Ursus arctos horribilis (North American brown bear): 113243596
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Entry
113243596 CDS
T05909
Symbol
PAK4
Name
(RefSeq) serine/threonine-protein kinase PAK 4
KO
K05734
p21-activated kinase 4 [EC:
2.7.11.1
]
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah04012
ErbB signaling pathway
uah04014
Ras signaling pathway
uah04360
Axon guidance
uah04510
Focal adhesion
uah04660
T cell receptor signaling pathway
uah04810
Regulation of actin cytoskeleton
uah05170
Human immunodeficiency virus 1 infection
uah05206
MicroRNAs in cancer
uah05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
113243596 (PAK4)
04014 Ras signaling pathway
113243596 (PAK4)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
113243596 (PAK4)
09142 Cell motility
04810 Regulation of actin cytoskeleton
113243596 (PAK4)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
113243596 (PAK4)
09158 Development and regeneration
04360 Axon guidance
113243596 (PAK4)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
113243596 (PAK4)
09162 Cancer: specific types
05211 Renal cell carcinoma
113243596 (PAK4)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
113243596 (PAK4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uah01001
]
113243596 (PAK4)
Enzymes [BR:
uah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
113243596 (PAK4)
Protein kinases [BR:
uah01001
]
Serine/threonine kinases: STE group
STE20 family
113243596 (PAK4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PBD
Kinase-like
ABC1
Pkinase_fungal
hnRNP_Q_AcD
RIO1
Kdo
KIND
Motif
Other DBs
NCBI-GeneID:
113243596
NCBI-ProteinID:
XP_026338131
LinkDB
All DBs
Position
Unknown
AA seq
594 aa
AA seq
DB search
MFGKKKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT
SIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPSARARQENGMPAE
PASTARGAPEKAGSQGRGTGRSEAGGSSGDRRRVGPEKRPKSSREGSGGPQESSRDKRPL
SGPDVGSPQPAGLAGGAKAAAGRPFNTYPRADTDHPARGAQGEPHNLAPNGPSAGGLAVP
QSSSSRPPARARGPPSPGVLGPHASEPQLAPPARPVAAPTPAGPPAPGPPGPRSPQREPQ
RVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGRLVAVKKMDLRKQ
QRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQI
AAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVG
TPYWMAPELISRLPYGPEVDIWSLGVMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKN
LHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR
NT seq
1785 nt
NT seq
+upstream
nt +downstream
nt
atgtttgggaagaagaagaaacgggtcgagatctctgcgccatccaacttcgagcaccgc
gtgcacacgggcttcgaccagcacgagcagaagttcacggggctgccccgccagtggcag
agcctgatcgaggagtcggctcgccggcccaagcccctggtggaccccgcctgcatcacc
tccatccagcccggggcccccaagaccatcgtgcggggcagcaaaggcgccaaggatggg
gccctcacgctgctgctcgacgagtttgagaacatgtcggtgacacgctccaactccctg
cggagagacagcccaccgccatctgcccgtgcccgccaggaaaatgggatgcccgcagag
ccggccagcacggccagaggggccccggagaaggcgggcagccaaggccggggcaccggc
cgcagcgaggcgggtggcagcagtggtgacaggcggcgggtggggccagagaagaggccc
aagtcttccagggagggctcagggggaccccaggagtcctcccgggacaaacgccccctc
tctgggcctgacgtcggcagcccacaacctgccggtctggctggtggagccaaagcggca
gctggtcggccctttaacacgtacccgagggccgatacggaccacccggcccggggtgcc
cagggggaacctcacaacctggcccccaacgggccatcagcagggggcctggcggtcccc
cagtcctcctcctcccggcctcccgcccgagcccgcggaccccccagcccgggagtgctg
ggcccccatgcctctgagccccagctggctcctccagcccgccctgtcgctgcccccacc
cccgccgggcccccagcccccgggccccccgggccccgctcaccgcagcgggaaccccag
cgagtgtcgcacgagcagttccgggcagccttgcagctggtggtggaccccggcgaccct
cgctcctacctggacaacttcatcaagatcggcgagggctcgacgggcatcgtgtgcatt
gctaccgtgcgcagctcgggcaggctggtggctgtcaagaagatggacctgcgcaagcag
cagaggcgcgagctgctcttcaacgaggtggtgatcatgcgggactaccagcacgagaac
gtggtggagatgtacaacagctacctggtcggggatgagctctgggtggtcatggagttc
ctggagggcggcgccctcaccgacatcgtcacgcacaccaggatgaatgaggagcagatt
gccgccgtgtgcctggccgtgctgcaggccctgtctgtgctccacgcacagggagtcatc
caccgcgacatcaagagcgactccatcctgctgacccacgacggcagggtgaagctgtca
gacttcgggttctgcgcccaggtgagcaaggaggtaccacggaggaagtcactggtcggc
acgccctactggatggccccagagctcatctctcgccttccctatgggccagaggtggac
atctggtctctgggggtgatggtgatcgagatggtggacggggagcccccctacttcaat
gagccgccgctcaaagccatgaagatgattcgggacaacctgccgccccgactgaagaac
ttgcacaaggtgtcaccctccctgaagggcttcctggaccgcctgctggtgcgtgacccg
gcccagcgggccacggcggctgagctgctcaagcacccattcctggccaaagcgggcccg
cccgccagcatcgtgcccctcatgcgccagaaccgcaccagatga
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