KEGG   ENZYME: 1.1.1.377
Entry
EC 1.1.1.377                Enzyme                                 
Name
L-rhamnose 1-dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
L-rhamnose:NADP+ 1-oxidoreductase
Reaction(IUBMB)
L-rhamnose + NADP+ = L-rhamnono-1,4-lactone + NADPH + H+ [RN:R10788]
Reaction(KEGG)
R10788
Substrate
L-rhamnose [CPD:C00507];
NADP+ [CPD:C00006]
Product
L-rhamnono-1,4-lactone [CPD:C02991];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme from the archaeon Thermoplasma acidophilum is part of the non-phosphorylative degradation pathway for L-rhamnose. The enzyme differs in cofactor specificity from EC 1.1.1.173, L-rhamnose 1-dehydrogenase, which is specific for NAD+.
History
EC 1.1.1.377 created 2014
Pathway
ec00051  Fructose and mannose metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K18337  L-rhamnose 1-dehydrogenase
Genes
DHADEHA2E01100g
PICPICST_50944(DHG2)
PGUPGUG_03591
CTEN18247188(DHG2)
CLUCLUG_02926
CLUSA9F13_18g00385
PPAPAS_chr4_0338
BNNFOA43_001971(DHG2)
OPAHPODL_01987
SLBAWJ20_4952(SPS19)
NCRNCU09035
NTENEUTE1DRAFT102514(NEUTE1DRAFT_102514)
SMP10803051(SMAC4_05850)
PANPODANSg706
PBELQC761_400940
PPSDQC762_400940
PPSPQC763_400940
PPSAQC764_400940
TTTTHITE_2111000
MTMMYCTH_102290
CTHRCTHT_0045640
MGRMGG_08318
PPEIPpBr36_02105
PGRIPgNI_07905
TMNUCRPA7_3732 UCRPA7_5029
SSCKSPSK_02647
FGRFGSG_09882
FPUFPSE_10199
FPOAFPOAC1_002961
FVNFVRRES_03279
FVRFVEG_02597
FOXFOXG_05543
NHENECHADRAFT_37021 NECHADRAFT_41350
FFCNCS54_00676000
FKRNCS57_00469700 NCS57_00715800
FMUJ7337_005520
TRETRIREDRAFT_65588
TRRM419DRAFT_36736
TATV25775150(TrAtP1_001151)
TASP36615895(DHG2)
MAJMAA_08254
MBRN26246537(DHG2)
PCHMVFPPC_07453
CMTCCM_06363
AMUSLMH87_000967 LMH87_002840
PLJ28891680(PLICBS_010274)
PTKZJDV02_002154(DHG2)
VALVDBG_07058
VDAVDAG_06700
CFJCFIO01_07064 CFIO01_09199
CLUPCLUP02_17412
CHIGCH63R_09431
CDET87949276(CDEST_12776) 87950630(CDEST_14130)
ELAUCREL1_2272 UCREL1_7808
PFYPFICI_03100 PFICI_06510 PFICI_13970
SSLSS1G_10326
BFUBCIN_14g04170
MBEMBM_02654
PSCOLY89DRAFT_684259 LY89DRAFT_707448
GLZGLAREA_03301
ANIANIA_01886 ANIA_04186
AFMAFUA_7G04360
ACTACLA_006060
NFINFIA_025330
AORAO090005000123
ANGAn05g02050 An13g00930
AFVAFLA_002906
ALUCAKAW2_20117A(DHG2) AKAW2_81349A
ACHEACHE_31306A ACHE_40186A(DHG2)
APUUAPUU_21191A APUU_50081S APUU_60465A(DHG2) APUU_60792A
PCSN7525_005303 N7525_006925
PDPPDIP_82370
POUPOX_b03426
TMFEYB26_005568
TRGTRUGW13939_06749 TRUGW13939_09624
ABEARB_00929
TVETRV_00758
PNOSNOG_14192(SNOG_14191)
PTEPTT_09742
PTRR6342727(PtrM4_114020)
BZECOCCADRAFT_36707
BSCCOCSADRAFT_40878
BORCOCMIDRAFT_4863
AALTCC77DRAFT_1054497
ARABEKO05_0003752
ZTRMYCGRDRAFT_83548
PFJMYCFIDRAFT_39072
FFUCLAFUR5_12021 CLAFUR5_13485
CBETCB0940_06284 CB0940_11605
BCOMBAUCODRAFT_64509
NPAUCRNP2_3170
TMLGSTUM_00003021001 GSTUM_00009300001
CNECNB05760
CNBCNBB0030
CNGCNAG_04097
CGICGB_A0020C
CDEUCNBG_5386
CDEP91085938(L203_101725)
KMG30165237(I203_108529)
KNE92177317(IAR55_000057)
TASAA1Q1_01844
CCACCcaHIS019_0607430(DHG2)
PPLPOSPLDRAFT_87849
TVSTRAVEDRAFT_159063
DSQDICSQDRAFT_131032
PCOPHACADRAFT_247452
