Xiphophorus maculatus (southern platyfish): 102219526
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Entry
102219526 CDS
T02923
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
xma
Xiphophorus maculatus (southern platyfish)
Pathway
xma00270
Cysteine and methionine metabolism
xma00480
Glutathione metabolism
xma01100
Metabolic pathways
xma01240
Biosynthesis of cofactors
xma04216
Ferroptosis
Module
xma_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
xma00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
102219526 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
102219526 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
102219526 (gclc)
Enzymes [BR:
xma01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
102219526 (gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
102219526
NCBI-ProteinID:
XP_005811935
Ensembl:
ENSXMAG00000010230
UniProt:
M4A732
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Position
22:12481955..12494972
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AA seq
630 aa
AA seq
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MGLLSQGSPLNWEETRKYADHIRKHGIIQFLNIYNKVKDRQRDVLKWGDEVEYMLVELDD
NDEKVRLVLNGGDVLETLQEQGENTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EGNMRKRRLEASSVLKKNMTLCTITSFPRSGCPGFTKPEYRPTPVEKGVSKSLFFPDEAI
NRHPRFSTLTRNIRHRRGEKVVINVPIYKDKHTPSPFVEQFPEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSIDEARYLYDQLATFCPIVMALSAASPFYRGYMSDIDCRWGV
ISASVDDRTQEERGLEPLKNNKYRIFKSRYDSIDSYLSCCGEKYNDIDLTIDEEINKQLL
SAGIDKLLAQHIAHLFIRDPLSVFEEKIYLDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNAV
QEGMFYFRKDMFKGCNPGLDCASSAQNGVEFEGSNEDYTLMSIDTIINGKEGVFQGLIPI
LNSYLENMEVDVDTRCTILNYLKLIKKRASGELMTMAKWMREFVAKHPEYKQDSVITDKI
NYDLLKRCDRIAKGEEQCPELFGNPVNRVK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atggggttactgtcacaaggatctcccctgaactgggaagaaacaaggaagtatgccgac
cacatccgaaagcatggcatcatccagttcctcaacatctacaataaggtcaaggatcgt
cagagagatgtgttgaagtggggtgacgaggttgagtacatgctggtggagctggatgac
aatgatgagaaggttcgactggtgctgaatggtggagatgttttggaaactctccaagaa
cagggagaaaatacaaacccgaatcatccaacactttggagaccagagtatggcagctac
atgatcgagggaacgcctgggcagccgtacgggggaaccatgtcagagttcaacacggtg
gagggcaacatgaggaagagacgtctggaggcttcgtctgtcctgaagaagaatatgacg
ctctgcaccatcacctcctttccaaggtcaggttgtccaggtttcaccaaaccagagtac
cgacccactcccgttgaaaagggagtgtcaaagtctttgtttttcccagatgaagccata
aacagacaccccagattcagcactctgaccagaaacatacgccatcgaagaggagagaaa
gttgtgataaatgtgccaatctacaaagataagcacacaccgtcaccatttgtggagcag
ttccctgaggatgacggcgaagcagcgagggcagcccttcctgaccacatctatatggac
gccatgggcttcggcatgggcaactgctgcctgcaagtgacattccaagcttgcagcatt
gatgaggcaaggtatctttatgaccaactagcaacattctgccccattgtgatggcactg
agtgctgcctcacccttctacagagggtacatgtctgatattgattgtcgctggggagtt
atctcagcctcagtggatgacaggacccaagaggaacgaggcctggagcctctgaagaac
aacaagtacaggatctttaagtccaggtatgactcgattgacagctacctgtcttgctgt
ggagagaagtacaatgacatcgatttgacgatagatgaggagatcaacaagcagctgctc
agtgcagggattgacaagcttctggctcaacacatagctcacctcttcatacgagacccg
ctctctgtctttgaggagaaaatatatttggatgatgaaaacgaatcggatcactttgag
aatcttcagtcgaccaactggcagacgatgaggttcaaacctccacctccgaactccgac
atcggctggagagttgagtttcgccccatggaggttcagctaactgactttgaaaatgct
gcatatgtggtttttgttgtcctgcttaccagagtgatcttatcctacaagctggatttc
ctaatccccttatcaaaggtggatgagaacatgaaggtggcgcagaagagaaacgcagtc
caggagggcatgttttatttccgcaaagacatgtttaaaggctgcaacccaggcttggac
tgtgcttcttctgctcagaatggcgtagagtttgagggcagtaacgaggattacacactg
atgagcatcgacacaatcatcaacgggaaggagggagtatttcaaggccttatcccaatc
cttaactcctatctggaaaacatggaagttgatgttgacaccaggtgcactattttgaat
tatctgaagctcatcaagaaacgtgcctcgggagaactgatgaccatggccaagtggatg
agggaatttgttgcaaaacaccctgagtacaagcaggacagtgtcattactgacaagatc
aactacgacctgctcaaaaggtgcgacaggattgctaaaggcgaagagcagtgccccgag
ctttttggtaacccagtcaaccgagtgaagtga
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