Thermacetogenium phaeum: Tph_c08460
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Entry
Tph_c08460 CDS
T02276
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase 2
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
tpz
Thermacetogenium phaeum
Pathway
tpz00230
Purine metabolism
tpz01100
Metabolic pathways
tpz01110
Biosynthesis of secondary metabolites
Module
tpz_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tpz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
Tph_c08460 (purL)
Enzymes [BR:
tpz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
Tph_c08460 (purL)
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Gene cluster
GFIT
Motif
Pfam:
AIRS
AIRS_C
FGAR-AT_linker
TOBE
Motif
Other DBs
NCBI-ProteinID:
AFV11076
UniProt:
K4LDJ6
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All DBs
Position
874558..876759
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AA seq
733 aa
AA seq
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MAEKKPAWQEMGLTAQEYERICEILGREPNYLETGIFAVLWSEHCSYKNSRPVLKRFPTE
GRHVLQGPGENAGIVDIGDGQGVALKIESHNHPSAIEPYQGAATGVGGIVRDIFAMGARP
VALLNSLRFGSLADPRVRYLFSGVVAGISGYGNCLGIPTVGGDVFFHPSFRENPLVNAMC
VGLVEHAQIRRGQAAGVGNSVMVVGARTGRDGIHGCTFASEELSEESEERRPAVQVGDPF
LEKLLIEACLEVIKKGYVVGIQDLGAAGLTSSSAEMAGRAGTGMEIDVSLVPRREEGMTP
YEVMLSESQERMLLVLEPRHVEPVRRIFSKWGLEAAVIGRVTGDGIYRVLDGENPVAEIP
VKALTDSPVYYPEQREPEYYQRLRSWTPDALPEPEDLTAVLRQLLASPNIASKEWIYTQY
DHMVMLNTVVGPGADAAVLRVKGTPKGIALTTDGNPRYCYLDPYRGGAIAVAEAARNLSC
VGAEPLGLTDCLNFGNPGKPEIYWQFTRTVEGMSEACRALGIPVVSGNVSFYNETDGEAI
HPAPVVGMVGLLPDVARHVTGAFRDPGDEIVLLGRFAPTLGASEYLSVIHGLEAGAVPHL
DLDREKRVQECCRSLVREGLIKSAHDCAEGGLAVALAECCLAGKLGATVELPFSGRLDEL
LFGEVQSCIVVSCAPAQLPAVVREAAARGVDCRVIGTTGGGHLLIADAGGSVVTKISVEE
MKEVWRGSIASYF
NT seq
2202 nt
NT seq
+upstream
nt +downstream
nt
atggccgagaagaagcctgcctggcaggagatggggttgacggcacaggagtatgagagg
atctgcgagatcctcggacgggagcccaactatctggaaacggggatcttcgcagtactc
tggtcggagcattgcagttataagaattcccgccctgttttaaagaggttcccgacagag
ggcaggcatgttctgcagggccccggggagaatgccgggatagtggacatcggtgacggc
cagggagtggccttgaagatagagagccacaaccatccttcggccatcgaaccctaccag
ggagcggctactggggtaggggggattgtgcgggatatcttcgcgatgggggcgcgcccc
gttgctttgttgaactccctgcgcttcggaagtcttgccgacccccgggtgcgctatctc
ttctccggcgtagtggccggaatctccggctatggtaactgcctcggcattcccaccgtc
ggcggggatgtctttttccatcccagcttcagggagaaccccctggtcaacgccatgtgc
gtcggtctggtggaacacgctcagatcaggcgcgggcaggctgcaggggtgggcaattcg
gtaatggttgtgggcgcccggacgggcagggacgggatccacggctgcacctttgcctct
gaggaattgagcgaggagagcgaggagcgccgcccggccgtgcaggtcggtgaccctttt
ctggagaagctcctcatcgaggcctgcctggaggttattaaaaagggctatgtcgtcggc
attcaggatttgggagcggcggggctgaccagctccagcgccgaaatggccggaagggcc
ggcacggggatggagatcgatgtttccctggtgccgcgccgggaggagggaatgacaccc
tatgaggtgatgctttccgaatcccaggaacggatgctgctcgttttggagccgcggcat
gtggagccggtgagacggatattcagcaaatgggggctggaagccgcagtgatcggccgg
gtgaccggggacgggatctaccgcgtcctggatggtgagaaccctgtggccgagatacca
gtcaaagccctgaccgattccccggtttactacccggagcagcgggagcccgaatattac
cagaggctgcgaagctggacgccggacgccctccctgagccggaggacctgaccgccgtg
ttgcgccaacttttggcatcaccgaacatcgccagcaaggagtggatttatacccagtac
gaccacatggtgatgctgaataccgtggtggggccgggggccgatgccgccgttctgcgc
gttaagggaacgcccaaggggatcgccctgaccaccgacggaaacccccgctactgctac
ctggatccctatcgcggcggggctattgccgtcgccgaagcggcgcgcaaccttagctgt
gtgggggcggagcccttggggctcaccgactgcttaaacttcggcaatcccgggaagccg
gagatctactggcagttcaccagaaccgtcgaggggatgagcgaggcctgccgcgctctg
gggatccctgttgtcagcggtaatgtgagcttttataatgaaacagatggagaggccatt
catcctgccccggtggtggggatggtgggcctcctgccggatgtggcgcggcatgtcacc
ggcgccttcagagatcccggggacgagatcgtgctgttggggaggtttgctccgacgctc
ggtgccagcgaatacctgtccgtgatccacggattggaggccggagccgttccgcatctc
gacctcgaccgggaaaaaagagttcaggaatgctgccgcagtctggtgcgagaagggctg
atcaaatccgctcacgactgtgcggagggagggctcgccgtggctttggccgagtgttgc
cttgccggcaaactgggtgcgaccgtggaacttcccttctccgggcggcttgatgagctc
ctttttggcgaagtgcagtcttgtattgtggtttcctgcgccccggctcaattgcctgcc
gttgtccgggaggcggccgcacggggtgtcgactgccgggtaatcggtacgactggcggg
ggccatctcctgatcgctgatgccggcgggagcgttgtaacgaagatatctgttgaggag
atgaaagaagtatggcgggggagcattgcttcttacttttga
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