KEGG   ENZYME: 1.1.98.2
Entry
EC 1.1.98.2                 Enzyme                                 
Name
glucose-6-phosphate dehydrogenase (coenzyme-F420);
coenzyme F420-dependent glucose-6-phosphate dehydrogenase;
F420-dependent glucose-6-phosphate dehydrogenase;
FGD1;
Rv0407;
F420-dependent glucose-6-phosphate dehydrogenase 1
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With other, known, physiological acceptors
Sysname
D-glucose-6-phosphate:F420 1-oxidoreductase
Reaction(IUBMB)
D-glucose 6-phosphate + oxidized coenzyme F420 = 6-phospho-D-glucono-1,5-lactone + reduced coenzyme F420 [RN:R09550]
Reaction(KEGG)
R09550
Substrate
D-glucose 6-phosphate [CPD:C00092];
oxidized coenzyme F420 [CPD:C00876]
Product
6-phospho-D-glucono-1,5-lactone [CPD:C01236];
reduced coenzyme F420 [CPD:C01080]
Comment
The enzyme is very specific for D-glucose 6-phosphate. No activity with NAD+, NADP+, FAD and FMN [1].
History
EC 1.1.98.2 created 2010 as EC 1.1.99.34, transferred 2011 to EC 1.1.98.2
Orthology
K15510  coenzyme F420-dependent glucose-6-phosphate dehydrogenase
Genes
STARG3545_06910(fgd)
APRAG3A50_17770(fgd)
MOGMMB17_16640(fgd)
METGHT051_05395(fgd)
PHLKKY_221
PEMOF122_17160
DEIC4375_12610(fgd)
DEAFPZ08_05340(fgd)
DSALK1X15_15285(fgd)
DEVOH4N61_13625(fgd)
DNPN8A98_18060(fgd)
DOYJI749_11420(fgd)
DRHJI748_01620(fgd)
KHAIFJ82_10845(fgd)
MTURv0407(fgd1)
MTVRVBD_0407
MTCMT0420(fgd)
MRAMRA_0413(fgd1)
MTFTBFG_10412
MTBTBMG_00408
MTKTBSG_00411
MTZTBXG_000406
MTIMRGA423_02565
MTECCDC5079_0381
MTURCFBS_0423(fgd1)
MTLCCDC5180_0376
MTOMTCTRI2_0410(fgd1)
MTDUDA_0407(fgd1)
MTNERDMAN_0449(fgd1)
MTJJ112_02170
MTUBMT7199_0414
MTUEJ114_02165
MTXM943_02110
MTULTBHG_00403
MTUTHKBT1_0423(fgd1)
MTUUHKBT2_0423(fgd1)
MTQHKBS1_0423(fgd1)
MBOBQ2027_MB0415(fgd1)
MBBBCG_0446(fgd1)
MBTJTY_0416(fgd1)
MBMBCGMEX_0417(fgd1)
MBKK60_004300
MBXBCGT_0178
MAFMAF_04090(fgd1)
MMICRN08_0458
MCEMCAN_04051(fgd1)
MCQBN44_10448(fgd)
MCVBN43_10440(fgd)
MCXBN42_20128(fgd)
MCZBN45_10445(fgd)
MORYMO_000430(fgd)
MLEML0269
MLBMLBr00269
MPAMAP_3884
MAOMAP4_3999
MAVIRC58_19860
MAVURE97_19915
MAVMAV_4761
MITOCO_46700
MIAOCU_46430
MIDMIP_07069
MYOOEM_46820
MCHIAN480_24315
MIROCQ_47730
MMALCKJ54_22215(fgd)
MLPMLM_3925
