KEGG   Ursus maritimus (polar bear): 103669544
Entry
103669544         CDS       T03271                                 
Symbol
PPARG
Name
(RefSeq) peroxisome proliferator-activated receptor gamma isoform X1
  KO
K08530  peroxisome proliferator-activated receptor gamma
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr03320  PPAR signaling pathway
umr04148  Efferocytosis
umr04152  AMPK signaling pathway
umr04211  Longevity regulating pathway
umr04380  Osteoclast differentiation
umr04714  Thermogenesis
umr04932  Non-alcoholic fatty liver disease
umr05016  Huntington disease
umr05200  Pathways in cancer
umr05202  Transcriptional misregulation in cancer
umr05216  Thyroid cancer
umr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    103669544 (PPARG)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    103669544 (PPARG)
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    103669544 (PPARG)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103669544 (PPARG)
  09149 Aging
   04211 Longevity regulating pathway
    103669544 (PPARG)
  09159 Environmental adaptation
   04714 Thermogenesis
    103669544 (PPARG)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103669544 (PPARG)
   05202 Transcriptional misregulation in cancer
    103669544 (PPARG)
  09162 Cancer: specific types
   05216 Thyroid cancer
    103669544 (PPARG)
  09164 Neurodegenerative disease
   05016 Huntington disease
    103669544 (PPARG)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103669544 (PPARG)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    103669544 (PPARG)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:umr03000]
    103669544 (PPARG)
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors [BR:umr03310]
    103669544 (PPARG)
Transcription factors [BR:umr03000]
 Eukaryotic type
  Zinc finger
   Cys4 thyroid hormone receptor-like
    103669544 (PPARG)
Nuclear receptors [BR:umr03310]
 1. Thyroid hormone like
  1C. Peroxisome proliferator-activated receptor (PPAR)
   103669544 (PPARG)
SSDB
Motif
Pfam: PPARgamma_N zf-C4 Hormone_recep Tmemb_55A
Other DBs
NCBI-GeneID: 103669544
NCBI-ProteinID: XP_008696091
UniProt: A0A384CMM7
LinkDB
Position
Unknown
AA seq 505 aa
MGETLGDSLIDPESDSFADTLSASTSQEITMVDTEMPFWPTNFGISSVDLSVMDDHSHSF
DIKPFTTVDFSSISTPHYEDIPFARADPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKT
QLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNC
RIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLR
ALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQE
QSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS
LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVII
LSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQL
LQVIKKTETDMSLHPLLQEIYKDLY
NT seq 1518 nt   +upstreamnt  +downstreamnt
atgggtgaaactctgggagattctcttattgacccagaaagcgattcctttgctgataca
ctgtctgcaagcacttcacaagaaattaccatggttgacaccgagatgccattttggccc
accaactttggaatcagctccgtggatctctctgtaatggatgaccactcccattctttt
gacatcaagcccttcaccaccgtggatttctccagcatttccactccacactatgaagac
attccatttgcaagagcggacccaatggttgctgattacaagtatgacctgaagctccag
gagtaccaaagtgcaatcaaagtggagcctgcatccccaccttattattcggaaaagact
cagctgtacaataagcctcatgaagagccttccaactccctcatggcaattgaatgccga
gtctgtggagataaagcttccgggttccactatggcgttcatgcttgtgaaggatgcaag
gggttcttccggaggacaatcagattgaagctcatttatgataggtgtgaccttaactgt
cggatccataaaaaaagtagaaataaatgtcagtactgtcggtttcagaaatgccttgct
gtggggatgtctcacaatgccatcaggtttgggcggatgccgcaggccgagaaggagaag
ctgttggcggagatctccagcgatatcgaccagctgaacccagagtcggctgatctccgg
gccctggcaaaacatttgtatgactcatacataaagtccttcccgctgaccaaagcaaag
gcgagggcgatcttgacaggaaagacaacggacaaatcaccatttgttatctatgacatg
aattccttaatgatgggagaagataaaatcaagttcaaacacatcacccccttgcaggag
cagagcaaagaggtggccattcgcatctttcaggggtgtcagttccgctcagtggaagct
gtgcaggagatcacagagtatgccaaaagtatccctggctttgtaaaccttgacttgaat
