Tupaia chinensis (Chinese tree shrew): 102484569
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Entry
102484569 CDS
T02978
Symbol
BACE1
Name
(RefSeq) beta-secretase 1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
tup
Tupaia chinensis (Chinese tree shrew)
Pathway
tup05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
tup00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
102484569 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
tup01002
]
102484569 (BACE1)
Enzymes [BR:
tup01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
102484569 (BACE1)
Peptidases and inhibitors [BR:
tup01002
]
Aspartic peptidases
Family A1: pepsin family
102484569 (BACE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
102484569
NCBI-ProteinID:
XP_006161946
LinkDB
All DBs
Position
Un
AA seq
501 aa
AA seq
DB search
MAPALPWLLLWVGCGLLPAQGTQHGIRLPLRSGLGGNPLGLRLPRETDEEPEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGTGFPLNQSEVLASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLNMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggccccagccctgccctggctcctgctgtgggtggggtgcgggctgctgcccgcccag
ggcacccagcacggtatccggctgcccctgcgcagcggcctcggggggaacccgctgggg
ttgcggctgccccgggagaccgacgaggagcccgaggagccgggccggaggggcagcttc
gtggagatggtggacaacctgcggggcaagtcgggccagggctactacgtggagatgaca
gtgggcagccccccccagacgctcaacatcctggtggacacaggcagcagcaacttcgca
gtgggggcagccccccaccccttcctgcatcgctactaccagaggcagctgtccagcaca
taccgggacctccggaagggcgtgtacgtgccctacacccagggcaagtgggagggggag
ctgggcaccgacctggtgagcatcccccacggtcccaacgtcaccgtgcgtgctaacatc
gctgccatcacggagtcggacaagttcttcatcaatggctccaactgggagggcatcctg
ggactggcctatgctgagatcgccaggcccgacgactccctggagcccttctttgactcc
ctggtgaagcagacccacgttcccaacctcttctccctgcagctctgtggcactggcttc
cccctcaaccagtctgaagtgttggcttcagtcggagggagcatgatcattgggggtatc
gaccactcgctgtacacgggcagtctctggtacacgcccatccggcgggagtggtattac
gaggtgatcatcgtgcgggtggagatcaacggacaagatctgaacatggactgcaaggag
tacaactacgacaagagcatcgtggacagtggcaccaccaaccttcgtctgcccaagaag
gtgtttgaagccgctgtcaagtccatcaaggcggcctcctcgacagagaagttcccggac
gggttctggctgggagagcagctggtgtgctggcaggcgggcaccaccccctggaacatc
ttcccggtcatttcactctatctgatgggtgaggtcaccaatcagtccttccgcatcacc
atcctcccacagcaatacctgcggcctgtggaagacgtggccacgtcccaggacgactgt
tacaagtttgccatctctcagtcctccacgggcaccgtcatgggcgctgtcatcatggag
ggcttctacgtcgtcttcgatcgggcccggaaacgaattggcttcgccgtcagcgcttgc
catgtgcacgatgagttcaggacggcggcagtcgagggccccttcgtcaccccggacatg
gaggactgtggctacaacattccacagacggacgagtccaccctcatgaccatcgcctac
gtcatggccgccatctgcgccctcttcatgctgccgctctgcctcatggtgtgtcagtgg
cgctgcctccgctgcctgcgccaccagcacgatgactttgccgacgacatctccctgctg
aagtga
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