Ursus maritimus (polar bear): 103667420 Help Entry 103667420         CDS       T03271                                  Symbol NOS2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism umr  Ursus maritimus (polar bear) Pathway umr00220   Arginine biosynthesis umr00330   Arginine and proline metabolism umr01100   Metabolic pathways umr04020   Calcium signaling pathway umr04066   HIF-1 signaling pathway umr04146   Peroxisome umr04371   Apelin signaling pathway umr04926   Relaxin signaling pathway umr05010   Alzheimer disease umr05014   Amyotrophic lateral sclerosis umr05022   Pathways of neurodegeneration - multiple diseases umr05133   Pertussis umr05140   Leishmaniasis umr05142   Chagas disease umr05145   Toxoplasmosis umr05146   Amoebiasis umr05152   Tuberculosis umr05200   Pathways in cancer umr05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:umr00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     103667420 (NOS2)    00330 Arginine and proline metabolism     103667420 (NOS2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     103667420 (NOS2)    04066 HIF-1 signaling pathway     103667420 (NOS2)    04020 Calcium signaling pathway     103667420 (NOS2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     103667420 (NOS2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     103667420 (NOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103667420 (NOS2)   09162 Cancer: specific types    05222 Small cell lung cancer     103667420 (NOS2)   09171 Infectious disease: bacterial    05133 Pertussis     103667420 (NOS2)    05152 Tuberculosis     103667420 (NOS2)   09174 Infectious disease: parasitic    05146 Amoebiasis     103667420 (NOS2)    05145 Toxoplasmosis     103667420 (NOS2)    05140 Leishmaniasis     103667420 (NOS2)    05142 Chagas disease     103667420 (NOS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     103667420 (NOS2)    05014 Amyotrophic lateral sclerosis     103667420 (NOS2)    05022 Pathways of neurodegeneration - multiple diseases     103667420 (NOS2) Enzymes [BR:umr01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      103667420 (NOS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 Motif Other DBs NCBI-GeneID:  103667420 NCBI-ProteinID:  XP_040496965 UniProt:  A0A8M1GPI1 LinkDB All DBs Position Unknown AA seq 1128 aa AA seqDB search MLAVSFYSLVTQDDPKCHSLGKHRNESPQSLTGTVKTSPESLIKLDSPPSACPRHVRIKN WGSGMTFQDTLHHKAKGDIACKSKSCLGAIMNPKSLTRGPRDKPTPPDELLPQAIEFVNQ YYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRIQWSNL QVFDARSCSTAKEMFEHICRHLRYATNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAG YQMPDGTILGDPASVEFTQLCIDLGWKPKYSRFDVVPLVLQADGQDPEFFEIPPDLVLEV PMEHPKYEWFRELQLKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTEIGVRDFCDVQRY NILEEVGRRMGLETHKLASLWKDRAVVEINVAVLHSFQKRNVSIMDHHSAAESFMKYMQN EYRSRGGCPADWIWLVPPISGSITPVFHQEMLNYVLSPFYYYQVEAWKTHTWQDEKRRPR RRKIPFKVLVKAVLFSAMLMCKTMASRVRATILFATETGKSETLARDLGALFSCAFNPKV LCMDEYRLRHLEDEQLLLVVTSTFGNGDSPGNGEKLKKSLFLLKELTNKFRYAVFGLGSS MYPQFCAFAHDIDQKLSHLGASQLAPTGEGDELSGQEEAFRSWAVQTFKAACETFEVRGK HRIQIPRLYTCNVTWDPQHYRLVQDSQPLDLERALSSMHAKKVFTLRLKSQRNLQSPQSS RTTLLVELSCEDSRELSYLPGEHLGVCPSNQLALVQGILERVVDGPSPHQPVHLEILSEN GSYWVRDKRLPPCSLSQALTHFLDITTPPTPLLLRKLAQLATEEAERQRLETLCQPSEYN KWKFTNSPTFLEVLEEFPSLRVSAGFLLSQLPILKPRYYSISSSRDRTPTEVHLTVAVLT YRTRDGQGPLHHGVCSTWLSSLKPQDPVPCFVRSAGNFQLPEDPSHPCILIGPGTGIAPF RGFWQQRLHDTKYKGLQAGRMTLVFGCRRPGEDHLYREEMLEMAQNGVLHEVHTAYSRLP GQPKVYVQDILRQRLASEVLRVLLKEHGHLYVCGDVRMARDVAHTLKLLVAAKLRLSEEQ VEDYFFQLKSQKRYHEDIFGAVFPYEVKKDGAAKQPSDPKVTTAYGRS NT seq 3387 