cancer ssc05225   Hepatocellular carcinoma ssc05226   Gastric cancer ssc05230   Central carbon metabolism in cancer ssc05231   Choline metabolism in cancer ssc05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:ssc00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100518251 (KRAS)    04012 ErbB signaling pathway     100518251 (KRAS)    04014 Ras signaling pathway     100518251 (KRAS)    04015 Rap1 signaling pathway     100518251 (KRAS)    04370 VEGF signaling pathway     100518251 (KRAS)    04371 Apelin signaling pathway     100518251 (KRAS)    04068 FoxO signaling pathway     100518251 (KRAS)    04072 Phospholipase D signaling pathway     100518251 (KRAS)    04071 Sphingolipid signaling pathway     100518251 (KRAS)    04151 PI3K-Akt signaling pathway     100518251 (KRAS)    04150 mTOR signaling pathway     100518251 (KRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100518251 (KRAS)    04137 Mitophagy - animal     100518251 (KRAS)   09143 Cell growth and death    04210 Apoptosis     100518251 (KRAS)    04218 Cellular senescence     100518251 (KRAS)   09144 Cellular community - eukaryotes    04540 Gap junction     100518251 (KRAS)    04550 Signaling pathways regulating pluripotency of stem cells     100518251 (KRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100518251 (KRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     100518251 (KRAS)    04650 Natural killer cell mediated cytotoxicity     100518251 (KRAS)    04660 T cell receptor signaling pathway     100518251 (KRAS)    04662 B cell receptor signaling pathway     100518251 (KRAS)    04664 Fc epsilon RI signaling pathway     100518251 (KRAS)    04062 Chemokine signaling pathway     100518251 (KRAS)   09152 Endocrine system    04910 Insulin signaling pathway     100518251 (KRAS)    04929 GnRH secretion     100518251 (KRAS)    04912 GnRH signaling pathway     100518251 (KRAS)    04915 Estrogen signaling pathway     100518251 (KRAS)    04914 Progesterone-mediated oocyte maturation     100518251 (KRAS)    04917 Prolactin signaling pathway     100518251 (KRAS)    04921 Oxytocin signaling pathway     100518251 (KRAS)    04926 Relaxin signaling pathway     100518251 (KRAS)    04935 Growth hormone synthesis, secretion and action     100518251 (KRAS)    04919 Thyroid hormone signaling pathway     100518251 (KRAS)    04916 Melanogenesis     100518251 (KRAS)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100518251 (KRAS)   09156 Nervous system    04725 Cholinergic synapse     100518251 (KRAS)    04726 Serotonergic synapse     100518251 (KRAS)    04720 Long-term potentiation     100518251 (KRAS)    04730 Long-term depression     100518251 (KRAS)    04722 Neurotrophin signaling pathway     100518251 (KRAS)   09158 Development and regeneration    04360 Axon guidance     100518251 (KRAS)   09149 Aging    04211 Longevity regulating pathway     100518251 (KRAS)    04213 Longevity regulating pathway - multiple species     100518251 (KRAS)   09159 Environmental adaptation    04714 Thermogenesis     100518251 (KRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100518251 (KRAS)    05206 MicroRNAs in cancer     100518251 (KRAS)    05205 Proteoglycans in cancer     100518251 (KRAS)    05203 Viral carcinogenesis     100518251 (KRAS)    05230 Central carbon metabolism in cancer     100518251 (KRAS)    05231 Choline metabolism in cancer     100518251 (KRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100518251 (KRAS)   09162 Cancer: specific types    05210 Colorectal cancer     100518251 (KRAS)    05212 Pancreatic cancer     100518251 (KRAS)    05225 Hepatocellular carcinoma     100518251 (KRAS)    05226 Gastric cancer     100518251 (KRAS)    05214 Glioma     100518251 (KRAS)    05216 Thyroid cancer     100518251 (KRAS)    05221 Acute myeloid leukemia     100518251 (KRAS)    05220 Chronic myeloid leukemia     100518251 (KRAS)    05218 Melanoma     100518251 (KRAS)    05211 Renal cell carcinoma     100518251 (KRAS)    05219 Bladder cancer     100518251 (KRAS)    05215 Prostate cancer     100518251 (KRAS)    05213 Endometrial cancer     100518251 (KRAS)    05224 Breast cancer     100518251 (KRAS)    05223 Non-small cell lung cancer     100518251 (KRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     100518251 (KRAS)    05022 Pathways of neurodegeneration - multiple diseases     100518251 (KRAS)   09165 Substance dependence    05034 Alcoholism     100518251 (KRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     100518251 (KRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100518251 (KRAS)    05170 Human immunodeficiency virus 1 infection     100518251 (KRAS)    05161 Hepatitis B     100518251 (KRAS)    05160 Hepatitis C     100518251 (KRAS)    05163 Human cytomegalovirus infection     100518251 (KRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     100518251 (KRAS)    05165 Human papillomavirus infection     100518251 (KRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100518251 (KRAS)    01522 Endocrine resistance     100518251 (KRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ssc04131]     100518251 (KRAS)   09183 Protein families: signaling and cellular processes    04031 GTP-binding proteins [BR:ssc04031]     100518251 (KRAS) Membrane trafficking [BR:ssc04131]  Endocytosis   Macropinocytosis    Ras GTPases     100518251 (KRAS) GTP-binding proteins [BR:ssc04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     100518251 (KRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 MeaB FeoB_N G-alpha ATP_bind_1 Septin NPR1_interact AAA_25 Motif Other DBs NCBI-GeneID:  100518251 NCBI-ProteinID:  XP_003126475 Ensembl:  ENSSSCG00000026969 UniProt:  A0A287B854 A0A4X1VID5 LinkDB All DBs Position 5 AA seq 188 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKK SKTKCIIM NT seq 567 nt NT seq  +upstreamnt  +downstreamnt atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgaca atacagctaattcagaatcactttgtggatgaatatgatcctacgatagaggattcctac aggaaacaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt caagaggagtacagtgcaatgagggaccagtacatgaggactggggagggctttctttgt gtatttgccataaataatactaagtcatttgaagatattcaccattatagagaacaaata aaaagagttaaagactctgaagatgtacctatggtcctagtaggaaataaatgtgatttg ccttctagaacagtagacacaaaacaggctcaggacttagcaagaagttatggaattcct tttattgaaacatcagcaaagacaagacagggtgttgacgatgccttctatacattagtt cgagaaattcgaaaacataaagaaaagatgagcaaagatggtaaaaagaagaaaaagaag tcaaagacaaagtgtataattatgtaa

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