KEGG ENZYME: 1.14.15.46

ENZYME: 1.14.15.46

Entry

EC 1.14.15.46               Enzyme

Name

2-methoxy-6-polyprenylphenol 4-hydroxylase;
COQ6 (ambiguous)

Class

Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor

Sysname

2-methoxy-6-(all-trans-polyprenyl)phenol,ferredoxin:oxygen oxidoreductase (4-hydroxylating)

Reaction(IUBMB)

2-methoxy-6-(all-trans-polyprenyl)phenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+ = 2-methoxy-6-(all-trans-polyprenyl)-1,4-benzoquinol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O [RN:R13426]

Reaction(KEGG)

R13426

Substrate

2-methoxy-6-(all-trans-polyprenyl)phenol [CPD:C17552];
reduced [2Fe-2S]-[ferredoxin];
O2 [CPD:C00007];
H+ [CPD:C00080]

Product

2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol [CPD:C19858];
oxidized [2Fe-2S]-[ferredoxin];
H2O [CPD:C00001]

Comment

The enzyme, found in eukaryotes, is involved in the biosynthesis of ubiquinone. The vertebrate enzyme catalyses two hydroxylations in the pathway at the positions meta to the prenyl side chain (the other hydroxylation is classified as EC 1.14.15.45, 4-hydroxy-3-polyprenylbenzoate 5-hydroxylase). The number of isoprenoid subunits in the side chain varies in different species. The enzyme does not have any specificity concerning the length of the polyprenyl tail, and accepts tails of various lengths with similar efficiency.

History

EC 1.14.15.46 created 2024

Pathway

ec00130

Ubiquinone and other terpenoid-quinone biosynthesis

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K06126

4-hydroxy-3-polyprenylbenzoate 5-hydroxylase / 2-methoxy-6-polyprenylphenol 4-hydroxylase

Genes

HSA:	51004(COQ6)

PTR:	740390(COQ6)

PPS:	100976161(COQ6)

GGO:	101142359(COQ6)

PON:	100452642(COQ6)

PPYG:

129012268(COQ6)

NLE:	100604417(COQ6)

HMH:	116485050(COQ6)

SSYN:

129487672(COQ6)

MCC:	698047(COQ6)

MCF:	102120286(COQ6)

MTHB:

126959531

MNI:	105495805(COQ6)

CSAB:

103229321(COQ6)

CATY:

105590840(COQ6)

PANU:

101007681(COQ6)

TGE:	112628795(COQ6)

MLEU:

105540780(COQ6)

RRO:	104677559(COQ6)

RBB:	108534901(COQ6)

TFN:	117069352(COQ6)

PTEH:

111520724(COQ6)

CANG:

105517319(COQ6)

CJC:	100389329(COQ6)

SBQ:	101035430(COQ6)

CIMI:

108304474(COQ6)

ANAN:

105707220(COQ6)

CSYR:

103253961(COQ6)

MMUR:

105858506(COQ6)

LCAT:

123646868(COQ6)

PCOQ:

105819874(COQ6)

OGA:	100947326(COQ6)

MMU:	217707(Coq6)

MCAL:

110306787(Coq6)

MPAH:

110324874(Coq6)

RNO:	299195(Coq6)

MCOC:

116079567(Coq6)

ANU:	117697118(Coq6)

ASYL:

127687127(Coq6)

MUN:	110546973(Coq6)

CGE:	100751162(Coq6)

MAUA:

101837388(Coq6)

PROB:

127230967(Coq6)

PLEU:

114698255(Coq6)

MORG:

121452122(Coq6)

MFOT:

126515132

AAMP:

119820017(Coq6)

NGI:	103747369(Coq6)

HGL:	101706068(Coq6)

CPOC:

100731940(Coq6)

CCAN:

109688403(Coq6)

DORD:

105986586(Coq6)

DSP:	122118656(Coq6)

PLOP:

125363617(Coq6)

NCAR:

124976688

MMMA:

107149096(Coq6)

ITI:	101976423(Coq6)

OCU:

100342074

OPI:	101530363(COQ6)

TUP:	102471873(COQ6)

GVR:	103586288(COQ6)

CFA:	490778(COQ6)

CLUD:

112657223(COQ6)

VVP:	112927262(COQ6)

VLG:	121493861(COQ6)

NPO:	129495904(COQ6)

AML:	100479717(COQ6)

UMR:	103671276(COQ6)

UAH:	113270341(COQ6)

UAR:	123798991(COQ6)

ELK:

111148677

LLV:

125104996

MPUF:

101675245(COQ6)

MNP:	132000180(COQ6)

MLK:	131836888(COQ6)

NVS:	122893144(COQ6)

ORO:	101375270(COQ6)

EJU:	114200252(COQ6)

ZCA:	113909024(COQ6)

MLX:	118002635(COQ6)

NSU:	110571434(COQ6)

LWW:	102733938(COQ6)

FCA:	101090023(COQ6)

PYU:	121032029(COQ6)

PCOO:

112856010(COQ6)

PBG:	122469310(COQ6)

PVIV:

125169109(COQ6)

LRUF:

124512045

LGF:	123582006(COQ6)

AJU:

106974436

PTG:	102962491(COQ6)

PPAD:

109253813(COQ6)

PUC:

125908691

PLEZ:

122222924(COQ6)

HHV:	120231967(COQ6)

