Trichechus manatus latirostris (Florida manatee): 101355206
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Entry
101355206 CDS
T05135
Name
(RefSeq) serine-protein kinase ATM isoform X1
KO
K04728
serine-protein kinase ATM [EC:
2.7.11.1
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu01524
Platinum drug resistance
tmu03440
Homologous recombination
tmu04064
NF-kappa B signaling pathway
tmu04068
FoxO signaling pathway
tmu04110
Cell cycle
tmu04115
p53 signaling pathway
tmu04210
Apoptosis
tmu04218
Cellular senescence
tmu05165
Human papillomavirus infection
tmu05166
Human T-cell leukemia virus 1 infection
tmu05170
Human immunodeficiency virus 1 infection
tmu05202
Transcriptional misregulation in cancer
tmu05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
101355206
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
101355206
04068 FoxO signaling pathway
101355206
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
101355206
04210 Apoptosis
101355206
04115 p53 signaling pathway
101355206
04218 Cellular senescence
101355206
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
101355206
05206 MicroRNAs in cancer
101355206
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101355206
05170 Human immunodeficiency virus 1 infection
101355206
05165 Human papillomavirus infection
101355206
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101355206
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tmu01001
]
101355206
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
tmu03032
]
101355206
03036 Chromosome and associated proteins [BR:
tmu03036
]
101355206
03400 DNA repair and recombination proteins [BR:
tmu03400
]
101355206
Enzymes [BR:
tmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101355206
Protein kinases [BR:
tmu01001
]
Serine/threonine kinases: Other
PIKK family [OT]
101355206
DNA replication proteins [BR:
tmu03032
]
Eukaryotic type
DNA Replication Termination Factors
Other termination factors
101355206
Chromosome and associated proteins [BR:
tmu03036
]
Eukaryotic type
Meiosis-specific proteins
DSB formation-related proteins
101355206
DNA repair and recombination proteins [BR:
tmu03400
]
Eukaryotic type
Check point factors
Other check point factors
101355206
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
FAT
TAN
Htt_N-HEAT_1
Motif
Other DBs
NCBI-GeneID:
101355206
NCBI-ProteinID:
XP_023592722
UniProt:
A0A2Y9RMG5
LinkDB
All DBs
Position
Unknown
AA seq
2331 aa
AA seq
DB search
MSLALNDLLICCRHLEHDRATERRKEVEKFKRLIRDPETVQHLDRHSDSKPGKFLNWDAV
FRFLQKYIQKETECLKTAKPNVSASTQSSRQKKMQEISSLVKYFIKCANKRAPRLKCQEL
LNYIMDTVKDSSNGAIYGADYSNILLKDILSVRKYWCEISQQQWLELLSVYFRLYLKPSQ
DINRVLVARIIYAVTKGYCSQTDGLNPKFLEFFSKAVQCARQEKSSPGLNHVLAALTIFI
KILAINFRIRVCELGDEILPTLLYIWTQHRLNDSLKEVIIELFQLQIYIHHPKGAKTQEK
GAYESAKWRSILYNLYDLLVNEISHIGSRGKYSSGSRNIAVKENLIELMADICHQVFNEN
TRSLEISQSYTTTQRELSDYSVLCKRRRIELGWEVIKDHLQKSQNDFDLVPWLQIATQLI
SKYPASLPNCELSPLLIILSQLLPQQRRGERTPYVLRCLMEVALCQGKISNLEGSQKSDL
LKLWIKIWSITFRSISSEQIQAENFSLLGAIIQGSLVEVDREFWKLFTGSACRPSCPAVC
