Ursus maritimus (polar bear): 103667420
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Entry
103667420 CDS
T03271
Gene name
NOS2
Definition
(RefSeq) nitric oxide synthase 2
KO
K13241
nitric-oxide synthase, inducible [EC:
1.14.13.39
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr00220
Arginine biosynthesis
umr00330
Arginine and proline metabolism
umr01100
Metabolic pathways
umr04020
Calcium signaling pathway
umr04066
HIF-1 signaling pathway
umr04146
Peroxisome
umr04371
Apelin signaling pathway
umr04926
Relaxin signaling pathway
umr05010
Alzheimer disease
umr05014
Amyotrophic lateral sclerosis
umr05022
Pathways of neurodegeneration - multiple diseases
umr05133
Pertussis
umr05140
Leishmaniasis
umr05142
Chagas disease
umr05145
Toxoplasmosis
umr05146
Amoebiasis
umr05152
Tuberculosis
umr05200
Pathways in cancer
umr05222
Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
103667420 (NOS2)
00330 Arginine and proline metabolism
103667420 (NOS2)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
103667420 (NOS2)
04066 HIF-1 signaling pathway
103667420 (NOS2)
04020 Calcium signaling pathway
103667420 (NOS2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
103667420 (NOS2)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
103667420 (NOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103667420 (NOS2)
09162 Cancer: specific types
05222 Small cell lung cancer
103667420 (NOS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
103667420 (NOS2)
05014 Amyotrophic lateral sclerosis
103667420 (NOS2)
05022 Pathways of neurodegeneration - multiple diseases
103667420 (NOS2)
09171 Infectious disease: bacterial
05133 Pertussis
103667420 (NOS2)
05152 Tuberculosis
103667420 (NOS2)
09174 Infectious disease: parasitic
05146 Amoebiasis
103667420 (NOS2)
05145 Toxoplasmosis
103667420 (NOS2)
05140 Leishmaniasis
103667420 (NOS2)
05142 Chagas disease
103667420 (NOS2)
Enzymes [BR:
umr01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
103667420 (NOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
103667420
NCBI-ProteinID:
XP_008693791
UniProt:
A0A384CG13
LinkDB
All DBs
Position
Un
AA seq
1078 aa
AA seq
DB search
MLAVSFYSLVTQDDPKCHSLGKHRNESPQSLTGTVKTSPESLIKLDSPPSACPRHVRIKN
WGSGMTFQDTLHHKAKGDIACKSKSCLGAIMNPKSLTRGPRDKPTPPDELLPQAIEFVNQ
YYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRIQWSNL
QVFDARSCSTAKEMFEHICRHLRYATNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAG
YQMPDGTILGDPASVEFTQLCIDLGWKPKYSRFDVVPLVLQADGQDPEFFEIPPDLVLEV
PMEHPKYEWFRELQLKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTEIGVRDFCDVQRY
NILEEVGRRMGLETHKLASLWKDRAVVEINVAVLHSFQKRNVSIMDHHSAAESFMKYMQN
EYRSRGGCPADWIWLVPPISGSITPVFHQEMLNYVLSPFYYYQVEAWKTHTWQDEKRRPR
RRKIPFKVLVKAVLFSAMLMCKTMASRVRATILFATETGKSETLARDLGALFSCAFNPKV
LCMDEYRLRHLEDEQLLLVVTSTFGNGDSPGNGEKLKKSLFLLKELTNKFRYAVFGLGSS
MYPQFCAFAHDIDQKLSHLGASQLAPTGEGDELSGQEEAFRSWAVQTFKAACETFEVRGK
HRIQIPRLYTCNVTWDPQHYRLVQDSQPLDLERALSSMHAKKVFTLRLKSQRNLQSPQSS
RTTLLVELSCEDRSYWVRDKRLPPCSLSQALTHFLDITTPPTPLLLRKLAQLATEEAERQ
RLETLCQPSEYNKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQLPILKPRYYSISSSRDRT
PTEVHLTVAVLTYRTRDGQGPLHHGVCSTWLSSLKPQDPVPCFVRSAGNFQLPEDPSHPC
ILIGPGTGIAPFRGFWQQRLHDTKYKGLQAGRMTLVFGCRRPGEDHLYREEMLEMAQNGV
LHEVHTAYSRLPGQPKVNAAAACLLASEVLRVLHKEHGHLYVCGDVRMARDVAHTLKLLV
AAKLRLSEEQVEDYFFQLKSQKRYHEDIFGAVFPYEVKKDGAAKQPSDPKVTTAYGRS
NT seq
3237 nt
NT seq
+upstream
nt +downstream
nt