gaccaagtaactctcctaaaatatggtgtccatgagatcatttacacgatgctggcctcc
ttgatgaataaagatggggttctcatatcagagggccaaggattcatgacaagggagttt
ctaaagagcctgagaaagccctttggtgactttatggagcccaagtttgagtttgctgtg
aagttcaatgcactggaattagatgacagcgacttggcaatatttatagccgtcattatt
ctcagtggagaccgcccaggtttgctgaacgtgaagcccattgaggacatccaggacaac
ctgctgcaagccttggagctccagctcaagctgaaccaccccgaatcctctcagctcttt
gccaagctgctccagaaaatgacagacctcagacagattgtaacagaacatgtgcagcta
ttgcaagtcataaagaaaacagagacggacatgagtcttcacccgctcctacaagagata
tacaaggacttgtattag

KEGG   Ursus maritimus (polar bear): 103671861
Entry
103671861         CDS       T03271                                 
Symbol
PAX8
Name
(RefSeq) paired box protein Pax-8
  KO
K09293  paired box protein 8
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04918  Thyroid hormone synthesis
umr05200  Pathways in cancer
umr05202  Transcriptional misregulation in cancer
umr05216  Thyroid cancer
Brite
KEGG Orthology (KO) [BR:umr00001]
 09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    103671861 (PAX8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103671861 (PAX8)
   05202 Transcriptional misregulation in cancer
    103671861 (PAX8)
  09162 Cancer: specific types
   05216 Thyroid cancer
    103671861 (PAX8)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:umr03000]
    103671861 (PAX8)
Transcription factors [BR:umr03000]
 Eukaryotic type
  Helix-turn-helix
   Homeo domain Paired-related
    103671861 (PAX8)
SSDB
Motif
Pfam: PAX Pax2_C HTH_23 HTH_32 DUF6115 HTH_Tnp_IS1
Other DBs
NCBI-GeneID: 103671861
NCBI-ProteinID: XP_040479634
UniProt: A0A8M1FG25
LinkDB
Position
Unknown
AA seq 494 aa
MACGHEKPVEGAQKWAIWDVLPAVVEKHVLGQAALSVPATTVFLGHGGLNQLGGAFVNGR
PLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVA
TPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPM
DSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQPGSDSKRKMDDSDQ
DSCRLSIDSQSSSSGPRKHPRTDSFSQHHLEPLECPFERQHYPEAYASPSHTKGEQGLYP
LPLLNSAALDDGKATLTPSNTPLGRNLSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPS
SLSSSAFLDLQQVGSGVPAGASVPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGYPP
HIPTSGQGSYASSAIAGMVAGSEYSGSAYGHTPYSSYSEAWRFPNSSLLSSPYYYSSTSR
PSAPPTTATAFDHL
NT seq 1485 nt   +upstreamnt  +downstreamnt
atggcctgtggccatgagaagccagtggaaggggctcagaagtgggccatctgggatgtc
ctcccagccgtggtggaaaagcacgtgctgggacaagcggccttatctgttcccgcaact
actgtcttcttaggccatggagggctgaaccagctgggaggggcctttgtgaacggcaga
cccctgcccgaagtggtgcgtcaacgcatcgtggacctggcccaccagggggtgaggccc
tgcgacatctcccgccagctccgagtcagccatggctgtgtcagcaagatccttggcagg
tactacgagaccggaagcatccggcctggagtgatagggggctccaagcccaaggtggct
acccccaaggtggtggagaagattggagactacaagcggcagaaccccaccatgtttgcc
tgggagatccgagaccggctcctggcggagggggtctgtgacaatgacactgtgcccagt
gtcagctccatcaacagaatcatccggaccaaagtgcagcaaccgttcaacctccccatg
gacagctgcgtggccaccaagtccctgagcccaggacacacgctgatccccagctcagcc
gtcacgcccccggagtcaccccagtcggactccctgggctccacctactccatcaacggg
ctcctggggatcgctcagcctggcagcgacagcaagaggaaaatggacgacagtgaccag
gacagctgccggctgagcatcgactcccagagcagcagcagcgggccccgcaagcacccg
cgcacggactccttcagccagcaccaccttgagccgctcgagtgcccgttcgagcggcag
cactacccagaggcctatgcctcccccagccacaccaaaggcgagcagggcctctacccg
ctgcccttgctcaacagtgccgccctggacgacggcaaggccaccctgaccccttccaac
acgcctttggggcgcaacctctcgactcaccagacctacccagtggtggcagatcctcat
tcacccttcgccataaagcaggaaacccccgaggtgtccagttctagctccaccccttcc
tctttatctagctccgcctttttggatctgcagcaagtcggctccggggtcccagccggt
gcctcggtcccgcccttcaatgcctttccccatgctgcctccgtgtacgggcagttcacg
ggccaggccctcctctcagggagagagatggtgggacccacgctgcccggatacccaccc
cacatccccaccagcggacagggcagctatgcctcttctgccatcgcaggcatggtggca
ggaagtgaatactctggcagtgcctacggccacaccccctactcctcctacagcgaggcc
tggcgcttccccaactccagcttgctgagttccccgtattattacagttccacatcaagg
ccaagtgcgccacccaccaccgccacggcttttgaccacctgtag

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