CLTVALTICVIPETAKTGLEQNISEVNRSVSLRELIMKWLIFYQLEDDLEDTTELPPILH
SKFPHLSLEKILVSLAVKNCKAAMNFFQSAPECEEHQKSKEEPSFLEIEDLFLQTTFDKM
DFLTIVKECGIEKHQSSIGFSVHQNLKESLDRYLLALSEQLLNNYTSETTNPETLVQCSS
LLVGVLGCYCYVGVIAEEDAYKSELFQKAKSLMQCAGESITLFKNKTNEESRIDSLRNML
LLCTSYLCNCMKHNPNKIASGFFLRLLTSKLMNDIADICKSLASFIRKPFDYGEVESVED
DTDENLMEVEDQSPMNLLDVYSAYSVSDANESGESQSITGAANPLAEEYLSKQDLLFLDM
LKFLCMCVTTAQTSIVSFRAADIRRKLLMLIDSSMLDLTKSLHLHMYLVLLKKLPGEDYP
LPMEDVIELLKPLSNVCSLYRRDQDVCKTILNHVLHIVKNLGQGNMDSENTRDAQGQFLT
VIGAFWHLTKDGKCAPTVRVALVKCLKTLLEADPYSKWAILNVMGKEFPVNEVFPQFLAD
NHHQVRMLAAESINRLFQDMKQRDSSRLLKALPLKLQQTAFENAYLKAQEGMREVSHSAE
NPELLDELYNRKAVLLMMIAVVLHCSPVCEKQALFALCKSVKENGLEPHLIKKVLEKVSE
GFGYRHLEDFMTSHLDYLVLEWLNHQDTEYSLSSFPFILLNYTNLEDFYRSCYKVLIPHL
VIRSHFDEVKSIANQIQEDWKSLLTDCFPKILVNILPYFAYEDTGDSGMSQQRETAAKVY
EMLKDESLLGKQIDHLFISNLPEIVVELLMTLHEPGDSGASQSTDLCDFSGDLDPAPNPP
YFPSHVIKATFAYISNCHKTKFKSILEILSKSPDSYQKILLAICEQAAETNNVYKKNRIL
KIYHLFVSLLLKDIKSGLGGAWAFVLRDVIYTLIHCINKRPSCFMDVSLRSFSLCCDLLS
RVCQTAVTYCKDALESHLHVIVGTLIPLVDDQSEVREQVLDLLKYLVIDNKDNENLYLTI
KLLDPFPDHVVFKDLRITQQKIKYNRGPFSLLEEIKHFLSVSVYDALPLTRLEGLKDLRR
QLEQHKDQMKDLMRASQENPQDGIMVKLVVSLLQLSKMAANHTGEREVLEAVGSCLGELG
PIDFSTIAIQHSKDASYNKALELFEDKELQWIFIMLTHLNNTLVEDCVRVRSAAVTCLKS
ILATKAGHSFWEIYKMTTDPMLTYLQPFRTSRKKFLEVPRLDKENPLEDLDDTSLWIPQS
ENHDVWIKTLTCAFLDSGGLKSEVLQLLKPMCEVKTDFCQTVLPYLIHDILLQDTNESWR
NLLSTHIQGFFTNCFRHSSQTSQSTTPVNLDSESEHIFRGYLDKKSQRTMLAVVDYMRRQ
KRPFSGTVFDDAFWLDLNYLEVAKVAQSCAAHFTALLYAEIYADQKNMDDQEKRSLTFEE
GSQSTSISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGKILQPLTRIRTYEHE
AMWGKALVTYDLETAITSSTRQAGIIQALQNLGLCHILSTYLKGLDDENKEWCAELQELH
YQAAWRNMQWDQCNSVSRGLEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEELC
KGSLESVYSLYPTLSRLQAIGELENVGELFSRSVTDRQLSEVYVKWQKHSQLFKDSDFSF
QEPIMALRTVILEILMEKEMESSQRECFKDILTKHLVELSILARTFKNTQLPERAIFQIK
QYNSTSCGVSEWQLEEAQVFWAKKEQSLALNILKQMIKKLDASCTEVTFFY
NT seq
6996 nt
NT seq
+upstream
nt +downstream
nt
atgagtctagcgcttaatgatctgcttatttgctgccgtcatctagaacatgatagagct
acagaacggaggaaagaagttgagaaatttaagcgccttattcgggatcctgaaacagtt
caacatttagatcggcattcagattccaagccaggaaaatttttgaactgggatgctgtt
tttagatttctacagaaatatattcagaaagaaacagaatgtctgaaaacagcaaaacca
aatgtatcggcttcaacacaatcttccaggcagaaaaagatgcaagaaatcagtagcttg
gtcaaatacttcattaaatgtgcaaataaaagagcacccaggctaaaatgccaagaactc
ttgaattacatcatggatacagtgaaagattcatctaatggtgccatttatggagctgat
tatagcaacatactgctcaaagacattctttcagtgagaaaatactggtgtgaaatatct
cagcaacagtggctagaattgttgtctgtgtacttcaggttgtatctcaaaccttcacaa
gacattaatagagttttagtggccagaataatttacgctgtgaccaaaggatactgttca
caaactgatggattaaatcccaaatttttggaatttttttccaaggctgttcagtgtgca
agacaagaaaagagctctccaggcctaaatcatgtcttagcagcacttactatcttcatc
aagattttggccatcaactttcgcattcgagtgtgtgaattaggagatgaaattcttcct
accttgctttatatttggactcaacatagacttaatgattccttaaaagaagtgattatt
gaattatttcaactgcaaatttatatccatcatccaaagggagctaaaacccaagaaaaa
ggtgcttatgagtcagcaaaatggcgaagtatcttatacaatttatatgatctgctagtg
aatgagataagtcatataggaagtagaggaaaatattcttcaggatctcgtaatattgct
gttaaggaaaacttgattgagttgatggcagatatttgtcaccaggtttttaatgaaaat
