KEGG   ENZYME: 1.1.1.341
Entry
EC 1.1.1.341                Enzyme                                 
Name
CDP-abequose synthase;
rfbJ (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
CDP-alpha-D-abequose:NADP+ 4-oxidoreductase
Reaction(IUBMB)
CDP-alpha-D-abequose + NADP+ = CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H+ [RN:R08711]
Reaction(KEGG)
R08711
Substrate
CDP-alpha-D-abequose [CPD:C01788];
NADP+ [CPD:C00006]
Product
CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose [CPD:C04297];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Isolated from Yersinia pseudotuberculosis [1,3] and Salmonella enterica [1,2].
History
EC 1.1.1.341 created 2012
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
ec00541  O-Antigen nucleotide sugar biosynthesis
ec01100  Metabolic pathways
Orthology
K12455  CDP-abequose synthase
K19632  CDP-abequose synthase
Genes
STM: STM2089(rfbJ)
SEO: STM14_2583(rfbJ)
SEV: STMMW_21201
SEY: SL1344_2066(rfbJ)
SEM: STMDT12_C21110
SEJ: STMUK_2119(rfbJ)
SEB: STM474_2174(rfbJ)
SEF: UMN798_2257(rfbJ)
SETU: STU288_06830
SETC: CFSAN001921_06335
SENR: STMDT2_20631
SEND: DT104_21481
SEEN: SE451236_16655
SPQ: SPAB_00941
SEH: SeHA_C2315
SHB: SU5_02683
SENH: CFSAN002069_21375
SEEH: SEEH1578_19725
SEW: SeSA_A2322
SEA: SeAg_B2214
SENS: Q786_10315
CIX: M4I31_08875(rfbJ)
YPQ: DJ40_1357
YPR: BZ20_1044
PAKH: B0X70_24655
PLUI: CE143_24695
SKH: STH12_02109(rfbJ)
SAVI: JYB87_13140
TCAR: U0034_20320
MPAU: ZMTM_15440(prt)
AOZ: HUE56_00360
AZS: E6C72_31025
CINF: CINF_0710
PIJ: QEJ31_04365
BPAB: PSE45_08665
BREH: HP435_09235
PLUT: EI981_25810
PMAE: LMZ02_01930
LFS: HFV01_27460
DRC: G0Q07_02765
SABU: MBM09_01935
PROW: OO006_02870
 » show all
Reference
1  [PMID:1724263]
  Authors
Kessler AC, Brown PK, Romana LK, Reeves PR
  Title
Molecular cloning and genetic characterization of the rfb region from Yersinia pseudotuberculosis serogroup IIA, which determines the formation of the 3,6-dideoxyhexose abequose.
  Journal
J Gen Microbiol 137:2689-95 (1991)
DOI:10.1099/00221287-137-12-2689
  Sequence
[ag:AAB49402]
Reference
2  [PMID:2793832]
  Authors
Wyk P, Reeves P
  Title
Identification and sequence of the gene for abequose synthase, which confers antigenic specificity on group B salmonellae: homology with galactose epimerase.
  Journal
J Bacteriol 171:5687-93 (1989)
DOI:10.1128/JB.171.10.5687-5693.1989
  Sequence
[stm:STM2089]
Reference
3  [PMID:8071227]
  Authors
Thorson JS, Lo SF, Ploux O, He X, Liu HW
  Title
Studies of the biosynthesis of 3,6-dideoxyhexoses: molecular cloning and characterization of the asc (ascarylose) region from Yersinia pseudotuberculosis serogroup VA.
  Journal
J Bacteriol 176:5483-93 (1994)
DOI:10.1128/JB.176.17.5483-5493.1994
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.341
IUBMB Enzyme Nomenclature: 1.1.1.341
ExPASy - ENZYME nomenclature database: 1.1.1.341
BRENDA, the Enzyme Database: 1.1.1.341
LinkDB

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