Ursus maritimus (polar bear): 103682015
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Entry
103682015 CDS
T03271
Gene name
TGFBR2
Definition
(RefSeq) transforming growth factor beta receptor 2
KO
K04388
TGF-beta receptor type-2 [EC:
2.7.11.30
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr04010
MAPK signaling pathway
umr04060
Cytokine-cytokine receptor interaction
umr04068
FoxO signaling pathway
umr04144
Endocytosis
umr04218
Cellular senescence
umr04350
TGF-beta signaling pathway
umr04380
Osteoclast differentiation
umr04390
Hippo signaling pathway
umr04520
Adherens junction
umr04659
Th17 cell differentiation
umr04926
Relaxin signaling pathway
umr04933
AGE-RAGE signaling pathway in diabetic complications
umr05142
Chagas disease
umr05161
Hepatitis B
umr05166
Human T-cell leukemia virus 1 infection
umr05200
Pathways in cancer
umr05202
Transcriptional misregulation in cancer
umr05210
Colorectal cancer
umr05212
Pancreatic cancer
umr05220
Chronic myeloid leukemia
umr05225
Hepatocellular carcinoma
umr05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103682015 (TGFBR2)
04350 TGF-beta signaling pathway
103682015 (TGFBR2)
04390 Hippo signaling pathway
103682015 (TGFBR2)
04068 FoxO signaling pathway
103682015 (TGFBR2)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
103682015 (TGFBR2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
103682015 (TGFBR2)
09143 Cell growth and death
04218 Cellular senescence
103682015 (TGFBR2)
09144 Cellular community - eukaryotes
04520 Adherens junction
103682015 (TGFBR2)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
103682015 (TGFBR2)
09152 Endocrine system
04926 Relaxin signaling pathway
103682015 (TGFBR2)
09158 Development and regeneration
04380 Osteoclast differentiation
103682015 (TGFBR2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103682015 (TGFBR2)
05202 Transcriptional misregulation in cancer
103682015 (TGFBR2)
09162 Cancer: specific types
05210 Colorectal cancer
103682015 (TGFBR2)
05212 Pancreatic cancer
103682015 (TGFBR2)
05225 Hepatocellular carcinoma
103682015 (TGFBR2)
05226 Gastric cancer
103682015 (TGFBR2)
05220 Chronic myeloid leukemia
103682015 (TGFBR2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
103682015 (TGFBR2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103682015 (TGFBR2)
05161 Hepatitis B
103682015 (TGFBR2)
09174 Infectious disease: parasitic
05142 Chagas disease
103682015 (TGFBR2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
umr01001
]
103682015 (TGFBR2)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
103682015 (TGFBR2)
Protein kinases [BR:
umr01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
103682015 (TGFBR2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ecTbetaR2
PK_Tyr_Ser-Thr
Pkinase
Pkinase_fungal
APH
Motif
Other DBs
NCBI-GeneID:
103682015
NCBI-ProteinID:
XP_008709810
UniProt:
A0A384DSQ3
LinkDB
All DBs
Position
Un
AA seq
644 aa
AA seq
DB search
MPEESMKSRVGDWNNGSLGHFSIYIFCHTGYIRNIKCPTTITLRRLLIDTELRHPQEEAI
PKGRQHSRAHHQCRTSDVLDQNPHFHKVLRWSRRTVKFENENFRTSTYINNDMMVTDNNG
VIKFPQLCKFCDVRSSTCDNQKSCVSNCSITSICEKPHEVCLAVWRKNDENITLETLCHD
PKDTYHGIVLEDSASPKCIMKEKKVLGETFFMCSCSSDECNDYIIFSEEYATNNPDLLLV
IFQVTGVSLLPPLGIAIAVIVTFYCYRVHRQQKLSPSWETSKPRKLMEFSEHLAIILEDD
RSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEE
YASWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVIS
WEDLRKLGSSLARGIAHLHSDHTLCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLR
LDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNA
VGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSSWLNHQGIQTVCETLTECWDH
DPEARLTAQCVAERFSELEHLDRLSGRSCSEEKIPEDGSLNTTK
NT seq
1935 nt
NT seq
+upstream
nt +downstream
nt
atgccagaggaatccatgaagagtcgagtaggtgattggaataatggtagcctcggccac
ttttctatttacattttctgccacactggatacattcgcaacataaaatgtcccaccact
atcactctgcgacggctgctcattgacactgaactgaggcatccccaggaagaggcaatt
ccaaaagggaggcagcactccagagcccatcaccagtgccgcacctccgacgtcctggat
cagaatccgcattttcacaaggtactcaggtggtccagacgcacagtcaagtttgagaac
gaaaacttccggacttcgacctacattaataatgacatgatggtcaccgacaacaatggt
gtcatcaaatttccacaattgtgtaaattttgcgatgtgagatcttccacctgtgacaat
cagaaatcctgcgtgagcaactgcagcattacatccatctgtgagaagccacatgaagtc
tgtctggcggtctggagaaagaatgatgagaacataacactagagacgctttgccatgac
cccaaggacacctaccacggaatcgttctcgaagattctgcttctccaaagtgtattatg
aaggaaaaaaaggtgttgggcgagactttctttatgtgttcctgtagctctgatgagtgc
aatgactacatcatcttctcggaagaatatgccaccaacaaccctgacctgttgttagtc
atattccaagtgacaggcgtcagcctcctgccaccactgggaatcgccatagccgtcatt
gtcaccttctactgctaccgggttcaccggcagcagaagctgagcccgtcctgggagacc
agcaagccgcggaagctcatggagttcagcgagcacctggccatcattctggaagacgac
cgctccgacatcagctctacctgcgccaacaacatcaaccacaacacagagctgctgccc
attgagctggacaccctggtggggaaaggtcgcttcgccgaggtctacaaggccaagctg
aagcagaacacttcagaacagttcgagaccgtggcggtcaagatcttcccttatgaggag
tacgcctcctggaagacagagaaggacatcttctcagacatcaacctgaagcatgagaac
atcctgcagttcctgacggctgaggagcggaagacagagctggggaagcagtattggctg
atcacagccttccacgccaagggcaacctacaggagtacctcacgcggcacgtcatcagc
tgggaggacctgcgcaagctgggcagctccctcgcccggggcattgctcacctgcacagt
gaccataccctgtgcgggaggcccaagatgcccatcgtgcacagggacctcaagagctcc
aatatcctcgtcaagaacgacctgacctgctgcctgtgtgactttgggctttccctgcgc
ctcgacccgactctgtctgtggatgacctggccaacagtgggcaggtgggaaccgcaaga
tacatggctccagaagtcctagagtccaggatgaatctggagaacgttgaatcctttaag
cagacggatgtctactccatggctctggtactctgggaaatgacatctcgctgcaatgcg
gtgggagaagtgaaagattacgagcctccatttggttccaaggtgcgggagcatccttgt
gttgagagcatgaaggacaacgtgctgagagaccgagggcgaccagaaattcccagctcc
tggctcaaccaccagggcatccagacggtgtgcgaaactctgaccgagtgctgggaccac
gacccggaggcccggctcacggcccagtgcgtggcggagcgcttcagcgaactggagcac
ctggacaggctctcagggaggagctgctccgaggagaagattcccgaagatggctcgctg
aacactaccaaatag
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