Ursus maritimus (polar bear): 103672737
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Entry
103672737 CDS
T03271
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha isoform X1
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr01521
EGFR tyrosine kinase inhibitor resistance
umr04010
MAPK signaling pathway
umr04014
Ras signaling pathway
umr04015
Rap1 signaling pathway
umr04020
Calcium signaling pathway
umr04072
Phospholipase D signaling pathway
umr04144
Endocytosis
umr04151
PI3K-Akt signaling pathway
umr04510
Focal adhesion
umr04540
Gap junction
umr04630
JAK-STAT signaling pathway
umr04810
Regulation of actin cytoskeleton
umr05163
Human cytomegalovirus infection
umr05200
Pathways in cancer
umr05206
MicroRNAs in cancer
umr05214
Glioma
umr05215
Prostate cancer
umr05218
Melanoma
umr05230
Central carbon metabolism in cancer
umr05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103672737 (PDGFRA)
04014 Ras signaling pathway
103672737 (PDGFRA)
04015 Rap1 signaling pathway
103672737 (PDGFRA)
04630 JAK-STAT signaling pathway
103672737 (PDGFRA)
04020 Calcium signaling pathway
103672737 (PDGFRA)
04072 Phospholipase D signaling pathway
103672737 (PDGFRA)
04151 PI3K-Akt signaling pathway
103672737 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
103672737 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
103672737 (PDGFRA)
04540 Gap junction
103672737 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103672737 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103672737 (PDGFRA)
05206 MicroRNAs in cancer
103672737 (PDGFRA)
05230 Central carbon metabolism in cancer
103672737 (PDGFRA)
05231 Choline metabolism in cancer
103672737 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
103672737 (PDGFRA)
05218 Melanoma
103672737 (PDGFRA)
05215 Prostate cancer
103672737 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
103672737 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103672737 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
umr01001
]
103672737 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
umr04090
]
103672737 (PDGFRA)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103672737 (PDGFRA)
Protein kinases [BR:
umr01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
103672737 (PDGFRA)
CD molecules [BR:
umr04090
]
Proteins
103672737 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
VEGFR-1-like_Ig-like
V-set
Herpes_gE
Ig_6
Kinase-like
Motif
Other DBs
NCBI-GeneID:
103672737
NCBI-ProteinID:
XP_008699703
UniProt:
A0A384CY31
LinkDB
All DBs
Position
Unknown
AA seq
1089 aa
AA seq
DB search
MGTSLLAFLILGSLLTGPSRVFCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYP
MSEEENPNVEIRNEENNSGLFVAVLEVVSAAAAHTGLYTCYYNHTQTEETDIEGRRIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLRSNDGVVHASYDSRQGFNG
TFSVGPYICEATVRGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLRVPEATVKDSGDYECAARQATKEVK
EMKKVTISVHEKGFIEIKPNFSPLEAVDLHEVKHFVVDVQAYPPPRISWLKDNLTLIENL
TEITTDIEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWAILANNISNIITEVHPRD
RSTVEGRVTFTRVEETIAVRCLAKNLLGAESRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADDSTRSY
VILSFENNGDYMDMKQADATQYVPMLERKEAAKYSDIQRSLYDRPASSKKKSVLDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDADNAYIGVTYKNEEDKLKDWEGSLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccttctggccttcctgatcttaggctctctcctcacagggcccagccga