nt NT seq  +upstreamnt  +downstreamnt atgctggctgtttccttttacagtctagtgacacaggatgaccccaagtgtcacagcctc ggcaagcaccggaatgagtccccccagtcgctcacagggacagtaaagacgtctccagaa tccctgatcaagctggattcacccccatcggcctgcccgcggcatgtgaggatcaaaaac tggggcagtggaatgaccttccaagacacacttcaccataaggccaaaggggatatcgct tgcaagtccaagtcttgtctgggagccatcatgaaccccaaaagtttgaccagaggaccc agggacaagcctacccccccagacgagcttctgcctcaagctattgaatttgtcaaccaa tattatggttccttcaaagaggcaaaaatagaggaacatctggccagggtggaagcggta acaaaggagatagaaacaacaggaacctatcagctgacgggggatgagctcatcttcgcc accaagcaggcctggcgcaacgctccccgctgcatcgggaggatccagtggtccaacctg caggtcttcgacgcccggagctgttccactgccaaggaaatgttcgagcacatctgcaga cacctgcggtatgccaccaacaacggcaacatcaggtcggccatcaccgtgttcccccag cggagcgatgggaagcatgacttccgggtctggaatgctcagctcattcggtatgccggc taccagatgcctgatggcaccatcctgggggaccccgccagcgtggagttcacccagctg tgcatcgacctgggctggaagcccaagtacagtcgcttcgacgtggtgcccctggtgctg caggcggatggccaagatccagagttcttcgaaatcccacctgaccttgtgctcgaggtg cccatggaacatcccaagtacgagtggttccgtgagctccagctgaagtggtatgccctg cccgcagtggccaacatgctgcttgaggtgggcggcctcgagttcccggggtgccccttc aacggctggtacatgggcacggagatcggggtccgggacttctgtgacgttcagcgttac aacattctggaggaagtgggcagaaggatgggcctggaaacgcacaagctggcctcactc tggaaggaccgggctgtcgttgagatcaatgtcgctgtgctccacagtttccagaagcgg aatgtgagcatcatggaccaccactcagctgcagagtcgttcatgaagtacatgcagaac gagtaccgttcccgagggggctgcccggccgactggatttggctggtccccccgatttct gggagcatcactcctgtgttccaccaggagatgctaaactatgtcctgtcccctttctac tactaccaggtggaagcctggaaaacccacacctggcaggatgagaagcggagaccccgg agaagaaagattccattcaaagtcttggtgaaagctgtgctcttctccgccatgctgatg tgcaagaccatggcttcccgagtcagagccacaatcctctttgcgacggagacaggaaag tcagaaacgctggcccgggacctgggggccttgttcagctgcgcctttaatcccaaggtt ctctgcatggacgagtataggctgcgccatctggaggacgagcagctgctcctggtggtg accagcacgtttgggaatggagactcccctggcaacggagagaaactgaaaaaatctctc ttcttgctgaaagagcttaccaacaagttcaggtatgccgtgttcggcctcggctccagc atgtaccctcagttctgtgcctttgctcatgacatcgaccagaagctgtcccatctgggg gcctctcagcttgccccaacaggggaaggggacgagctcagtgggcaggaggaagccttc cgcagctgggccgtgcaaacctttaaggcggcctgtgagacgttcgaggtgcgaggcaaa caccgcattcagatccccaggctctacacctgcaacgtgacatgggacccacagcactac aggctcgtgcaggactcgcagcctctggacctcgagagagccctcagcagtatgcatgcc aagaaggtgttcaccctgaggctgaaatcacagcggaatctacagagtccccagtccagc cgcaccaccctcctggtggagctctcctgtgaggacagccgcgagctgagctacttgcct ggagagcacctcggggtttgccccagcaaccagctggccctggtgcaaggcatcttggaa agagtggtagacggcccctcaccccaccagcctgtgcacctggagatcctcagtgagaac ggaagctactgggtcagagataagcggctgcccccgtgctcactcagccaggccctcacc cacttcctggacatcaccacccccccaaccccgctgctgctccgaaagctggcacagctg gccacggaagaggccgagaggcagaggctagagaccctgtgccagccctcagaatacaac aagtggaagttcaccaacagccccacattcctggaggtgctggaggagttcccgtccctg cgggtgtctgctggcttcctgctctcccagctccctattctgaaaccccggtactactcc atcagctcctccagggatcgcacacccacggaggtgcacctcaccgtggccgtgctcacg taccgcacccgagatggccaaggtcccttgcaccacggtgtctgtagcacgtggctcagt agcctgaagccccaagacccagtaccctgcttcgtgagaagtgccggcaacttccagctc cctgaggacccctcccatccttgcatcctcatcggacctggcacaggcatcgcccctttc cgcggtttctggcagcagcggctccatgacaccaagtacaaagggctccaggccggccgc atgaccctggtgttcgggtgccgccgcccaggtgaggaccacctgtatcgggaggagatg ctggagatggcccagaatggggtactgcatgaggtgcacacagcctactctcgcctgcct ggccagcccaaggtctatgttcaagacatcctgcggcagcggctggccagcgaggtgctc cgcgtgctgctcaaggagcacggccacctttatgtctgtggggacgtgcgtatggcccgg gatgtggcccataccctgaagctcctggtggctgccaagctgaggctgagtgaggagcag gtggaggactactttttccagcttaagagccagaagcgctatcatgaagatatctttggt gctgtgtttccctacgaggtgaaaaaagatggggcagcgaagcagcccagcgatcccaaa gttacaacagcctacgggagaagttaa

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