SHSSTEHIDRAFT_89569
HIRHETIRDRAFT_456869
PSQPUNSTDRAFT_48714
ADLAURDEDRAFT_80943
FMEFOMMEDRAFT_81776
GTRGLOTRDRAFT_53059
RSXRhiXN_00566
ABPAGABI1DRAFT31987(AGABI1DRAFT_31987)
ABVAGABI2DRAFT182285(AGABI2DRAFT_182285)
MPRMPER_11191
MRRMoror_17215
MOREE1B28_000966
SCMSCHCO_02610587(SCHCODRAFT_02610587)
CPUTCONPUDRAFT_86700
SLASERLADRAFT_467003
UMAUMAG_11693
PFPPFL1_03743
SGRAEX895_004391
PFNHZ99_04550
PTVAA957_01200
PAZOAYR47_21440
PBREQDY63_16900
PFXA7318_11935
PYMAK972_2741
PEZHWQ56_16160
PTRTHU722_0013875
AVNAvin_09160
AVLAvCA_09160
AVDAvCA6_09160
ABERBSR55_00550
HELHELO_4213(rhaD)
HHUAR456_20000
HBHE4T21_09965
HHAOQWG60_05015
COBBH2O77_06785
COBDU0O11_06430
SALNSALB1_2836
AMAHDLM_0709
AQSDKK66_01665
BCMBcenmc03_6233
BCHBcen2424_6635
BAMBamb_3400
BACBamMC406_1208
BPYRABD05_31635
BSEMWJ12_16075
BUGBC1001_3863
BGFBC1003_5545
BYIBYI23_B007530
BUEBRPE67_BCDS10610
BUQAC233_21650
BGPBGL_2c06950(fabG4)
BPLAbpln_2g07800
BUMAXG89_17635
BUIAX768_27415
BURKDM992_37155
BXEBxe_B1031
BXBDR64_6352
BPHBphy_3467
BGEBC1002_4237
BPXBUPH_00437
BPYBphyt_5688
BFNOI25_6825
BCAIK788_0008513
PSPWBJG93_25610
PARABTO02_31830
PARBCJU94_23860
PHSC2L64_22530
PTERC2L65_25100
PGPCUJ91_21880
PCJCUJ87_23065
PTSCUJ90_29530
PMEGFNZ07_09785
PTROG5S35_23015
PGISI6I06_24295
PACPFAZ97_21155
PACSFAZ98_17345
PEWKZJ38_34630
PDIOPDMSB3_2081.1(rhaD)
PBRYNDK50_27200
PSAAQEN71_12635
PKFRW095_19230
PHUNU0042_07615
PLADPPGU16_41630
CABASBC2_60260
BUOBRPE64_BCDS05710
CABKNK8_34400
TVLFAZ95_33600
TCARU0034_23330
VPDVAPA_2c00520
MESPC1M53_17345
RPODE0E05_15250
CSECseg_1768 Cseg_2740
CFHC1707_14155
BSBBresu_2867
BRDJL11_06990
BRGA4249_07690
BREVE7T10_08375
BNDKWG56_07380
BFQJX001_09280
BRESE4341_07345
AEXAstex_2133
ASTIQ1W73_03000
ASTDATDW_19930
PTPRCA23_c23450(fabG4)
HBAHbal_2755
STAXMC45_07230 MC45_07285
SPHITS85_02230
SSANNX02_22785
SNJA7E77_11680
SMYBJP26_16645
SPANAWL63_05960
SKRBRX40_01540
SPLMBXU08_17995
SPHCCVN68_10795
SARIH5J25_00325
SSUAFPZ54_00310
SBINSBA_ch1_06520
SCABLZK98_19645
SNOSK8P63_02120
SSAGKV697_00800
SABIPBT88_17560
SPHRBSY17_3168
SYAA6768_21720
SPYGYGS_C1P2522
SPAGsphantq_01941(fabG_2)
SPCAGL174_11605
BLASBSY18_1707
BFWB5J99_17915
SSAARPR59_02250
SPHSETR14_07025
ALTNLBX01_05115
TFVIDJ81_03365
ABGAsbog_01342
ROSCTJ15_21290
NAOY958_05065
NCBC0V82_24320
PPSCEHS13_31275
PBKBack11_16610(fabG_2)
CHEBHH215_02220 HH215_18270
COHLJ4772_13335 J4772_23225
PMADBAY61_19440
ATLAthai_30200
ASERAsera_44360
SACISinac_3785
CPOLWJU16_05740
CHIMCK934_14605
RCGN7E81_02085
TACTa0747
TVOTVG0436799(TVG0436799)
FACFACI_IFERC01G0497
 » show all
Reference
1  [PMID:22481639]
  Authors
Kim SM, Paek KH, Lee SB
  Title
Characterization of NADP+-specific L-rhamnose dehydrogenase from the thermoacidophilic Archaeon Thermoplasma acidophilum.
  Journal
Extremophiles 16:447-54 (2012)
DOI:10.1007/s00792-012-0444-1
  Sequence
[tac:Ta0747]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.377
IUBMB Enzyme Nomenclature: 1.1.1.377
ExPASy - ENZYME nomenclature database: 1.1.1.377
BRENDA, the Enzyme Database: 1.1.1.377
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