MMANMMAN_34870(fgd)
MSERMTY59_09930(fgd)
MSAMycsm_00421
MULMUL_2814(fgd1)
MMIMMAR_0709(fgd1)
MMAEMMARE11_06580(fgd1)
MLIMULP_00708(fgd1)
MPSEMPSD_08240(fgd1)
MSHOMSHO_24430(fgd1)
MMCMmcs_0532
MKMMkms_0544
MJLMjls_0522
MMMW7S_23445
MKNMKAN_17810
MYVG155_03925 G155_27960
MYEAB431_03120
MHADB586_00345
MDXBTO20_32085
MSHGMSG_00606(fgd1)
MFJMFLOJ_28830(fgd1)
MSTOMSTO_32700(fgd1)
MSIMMSIM_18630(fgd)
MSAKMSAS_40240(fgd)
MKUI2456_03665(fgd)
MLWMJO58_03245(fgd)
MXEMYXE_44100(fgd1)
MNVMNVI_21840(fgd1)
MPAGC0J29_03905(fgd)
MNMMNVM_14410(fgd1)
MGORH0P51_03660(fgd)
MCOOMCOO_37840(fgd)
MBAIMB901379_00591(fgd1_2)
MSEOMSEO_45210(fgd1)
MHEKJMUB5695_04291(fgd1)
MGAUMGALJ_49550(fgd)
MLJMLAC_37680(fgd1)
MBRDMBRA_10730(fgd1)
MSHJMSHI_30490(fgd1)
MMAMK3U93_02970(fgd)
MSPGF6B93_02790(fgd)
MOTLTS72_22455(fgd)
MLMMLPF_0197(fgd1)
MPAAMKK62_22080(fgd)
MMEHM5I08_21315(fgd)
MKYIWGMT90018_07110(fgd1)
MADIA7U43_27100
MWUPT015_20480(fgd)
MYWBVC93_07190 BVC93_12385 BVC93_16870
MSMMSMEG_0777
MSGMSMEI_0761(fgd1)
MSBLJ00_03860
MSNLI99_03860
MSHLI98_03860
MVAMvan_0698
MGIMflv_0211
MSPMspyr1_05660
MCBMycch_0470
MNED174_04730
MYNMyAD_04630
MFTXA26_07380 XA26_56510
MPHLMPHLCCUG_04650(fgd_8)
MVQMYVA_0536
MLLB1R94_03355
MRHMycrhN_1287
MTHN4412656_00482(fgd1_1) 4412656_01048(fgd1_2)
MHASMHAS_04717(fgd1_8)
MDUMDUV_38570(fgd)
MCHTMCHIJ_04790(fgd_1) MCHIJ_36400(fgd_2)
MDRMDOR_02320(fgd)
MAUUNCTC10437_00531(fgd1_1)
MMAGMMAD_07420(fgd)
MMORMMOR_60040(fgd)
MFXMFAL_23270(fgd1)
MAICMAIC_50370(fgd)
MIJMINS_10030(fgd1)
MALVMALV_29790(fgd)
MTYMTOK_07490(fgd_1) MTOK_26600(fgd_2) MTOK_55610(fgd_3)
MPSCMPSYJ_03910(fgd)
MARZMARA_32600(fgd)
MGADMGAD_47980(fgd)
MHEVMHEL_16140(fgd)
MSARMSAR_21660(fgd)
MANYMANY_45990(fgd1)
MAUBMAUB_25430(fgd)
MPOFMPOR_10370(fgd)
MPHUMPHO_44950(fgd)
MMUCC1S78_024775(fgd)
MMATMMAGJ_36040(fgd)
MBOKMBOE_19230(fgd)
MFGK6L26_28005(fgd)
MSEIMSEDJ_18720(fgd)
MFLVNCTC10271_04617(fgd1_8)
MCEEMCEL_28340(fgd)
MBRML2Z93_003489(fgd)
MMONEWR22_02825(fgd)
MGOAFA91_01520
MHOLK3U96_23730(fgd)
MSENK3U95_03775(fgd)
MPAEK0O64_02830(fgd)
MRFMJO55_02565(fgd)
MDFK0O62_03665(fgd) K0O62_05590(fgd)
MCROMI149_03490(fgd)
MGROFZ046_09105(fgd)
MAUSJN090_02335(fgd)
MFREEXE63_11430(fgd)
MKRMKOR_26810(fgd)
MPAKMIU77_16810(fgd)
