Ursus arctos horribilis: 113245310
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Entry
113245310 CDS
T05909
Gene name
IL6R
Definition
(RefSeq) interleukin-6 receptor subunit alpha isoform X1
KO
K05055
interleukin 6 receptor
Organism
uah
Ursus arctos horribilis
Pathway
uah01521
EGFR tyrosine kinase inhibitor resistance
uah04060
Cytokine-cytokine receptor interaction
uah04061
Viral protein interaction with cytokine and cytokine receptor
uah04066
HIF-1 signaling pathway
uah04151
PI3K-Akt signaling pathway
uah04630
Jak-STAT signaling pathway
uah04640
Hematopoietic cell lineage
uah04659
Th17 cell differentiation
uah04932
Non-alcoholic fatty liver disease (NAFLD)
uah05163
Human cytomegalovirus infection
uah05200
Pathways in cancer
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 Jak-STAT signaling pathway
113245310 (IL6R)
04066 HIF-1 signaling pathway
113245310 (IL6R)
04151 PI3K-Akt signaling pathway
113245310 (IL6R)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
113245310 (IL6R)
04061 Viral protein interaction with cytokine and cytokine receptor
113245310 (IL6R)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
113245310 (IL6R)
04659 Th17 cell differentiation
113245310 (IL6R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113245310 (IL6R)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease (NAFLD)
113245310 (IL6R)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
113245310 (IL6R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
113245310 (IL6R)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04050 Cytokine receptors [BR:
uah04050
]
113245310 (IL6R)
04090 CD molecules [BR:
uah04090
]
113245310 (IL6R)
Cytokine receptors [BR:
uah04050
]
Interleukin receptor families
IL6/12 receptor family
113245310 (IL6R)
CD molecules [BR:
uah04090
]
Proteins
113245310 (IL6R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
IL6Ra-bind
Ig_3
Ig_2
ig
fn3
I-set
Ig_5
Motif
Other DBs
NCBI-GeneID:
113245310
NCBI-ProteinID:
XP_026341088
UniProt:
A0A3Q7UWQ0
LinkDB
All DBs
Position
Unknown
AA seq
466 aa
AA seq
DB search
MLALRCALLTALLAAPGAALAPGGCPAPEVVSDAVTSLPGASVTLLCPGGEPGDAVHWLL
GNRAAGPHQGSWAAVGRKLLLRSVQLSDSGNYSCYQDGRLLGTVRLLVDAPPEEPQLSCF
RKSPLSKVACEWSPRHPPSPTTRATLLVRKFRSVPLGDSQEPCPYAQGSRKFSCRLAVPE
GDNSLYVVSLCVSNSAGSRSSSPQTFEGYGILQPDPPANITVTAVDGNPRWLSVTWQDPP
SWNSYFYRLQFELRYRAERSKTFTTWMVQELRHRCIIYDAWRGMRHVVQLRAREEFGHGS
WSAWSQEATGTPWTESRSPPAESEVSPSTQALTTNEDDESSLSKSSANATSLPVQDSSPV
PLPTFLVAGGSLAFGTLLCVGIVLRFRRTWKLHALKEGKASVHPPYSLGQLVPERPKPTP
GLVPLISPPVSPSSLGSDSTSRPSRPDARGPQSPYDISNRDYFFPR
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atgctggccctgcgctgcgctctgctgacagccctgctggccgcgccgggggccgccctg
gccccagggggctgccccgcgccggaggtggtgagcgatgcagtgaccagcctgcctggg
gccagcgtgaccctgctctgcccgggcggggagccaggagacgccgttcactggctgctg
gggaatcgtgcagcgggcccgcaccagggcagctgggccgctgtgggaaggaagctgctt
ctgaggtccgtgcagctcagcgactctggaaactattcatgttaccaggacggccgcctg
ctcggaaccgtgcgtttgctggtggatgccccccctgaggagccccagctctcctgcttc
cggaagagtcccctcagcaaggtggcctgtgagtggagtcctcggcacccaccgtccccg
acgaccagggccacattactggtgaggaagtttcggagcgtcccgctgggagactcccag
gagccgtgcccgtatgcccaggggtcccggaagttctcctgccggctggcggtcccggag
ggcgacaactccttgtacgtcgtgtccctgtgcgtcagcaacagtgccggaagcaggtcc
agcagtccccagacgtttgagggctacggaatcctgcagcccgacccgcctgccaacatc
accgtcactgctgtggacggaaacccccgctggctcagtgtgacctggcaggaccccccc
tcctggaactcctatttctacaggctgcagtttgagctccgataccgggctgaacggtca
aagacgttcacaacgtggatggtccaggagctccggcaccgctgcatcatctacgacgcc
tggagaggcatgcggcacgtggtgcagcttcgggcgcgggaggagttcggccatggctcc
tggagcgcctggagccaggaggccacgggcaccccttggacagaatccaggagccctcca
gctgagagcgaggtgtccccctccacgcaggcgctgactactaatgaggacgatgaaagt
agtctctctaaaagttctgcaaatgcaaccagcctcccagtgcaagactcttctccagtg
ccactgcccaccttcctggtggccggaggaagcctggccttcgggacgctcctgtgtgtc
ggcatcgtcctgaggttcaggaggacgtggaagctgcatgcactgaaggaaggcaaggcg
agcgtgcacccgccatactcgctgggacagctggtgcccgagagacccaagcccaccccg
gggctggtgcccctcatctccccgccagtgtcccccagcagccttgggtctgacagcacc
tcgaggcccagccggccggatgccaggggcccacagagcccttacgacatcagcaacaga
gactacttcttccccagatag
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