Thermoanaerobacter pseudethanolicus: Teth39_0689
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Entry
Teth39_0689 CDS
T00649
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
tpd
Thermoanaerobacter pseudethanolicus
Pathway
tpd00290
Valine, leucine and isoleucine biosynthesis
tpd00620
Pyruvate metabolism
tpd01100
Metabolic pathways
tpd01110
Biosynthesis of secondary metabolites
tpd01210
2-Oxocarboxylic acid metabolism
tpd01230
Biosynthesis of amino acids
Module
tpd_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tpd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Teth39_0689
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Teth39_0689
Enzymes [BR:
tpd01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Teth39_0689
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
AAA_lid_5
Motif
Other DBs
NCBI-ProteinID:
ABY94351
UniProt:
B0K7V2
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Position
741722..743284
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AA seq
520 aa
AA seq
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MRNIRIYDTTLRDGVQGQGISFTVEDKLKIVKVLDEFGVAYIEAGNPGSNPKDIEFFERV
KSIKLKNAKLIAFGSTRRANTTTKEDANVISLLNADTEVVTIFGKSWDFQVTEILKTTLE
ENLKMIYDTVKFFKDKGKSVIFDAEHFFDGYKQNPEYALKTLEVALEAGVDSVCLCDTKG
GAFPMEVYDITKTVVDKFNTEVGIHCHNDNGMAVADSIMAVQAGAIQLQGTINGYGERCG
NANLCTLIPNLQLLMGYKCVPDENLKQLTHLARFVSEIANVTYDERAPYVGKNAFSHKAG
MHADAVNKNTYSYELIDPSLVGNSRTFLISEVAGRGTVLNAINEIDPTITKDSPETKLIL
DKLKEMEYLGYQYENAGGSLELLIRKVLGKYKPAFNLKEFKVIVNEPSVNSVNSSALIKV
EVDSIEEIAAAEGDGPVHALDNAVRRVLERFYPQIKEMRLTDYKVRVLDSNSATAAKVRV
IIESTDGKDSWSTIGVSTDIIEASWRALVDSIEYKLNKES
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
gtgaggaacatacggatatacgacacaacattaagagacggagttcaaggacaaggtata
tcttttactgtagaagacaaattaaagatagttaaggttcttgatgagtttggtgtagcc
tatattgaggcaggtaatcctgggtctaatcctaaagatattgaattttttgaaagagtt
aaaagtattaaattaaaaaatgctaaattaatcgcttttggcagcacaagaagagcaaat
acaactaccaaagaggatgctaatgtgatttctcttttaaatgctgacacagaggtagta
actatttttggcaagtcatgggattttcaagttacagaaattttgaaaaccactttagaa
gaaaacttaaaaatgatttatgatacagtaaagttttttaaagacaaaggtaagtcagtt
atatttgatgcagagcatttttttgatggttacaaacaaaatccagagtatgctttaaag
acattagaagtagcattagaggcgggagtagacagtgtttgtttgtgtgatacaaaaggt
ggagcttttccgatggaagtttatgatataacaaaaactgttgtagataaatttaatacg
gaagtaggaatacattgtcacaatgataacggaatggctgttgcagattctataatggca
gtacaagcaggggcaatacagctgcagggtacaataaatggctatggggaaaggtgtggc
aatgcgaatttatgtaccttgataccgaatttgcaattacttatgggatataaatgtgtg
cctgatgaaaatctaaaacaattgactcatttagccagatttgtaagtgaaattgcaaat
gtcacttacgatgaaagggcgccttatgttgggaaaaatgctttttcccacaaagcgggg
atgcatgctgatgctgtaaataaaaatacttattcttatgaactgattgacccttcttta
gtgggaaatagtaggacctttttgatttctgaagttgcaggcagaggaacagtgctaaat
gccataaatgaaatagatccaactattacaaaggattctcctgaaacaaagttaatttta
gataaattaaaagaaatggagtatttagggtatcaatatgaaaatgcaggaggttcttta
gaacttttgataagaaaggttcttggaaaatataaaccagcatttaatttaaaagagttc
aaagttattgtaaatgagccttctgtaaatagtgttaattcttcagcacttataaaagtg
gaagtcgatagtatagaggagatagctgcagctgagggagatgggccagtacatgctctt
gataatgctgtaagaagagtactggagagattttacccacagataaaagaaatgaggttg
acagattataaagtgagggttttggattctaattctgcaactgctgctaaagttagagtt
ataatagagtcgacagacggaaaagattcatggagcacaattggggtttctacagatatt
attgaggccagttggagagcccttgttgattcaatagagtacaaacttaacaaagaaagt
taa
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