MABMAB_4230c
MMVMYCMA_2354
MABBMASS_4265
MABLMMASJCM_4316
MCHEBB28_21790
MIZBAB75_24220
MSTEMSTE_04406(fgd)
MSAOMYCSP_19820
MSALDSM43276_04110(fgd1_3)
MJDJDM601_0380(fgd1)
MTER4434518_00378(fgd1_2)
MMINMMIN_20990(fgd1)
MHIBMHIB_39070(fgd1)
MHERK3U94_02215(fgd)
MVMMJO54_01970(fgd)
ASDAS9A_0529
NFANFA_53550
NFRERS450000_04516(fgd1_4)
NCYNOCYR_5193(fgd)
NBRO3I_033215 O3I_040080
NNONONO_c72250(fgd)
NSLBOX37_13120 BOX37_30605
NSRNS506_01163(fgd1)
NTPCRH09_37790(fgd)
NOZDMB37_18815(fgd)
NODFOH10_33410(fgd)
NAHF5544_42530(fgd)
NADNCTC11293_00334(fgd1_1)
NWLNWFMUON74_67690(fgd)
NIEKV110_39155(fgd)
NTCKHQ06_04290(fgd) KHQ06_30620(fgd)
NHUH0264_37580(fgd)
NYALTV02_33370(fgd)
NGPLTT66_09940(fgd)
NSPUIFM12276_59910(fgd)
NYUD7D52_29090(fgd)
RHARHA1_ro02204 RHA1_ro11062 RHA1_ro11166
RERRER_14710(fdg)
REYO5Y_06970
REBXU06_07215
RQIC1M55_07460(fgd)
ROPROP_19180(fdg)
ROAPd630_LPD06384
RPYY013_10170 Y013_12045 Y013_14290
RHBNY08_4549
RAVAAT18_20205 AAT18_24575
RHWBFN03_13335
RRZCS378_09650(fgd)
RHUA3Q40_00093(fgd1_1)
RHQIM25_03715
RHODAOT96_17855
RRT4535765_03876(fgd1_4) 4535765_04398(fgd)
RCRNCTC10994_02977(fgd1_3) NCTC10994_03408(fgd1_4)
RTMG4H71_14525(fgd)
RKOJWS14_11505(fgd) JWS14_40335(fgd) JWS14_43455(fgd)
RGOKYT97_11235(fgd)
ROZCBI38_07135
RPSKJWS13_28335(fgd) JWS13_34375(fgd)
RGORNMQ04_18805(fgd)
RANTRHODO2019_10330(fgd)
RHOPD8W71_26095(fgd)
RHOORA302_07355(fgd)
RHOUKZJ41_21310(fgd) KZJ41_26035(fgd)
RHOWA4U64_04515 A4U64_26600
RHOJJVH1_02655(fgd) JVH1_26275(fgd) JVH1_40015(fgd)
RFAA3L23_02644(fgd_2)
RHSA3Q41_00717(fgd_1)
REQREQ_39220
PDEFP9209_08615(fgd)
WHROG579_15995(fgd)
GBRGbro_4404
GPOGPOL_c06320
GORKTR9_4263
GOQACH46_02275
GTABCM27_22820
GOCCXX93_05015(fgd)
GITC6V83_17875(fgd)
GRUGCWB2_21935(fgd9)
GOMD7316_04102(fgd1_5)
GAVC5O27_06470(fgd)
GODGKZ92_20910(fgd)
GOSQAD21_21660(fgd)
GOJGR168_20715(fgd)
GAMGII34_20565(fgd)
GPDGII33_02230(fgd)
GJIH1R19_20985(fgd)
GOILK459_11175(fgd)
GHNMVF96_21620(fgd)
GAMIIHQ52_01465(fgd)
GMGNWF22_07915(fgd)
GSIP5P27_17245(fgd)
SPINKV203_19355(fgd)
TPRTpau_3763
TSMASU32_21450
TPULTPB0596_41050(fgd)
TSDMTP03_42420(fgd)
SRTSrot_0132
DTMBJL86_2857
DITC3V38_03570(fgd)
DIZCT688_14145(fgd)
DPCA6048_14795
DLUA6035_14135
