Wolbachia endosymbiont of Cimex lectularius: WCLE_005440
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Entry
WCLE_005440 CDS
T03628
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramyl pentapeptide synthase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
wcl
Wolbachia endosymbiont of Cimex lectularius
Pathway
wcl00300
Lysine biosynthesis
wcl00550
Peptidoglycan biosynthesis
wcl01100
Metabolic pathways
wcl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
wcl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
WCLE_005440 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
WCLE_005440 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
WCLE_005440 (murF)
Enzymes [BR:
wcl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
WCLE_005440 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
BetaGal_dom3
Motif
Other DBs
NCBI-ProteinID:
BAO99853
UniProt:
A0A060PYL6
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Position
542607..543983
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AA seq
458 aa
AA seq
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MFKWNASNIIDATGGREVGSCNWVHSSNISTDTRSIKEGDVFIALKGKNFDGHDFLHEAF
LKGAAAAVVSEGKYRNLPLIVVQDTPKALHDIASYYVRNVLVNAKVIAITGSVGKTTTKD
MLHTVLSQYGVSHVNEGNLNNNIGLPLTVLKAPESCQYLILEMGMNKAGEIKELSKISNP
DIAVITNVEPAHVENFSLLLDIAQAKLEVLYGMKNNGTLVLNRDNKYHDYLSSHANRDVI
SFGKDRSATVHLLGLIRDNGGLNLKIRLNNNLIIDCSLPAQGEHFAYSVLAVAAVVQSLG
LDLSKLPFALENFSVTKGRGSVHKAKYNGKNVYLIDDSYNANPASMKAAIRTLGTYSNQR
KVALLGDMLELGNESVAFHTKLLDFIVECGVSKVYTVGKFMLELHRLLPSNIKGTHFNDP
NQLKSDLANIVQNNDVILVKGSRGMKMDLIVQRFIIEY
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgttcaagtggaacgcaagtaatatcatcgatgctactggcggaagagaagtgggtagt
tgtaattgggtacatagctcgaatatttcaacagatacaagaagcataaaagaaggtgat
gtgtttattgcacttaaagggaagaactttgatgggcatgattttttacatgaagcattt
ttaaaaggggcagcagccgcagtagtaagcgaaggcaaatatagaaatcttcctctaatt
gttgtgcaagatactcccaaagctttgcatgatatagcatcatattacgttagaaatgtt
cttgttaatgctaaagttattgcaatcacaggtagtgtcgggaaaaccactacaaaggac
atgctgcacactgttttatcgcaatatggagtgtctcatgtaaacgaagggaacttgaat
aataatataggattgcctttgacagttctgaaagctccggaaagttgccagtacttaatt
cttgaaatggggatgaacaaagctggtgaaataaaagagttatcgaagattagtaatcct
gatatcgcggttatcacaaacgtagaacctgcacatgttgagaatttttcgttgctactt
gatatcgcacaagcaaaattggaagttctgtatggcatgaaaaataacggcactttggtt
ttgaacagagataataaatatcatgactatctctcatcgcatgccaatagagatgtaata
agttttggtaaagatagaagcgctactgtacatttattaggcctaataagagacaatggc
gggctgaatttaaaaattagactgaataataatctgatcatagactgtagtttacctgcg
caaggcgaacattttgcatactctgtgttggctgttgcagcagttgtacaaagtctcgga
cttgatttgtcgaaattaccatttgcacttgagaattttagtgtaaccaaaggtagaggc
agtgttcacaaagctaaatacaatgggaaaaacgtatatttgattgatgattcttataac
gccaatcctgcttcaatgaaagctgcaataaggactttaggtacatattctaatcagagg
aaagtggcactgcttggcgatatgctagaacttggtaatgaaagcgtagcatttcatacg
aagctgcttgattttatcgtagaatgtggtgtgagtaaagtttatacggtcggtaaattt
atgttagaattgcacaggcttttgccaagcaatataaaaggcacgcattttaatgaccct
aatcagttgaaaagtgatttagctaatattgttcagaataatgatgtaattttagtaaaa
ggctcacgtggaatgaaaatggatcttatagtacagagattcataatagaatattaa
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