KEGG   Sus scrofa (pig): 100518251
Entry
100518251         CDS       T01009                                 
Symbol
KRAS
Name
(RefSeq) GTPase KRas isoform X2
  KO
K07827  GTPase KRas
Organism
ssc  Sus scrofa (pig)
Pathway
ssc01521  EGFR tyrosine kinase inhibitor resistance
ssc01522  Endocrine resistance
ssc04010  MAPK signaling pathway
ssc04012  ErbB signaling pathway
ssc04014  Ras signaling pathway
ssc04015  Rap1 signaling pathway
ssc04062  Chemokine signaling pathway
ssc04068  FoxO signaling pathway
ssc04071  Sphingolipid signaling pathway
ssc04072  Phospholipase D signaling pathway
ssc04137  Mitophagy - animal
ssc04140  Autophagy - animal
ssc04150  mTOR signaling pathway
ssc04151  PI3K-Akt signaling pathway
ssc04210  Apoptosis
ssc04211  Longevity regulating pathway
ssc04213  Longevity regulating pathway - multiple species
ssc04218  Cellular senescence
ssc04360  Axon guidance
ssc04370  VEGF signaling pathway
ssc04371  Apelin signaling pathway
ssc04540  Gap junction
ssc04550  Signaling pathways regulating pluripotency of stem cells
ssc04625  C-type lectin receptor signaling pathway
ssc04650  Natural killer cell mediated cytotoxicity
ssc04660  T cell receptor signaling pathway
ssc04662  B cell receptor signaling pathway
ssc04664  Fc epsilon RI signaling pathway
ssc04714  Thermogenesis
ssc04720  Long-term potentiation
ssc04722  Neurotrophin signaling pathway
ssc04725  Cholinergic synapse
ssc04726  Serotonergic synapse
ssc04730  Long-term depression
ssc04810  Regulation of actin cytoskeleton
ssc04910  Insulin signaling pathway
ssc04912  GnRH signaling pathway
ssc04914  Progesterone-mediated oocyte maturation
ssc04915  Estrogen signaling pathway
ssc04916  Melanogenesis
ssc04917  Prolactin signaling pathway
ssc04919  Thyroid hormone signaling pathway
ssc04921  Oxytocin signaling pathway
ssc04926  Relaxin signaling pathway
ssc04929  GnRH secretion
ssc04933  AGE-RAGE signaling pathway in diabetic complications
ssc04935  Growth hormone synthesis, secretion and action
ssc04960  Aldosterone-regulated sodium reabsorption
ssc05010  Alzheimer disease
ssc05022  Pathways of neurodegeneration - multiple diseases
ssc05034  Alcoholism
ssc05160  Hepatitis C
ssc05161  Hepatitis B
ssc05163  Human cytomegalovirus infection
ssc05165  Human papillomavirus infection
ssc05166  Human T-cell leukemia virus 1 infection
ssc05167  Kaposi sarcoma-associated herpesvirus infection
ssc05170  Human immunodeficiency virus 1 infection
ssc05200  Pathways in cancer
ssc05203  Viral carcinogenesis
ssc05205  Proteoglycans in cancer
ssc05206  MicroRNAs in cancer
ssc05207  Chemical carcinogenesis - receptor activation
ssc05208  Chemical carcinogenesis - reactive oxygen species
ssc05210  Colorectal cancer
ssc05211  Renal cell carcinoma
ssc05212  Pancreatic cancer
ssc05213  Endometrial cancer
ssc05214  Glioma
ssc05215  Prostate cancer
ssc05216  Thyroid cancer
ssc05218  Melanoma
ssc05219  Bladder cancer
ssc05220  Chronic myeloid leukemia
ssc05221  Acute myeloid leukemia
ssc05223  Non-small cell lung cancer
ssc05224  Breast cancer
ssc05225  Hepatocellular carcinoma
ssc05226  Gastric cancer
ssc05230  Central carbon metabolism in cancer
ssc05231  Choline metabolism in cancer
ssc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ssc05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100518251 (KRAS)
   04012 ErbB signaling pathway
    100518251 (KRAS)
   04014 Ras signaling pathway
    100518251 (KRAS)
   04015 Rap1 signaling pathway
    100518251 (KRAS)
   04370 VEGF signaling pathway
    100518251 (KRAS)
   04371 Apelin signaling pathway
    100518251 (KRAS)
   04068 FoxO signaling pathway
    100518251 (KRAS)
   04072 Phospholipase D signaling pathway
    100518251 (KRAS)
   04071 Sphingolipid signaling pathway
    100518251 (KRAS)
   04151 PI3K-Akt signaling pathway
    100518251 (KRAS)
   04150 mTOR signaling pathway
    100518251 (KRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100518251 (KRAS)
   04137 Mitophagy - animal
    100518251 (KRAS)
  09143 Cell growth and death
   04210 Apoptosis
    100518251 (KRAS)
   04218 Cellular senescence
    100518251 (KRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100518251 (KRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    100518251 (KRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100518251 (KRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100518251 (KRAS)
   04650 Natural killer cell mediated cytotoxicity
    100518251 (KRAS)
   04660 T cell receptor signaling pathway
    100518251 (KRAS)
   04662 B cell receptor signaling pathway
    100518251 (KRAS)
   04664 Fc epsilon RI signaling pathway
    100518251 (KRAS)
   04062 Chemokine signaling pathway
    100518251 (KRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100518251 (KRAS)
   04929 GnRH secretion