DKNNHB83_12715(fgd) NHB83_14365(fgd)
DCDVYL96_13810(fgd)
TOYFO059_15025(fgd)
LXLKDY119_01322(fgd1)
PSICJ4E96_05750
MTSMTES_1878
MIOAOA12_18820 AOA12_18825
MCWA8L33_02340
MIHBJP65_10335
MLVCVS47_03053(fgd1_4)
MWAE4K62_17125(fgd)
MPRTET475_03920(fgd)
MSEDE3O41_12535(fgd)
MSFIT882_14570(fgd)
MCAWF6J84_13720(fgd)
MLZF6J85_16145(fgd)
MBINLXM64_14330(fgd)
MTECOAU46_00555(fgd)
MELYL2X98_28685(fgd)
MSUWGCM10025863_29290
MRGSM116_03180(fgd)
MINVT9R20_15330(fgd)
MOJD7D94_11945(fgd)
MLIYRYJ27_01230(fgd)
MICEEHF32_14355(fgd)
MAUGKV397_17200(fgd)
MSUFKV394_04900(fgd)
MHOTPU630_13980(fgd)
RTXTI83_03470
RTCAPU90_03000
RTNA6122_2035
RRYC1O28_02860(fgd)
RIAC7V51_08335(fgd)
RFSC1I64_01805(fgd)
RTEGSU10_11025(fgd)
ROEQ0F99_01830(fgd)
MVDAWU67_15845 AWU67_15860
AGYATC03_18485 ATC03_18500
AGMDCE93_13670(fgd) DCE93_13680
AGFET445_04895 ET445_04905(fgd)
AARCG127AT_06820 G127AT_10270(fgd)
AMAUDSM26151_28140(fgd1_3) DSM26151_28170(fgd1_4)
ASOIMTP13_06240 MTP13_06250(fgd)
AMAVGCM10025877_13540(fgd) GCM10025877_13570
ALAVMTO99_13425(fgd) MTO99_13435
AILFLP10_09965 FLP10_09975(fgd)
CARTPA27867_3315
CRYB7495_16100
CPHYB5808_18565
CHREIE160_09635(fgd)
MHUMNNL39_01530(fgd)
MDBOVN18_08050(fgd)
MYLC3E77_12900 C3E77_13165(fgd)
SALCC2138_12535 C2138_12560(fgd)
SALAESZ53_05065 ESZ53_05085(fgd)
SALDFVA74_01065(fgd) FVA74_01095
HUMDVJ78_03025(fgd)
HUWFPZ11_07385
GRYD7I44_06945 D7I44_11930(fgd)
LYDD7I47_09920(fgd) D7I47_09955
LYKFLP23_11770 FLP23_11780(fgd)
PROAH4J02_03820(fgd) H4J02_03885
AGGC1N71_13755(fgd)
AGROJSQ78_08660(fgd)
MANTBHD05_14700 BHD05_14860
HEAHL652_00215(fgd) HL652_10875
HEHL3i23_06150(fgd)
GLNF1C58_01610(fgd) F1C58_11320
AGXAGREI_0996
SUBTKPL76_03615(fgd) KPL76_08045
SUBALQ955_10155 LQ955_15020(fgd)
HOMOF852_06455(fgd)
NAEIGCM126_22230(fgd)
AOGLH407_06235(fgd) LH407_06805(fgd)
ACRYAC20117_12450
AJGKKR91_03245
ASUNKG104_02960
ACAONF551_09375
AGEGMUG94_02855
AKON9A08_09060
AJRN2K98_15955(fgd)
BCVBcav_1687 Bcav_2587
JDEJden_0208
LMOIVV02_19860
YIMJ5M86_00770(fgd)
ALXLVQ62_16510(fgd)
BEIGCM100_10260(fgd)
XCEXcel_1130
XYLET495_01885
XYAET471_11110
IVAIsova_1101
IDOI598_1122(fgd1_1)
CETB8281_15250
CCEUCBR64_16115
CPRTFIC82_014140
SKESked_24120
SANWG7063_05810
CFLCfla_1412
CFICelf_1441
