KEGG ENZYME: 1.13.11.70

ENZYME: 1.13.11.70

Entry

EC 1.13.11.70               Enzyme

Name

all-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase;
CCD8 (gene name);
MAX4 (gene name);
NCED8 (gene name);
all-trans-10'-apo-beta-carotenal:O2 oxidoreductase (13,14-cleaving)

Class

Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen

Sysname

all-trans-10'-apo-beta-carotenal:oxygen oxidoreductase (13,14-cleaving)

Reaction(IUBMB)

all-trans-10'-apo-beta-carotenal + O2 = 13-apo-beta-carotenone + (2E,4E,6E)-4-methylocta-2,4,6-trienedial [RN:R10560]

Reaction(KEGG)

R10560

Substrate

all-trans-10'-apo-beta-carotenal [CPD:C20695];
O2 [CPD:C00007]

Product

13-apo-beta-carotenone [CPD:C20696];
(2E,4E,6E)-4-methylocta-2,4,6-trienedial [CPD:C20697]

Comment

Requires Fe2+. The enzyme from the plant Arabidopsis thaliana also catalyses EC 1.13.11.69, carlactone synthase, 10-fold faster.

History

EC 1.13.11.70 created 2012

Orthology

K17913

carlactone synthase / all-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase

Genes

GAE:

121381261

HCRA:

139464547

RPHI:

132733202 132740861

DPOL:

127855520

ATH:	AT4G32810(CCD8)

ALY:

9303300

CRB:

17880263

CSAT:

104716888 104721542 104729987

EUS:	EUTSA_v10024788mg

BRP:

103850421

BNA:	106371158 106372794 106375326

BOE:	106297618 106329062

RSZ:

108842462

THJ:

104820078

CPAP:

110825785

CIT:	102611969 102612266

CIC:	CICLE_v100080502m CICLE_v10010609mg

PVY:

116140704

MINC:

123199959

TCC:

18587976

GRA:	105762895 105772277

GHI:	107897099 107900521 107901528 107953845

GAB:	108456530 108484843

HSYR:

120114869 120192424

DZI:

111285387

EGR:	104437781 104439926

RARG:

115750116 115750117

GMX:	100794831(CCD8) 100814148

GSJ:	114409123 114415154

PVU:

137822764

VRA:

106761448

VAR:

108321824

VUN:

114164054

VUM:

124846922

CCAJ:

109799996

APRC:

113865831

MTR:	11423389 25498599

TPRA:

123893697

CAM:

101497957

PSAT:

127084460

VVO:	131654774 131660047 131660078

LJA:

130727599

ADU:

107470782

AIP:

107623923

AHF:	112716107 112784190

LANG:

109339284

PCIN:

129294682

QSA:	O6P43_015496 O6P43_019476

FVE:

101301466

AANS:

126783307

RCN:

112174794

PPER:

18789175

PMUM:

103320239

PAVI:

110761281

PDUL:

117615262

MDM:	103415461 103441305

MSYL:

126605834 126631671

PXB:

103957092

PCOX:

137712575 137716826

ZJU:

107420451

MNT:

21393994

CSAV:

115705408

CSV:

101216826

CMO:	103488182(CCD8)

BHJ:

120075818

CMAX:

111492518 111496443

CMOS:

111462801

CPEP:

111799272 111805686

RCU:

8275656

MEAN:

126659901

JCU:

105638200

HBR:

110648761

MESC:

110603430

POP:	7462922 7470743

PEU:	105115287 105122413

PALZ:

118030684 118053670

PNZ:	133673778 133690351

JRE:	108979513 109009492

CILL:

122317316 122319391

CAVE:

132190259

AGLU:

133870186

QLO:

115970744

TWL:	119996237 120006063

VVI:

100250765

VRI:

117913640

SLY:

101254620

SPEN:

107028115

SOT:

102595155

SSTN:

125867805

SDUL:

129888360

CANN:

107839011

LBB:

132638345

NTA:	107812793(MAX4) 107821949

NSY:

104228402

NTO:

104117083

NAU:

109209147

INI:

109179896

ITR:

116007402

SIND:

105156117 105165056

OEU:	111368646 111382711

EGT:

105977052

SSPL:

121778526 121780680 121781645 121781646 121781647

SMIL:

131015360

SHIS:

125189856 125210458 125211935

APAN:

127265742

HAN:	110923712 110926648

ECAD:

122583226 122583924 122586050

LSV:	111877582 111891276

CCAV:

112520444 112521686

DCR:

108215310

CSIN:

114275767

RVL:

131316510

AEW:	130757015 130765802

DLT:

127813530

BVG:

104885388

SOE:	110787413 130466182

CQI:	110683157 110705573 110728350

ATRI:

130802878

MOF:

131151810

NNU:

104592092

MING:

122072068 122089718

TSS:

122654905

PSOM:

113353973

OSA:	4326177(CCD8B) 4327933(CCD8A)

DOSA:

Os01g0566500 Os01g0746400

OBR:

102709984

OGL:	127757444 127770488

BDI:

100831734

ATS:	109738648 109753493 109753519 109758391

TDC:	119271872 119271874 119271875 119279309 119281469 119357533

TAES:

123056732 123058519 123065607 123067325 123074700 123133128 123191449

TUA:	125530689 125540847 125548561

LPER:

127316308 127343829

LRD:	124656146 124663088 124704073

SBI:	8057987 8062181 8064382

ZMA:

100502522

MFLO:

136452961 136453219 136460995 136480067 136547262

SITA:

101763948 101767361 101767759 101774274

SVS:	117855476 117855776 117858388 117866430

PVIR:

120672308 120674971 120684890 120708023 120708024

PHAI:

112894589 112894614 112903092

PAUA:

133889621 133910082

PDA:	103717867 103722026

EGU:	105041959 105047448

MUS:	135605623 135613951

ZOF:	121999968 122003597 122016439 122048030

DCT:

110092372

PEQ:

110030749

AOF:

109842452

MSIN:

131222979

ACAK:

137937360 137940926

NCOL:

116244921

ATR:	18441191 18443367

CJF:	131030466 131045646 131045647 131045689 131052151 131052180 131079851 131079860 131864801

SMO:	SELMODRAFT_127411(MAX4-2) SELMODRAFT_173016(MAX4-1)

PPP:

112283943

CRE:	CHLRE_02g073900v5 CHLRE_02g073950v5 CHLRE_08g365851v5

VCN:	VOLCADRAFT_107173 VOLCADRAFT_108590 VOLCADRAFT_108622 VOLCADRAFT_108677

MNG:

MNEG_9548

CSL:	COCSUDRAFT_67504

AAF:	AURANDRAFT_69593

» show all

Reference

1 [PMID:15342640]

Authors

Schwartz SH, Qin X, Loewen MC

Title

The biochemical characterization of two carotenoid cleavage enzymes from Arabidopsis indicates that a carotenoid-derived compound inhibits lateral branching.

Journal

J Biol Chem 279:46940-5 (2004)
DOI:10.1074/jbc.M409004200

Sequence

[ath:AT4G32810]

Other DBs

ExplorEnz - The Enzyme Database:

1.13.11.70

IUBMB Enzyme Nomenclature:

1.13.11.70

ExPASy - ENZYME nomenclature database:

1.13.11.70

BRENDA, the Enzyme Database:

1.13.11.70

LinkDB

DBGET integrated database retrieval system