atgctggctgtttccttttacagtctagtgacacaggatgaccccaagtgtcacagcctc
ggcaagcaccggaatgagtccccccagtcgctcacagggacagtaaagacgtctccagaa
tccctgatcaagctggattcacccccatcggcctgcccgcggcatgtgaggatcaaaaac
tggggcagtggaatgaccttccaagacacacttcaccataaggccaaaggggatatcgct
tgcaagtccaagtcttgtctgggagccatcatgaaccccaaaagtttgaccagaggaccc
agggacaagcctacccccccagacgagcttctgcctcaagctattgaatttgtcaaccaa
tattatggttccttcaaagaggcaaaaatagaggaacatctggccagggtggaagcggta
acaaaggagatagaaacaacaggaacctatcagctgacgggggatgagctcatcttcgcc
accaagcaggcctggcgcaacgctccccgctgcatcgggaggatccagtggtccaacctg
caggtcttcgacgcccggagctgttccactgccaaggaaatgttcgagcacatctgcaga
cacctgcggtatgccaccaacaacggcaacatcaggtcggccatcaccgtgttcccccag
cggagcgatgggaagcatgacttccgggtctggaatgctcagctcattcggtatgccggc
taccagatgcctgatggcaccatcctgggggaccccgccagcgtggagttcacccagctg
tgcatcgacctgggctggaagcccaagtacagtcgcttcgacgtggtgcccctggtgctg
caggcggatggccaagatccagagttcttcgaaatcccacctgaccttgtgctcgaggtg
cccatggaacatcccaagtacgagtggttccgtgagctccagctgaagtggtatgccctg
cccgcagtggccaacatgctgcttgaggtgggcggcctcgagttcccggggtgccccttc
aacggctggtacatgggcacggagatcggggtccgggacttctgtgacgttcagcgttac
aacattctggaggaagtgggcagaaggatgggcctggaaacgcacaagctggcctcactc
tggaaggaccgggctgtcgttgagatcaatgtcgctgtgctccacagtttccagaagcgg
aatgtgagcatcatggaccaccactcagctgcagagtcgttcatgaagtacatgcagaac
gagtaccgttcccgagggggctgcccggccgactggatttggctggtccccccgatttct
gggagcatcactcctgtgttccaccaggagatgctaaactatgtcctgtcccctttctac
tactaccaggtggaagcctggaaaacccacacctggcaggatgagaagcggagaccccgg
agaagaaagattccattcaaagtcttggtgaaagctgtgctcttctccgccatgctgatg
tgcaagaccatggcttcccgagtcagagccacaatcctctttgcgacggagacaggaaag
tcagaaacgctggcccgggacctgggggccttgttcagctgcgcctttaatcccaaggtt
ctctgcatggacgagtataggctgcgccatctggaggacgagcagctgctcctggtggtg
accagcacgtttgggaatggagactcccctggcaacggagagaaactgaaaaaatctctc
ttcttgctgaaagagcttaccaacaagttcaggtatgccgtgttcggcctcggctccagc
atgtaccctcagttctgtgcctttgctcatgacatcgaccagaagctgtcccatctgggg
gcctctcagcttgccccaacaggggaaggggacgagctcagtgggcaggaggaagccttc
cgcagctgggccgtgcaaacctttaaggcggcctgtgagacgttcgaggtgcgaggcaaa
caccgcattcagatccccaggctctacacctgcaacgtgacatgggacccacagcactac
aggctcgtgcaggactcgcagcctctggacctcgagagagccctcagcagtatgcatgcc
aagaaggtgttcaccctgaggctgaaatcacagcggaatctacagagtccccagtccagc
cgcaccaccctcctggtggagctctcctgtgaggacagaagctactgggtcagagataag
cggctgcccccgtgctcactcagccaggccctcacccacttcctggacatcaccaccccc
ccaaccccgctgctgctccgaaagctggcacagctggccacggaagaggccgagaggcag
aggctagagaccctgtgccagccctcagaatacaacaagtggaagttcaccaacagcccc
acattcctggaggtgctggaggagttcccgtccctgcgggtgtctgctggcttcctgctc
tcccagctccctattctgaaaccccggtactactccatcagctcctccagggatcgcaca
cccacggaggtgcacctcaccgtggccgtgctcacgtaccgcacccgagatggccaaggt
cccttgcaccacggtgtctgtagcacgtggctcagtagcctgaagccccaagacccagta
ccctgcttcgtgagaagtgccggcaacttccagctccctgaggacccctcccatccttgc
atcctcatcggacctggcacaggcatcgcccctttccgcggtttctggcagcagcggctc
catgacaccaagtacaaagggctccaggccggccgcatgaccctggtgttcgggtgccgc
cgcccaggtgaggaccacctgtatcgggaggagatgctggagatggcccagaatggggta
ctgcatgaggtgcacacagcctactctcgcctgcctggccagcccaaggtaaacgcggca
gcggcctgtctactggccagcgaggtgctccgcgtgctgcacaaggagcacggccacctt
tatgtctgtggggacgtgcgtatggcccgggatgtggcccataccctgaagctcctggtg
gctgccaagctgaggctgagtgaggagcaggtggaggactactttttccagcttaagagc
cagaagcgctatcatgaagatatctttggtgctgtgtttccctacgaggtgaaaaaagat
ggggcagcgaagcagcccagcgatcccaaagttacaacagcctacgggagaagttaa
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integrated database retrieval system