CGACelgi_2158
CEZCBP52_02580
CELZE5225_11105
CEJGC089_11435
CELHGXP71_04020
CIRALFM56_11125
CPALF1D97_09385
CELCK5O09_06650
CDONKKR89_06910
CWANKG103_07155
CFENKG102_06190 KG102_18290(fgd)
CWNNP075_07190
CCHENP064_10595
CXIENP048_07020
CELEP9841_03675
OEKFFI11_010900
PSEIGCE65_07065(fgd) GCE65_10885
PSEKGCM125_00180 GCM125_32870
ICAIntca_2335
ARSADJ73_01095
TEHGKE56_03050(fgd)
PHWG7075_14630(fgd)
PEIH9L10_15335(fgd)
TEDU5C87_19330(fgd)
SERJSGUI_0136
SERWFY030_09045
ORNDV701_08880(fgd)
ORZFNH13_02605(fgd) FNH13_06355(fgd)
OCPNF557_10250(fgd)
OFANF556_01650(fgd)
AUSIPK37_05145(fgd)
GEZFE251_04605 FE251_14000(fgd)
GYUFE374_05885
HALTIM660_07120(fgd) IM660_07150 IM660_19315(fgd)
RHALLQF10_12460 LQF10_12505(fgd)
RSUALQF12_05775(fgd) LQF12_05805
DCPRN607_11995(fgd) RN607_12785
NOYEXE57_02500(fgd)
NOIFCL41_02525
NDPE2C04_02930
NPIG7071_12450(fgd)
NOQLN652_12900(fgd)
NFCKG111_09475
AEFGEV26_03320
ASEZH9L21_03180(fgd)
ADBNP095_03060(fgd)
AWNNQV15_14410
KFLKfla_0290
KQIF1D05_22080(fgd)
KSLOG809_13225(fgd)
KRIOX958_35150(fgd)
NMLNamu_0967
NAKEH165_03520(fgd)
NAKAH7F38_23230(fgd)
KRAKrad_3294
SVISvir_24550
SACCEYD13_13685(fgd3)
AMDAMED_3381
AMNRAM_17200
AMMAMES_3342
AMZB737_3342
AOIAORI_2463 AORI_3107(zwf)
AJAAJAP_23830(fgd) AJAP_26510
AMQAMETH_1817 AMETH_2250
AMYCCU254_17095(fgd) CU254_21825(fgd)
AMYBBKN51_04915 BKN51_07690
AABA4R43_16140
AMYYYIM_14365(fgd5) YIM_33190(fgd13)
AORISD37_13370 SD37_15860
AACDLWP59_25725(fgd) LWP59_29300
APRTMUY14_18585(fgd)
AROONQK81_07060(fgd) NQK81_10035
ATHML1857_14010(fgd) L1857_25730(fgd)
ARHDVSH64_01645 VSH64_06270(fgd)
AMOGQRX60_34250(fgd)
ACYNORV05_10390(fgd)
ACORLCL61_01140 LCL61_30290(fgd)
AMYZHUW46_00875(fgd1_2)
PDXPsed_3151
PSEEFRP1_10925
PSEHXF36_10660
PSEQAD006_20030
PECQAD017_27870
PHHAFB00_26475
PAUTPdca_34970(fgd_1) Pdca_36050(fgd_2)
PBROHOP40_25420(fgd)
PPELH6H00_24100(fgd)
PSDSK1T35_24605(fgd)
SESPBN6_24600(fgd1)
AHMTL08_09500
ACTIUA75_09630
ACADUA74_09660
AHGAHOG_09035(fgd2)
ACTAC1701_20095(fgd)
PMADBAY61_12105
MCABHXZ27_15920(fgd)
ASEACPL_6651(fdg)
AMSAMIS_64150
ACTNL083_6206(fdg)
ACTSACWT_6521
AIHAiant_24380(fgd)
ACTRAsp14428_70060(fgd)
ACTLL3i22_089350(fgd)
ASICQ0Z83_105810(fgd)
AOUACTOB_006936(fgd)
ACTEACTI_04330(fgd)
