Vibrio cyclitrophicus: FAZ90_12510
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Entry
FAZ90_12510 CDS
T06393
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
vcc
Vibrio cyclitrophicus
Pathway
vcc00260
Glycine, serine and threonine metabolism
vcc00261
Monobactam biosynthesis
vcc00270
Cysteine and methionine metabolism
vcc00300
Lysine biosynthesis
vcc01100
Metabolic pathways
vcc01110
Biosynthesis of secondary metabolites
vcc01120
Microbial metabolism in diverse environments
vcc01230
Biosynthesis of amino acids
Module
vcc_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
vcc_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
vcc_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
vcc00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
FAZ90_12510 (thrA)
00270 Cysteine and methionine metabolism
FAZ90_12510 (thrA)
00300 Lysine biosynthesis
FAZ90_12510 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
FAZ90_12510 (thrA)
Enzymes [BR:
vcc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
FAZ90_12510 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
FAZ90_12510 (thrA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
QCI71840
LinkDB
All DBs
Position
1:complement(2753816..2756275)
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AA seq
819 aa
AA seq
DB search
MRVLKFGGSSLADADRFLRAADIIANNAQQEELAVVLSAPGKTTNKLVAVIEAALKNGEA
EAQIAEIESSFANLFTEIQAVLPGVDGSAFQEQVYTSLAQLKQFVNGINLLGMCPNHVNA
RIISKGERISIQLMKAVLEAKGQPASLIDPVQYLYAKGDHLEAMVDVDVSTQNFRQSPLP
QGHVNIMPGFTAGNEKGELVTLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYNCDPRLV
HDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFHIPCLIKNSFNPQGAGTLIGQDTG
EDNLAIKGITTLSDLTMVNVSGPGMKGMVGMASRVFGAMSSAGVSIVLITQSSSEYSISF
CIESADKVRAKQVLSEAFELELKDGLLEPVEFMDDVAIVTLVGDGMRTSRGVASQFFSSL
AEVNVNIVAIAQGSSERAISAVIPEDKISEAIKACHENLFNSKHFLDVFVVGVGGVGGEL
VDQIQRQQGKLAEKGIVIRVCGLANSKGLLLDSDGLPLEQWRDRMSSATEEFSLARLAAL
VQRNHIINPVLVDCTSSEGIAAQYADFLAAGFHVVTPNKKANTASMAYYHQLREVARNSR
RKLMYETTVGAGLPVIENLQNLISAGDELEKFNGILSGSLSYIFGKLDEGMTLSQATNIA
KDNGFTEPDPRDDLSGMDVARKLLILAREAGMALELEDVEVDQALPPGFDDSGTVEEFMA
RLPEADAYFKEQSAIAAEEGKVLRYVGEITDGKCKVRIAAVDGDDPMFKIKDGENALAFY
SRYYQPIPLVLRGYGAGTEVTAAGVFSDVMRTLGWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgttttaaaatttggaggttcatcattagctgatgcagatcgttttttacgagcg
gctgatatcatcgctaataatgcccagcaagaagagctagccgttgtactatcggctcca
ggaaaaacaaccaataagctagttgctgttattgaagcggcactaaaaaatggtgaagca
gaagcacaaattgcagaaatcgaatcatcatttgcgaatctgtttacagagattcaggct
gtattaccgggtgttgatggttctgcatttcaagagcaagtgtatacgtctcttgctcaa
ctaaaacagtttgtaaatggcattaacctcttaggtatgtgcccgaatcatgttaatgct
cgtatcatcagtaaaggtgagcgaatctccatccagttaatgaaagcggtacttgaagcg
aaaggccaaccagcaagcctgattgacccagttcagtacttatacgctaaaggtgatcac
cttgaagcgatggttgatgtggatgtttctactcagaacttccgtcaatcaccccttcca
caaggtcacgtaaacatcatgccgggcttcacggccggtaatgaaaaaggtgagttagta
acgcttggtcgtaacggctctgattactcagcagcggttctagcggcgtgtctacgcgcg
gattgttgtgagatctggacagatgtagacggtgtttacaactgtgacccacgtttggtg
catgacgctcgtcttcttaaatcgcttagctaccaagaagcgatggagctttcttatttt
ggtgcttcggttctacatccgaaaactattgctcctatcgcgcaatttcatatcccttgc
ctaatcaaaaacagctttaacccacagggtgcaggtactttgattggtcaagacactggc
gaagataacctagcgatcaaaggcatcacaactcttagtgacctaacgatggttaacgta
tctggccctggtatgaaaggcatggtaggcatggcgagccgtgtgtttggcgcgatgtct
tctgcgggtgtatctattgtccttattactcaatcttcttctgagtacagtatcagcttc
tgtattgaatcggctgataaagtaagagcaaagcaagtgctatcagaggcgtttgaactt
gaattaaaagatggcttgttagagccagtcgagttcatggacgacgtagcgattgttaca
ctggtgggtgacggtatgcgcacatcacgtggtgttgcttctcagttcttctcttcttta
gctgaagtaaatgtcaacattgttgctatcgctcaaggctcatcagaacgcgcgatctct
gcggttatccctgaagataaaatctcagaagcgataaaagcgtgtcacgagaatctattt
aactcgaagcacttccttgacgtattcgttgtcggtgttggtggtgttggcggtgaactt
gttgaccagatccaacgtcaacaaggcaaactggctgagaaaggtattgtgattcgcgtg
tgtggtttagcaaacagcaaaggtttgttgttagacagcgatggtctgccgttagagcaa
tggcgtgatcgtatgtcgagcgcgacagaagagttcagcctagcgcgtttagcggctcta
gttcaacgtaaccacatcatcaaccctgtgttggttgattgtacgtctagcgaaggtatt
gctgctcaatacgcggacttcctagcggctggtttccatgttgtaacaccaaacaaaaaa
gccaacacagcaagcatggcttactaccatcagcttcgtgaagttgcacgtaactctcgt
cgtaagttgatgtacgagacaacagtaggcgcaggtctaccggtaatcgaaaacctacag
aacctaatctctgcaggtgatgagcttgaaaaattcaacggtattctttctggttctctg
tcttacatcttcggtaagcttgatgaaggtatgacacttagccaagcaacaaacattgct
aaagataacggctttactgaacctgatcctcgtgatgacctatctggtatggatgtcgca
cgtaagctgcttattcttgctcgtgaagctggtatggcgcttgagcttgaagacgttgaa
gttgaccaagcattgccaccgggttttgatgattcaggtacggtggaagagtttatggct
cgtttgccagaagcggatgcttatttcaaagagcagtcagctatcgccgcagaagaaggc
aaagtacttcgctatgtcggtgaaatcaccgatggtaagtgtaaagttcgtatcgcagct
gttgatggcgacgacccaatgttcaagattaaagatggcgagaatgcgctggcattctac
agtcgttactaccaaccaatccctcttgtacttcgtggttacggtgcgggtactgaagta
acagcagcaggcgtattctctgatgtgatgcgtactcttggttggaaattaggagtttag
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