Zalophus californianus (California sea lion): 113921975
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Entry
113921975 CDS
T07874
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca01522
Endocrine resistance
zca04010
MAPK signaling pathway
zca04015
Rap1 signaling pathway
zca04068
FoxO signaling pathway
zca04071
Sphingolipid signaling pathway
zca04114
Oocyte meiosis
zca04148
Efferocytosis
zca04218
Cellular senescence
zca04261
Adrenergic signaling in cardiomyocytes
zca04370
VEGF signaling pathway
zca04380
Osteoclast differentiation
zca04550
Signaling pathways regulating pluripotency of stem cells
zca04611
Platelet activation
zca04613
Neutrophil extracellular trap formation
zca04620
Toll-like receptor signaling pathway
zca04621
NOD-like receptor signaling pathway
zca04622
RIG-I-like receptor signaling pathway
zca04625
C-type lectin receptor signaling pathway
zca04657
IL-17 signaling pathway
zca04658
Th1 and Th2 cell differentiation
zca04659
Th17 cell differentiation
zca04660
T cell receptor signaling pathway
zca04664
Fc epsilon RI signaling pathway
zca04668
TNF signaling pathway
zca04670
Leukocyte transendothelial migration
zca04714
Thermogenesis
zca04722
Neurotrophin signaling pathway
zca04723
Retrograde endocannabinoid signaling
zca04728
Dopaminergic synapse
zca04750
Inflammatory mediator regulation of TRP channels
zca04912
GnRH signaling pathway
zca04914
Progesterone-mediated oocyte maturation
zca04917
Prolactin signaling pathway
zca04926
Relaxin signaling pathway
zca04932
Non-alcoholic fatty liver disease
zca04933
AGE-RAGE signaling pathway in diabetic complications
zca04935
Growth hormone synthesis, secretion and action
zca04936
Alcoholic liver disease
zca05014
Amyotrophic lateral sclerosis
zca05020
Prion disease
zca05022
Pathways of neurodegeneration - multiple diseases
zca05132
Salmonella infection
zca05133
Pertussis
zca05135
Yersinia infection
zca05140
Leishmaniasis
zca05142
Chagas disease
zca05145
Toxoplasmosis
zca05152
Tuberculosis
zca05161
Hepatitis B
zca05163
Human cytomegalovirus infection
zca05167
Kaposi sarcoma-associated herpesvirus infection
zca05169
Epstein-Barr virus infection
zca05170
Human immunodeficiency virus 1 infection
zca05171
Coronavirus disease - COVID-19
zca05205
Proteoglycans in cancer
zca05208
Chemical carcinogenesis - reactive oxygen species
zca05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
zca05415
Diabetic cardiomyopathy
zca05417
Lipid and atherosclerosis
zca05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
113921975 (MAPK12)
04015 Rap1 signaling pathway
113921975 (MAPK12)
04370 VEGF signaling pathway
113921975 (MAPK12)
04668 TNF signaling pathway
113921975 (MAPK12)
04068 FoxO signaling pathway
113921975 (MAPK12)
04071 Sphingolipid signaling pathway
113921975 (MAPK12)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
113921975 (MAPK12)
09143 Cell growth and death
04114 Oocyte meiosis
113921975 (MAPK12)
04218 Cellular senescence
113921975 (MAPK12)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
113921975 (MAPK12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
113921975 (MAPK12)
04613 Neutrophil extracellular trap formation
113921975 (MAPK12)
04620 Toll-like receptor signaling pathway
113921975 (MAPK12)
04621 NOD-like receptor signaling pathway
113921975 (MAPK12)
04622 RIG-I-like receptor signaling pathway
113921975 (MAPK12)
04625 C-type lectin receptor signaling pathway
113921975 (MAPK12)
04660 T cell receptor signaling pathway
113921975 (MAPK12)
04658 Th1 and Th2 cell differentiation
113921975 (MAPK12)
04659 Th17 cell differentiation
113921975 (MAPK12)
04657 IL-17 signaling pathway
113921975 (MAPK12)
04664 Fc epsilon RI signaling pathway
113921975 (MAPK12)
04670 Leukocyte transendothelial migration
113921975 (MAPK12)
09152 Endocrine system
04912 GnRH signaling pathway
113921975 (MAPK12)
04914 Progesterone-mediated oocyte maturation
113921975 (MAPK12)
04917 Prolactin signaling pathway
113921975 (MAPK12)
04926 Relaxin signaling pathway
113921975 (MAPK12)
04935 Growth hormone synthesis, secretion and action
113921975 (MAPK12)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
113921975 (MAPK12)