    100518251 (KRAS)
   04912 GnRH signaling pathway
    100518251 (KRAS)
   04915 Estrogen signaling pathway
    100518251 (KRAS)
   04914 Progesterone-mediated oocyte maturation
    100518251 (KRAS)
   04917 Prolactin signaling pathway
    100518251 (KRAS)
   04921 Oxytocin signaling pathway
    100518251 (KRAS)
   04926 Relaxin signaling pathway
    100518251 (KRAS)
   04935 Growth hormone synthesis, secretion and action
    100518251 (KRAS)
   04919 Thyroid hormone signaling pathway
    100518251 (KRAS)
   04916 Melanogenesis
    100518251 (KRAS)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100518251 (KRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    100518251 (KRAS)
   04726 Serotonergic synapse
    100518251 (KRAS)
   04720 Long-term potentiation
    100518251 (KRAS)
   04730 Long-term depression
    100518251 (KRAS)
   04722 Neurotrophin signaling pathway
    100518251 (KRAS)
  09158 Development and regeneration
   04360 Axon guidance
    100518251 (KRAS)
  09149 Aging
   04211 Longevity regulating pathway
    100518251 (KRAS)
   04213 Longevity regulating pathway - multiple species
    100518251 (KRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    100518251 (KRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100518251 (KRAS)
   05206 MicroRNAs in cancer
    100518251 (KRAS)
   05205 Proteoglycans in cancer
    100518251 (KRAS)
   05207 Chemical carcinogenesis - receptor activation
    100518251 (KRAS)
   05208 Chemical carcinogenesis - reactive oxygen species
    100518251 (KRAS)
   05203 Viral carcinogenesis
    100518251 (KRAS)
   05230 Central carbon metabolism in cancer
    100518251 (KRAS)
   05231 Choline metabolism in cancer
    100518251 (KRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100518251 (KRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100518251 (KRAS)
   05212 Pancreatic cancer
    100518251 (KRAS)
   05225 Hepatocellular carcinoma
    100518251 (KRAS)
   05226 Gastric cancer
    100518251 (KRAS)
   05214 Glioma
    100518251 (KRAS)
   05216 Thyroid cancer
    100518251 (KRAS)
   05221 Acute myeloid leukemia
    100518251 (KRAS)
   05220 Chronic myeloid leukemia
    100518251 (KRAS)
   05218 Melanoma
    100518251 (KRAS)
   05211 Renal cell carcinoma
    100518251 (KRAS)
   05219 Bladder cancer
    100518251 (KRAS)
   05215 Prostate cancer
    100518251 (KRAS)
   05213 Endometrial cancer
    100518251 (KRAS)
   05224 Breast cancer
    100518251 (KRAS)
   05223 Non-small cell lung cancer
    100518251 (KRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100518251 (KRAS)
   05170 Human immunodeficiency virus 1 infection
    100518251 (KRAS)
   05161 Hepatitis B
    100518251 (KRAS)
   05160 Hepatitis C
    100518251 (KRAS)
   05163 Human cytomegalovirus infection
    100518251 (KRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100518251 (KRAS)
   05165 Human papillomavirus infection
    100518251 (KRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100518251 (KRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    100518251 (KRAS)
  09165 Substance dependence
   05034 Alcoholism
    100518251 (KRAS)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100518251 (KRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100518251 (KRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100518251 (KRAS)
   01522 Endocrine resistance
    100518251 (KRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ssc04131]
    100518251 (KRAS)
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:ssc04031]
    100518251 (KRAS)
Membrane trafficking [BR:ssc04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    100518251 (KRAS)
GTP-binding proteins [BR:ssc04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    100518251 (KRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N MeaB ATP_bind_1 Septin G1_gp67_C TPR_Trm732 NPR1_interact
Other DBs
NCBI-GeneID: 100518251
NCBI-ProteinID: XP_003126475
Ensembl: ENSSSCG00000026969
UniProt: A0A4X1VID5 A0A8D0XAY1
LinkDB
Position
5:48508774..48546260
AA seq 188 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKK
SKTKCIIM
NT seq 567 nt   +upstreamnt  +downstreamnt
atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgaca
atacagctaattcagaatcactttgtggatgaatatgatcctacgatagaggattcctac
aggaaacaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt
caagaggagtacagtgcaatgagggaccagtacatgaggactggggagggctttctttgt
gtatttgccataaataatactaagtcatttgaagatattcaccattatagagaacaaata
aaaagagttaaagactctgaagatgtacctatggtcctagtaggaaataaatgtgatttg
ccttctagaacagtagacacaaaacaggctcaggacttagcaagaagttatggaattcct
tttattgaaacatcagcaaagacaagacagggtgttgacgatgccttctatacattagtt
cgagaaattcgaaaacataaagaaaagatgagcaaagatggtaaaaagaagaaaaagaag
tcaaagacaaagtgtataattatgtaa

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