Ursus maritimus (polar bear): 103682015 Help Entry 103682015         CDS       T03271                                  Symbol TGFBR2 Name (RefSeq) TGF-beta receptor type-2   KO K04388   TGF-beta receptor type-2 [EC:2.7.11.30] Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04060   Cytokine-cytokine receptor interaction umr04068   FoxO signaling pathway umr04144   Endocytosis umr04218   Cellular senescence umr04350   TGF-beta signaling pathway umr04380   Osteoclast differentiation umr04390   Hippo signaling pathway umr04520   Adherens junction umr04659   Th17 cell differentiation umr04926   Relaxin signaling pathway umr04933   AGE-RAGE signaling pathway in diabetic complications umr05142   Chagas disease umr05161   Hepatitis B umr05166   Human T-cell leukemia virus 1 infection umr05200   Pathways in cancer umr05202   Transcriptional misregulation in cancer umr05210   Colorectal cancer umr05212   Pancreatic cancer umr05220   Chronic myeloid leukemia umr05225   Hepatocellular carcinoma umr05226   Gastric cancer umr05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103682015 (TGFBR2)    04350 TGF-beta signaling pathway     103682015 (TGFBR2)    04390 Hippo signaling pathway     103682015 (TGFBR2)    04068 FoxO signaling pathway     103682015 (TGFBR2)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     103682015 (TGFBR2)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     103682015 (TGFBR2)   09143 Cell growth and death    04218 Cellular senescence     103682015 (TGFBR2)   09144 Cellular community - eukaryotes    04520 Adherens junction     103682015 (TGFBR2)  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     103682015 (TGFBR2)   09152 Endocrine system    04926 Relaxin signaling pathway     103682015 (TGFBR2)   09158 Development and regeneration    04380 Osteoclast differentiation     103682015 (TGFBR2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103682015 (TGFBR2)    05202 Transcriptional misregulation in cancer     103682015 (TGFBR2)   09162 Cancer: specific types    05210 Colorectal cancer     103682015 (TGFBR2)    05212 Pancreatic cancer     103682015 (TGFBR2)    05225 Hepatocellular carcinoma     103682015 (TGFBR2)    05226 Gastric cancer     103682015 (TGFBR2)    05220 Chronic myeloid leukemia     103682015 (TGFBR2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103682015 (TGFBR2)    05161 Hepatitis B     103682015 (TGFBR2)   09174 Infectious disease: parasitic    05142 Chagas disease     103682015 (TGFBR2)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     103682015 (TGFBR2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     103682015 (TGFBR2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:umr01001]     103682015 (TGFBR2) Enzymes [BR:umr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.30  receptor protein serine/threonine kinase      103682015 (TGFBR2) Protein kinases [BR:umr01001]  Receptor serine/threonine kinases (RSTK): TKL group   TGFBR2 family [OT]    103682015 (TGFBR2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  ecTbetaR2 PK_Tyr_Ser-Thr Pkinase ABC1 Haspin_kinase Pkinase_fungal Motif Other DBs NCBI-GeneID:  103682015 NCBI-ProteinID:  XP_040492827 UniProt:  A0A8M1GDP9 LinkDB All DBs Position Unknown AA seq 567 aa AA seqDB search MGRGLLRGLWPLHIVLWTRIASTIPPQVQKSVNNDMMVTDNNGVIKFPQLCKFCDVRSST CDNQKSCVSNCSITSICEKPHEVCLAVWRKNDENITLETLCHDPKDTYHGIVLEDSASPK CIMKEKKVLGETFFMCSCSSDECNDYIIFSEEYATNNPDLLLVIFQVTGVSLLPPLGIAI AVIVTFYCYRVHRQQKLSPSWETSKPRKLMEFSEHLAIILEDDRSDISSTCANNINHNTE LLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLK HENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAH LHSDHTLCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVG TARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVRE HPCVESMKDNVLRDRGRPEIPSSWLNHQGIQTVCETLTECWDHDPEARLTAQCVAERFSE LEHLDRLSGRSCSEEKIPEDGSLNTTK NT seq 1704 nt NT seq  +upstreamnt  +downstreamnt atgggtcgggggctgctcaggggcctgtggccgctgcacatcgtcctgtggacgcgcatc gccagcacgatcccgccgcaagttcagaagtcggttaataatgacatgatggtcaccgac aacaatggtgtcatcaaatttccacaattgtgtaaattttgcgatgtgagatcttccacc tgtgacaatcagaaatcctgcgtgagcaactgcagcattacatccatctgtgagaagcca catgaagtctgtctggcggtctggagaaagaatgatgagaacataacactagagacgctt tgccatgaccccaaggacacctaccacggaatcgttctcgaagattctgcttctccaaag tgtattatgaaggaaaaaaaggtgttgggcgagactttctttatgtgttcctgtagctct gatgagtgcaatgactacatcatcttctcggaagaatatgccaccaacaaccctgacctg ttgttagtcatattccaagtgacaggcgtcagcctcctgccaccactgggaatcgccata gccgtcattgtcaccttctactgctaccgggttcaccggcagcagaagctgagcccgtcc tgggagaccagcaagccgcggaagctcatggagttcagcgagcacctggccatcattctg gaagacgaccgctccgacatcagctctacctgcgccaacaacatcaaccacaacacagag ctgctgcccattgagctggacaccctggtggggaaaggtcgcttcgccgaggtctacaag gccaagctgaagcagaacacttcagaacagttcgagaccgtggcggtcaagatcttccct tatgaggagtacgcctcctggaagacagagaaggacatcttctcagacatcaacctgaag catgagaacatcctgcagttcctgacggctgaggagcggaagacagagctggggaagcag tattggctgatcacagccttccacgccaagggcaacctacaggagtacctcacgcggcac gtcatcagctgggaggacctgcgcaagctgggcagctccctcgcccggggcattgctcac ctgcacagtgaccataccctgtgcgggaggcccaagatgcccatcgtgcacagggacctc aagagctccaatatcctcgtcaagaacgacctgacctgctgcctgtgtgactttgggctt tccctgcgcctcgacccgactctgtctgtggatgacctggccaacagtgggcaggtggga accgcaagatacatggctccagaagtcctagagtccaggatgaatctggagaacgttgaa tcctttaagcagacggatgtctactccatggctctggtactctgggaaatgacatctcgc tgcaatgcggtgggagaagtgaaagattacgagcctccatttggttccaaggtgcgggag catccttgtgttgagagcatgaaggacaacgtgctgagagaccgagggcgaccagaaatt cccagctcctggctcaaccaccagggcatccagacggtgtgcgaaactctgaccgagtgc tgggaccacgacccggaggcccggctcacggcccagtgcgtggcggagcgcttcagcgaa ctggagcacctggacaggctctcagggaggagctgctccgaggagaagattcccgaagat ggctcgctgaacactaccaaatag

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