09156 Nervous system
04728 Dopaminergic synapse
113921975 (MAPK12)
04723 Retrograde endocannabinoid signaling
113921975 (MAPK12)
04722 Neurotrophin signaling pathway
113921975 (MAPK12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
113921975 (MAPK12)
09158 Development and regeneration
04380 Osteoclast differentiation
113921975 (MAPK12)
09159 Environmental adaptation
04714 Thermogenesis
113921975 (MAPK12)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
113921975 (MAPK12)
05208 Chemical carcinogenesis - reactive oxygen species
113921975 (MAPK12)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
113921975 (MAPK12)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
113921975 (MAPK12)
05161 Hepatitis B
113921975 (MAPK12)
05171 Coronavirus disease - COVID-19
113921975 (MAPK12)
05163 Human cytomegalovirus infection
113921975 (MAPK12)
05167 Kaposi sarcoma-associated herpesvirus infection
113921975 (MAPK12)
05169 Epstein-Barr virus infection
113921975 (MAPK12)
09171 Infectious disease: bacterial
05132 Salmonella infection
113921975 (MAPK12)
05135 Yersinia infection
113921975 (MAPK12)
05133 Pertussis
113921975 (MAPK12)
05152 Tuberculosis
113921975 (MAPK12)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
113921975 (MAPK12)
05140 Leishmaniasis
113921975 (MAPK12)
05142 Chagas disease
113921975 (MAPK12)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
113921975 (MAPK12)
05020 Prion disease
113921975 (MAPK12)
05022 Pathways of neurodegeneration - multiple diseases
113921975 (MAPK12)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
113921975 (MAPK12)
05418 Fluid shear stress and atherosclerosis
113921975 (MAPK12)
05415 Diabetic cardiomyopathy
113921975 (MAPK12)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
113921975 (MAPK12)
04932 Non-alcoholic fatty liver disease
113921975 (MAPK12)
04933 AGE-RAGE signaling pathway in diabetic complications
113921975 (MAPK12)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
113921975 (MAPK12)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
zca01001
]
113921975 (MAPK12)
Enzymes [BR:
zca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
113921975 (MAPK12)
Protein kinases [BR:
zca01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
113921975 (MAPK12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
113921975
NCBI-ProteinID:
XP_027449362
EnsemblRapid:
ENSZCAG00025010257
UniProt:
A0A6J2D3A2
LinkDB
All DBs
Position
9:479296..488176
Genome browser
AA seq
389 aa
AA seq
DB search
MSSPPPARRGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDLPPRTQGGDTAGWSWR
CERGTACYLVMPFMGTDLGKLMKHEKLSEDRIQFLVYQMLKGLKYIHAAGIIHRDLKPGN
LAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSAGCIMAE
MITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSADAKNYMKGLPELEKKDFASILT
NASPLAVNLLEKMLVLDAERRVTAAEALTHPYFESLQDTEDEPKAQKYDESFDDMDRTLD
EWKRVTYKEVLSFKPPRQLGTKVSKETAL
NT seq
1170 nt
NT seq
+upstream
nt +downstream
nt
atgagctctccaccgcccgcccgcaggggcttttaccgccaggaggtgaccaagacggct
tgggaggtgcgcgccgtgtaccaggacctgcagcccgtgggctccggcgcctacggcgcg
gtgtgctcggccgtggacagccgcactggcgccaaggtggccatcaagaaactgtaccgg
cccttccagtcggagctcttcgccaagcgcgcctaccgcgaactgcgcctcctcaagcac
atgcgccacgagaacgtcatcgggctgctggacgtgttcacccctgatgaaaccctggat
gatttcacagacttgcccccccggacccagggtggtgacacagccgggtggagctggagg
tgtgagcgcgggactgcatgttacctggtgatgccgttcatggggactgacctgggcaag
ctcatgaagcatgagaagctgagtgaggaccgaatccagttccttgtctaccagatgctg
aaggggctaaagtacatccatgctgctggcatcatccatagggacctgaagcccggcaat
ctggcagtgaatgaggactgtgagctgaagatcctggacttcggcctggcgaggcaggca
gacagcgagatgactgggtatgtggtgactcggtggtaccgggcacctgaggtcatcttg
aattggatgcgctacacgcagacagtggatatctggtcggcgggctgcatcatggcggag
atgattacagggaagacgctgttcaagggcagtgaccacctggaccagctgaaggagatc
atgaaggtgacagggacgcctcccgctgagtttgtgcagaggctgcagagtgccgatgcg
aagaactacatgaagggcctccccgagttggagaagaaggatttcgcatccatcctgact
aatgcaagtcctctggctgtgaacctcctggagaaaatgcttgtgctagatgcagagcgg
cgggtgactgcggccgaggcgctgacccacccctacttcgagtcactgcaggacacggag
gatgagcccaaggcccagaagtacgacgagtcctttgatgatatggaccgcacgctggat
gagtggaaacgtgtcacatataaagaagtgctcagcttcaagcctccccggcagctgggg
accaaggtctccaaggagacggccctgtga
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