Ursus maritimus (polar bear): 103682015
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Entry
103682015 CDS
T03271
Symbol
TGFBR2
Name
(RefSeq) TGF-beta receptor type-2
KO
K04388
TGF-beta receptor type-2 [EC:
2.7.11.30
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr04010
MAPK signaling pathway
umr04060
Cytokine-cytokine receptor interaction
umr04068
FoxO signaling pathway
umr04144
Endocytosis
umr04218
Cellular senescence
umr04350
TGF-beta signaling pathway
umr04380
Osteoclast differentiation
umr04390
Hippo signaling pathway
umr04520
Adherens junction
umr04659
Th17 cell differentiation
umr04926
Relaxin signaling pathway
umr04933
AGE-RAGE signaling pathway in diabetic complications
umr05142
Chagas disease
umr05161
Hepatitis B
umr05166
Human T-cell leukemia virus 1 infection
umr05200
Pathways in cancer
umr05202
Transcriptional misregulation in cancer
umr05210
Colorectal cancer
umr05212
Pancreatic cancer
umr05220
Chronic myeloid leukemia
umr05225
Hepatocellular carcinoma
umr05226
Gastric cancer
umr05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103682015 (TGFBR2)
04350 TGF-beta signaling pathway
103682015 (TGFBR2)
04390 Hippo signaling pathway
103682015 (TGFBR2)
04068 FoxO signaling pathway
103682015 (TGFBR2)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
103682015 (TGFBR2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
103682015 (TGFBR2)
09143 Cell growth and death
04218 Cellular senescence
103682015 (TGFBR2)
09144 Cellular community - eukaryotes
04520 Adherens junction
103682015 (TGFBR2)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
103682015 (TGFBR2)
09152 Endocrine system
04926 Relaxin signaling pathway
103682015 (TGFBR2)
09158 Development and regeneration
04380 Osteoclast differentiation
103682015 (TGFBR2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103682015 (TGFBR2)
05202 Transcriptional misregulation in cancer
103682015 (TGFBR2)
09162 Cancer: specific types
05210 Colorectal cancer
103682015 (TGFBR2)
05212 Pancreatic cancer
103682015 (TGFBR2)
05225 Hepatocellular carcinoma
103682015 (TGFBR2)
05226 Gastric cancer
103682015 (TGFBR2)
05220 Chronic myeloid leukemia
103682015 (TGFBR2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103682015 (TGFBR2)
05161 Hepatitis B
103682015 (TGFBR2)
09174 Infectious disease: parasitic
05142 Chagas disease
103682015 (TGFBR2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
103682015 (TGFBR2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
103682015 (TGFBR2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
umr01001
]
103682015 (TGFBR2)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
103682015 (TGFBR2)
Protein kinases [BR:
umr01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
103682015 (TGFBR2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ecTbetaR2
PK_Tyr_Ser-Thr
Pkinase
ABC1
Haspin_kinase
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
103682015
NCBI-ProteinID:
XP_040492827
UniProt:
A0A8M1GDP9
LinkDB
All DBs
Position
Unknown
AA seq
567 aa
AA seq
DB search
MGRGLLRGLWPLHIVLWTRIASTIPPQVQKSVNNDMMVTDNNGVIKFPQLCKFCDVRSST
CDNQKSCVSNCSITSICEKPHEVCLAVWRKNDENITLETLCHDPKDTYHGIVLEDSASPK
CIMKEKKVLGETFFMCSCSSDECNDYIIFSEEYATNNPDLLLVIFQVTGVSLLPPLGIAI
AVIVTFYCYRVHRQQKLSPSWETSKPRKLMEFSEHLAIILEDDRSDISSTCANNINHNTE
LLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLK
HENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAH
LHSDHTLCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVG
TARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVRE
HPCVESMKDNVLRDRGRPEIPSSWLNHQGIQTVCETLTECWDHDPEARLTAQCVAERFSE
LEHLDRLSGRSCSEEKIPEDGSLNTTK
NT seq
1704 nt
NT seq
+upstream
nt +downstream
nt
atgggtcgggggctgctcaggggcctgtggccgctgcacatcgtcctgtggacgcgcatc
gccagcacgatcccgccgcaagttcagaagtcggttaataatgacatgatggtcaccgac
aacaatggtgtcatcaaatttccacaattgtgtaaattttgcgatgtgagatcttccacc
tgtgacaatcagaaatcctgcgtgagcaactgcagcattacatccatctgtgagaagcca
catgaagtctgtctggcggtctggagaaagaatgatgagaacataacactagagacgctt
tgccatgaccccaaggacacctaccacggaatcgttctcgaagattctgcttctccaaag
tgtattatgaaggaaaaaaaggtgttgggcgagactttctttatgtgttcctgtagctct
gatgagtgcaatgactacatcatcttctcggaagaatatgccaccaacaaccctgacctg
ttgttagtcatattccaagtgacaggcgtcagcctcctgccaccactgggaatcgccata
gccgtcattgtcaccttctactgctaccgggttcaccggcagcagaagctgagcccgtcc
tgggagaccagcaagccgcggaagctcatggagttcagcgagcacctggccatcattctg
gaagacgaccgctccgacatcagctctacctgcgccaacaacatcaaccacaacacagag
ctgctgcccattgagctggacaccctggtggggaaaggtcgcttcgccgaggtctacaag
gccaagctgaagcagaacacttcagaacagttcgagaccgtggcggtcaagatcttccct
tatgaggagtacgcctcctggaagacagagaaggacatcttctcagacatcaacctgaag
catgagaacatcctgcagttcctgacggctgaggagcggaagacagagctggggaagcag
tattggctgatcacagccttccacgccaagggcaacctacaggagtacctcacgcggcac
gtcatcagctgggaggacctgcgcaagctgggcagctccctcgcccggggcattgctcac
ctgcacagtgaccataccctgtgcgggaggcccaagatgcccatcgtgcacagggacctc
aagagctccaatatcctcgtcaagaacgacctgacctgctgcctgtgtgactttgggctt
tccctgcgcctcgacccgactctgtctgtggatgacctggccaacagtgggcaggtggga
accgcaagatacatggctccagaagtcctagagtccaggatgaatctggagaacgttgaa
tcctttaagcagacggatgtctactccatggctctggtactctgggaaatgacatctcgc
tgcaatgcggtgggagaagtgaaagattacgagcctccatttggttccaaggtgcgggag
catccttgtgttgagagcatgaaggacaacgtgctgagagaccgagggcgaccagaaatt
cccagctcctggctcaaccaccagggcatccagacggtgtgcgaaactctgaccgagtgc
tgggaccacgacccggaggcccggctcacggcccagtgcgtggcggagcgcttcagcgaa
ctggagcacctggacaggctctcagggaggagctgctccgaggagaagattcccgaagat
ggctcgctgaacactaccaaatag
DBGET
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