accagatctttggagatttctcagtcttatactaccacacaaagagaacttagcgactac
agtgtactttgcaaaaggaggagaatagaattaggctgggaagtaattaaagatcatctt
cagaaatcacagaatgattttgatcttgtgccttggttacagatcgcaactcaattaata
tcaaagtatcctgcaagtttacctaactgtgagctatcaccactactgataatactatcc
cagcttctacctcaacagcgacgtggggagcgcacaccatatgtgttacgatgtcttatg
gaagttgcattgtgtcaaggaaagatttcaaatctagaaggctcacaaaagtcagattta
ttgaaactctggattaaaatttggtctattacctttcgcagtataagttctgaacaaata
caagctgaaaacttcagcttacttggagccataattcagggcagtttagttgaggttgat
agagaattctggaagttatttactgggtcagcctgcagaccttcatgtcctgcagtatgc
tgtttgacagtggcactgaccatatgtgtaattccagaaacagcaaaaacaggattagag
cagaatataagcgaagtgaatagaagtgtttcattaagggaattgataatgaaatggctc
atattctatcagttagaggatgacttagaagacactacagagctgcctccaattcttcac
agtaaatttcctcatctttcactggagaaaattcttgtgagtctcgctgtgaaaaactgt
aaagctgcaatgaattttttccaaagtgcgccagaatgtgaggaacaccaaaaaagtaaa
gaagaaccttcattcttagaaatagaagacctatttcttcagacaacttttgacaagatg
gattttttaaccattgtgaaagaatgtggtatagaaaagcaccaatccagtattggattt
tctgtccaccaaaatctcaaggaatcactggatcgctatcttctggcattatcagaacag
cttctaaataattacacatccgagactacaaatccagaaacgcttgtgcagtgttcaagt
cttttggtgggtgttcttggctgctattgttatgtgggtgtaatagccgaagaagacgca
tataaatcagaattattccagaaagccaagtccctaatgcagtgtgcaggagaaagtatc
actctgtttaaaaataagacaaatgaggaatctagaattgattcgttgagaaatatgctt
cttctatgtacaagttacttgtgcaactgtatgaagcacaatccaaataagatcgcatct
ggcttttttctacgattgttaacatcaaagcttatgaatgacattgcagatatttgtaaa
agtttagcatcctttatcagaaagccatttgactatggagaagtagaatcagtggaagat
gatactgatgaaaatctaatggaggtggaggatcagtcacccatgaatctacttgatgtt
tactctgcttatagtgttagtgatgcaaatgaatctggagagagccaaagtattactggt
gctgcaaaccctttggcagaagaatatctgtcaaagcaagatctactttttttagacatg
ctcaagttcttgtgtatgtgtgtaactactgcccagaccagtatagtatcatttagagca
gctgatattcggcggaaactgttaatgttaattgattctagcatgctggatctaactaaa
tcccttcatctacacatgtatctagtgcttttaaagaagcttccaggagaagactatccc
ttgccaatggaagatgtcatcgaacttctgaaacctctatccaacgtgtgttctttgtat
cgccgtgaccaggatgtttgtaaaacaattttaaaccatgtccttcatatagtaaaaaac
ctgggtcaaggcaatatggacagtgagaacacaagagatgctcaaggacagtttctaaca
gtgattggagcattttggcacttaacaaaggacgggaaatgcgcacctactgtaagggtg
gcactagtaaaatgccttaagactctgcttgaggctgatccttattcaaaatgggctatt
ctaaatgtaatgggaaaagagtttcctgtaaatgaagtatttccacaatttcttgctgat
aatcatcaccaagttcgaatgttggctgcagagtcaatcaatagattattccaggatatg
aaacaaagagattcttccagattattgaaagcacttcctttgaaacttcagcaaacagct
tttgaaaatgcatacttgaaagctcaagaaggaatgagagaagtgtcccacagtgctgag
aaccctgaacttttggatgagctttacaacagaaaagctgttttactgatgatgatagct
gtggttttacactgtagccctgtctgtgaaaaacaggctttgtttgccctctgcaaatct
gtgaaagagaatggattagaacctcacctcattaaaaaggttttagagaaggtgtctgaa
ggttttggatatagacatttagaagatttcatgacttctcacttagattatctagttttg
gagtggctaaatcatcaagatactgaatacagcttatcttcgtttccttttattttatta
aactacacaaaccttgaggatttctacagatcttgttataaggttttgatcccacatctg
gtgataagaagtcattttgatgaggtgaagtccattgctaatcagattcaagaggattgg
aaaagccttctaacagactgctttccaaagattcttgtaaatattcttccttattttgcc
tatgaggatacaggagacagtgggatgtcacagcaaagagagactgctgccaaagtctat
gaaatgctcaaagatgaaagcttgttaggaaaacagattgatcatttattcattagtaat
ttaccagagattgtggtggaattattgatgacgttacatgaaccaggagattctggtgcc
