KEGG   ENZYME: 1.1.1.341
Entry
EC 1.1.1.341                Enzyme                                 
Name
CDP-abequose synthase;
rfbJ (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
CDP-alpha-D-abequose:NADP+ 4-oxidoreductase
Reaction(IUBMB)
CDP-alpha-D-abequose + NADP+ = CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H+ [RN:R08711]
Reaction(KEGG)
R08711
Substrate
CDP-alpha-D-abequose [CPD:C01788];
NADP+ [CPD:C00006]
Product
CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose [CPD:C04297];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Isolated from Yersinia pseudotuberculosis [1,3] and Salmonella enterica [1,2].
History
EC 1.1.1.341 created 2012
Pathway
ec00541  Biosynthesis of various nucleotide sugars
ec01100  Metabolic pathways
Orthology
K12455  CDP-abequose synthase
K19632  CDP-abequose synthase
Genes
STM: STM2089(rfbJ)
SEO: STM14_2583(rfbJ)
SEV: STMMW_21201
SEY: SL1344_2066(rfbJ)
SEM: STMDT12_C21110
SEJ: STMUK_2119(rfbJ)
SEB: STM474_2174(rfbJ)
SEF: UMN798_2257(rfbJ)
SETU: STU288_06830
SETC: CFSAN001921_06335
SENR: STMDT2_20631
SEND: DT104_21481
SEEN: SE451236_16655
SPQ: SPAB_00941
SEH: SeHA_C2315
SHB: SU5_02683
SENH: CFSAN002069_21375
SEEH: SEEH1578_19725
SEE: SNSL254_A2271
SENN: SN31241_31950
SEW: SeSA_A2322
SEA: SeAg_B2214
SENS: Q786_10315
SENB: BN855_21780
SALZ: EOS98_08530
ECHU: RQP59_15595
CIX: M4I31_08875(rfbJ)
KIE: NCTC12125_00628(rfbB_2)
MPHG: MPHASIOC01_002282
YPQ: DJ40_1357
YPR: BZ20_1044
PAKH: B0X70_24655
PLUI: CE143_24695
SAVI: JYB87_13140
PFIB: PI93_023525
BREP: M655_018850
BGEL: AAFJ72_07010
 » show all
Reference
1  [PMID:1724263]
  Authors
Kessler AC, Brown PK, Romana LK, Reeves PR
  Title
Molecular cloning and genetic characterization of the rfb region from Yersinia pseudotuberculosis serogroup IIA, which determines the formation of the 3,6-dideoxyhexose abequose.
  Journal
J Gen Microbiol 137:2689-95 (1991)
DOI:10.1099/00221287-137-12-2689
  Sequence
[ag:AAB49402]
Reference
2  [PMID:2793832]
  Authors
Wyk P, Reeves P
  Title
Identification and sequence of the gene for abequose synthase, which confers antigenic specificity on group B salmonellae: homology with galactose epimerase.
  Journal
J Bacteriol 171:5687-93 (1989)
DOI:10.1128/JB.171.10.5687-5693.1989
  Sequence
[stm:STM2089]
Reference
3  [PMID:8071227]
  Authors
Thorson JS, Lo SF, Ploux O, He X, Liu HW
  Title
Studies of the biosynthesis of 3,6-dideoxyhexoses: molecular cloning and characterization of the asc (ascarylose) region from Yersinia pseudotuberculosis serogroup VA.
  Journal
J Bacteriol 176:5483-93 (1994)
DOI:10.1128/JB.176.17.5483-5493.1994
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.341
IUBMB Enzyme Nomenclature: 1.1.1.341
ExPASy - ENZYME nomenclature database: 1.1.1.341
BRENDA, the Enzyme Database: 1.1.1.341
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