Entry
Name
glucose-6-phosphate dehydrogenase (coenzyme-F420);
coenzyme F420-dependent glucose-6-phosphate dehydrogenase;
F420-dependent glucose-6-phosphate dehydrogenase;
FGD1;
Rv0407;
F420-dependent glucose-6-phosphate dehydrogenase 1
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With other, known, physiological acceptors
BRITE hierarchy
Sysname
D-glucose-6-phosphate:F420 1-oxidoreductase
Reaction(IUBMB)
D-glucose 6-phosphate + oxidized coenzyme F420 = 6-phospho-D-glucono-1,5-lactone + reduced coenzyme F420 [RN:
R09550 ]
Reaction(KEGG)
Substrate
D-glucose 6-phosphate [CPD:
C00092 ];
oxidized coenzyme F420 [CPD:
C00876 ]
Product
6-phospho-D-glucono-1,5-lactone [CPD:
C01236 ];
reduced coenzyme F420 [CPD:
C01080 ]
Comment
The enzyme is very specific for D-glucose 6-phosphate. No activity with NAD+, NADP+, FAD and FMN [1].
History
EC 1.1.98.2 created 2010 as EC 1.1.99.34, transferred 2011 to EC 1.1.98.2
Orthology
K15510 coenzyme F420-dependent glucose-6-phosphate dehydrogenase
Genes
MMAE : MMARE11_06580(fgd1)
MYV : G155_03925 G155_27960
MBAI : MB901379_00591(fgd1_2)
MHEK : JMUB5695_04291(fgd1)
MKY : IWGMT90018_07110(fgd1)
MYW : BVC93_07190 BVC93_12385 BVC93_16870
MFT : XA26_07380 XA26_56510
MPHL : MPHLCCUG_04650(fgd_8)
MTHN : 4412656_00482(fgd1_1) 4412656_01048(fgd1_2)
MCHT : MCHIJ_04790(fgd_1) MCHIJ_36400(fgd_2)
MAUU : NCTC10437_00531(fgd1_1)
MTY : MTOK_07490(fgd_1) MTOK_26600(fgd_2) MTOK_55610(fgd_3)
MFLV : NCTC10271_04617(fgd1_8)
MDF : K0O62_03665(fgd) K0O62_05590(fgd)
MSAL : DSM43276_04110(fgd1_3)
MTER : 4434518_00378(fgd1_2)
NFR : ERS450000_04516(fgd1_4)
NBR : O3I_033215 O3I_040080
NSL : BOX37_13120 BOX37_30605
NAD : NCTC11293_00334(fgd1_1)
NWL : NWFMUON74_67690(fgd)
NTC : KHQ06_04290(fgd) KHQ06_30620(fgd)
NSPU : IFM12276_59910(fgd)
RHA : RHA1_ro02204 RHA1_ro11062 RHA1_ro11166
RPY : Y013_10170 Y013_12045 Y013_14290
RAV : AAT18_20205 AAT18_24575
RRT : 4535765_03876(fgd1_4) 4535765_04398(fgd)
RCR : NCTC10994_02977(fgd1_3) NCTC10994_03408(fgd1_4)
RKO : JWS14_11505(fgd) JWS14_40335(fgd) JWS14_43455(fgd)
RPSK : JWS13_28335(fgd) JWS13_34375(fgd)
RANT : RHODO2019_10330(fgd)
RHOU : KZJ41_21310(fgd) KZJ41_26035(fgd)
RHOW : A4U64_04515 A4U64_26600
RHOJ : JVH1_02655(fgd) JVH1_26275(fgd) JVH1_40015(fgd)
DKN : NHB83_12715(fgd) NHB83_14365(fgd)
MIO : AOA12_18820 AOA12_18825
MVD : AWU67_15845 AWU67_15860
AGY : ATC03_18485 ATC03_18500
AGM : DCE93_13670(fgd) DCE93_13680
AGF : ET445_04895 ET445_04905(fgd)
AARC : G127AT_06820 G127AT_10270(fgd)
AMAU : DSM26151_28140(fgd1_3) DSM26151_28170(fgd1_4)
