Ursus maritimus (polar bear): 103676495 Help Entry 103676495         CDS       T03271                                  Gene name IGF1 Definition (RefSeq) insulin like growth factor 1   KO K05459   insulin-like growth factor 1 Organism umr  Ursus maritimus (polar bear) Pathway umr01521   EGFR tyrosine kinase inhibitor resistance umr01522   Endocrine resistance umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04066   HIF-1 signaling pathway umr04068   FoxO signaling pathway umr04114   Oocyte meiosis umr04115   p53 signaling pathway umr04150   mTOR signaling pathway umr04151   PI3K-Akt signaling pathway umr04152   AMPK signaling pathway umr04211   Longevity regulating pathway umr04213   Longevity regulating pathway - multiple species umr04510   Focal adhesion umr04550   Signaling pathways regulating pluripotency of stem cells umr04730   Long-term depression umr04750   Inflammatory mediator regulation of TRP channels umr04913   Ovarian steroidogenesis umr04914   Progesterone-mediated oocyte maturation umr04935   Growth hormone synthesis, secretion and action umr04960   Aldosterone-regulated sodium reabsorption umr05200   Pathways in cancer umr05202   Transcriptional misregulation in cancer umr05205   Proteoglycans in cancer umr05214   Glioma umr05215   Prostate cancer umr05218   Melanoma umr05224   Breast cancer umr05410   Hypertrophic cardiomyopathy umr05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103676495 (IGF1)    04014 Ras signaling pathway     103676495 (IGF1)    04015 Rap1 signaling pathway     103676495 (IGF1)    04066 HIF-1 signaling pathway     103676495 (IGF1)    04068 FoxO signaling pathway     103676495 (IGF1)    04151 PI3K-Akt signaling pathway     103676495 (IGF1)    04152 AMPK signaling pathway     103676495 (IGF1)    04150 mTOR signaling pathway     103676495 (IGF1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103676495 (IGF1)    04115 p53 signaling pathway     103676495 (IGF1)   09144 Cellular community - eukaryotes    04510 Focal adhesion     103676495 (IGF1)    04550 Signaling pathways regulating pluripotency of stem cells     103676495 (IGF1)  09150 Organismal Systems   09152 Endocrine system    04913 Ovarian steroidogenesis     103676495 (IGF1)    04914 Progesterone-mediated oocyte maturation     103676495 (IGF1)    04935 Growth hormone synthesis, secretion and action     103676495 (IGF1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     103676495 (IGF1)   09156 Nervous system    04730 Long-term depression     103676495 (IGF1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     103676495 (IGF1)   09149 Aging    04211 Longevity regulating pathway     103676495 (IGF1)    04213 Longevity regulating pathway - multiple species     103676495 (IGF1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103676495 (IGF1)    05202 Transcriptional misregulation in cancer     103676495 (IGF1)    05205 Proteoglycans in cancer     103676495 (IGF1)   09162 Cancer: specific types    05214 Glioma     103676495 (IGF1)    05218 Melanoma     103676495 (IGF1)    05215 Prostate cancer     103676495 (IGF1)    05224 Breast cancer     103676495 (IGF1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     103676495 (IGF1)    05414 Dilated cardiomyopathy     103676495 (IGF1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103676495 (IGF1)    01522 Endocrine resistance     103676495 (IGF1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103676495 (IGF1) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103676495 (IGF1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Insulin DUF2865 Motif Other DBs NCBI-GeneID:  103676495 NCBI-ProteinID:  XP_008703915 UniProt:  A0A384DAX3 LinkDB All DBs Position Un AA seq 184 aa AA seqDB search MGKISSLPTQLFKCCFCDFLKVKMHIMSSSHLFYLALCLLTFTSSATAGPETLCGAELVL CVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARSVRA QRHTDMPKAQKYRPPSTTKKTKSQRRRKGGPKKRPGGEQKVGTETSQQMKGKKKEQRRET GARN NT seq 555 nt NT seq  +upstreamnt  +downstreamnt atgggaaaaatcagcagtcttccaactcaattatttaagtgctgcttttgtgatttcttg aaggtaaagatgcacatcatgtcctcctcgcatctcttctacctggccctgtgcttgctc accttcaccagctctgccacagctggaccggagacgctctgtggggctgaattggttctg tgtgtgtgtggagacaggggtttttatttcaacaagcccacggggtatggctccagcagt cggagggcacctcagacaggcatcgtggatgagtgctgcttccggagctgtgatctgagg aggctagagatgtactgcgcacccctcaagcctgccaagtctgcccgctcagtccgtgcc cagcgccacactgacatgcccaaggctcagaagtatcgtcccccatctaccaccaagaaa acgaagtctcagaggagaaggaaaggtgggccaaagaaacgcccaggaggggaacagaag gtggggacggaaacaagtcagcagatgaaaggaaagaagaaagagcagagaagggagact ggagctagaaactga

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