KEGG ENZYME: 1.14.14.134

ENZYME: 1.14.14.134

Entry

EC 1.14.14.134              Enzyme

Name

beta-amyrin 24-hydroxylase;
sophoradiol 24-hydroxylase;
CYP93E1

Class

Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

Sysname

beta-amyrin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (24-hydroxylating)

Reaction(IUBMB)

(1) beta-amyrin + [reduced NADPH---hemoprotein reductase] + O2 = 24-hydroxy-beta-amyrin + [oxidized NADPH---hemoprotein reductase] + H2O [RN:R09604];
(2) sophoradiol + [reduced NADPH---hemoprotein reductase] + O2 = 24-hydroxysophoradiol + [oxidized NADPH---hemoprotein reductase] + H2O [RN:R09605]

Reaction(KEGG)

R09604 R09605

Substrate

beta-amyrin [CPD:C08616];
[reduced NADPH---hemoprotein reductase] [CPD:C03024];
O2 [CPD:C00007];
sophoradiol [CPD:C19733]

Product

24-hydroxy-beta-amyrin [CPD:C19732];
[oxidized NADPH---hemoprotein reductase] [CPD:C03161];
H2O [CPD:C00001];
24-hydroxysophoradiol [CPD:C08980]

Comment

A cytochrome P-450 (heme-thiolate) protein. Found in plants and participates in the biosynthesis of soybean saponins.

History

EC 1.14.14.134 created 2011 as EC 1.14.99.43, transferred 2018 to EC 1.14.14.134

Pathway

ec00909