ASOI : MTP13_06240 MTP13_06250(fgd)
AMAV : GCM10025877_13540(fgd) GCM10025877_13570
ALAV : MTO99_13425(fgd) MTO99_13435
AIL : FLP10_09965 FLP10_09975(fgd)
MYL : C3E77_12900 C3E77_13165(fgd)
SALC : C2138_12535 C2138_12560(fgd)
SALA : ESZ53_05065 ESZ53_05085(fgd)
SALD : FVA74_01065(fgd) FVA74_01095
GRY : D7I44_06945 D7I44_11930(fgd)
LYD : D7I47_09920(fgd) D7I47_09955
LYK : FLP23_11770 FLP23_11780(fgd)
PROA : H4J02_03820(fgd) H4J02_03885
MANT : BHD05_14700 BHD05_14860
HEA : HL652_00215(fgd) HL652_10875
GLN : F1C58_01610(fgd) F1C58_11320
SUBT : KPL76_03615(fgd) KPL76_08045
SUBA : LQ955_10155 LQ955_15020(fgd)
AOG : LH407_06235(fgd) LH407_06805(fgd)
CFEN : KG102_06190 KG102_18290(fgd)
PSEI : GCE65_07065(fgd) GCE65_10885
PSEK : GCM125_00180 GCM125_32870
ORZ : FNH13_02605(fgd) FNH13_06355(fgd)
GEZ : FE251_04605 FE251_14000(fgd)
HALT : IM660_07120(fgd) IM660_07150 IM660_19315(fgd)
RHAL : LQF10_12460 LQF10_12505(fgd)
RSUA : LQF12_05775(fgd) LQF12_05805
DCP : RN607_11995(fgd) RN607_12785
AOI : AORI_2463 AORI_3107(zwf)
AJA : AJAP_23830(fgd) AJAP_26510
AMQ : AMETH_1817 AMETH_2250
AMYC : CU254_17095(fgd) CU254_21825(fgd)
AMYB : BKN51_04915 BKN51_07690
AMYY : YIM_14365(fgd5) YIM_33190(fgd13)
AORI : SD37_13370 SD37_15860
AACD : LWP59_25725(fgd) LWP59_29300
AROO : NQK81_07060(fgd) NQK81_10035
ATHM : L1857_14010(fgd) L1857_25730(fgd)
ARHD : VSH64_01645 VSH64_06270(fgd)
ACOR : LCL61_01140 LCL61_30290(fgd)
AMYZ : HUW46_00875(fgd1_2)
PAUT : Pdca_34970(fgd_1) Pdca_36050(fgd_2)
ACTR : Asp14428_70060(fgd)
BALA : DSM104299_00852(fgd1_1)
CWO : Cwoe_4102 Cwoe_4111 Cwoe_4148
SBAE : DSM104329_01957(fgd1_2) DSM104329_02946(fgd1_3)
KBS : EPA93_21855(fgd) EPA93_24215
MBAK : MSBR3_0043 MSBR3_2437
MHOR : MSHOH_1356 MSHOH_3134
RCI : RCIX1283(fgd-1) RRC242(fgd-2)
HALJ : G9465_19970 G9465_20010
CSU : CSUB_C0344 CSUB_C0669
» show all
Taxonomy
Reference
Authors
Purwantini E, Daniels L
Title
Purification of a novel coenzyme F420-dependent glucose-6-phosphate dehydrogenase from Mycobacterium smegmatis.
Journal
Sequence
Reference
Authors
Bashiri G, Squire CJ, Baker EN, Moreland NJ
Title
Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system.
Journal
Sequence
Reference
Authors
Purwantini E, Gillis TP, Daniels L
Title
Presence of F420-dependent glucose-6-phosphate dehydrogenase in Mycobacterium and Nocardia species, but absence from Streptomyces and Corynebacterium species and methanogenic Archaea.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 1.1.98.2
ExPASy - ENZYME nomenclature database: 1.1.98.2
LinkDB
All DBs