AFSAFR_31800
PFLAPflav_072210
PSUUPsuf_034970(fgd)
CCAZCOUCH_12355(fgd)
CAICaci_5308
EKEEK0264_02690(fgd)
JTLM6D93_14930(fgd)
JCYM6B22_08545(fgd)
RXYRxyl_0217
RRDRradSPS_2686
RUBGBA63_00485
BSOLFSW04_06975(fgd)
BALADSM104299_00852(fgd1_1)
CWOCwoe_4102 Cwoe_4111 Cwoe_4148
SBAEDSM104329_01957(fgd1_2) DSM104329_02946(fgd1_3)
RRSRoseRS_1140
RCARcas_3981
CAUCaur_2833
CHLChy400_3069
CAGCagg_1132
KBSEPA93_21855(fgd) EPA93_24215
KBBccbrp13_08230(fgd)
TTRTter_1861
TROtrd_A0676
STISthe_0032
MICAP0L94_12415(fgd)
MBAMbar_A0420
MBWMSBRW_0581
MBAKMSBR3_0043 MSBR3_2437
MMAMM_2195
MMAZMmTuc01_2246
MMJMSMAS_2491
MMACMSMAC_1949
MTHRMSTHT_0039
MTHEMSTHC_0689
MHORMSHOH_1356 MSHOH_3134
MFZAOB57_002345
MZIHWN40_04715
MPDMCP_1470(fgd)
RCIRCIX1283(fgd-1) RRC242(fgd-2)
SALRFQU85_03380
HALREFA46_010650
SALIL593_11930
HALJG9465_19970 G9465_20010
NHOHWV23_16060
HMUHmuk_0326
HALZE5139_04915
HALLLC1Hm_2856(fdg1)
HAZPGBQ70_04910
HTUHtur_4387
HSALJMJ58_23055
HXAHalxa_2240
HLRHALLA_00755
NGANgar_c06360
NVNNVIE_013150
NEVNTE_02717
TAANMY3_01705(fgd1_3)
NFNNFRAN_1153
CSUCSUB_C0344 CSUB_C0669
 » show all
Reference
1  [PMID:8631674]
  Authors
Purwantini E, Daniels L
  Title
Purification of a novel coenzyme F420-dependent glucose-6-phosphate dehydrogenase from Mycobacterium smegmatis.
  Journal
J Bacteriol 178:2861-6 (1996)
DOI:10.1128/JB.178.10.2861-2866.1996
  Sequence
Reference
2  [PMID:17376702]
  Authors
Bashiri G, Squire CJ, Baker EN, Moreland NJ
  Title
Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system.
  Journal
Protein Expr Purif 54:38-44 (2007)
DOI:10.1016/j.pep.2007.01.014
  Sequence
[mtu:Rv0407]
Reference
3  [PMID:8997717]
  Authors
Purwantini E, Gillis TP, Daniels L
  Title
Presence of F420-dependent glucose-6-phosphate dehydrogenase in Mycobacterium and Nocardia species, but absence from Streptomyces and Corynebacterium species and methanogenic Archaea.
  Journal
FEMS Microbiol Lett 146:129-34 (1997)
DOI:10.1111/j.1574-6968.1997.tb10182.x
Other DBs
ExplorEnz - The Enzyme Database: 1.1.98.2
IUBMB Enzyme Nomenclature: 1.1.98.2
ExPASy - ENZYME nomenclature database: 1.1.98.2
BRENDA, the Enzyme Database: 1.1.98.2
LinkDB

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