agccaaagcactgacctctgtgacttttcaggggatttggatcctgctcctaatccacct
tattttccatctcatgtgattaaagcaacatttgcctatatcagcaattgtcataaaacc
aagtttaaaagcattttagaaattctttccaaaagccctgattcctaccagaaaattctt
ctagccatatgtgagcaagcggctgagacaaataatgtgtataaaaagaatagaattctt
aaaatatatcacctgtttgttagtttattactgaaggatataaaaagtggcttaggagga
gcttgggcctttgttcttcgagatgttatttatactttgattcactgcatcaacaaaagg
ccttcttgtttcatggatgtgtcattacgtagtttctcgctttgttgtgacctattaagc
cgggtttgccagacagcagtgacttactgtaaggatgcgttagaaagccatcttcatgtt
attgttggtacacttataccccttgtggatgatcagtcggaggttcgggaacaggtattg
gacttgttgaaatacctagtgatagataacaaggataatgaaaacctctatctcacaatt
aaacttttagatcctttccctgaccatgttgtttttaaggatttgcgtattacgcagcag
aaaatcaaatacaatagaggacctttttcactcttggaggaaattaaacattttctctca
gtaagtgtttatgatgcacttccattgacaaggcttgaaggattgaaggatcttcgaaga
caactggaacaacataaagatcagatgaaggatcttatgagagcttctcaggaaaaccca
caagatggcattatggtgaagctagttgtgagcttgttgcaactatccaagatggcagca
aaccacactggggaaagagaagttttagaggctgttggaagctgcttgggagaattgggt
cctatagatttctcgacaatagctatacaacatagtaaagatgcatcttacaataaggcc
cttgagttatttgaagataaagaacttcagtggattttcataatgctgacccatctgaat
aatacactagtagaagattgtgtcagagttcgatcagctgctgttacctgtttgaaaagc
attttagccacaaaggctggacacagtttctgggagatttataagatgactactgatccc
atgctcacctatctacagccttttagaacatcgagaaaaaagtttttagaagtacccaga
cttgataaagaaaatcctttagaagacctggatgatacaagtttgtggattcctcaaagt
gaaaatcatgatgtttggataaaaacactgacttgtgcttttttggatagtggaggctta
aaaagtgaagttcttcagttattaaagccaatgtgtgaagtgaaaactgacttttgtcag
actgtgcttccatatttgattcatgatattttgctgcaagatacaaatgaatcatggaga
aatctgctttctacgcatattcagggatttttcaccaactgcttcagacattcctcacaa
accagccaatccacaacccctgtgaatttggattcagagtcagaacacattttccgagga
tatttggataaaaaatcacaaagaacaatgcttgctgttgtggactacatgagaagacaa
aaaagacctttctcaggaacagtttttgatgatgctttctggctggatttgaattatcta
gaggttgccaaggtcgctcagtcttgtgctgctcactttacagcattgctctatgcagaa
atctatgcagatcagaaaaacatggatgatcaagagaaaaggagtcttacatttgaagaa
ggaagccagagtacaagtatttctagtttgagtgaaaaaagtaaagaagaaactggaata
agtttacaggatcttctcttagaaatctatagaagtataggagagccggatagcctgtat
ggctgtggtggagggaaaatattacaaccccttactagaatacgcacatatgaacatgaa
gcaatgtgggggaaagccttagtaacatatgaccttgagacagcaatcacctcatcaacc
cgccaggcaggaataattcaggccttacagaatttgggactctgccatatcctttccacc
tatttaaaaggattagatgatgaaaataaagagtggtgtgctgaactacaggaacttcat
taccaggcagcatggaggaacatgcagtgggaccagtgcaattctgtcagcagaggactg
gaaggaaccagttaccatgaatccttgtacaatgctcttcagtctttaagagacagagag
ttttccacattttatgaaagtctcaaatacgccagagtgaaggaagtggaagaattgtgt
aagggcagccttgagtctgtgtattcgctctaccctacacttagcagattgcaggccatt
ggagagctggaaaacgttggggagcttttctcaagatcagtcactgataggcagctctct
gaagtatatgttaaatggcagaaacactcccagcttttcaaggacagtgattttagtttt
caggagcctattatggctctgcgcacagtcattttggagatcctgatggaaaaggaaatg
gaaagctcccaaagagaatgttttaaagacattctcaccaagcaccttgtggaactctct
atactggcccgaactttcaagaacactcagctccctgaaagggcaatatttcaaattaag
cagtataattcaactagttgtggagtctctgagtggcagctggaggaagcgcaagtattc
tgggcaaaaaaggagcagagtcttgccctgaacattcttaagcaaatgatcaagaagttg
gatgccagttgtacagaggttacttttttttattga
DBGET
integrated database retrieval system
