Takifugu rubripes (torafugu): 653021
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Entry
653021 CDS
T02386
Symbol
braf
Name
(RefSeq) serine/threonine-protein kinase B-raf
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
tru
Takifugu rubripes (torafugu)
Pathway
tru04010
MAPK signaling pathway
tru04012
ErbB signaling pathway
tru04068
FoxO signaling pathway
tru04150
mTOR signaling pathway
tru04270
Vascular smooth muscle contraction
tru04510
Focal adhesion
tru04810
Regulation of actin cytoskeleton
tru04910
Insulin signaling pathway
tru04914
Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:
tru00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
653021 (braf)
04012 ErbB signaling pathway
653021 (braf)
04068 FoxO signaling pathway
653021 (braf)
04150 mTOR signaling pathway
653021 (braf)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
653021 (braf)
09142 Cell motility
04810 Regulation of actin cytoskeleton
653021 (braf)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
653021 (braf)
04914 Progesterone-mediated oocyte maturation
653021 (braf)
09153 Circulatory system
04270 Vascular smooth muscle contraction
653021 (braf)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tru01001
]
653021 (braf)
Enzymes [BR:
tru01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
653021 (braf)
Protein kinases [BR:
tru01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
653021 (braf)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
C1_2
Pkinase_fungal
Kdo
Motif
Other DBs
NCBI-GeneID:
653021
NCBI-ProteinID:
NP_001032957
Ensembl:
ENSTRUG00000011625
UniProt:
Q4W6L8
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All DBs
Position
18:169725..184821
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AA seq
778 aa
AA seq
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MAALSSAESPPPVLNGDAAERDPGRERGLEELDSGFNSACTTRVPGGAQNEEIWNIKQMI
KLTQEHLEALLDKFGGEHNPPTIYLEAYEEYTSKLDALQQREQQLLEAMGNGTDFPCSPS
PMPALLEVKMGGCVPGVGAQAPNSLAVLQTPTDGSRVNPRSPQKPIVRVFLPNKQRTVVS
ARCGMTVRDSLKKALTMRGLIPECCAVYRMQDGEKKPIGWDTDISWLTLEELHVEVLENV
PLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLL
VSKFFEHHPFTQEEVSSEGTTPVSEVCPSLPPSDSTGSICQSTVSPSKSIPIPPSFRSSE
EDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRVQGLPRSDGGSTTGLSATPPASLPGS
LTNVKVPQKSPCQQRERKSSSSSEDRSKMKTLGRRDSSDDWEIPEGQITLGQRIGSGSFG
TVFKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYTTKPQLAIVT
QWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLT
VKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRLQDKNPYSFQSDVYAFGIVLYEL
MSGVLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMADCLKKKREERPLFPQ
ILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEFSAFK
NT seq
2337 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgttgagcagcgctgagtctccaccgcccgtcttgaacggagacgccgcggag
cgggatccgggcagggagcgcggcctggaggagctggacagcggatttaactcggcgtgt
acgacgcgggttcccggaggtgcgcaaaatgaggagatctggaacatcaaacagatgata
aagctgacacaggaacacttggaggcactcctggataaatttggaggagagcacaaccct
cccaccatatacctggaggcctacgaggagtacaccagtaaactggatgccctgcagcag
agggagcagcagttgttggaggctatgggcaatggtaccgacttcccctgctctccttct
cccatgccagcccttctggaggtcaagatgggcggctgtgtccctggagtgggggctcag
gcccccaacagcctggccgtcctgcagacgcccaccgacggcagccgagtcaaccctcgt
tcccctcagaagcccatcgtacgagttttcctgcccaacaagcaaaggacggtggtgtca
gctcgctgtggaatgactgtgagggactccctgaagaaggcgctgaccatgcgaggcctc
attcctgaatgttgtgccgtctacagaatgcaagacggagagaagaagccgattggctgg
gataccgacatttcctggctcactttagaggagctccacgtggaggttttagagaatgtc
ccgctcaccactcacaactttgtgaggaagaccttcttcacgttggccttctgtgacttc
tgcagaaagctgctgttccagggctttcgctgtcagacctgtggttacaagttccaccag
cgctgcagcacagaggttcctctcatgtgtgtcaactatgaccagctagatttgttgttg
gtctccaagttcttcgaacatcatcccttcacccaggaggaagtgtcatcagagggaacc
acccccgtgtccgaggtctgtccctctctgcccccgtcagactccactgggtctatctgc
cagtctactgtgtccccgtccaagtccattcccattccccccagttttcgctccagtgag
gaggaccaccgaaaccagtttggccagcgggatcgttcctcctcggccccaaatgtccac
attaatacgatcgagcccgtcaacattgatgacctgattcgagtccaggggcttccaaga
tcagatggaggttccaccacaggactgtcggccactcctcctgcctctcttccaggatcc
ttgactaatgttaaggttccacagaaatcgccctgtcagcagagggagcgcaagtcgtcg
tcctcctctgaggaccgcagtaagatgaaaaccttgggccgaagggactccagtgatgac
tgggaaatcccagagggtcagatcactctgggtcagaggataggttctggctcttttgga
actgtcttcaagggaaagtggcacggagacgtagccgtaaagatgttaaacgtcaccgct
ccgacgccgcaacagctccaggccttcaagaatgaagtgggagtcctcaggaaaacccgt
cacgtcaacatcctgctcttcatgggctacaccaccaagcctcagctggccatcgtcacc
cagtggtgcgaaggctccagcctctaccaccacctgcacatcatcgaaaccaagtttgag
atgatcaagctgatcgacatagcccggcagacggctcaaggcatggattaccttcacgcc
aagtccatcatccacagggacctgaagagcaacaatattttcctccatgaggatctgacg
gtgaagatcggtgactttggtctggccacggtcaagtctcgctggagtggctcccaccag
tttgagcagttgtccggctccatattgtggatggccccagaggtgatccggctgcaggac
aagaacccgtacagcttccagtctgacgtctatgcctttggcatcgtgctgtatgagcta
atgtcaggggtgctgccctactccaacatcaacaacagagaccagatcatatttatggtg
ggcagagggtacctgtctcctgacctcagtaaggtacgcagcaactgtcccaaggccatg
aagagactgatggctgactgtctgaagaagaagcgagaggagcgaccgctcttccctcag
atcttggcttcgattgaactgctggctcgctccctacccaaaatccaccgcagcgcctca
gaaccttcattaaatcgagccggcttccagacagaggactttagtttatacgcctgtgcc
tctcccaaaacccccatccaggccggcggctacggggagttttcagcatttaagtaa
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