gtcttctgccagctttcattaccctccatcctgccaaacgaaaatgaaaaggtcgtgcag
ctgaattcatccttttctctgagatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaaccccaatgtggaaatcagaaacgaggagaacaacagcggcctt
tttgtggccgtgctggaggtggtcagcgcggcggcggcgcacacgggcttgtacacctgc
tattacaaccacacccagacggaggagaccgacatcgagggcaggcgtatctacatctac
gtgccagacccggatgtagccttcgtgcctctgggaatgacagattatttagtcatcgtg
gaggatgatgattctgccatcataccttgtcgcacgactgatcccgagactccggtcacc
ttgcgcagcaatgacggggtggtgcacgcctcctatgacagcagacagggcttcaatggg
accttcagcgttgggccctatatctgtgaagccaccgtcaggggaaagaagttccagacc
atcccatttaatgtttatgctttaaaagcaacgtcagaacttgatctagaaatggaagct
cttaaaactgtgtataagtcaggggagacgattgtggtcacctgcgccgtctttaacaac
gaggtggtcgaccttcagtggacttaccctggagaagtgaaaggcaaaggcatcaccatg
ctggaggaaatcaaggtcccgtccatcaaattggtgtatactctgagggtccccgaggcc
acggtgaaagatagtggagattatgaatgtgctgcccgccaggccaccaaggaggtcaaa
gagatgaagaaagtcaccatttctgtccatgagaaagggttcattgaaatcaaacccaac
ttcagcccgttggaagctgtcgacctgcatgaagtcaaacatttcgtggtggacgtgcag
gcctacccccctcccaggatatcctggctgaaggacaacctgactctgattgaaaatctc
acggagatcaccacggacatagaaaagattcaggaaataaggtatcggagcaaattaaag
ctgatccgtgctaaggaggaagacagtggccattacacgatcgtcgttcaaaatgaagat
gacgtgaagagctatactttcgaactcctaactcaagttccctcatctattctggacttg
gtggacgaccaccacggctccacggggggacagaccgtgagatgcaccgccgaagggacg
cctcttcctgatatcgagtggatgatttgcaaggatattaagaagtgtaataatgaaact
tcatgggcgattttggccaacaatatctcaaacatcatcacggaggtccacccccgagac
aggagcactgtggagggccgagtgacgttcaccagagtggaggagaccatcgccgttcga
tgtctggccaagaatctccttggggccgagagccgcgagctcaagctggtggctcccacg
ctgcgctctgagctcacggtggctgctgccgtcctcgtgctgctggtgattgtcatcatc
tccctcatcgtcctggtcgtcatttggaaacagaaaccgaggtatgaaattcgctggagg
gtcattgaatccatcagcccggatggacatgaatatatttatgtggacccgatgcagctg
ccttatgactcgagatgggagtttccaagagatggactagtgcttggtcgtatcctggga
tctggcgcgtttgggaaagtggttgaaggaactgcctatggattaagccgctcccagcct
gtcatgaaggtagcagtgaagatgctgaaacccacagccagatccagtgagaaacaggct
cttatgtcggaactgaagataatgactcacctggggccgcatttaaacattgtgaacttg
ctgggagcctgtaccaagtcaggccctatttacatcatcactgagtactgcttctatggg
gatttggtcaactatttgcataagaatagggatagcttcctgagccgccacccggagaag
ccaaagaaagagctggacatttttggattgaaccctgccgacgacagcacacggagttac
gtcattttatcttttgaaaacaacggtgactacatggacatgaagcaagctgacgccacc
cagtacgtccccatgctggaaaggaaagaggctgccaagtactcagacatccagagatcg
ctgtatgatcgcccggcctcgtctaagaagaagtctgtgttagactcagaagtcaaaaac
ctcctttcggatgataactcagaaggccttactttgttggatttgttgagctttacctat
caagttgcacgaggaatggaatttttggcttcgaaaaattgtgtccaccgggacctggct
gctcgaaacgtcctcctggcgcaagggaaaatcgtgaagatctgtgacttcggcctggcc
agagacatcatgcacgattcgaactacgtgtcgaaaggcagtacctttctccctgtgaag
tggatggcccctgagagcatcttcgacaacctctacaccacactgagtgacgtctggtct
tacggcattctgctctgggagatcttttccctcggcggcacaccctaccccggcatgatg
gtggattctactttctacaataagattaagagtgggtaccggatggccaagcctgaccac
gccaccagtgaagtctacgagatcatggtgaaatgctggcacagtgagccggagaagaga
ccctccttctaccacctgagtgagattgtggagaacctgctgcccggacagtataagaag
agttacgaaaagattcacctggacttcctgaagagcgaccaccccgccgtggcgcgcatg
cgcgtggacgccgacaacgcctacattggcgtcacctacaaaaacgaggaagacaagctg
aaggactgggagggcagcctggacgagcagaggctgagcgcggacagcggctacatcatc
cccctgcccgacatcgaccctgtccctgaggaggaagacctgggcaagaggaacagacac
agctcgcagacctcagaagagagtgctatcgagacaggttcgagcagctccaccttcatc
aagagagaggacgagaccatcgaggacatcgacatgatggacgacattggcatagactcc
tcagacctggtagaggacagcttcctgtga
DBGET
integrated database retrieval system
