Entry Name D-mannitol oxidase;
Class Oxidoreductases;BRITE hierarchy
Sysname mannitol:oxygen oxidoreductase (cyclizing)
Reaction(IUBMB) D-mannitol + O2 = D-mannose + H2O2 [RN:
R05698 ]
Reaction(KEGG) Substrate Product Comment Also catalyses the oxidation of D-arabinitol and, to a lesser extent, D-glucitol (sorbitol), whereas L-arabinitol is not a good substrate. The enzyme from the snails Helix aspersa and Arion ater is found in a specialised tubular organelle that has been termed the mannosome.
History EC 1.1.3.40 created 2001
Reference Authors Vorhaben JE, Smith DD Jr, Campbell JW.
Title Mannitol oxidase: partial purification and characterization of the membrane-bound enzyme from the snail Helix aspersa.
Journal Reference 2
Authors Malik Z, Jones CJP, Connock MJ.
Title Assay and subcellular localization of H2O2 generating mannitol oxidase in the terrestrial slug Arion ater.
Journal J Exp Zool 242:9-15 (1987)
Reference 3
Authors Large AT, Jones CJP, Connock MJ.
Title The association of mannitol oxidase with a distinct organelle in the digestive gland of the terrestrial slug Arion ater.
Journal Protoplasma 175:93-101 (1993)
Reference Authors Lobo-da-Cunha A, Amaral-de-Carvalho D, Oliveira E, Alves A, Costa V, Calado G
Title Mannitol oxidase and polyol dehydrogenases in the digestive gland of gastropods: Correlations with phylogeny and diet.
Journal Other DBs ExplorEnz - The Enzyme Database: 1.1.3.40
ExPASy - ENZYME nomenclature database: 1.1.3.40
LinkDB All DBs