BTA:	511624(COQ6)

BOM:	102278708(COQ6)

BIU:	109565340(COQ6)

BBUB:

102415062(COQ6)

BBIS:

105000086(COQ6)

CHX:	102187685(COQ6)

OAS:	101105664(COQ6)

BTAX:

128053826(COQ6)

CSUM:

138073738(COQ6)

ODA:	120852732(COQ6)

CCAD:

122443847(COQ6)

MREE:

136172274(COQ6)

OVR:	110146182(COQ6)

MBEZ:

129562540(COQ6)

SSC:	100155731(COQ6)

CFR:	102524533(COQ6)

CBAI:

105074991(COQ6)

CDK:	105086116(COQ6)

VPC:	102526631(COQ6)

BACU:

103007291(COQ6)

BMUS:

118890300(COQ6)

LVE:	103075742(COQ6)

OOR:	101279084(COQ6)

LALB:

132514476(COQ6)

DLE:	111176267(COQ6)

PCAD:

102992518(COQ6)

PSIU:

116748372(COQ6)

NASI:

112394929(COQ6)

ECB:	100056420(COQ6)

EPZ:	103560625(COQ6)

EAI:	106827677(COQ6)

MYB:	102263591(COQ6)

MYD:	102756942(COQ6)

MMYO:

118657940(COQ6)

MLF:	102419226(COQ6)

MDT:	132231522(COQ6)

MYUM:

139011313(COQ6)

PKL:	118715391(COQ6)

EFUS:

103283589(COQ6)

MNA:	107533483(COQ6)

DRO:	112311856(COQ6)

SHON:

118976821(COQ6)

AJM:	119036255(COQ6)

PDIC:

114492251(COQ6)

PHAS:

123807965(COQ6)

MMF:	118629023(COQ6)

PPAM:

129065901(COQ6)

HAI:	109381564(COQ6)

RFQ:	117023798(COQ6)

PALE:

102885714(COQ6)

PGIG:

120619489(COQ6)

PVP:	105299240(COQ6)

RAY:

107505027

MJV:	108409336(COQ6)

TOD:	119239278(COQ6)

SARA:

101545764(COQ6)

SFUM:

130041500(COQ6)

SETR:

126004026(COQ6)

LAV:	100671170(COQ6)

TMU:

101350870

ETF:	101663777(COQ6)

DNM:	101411277(COQ6)

MDO:	100024139(COQ6)

GAS:	123235846(COQ6)

SHR:	100934559(COQ6)

AFZ:

127549515

PCW:	110208341(COQ6)

TVP:	118827956(COQ6)

PBRV:

138164398(COQ6)

OAA:	114815096(COQ6)

TACU:

119944635(COQ6)

GGA:	423342(COQ6)

PCOC:

116229387(COQ6)

MGP:	100540847(COQ6)

CJO:	107315086(COQ6)

TPAI:

128086269(COQ6)

LMUT:

125694301(COQ6)

NMEL:

110400921(COQ6)

APLA:

101794494(COQ6)

ACYG:

106038783(COQ6)

CATA:

118244850(COQ6)

AFUL:

116489666(COQ6)

TGU:	100222873(COQ6)

LSR:	110477214(COQ6)

SCAN:

103826532(COQ6)

PMOA:

120500392(COQ6)

OTC:	121331856(COQ6)

PRUF:

121356042(COQ6)

ATRC:

139589937(COQ6)

GFR:	102040421(COQ6)

FAB:	101819562(COQ6)

OMA:	130254128(COQ6)

PHI:	102106733(COQ6)

PMAJ:

107205896(COQ6)

CCAE:

111945532(COQ6)

CCW:	104685036(COQ6)

CBRC:

103621021(COQ6)

ACOE:

138111679(COQ6)

ETL:	114055981(COQ6)

ZAB:	102071448(COQ6)

ZLE:	135448025(COQ6)

ACHL:

103805616(COQ6)

SVG:	106861881(COQ6)

MMEA:

130575939(COQ6)

HRT:	120754426(COQ6)

SATI:

136363031(COQ6)

CCIC:

134045351(COQ6)

FPG:	101918589(COQ6)

FCH:	102047248(COQ6)

CCRI:

104159498(COQ6)

NNT:	104399926(COQ6)

SHAB:

115606052

ACUN:

113480568(COQ6)

TALA:

104367743(COQ6)

ACHC:

115352752(COQ6)

HALD:

104311214(COQ6)

HLE:	104841795(COQ6)

AGEN:

126049166

HHAR:

128139787(COQ6)

GCL:

127017374

CSTI:

104550854

LDI:	104344079(COQ6)

MNB:	103780389(COQ6)

DPUB:

104308202(COQ6)

PPUS:

135178483(COQ6)

AVIT:

104271844(COQ6)

BRHI:

104488147

EGZ:	104133242(COQ6)

NNI:	104021020(COQ6)

PCRI:

104024873(COQ6)

PCAO:

104045668(COQ6)

PADL:

103913030(COQ6)

AFOR:

103900105(COQ6)

FGA:	104081909(COQ6)

GSTE:

104257900(COQ6)

CLV:	102096125(COQ6)

MUI:	104544097(COQ6)

PGUU:

104459330(COQ6)

PLET:

104617920(COQ6)

EHS:	104514505(COQ6)

CMAC:

104473841(COQ6)

CUCA:

104061658(COQ6)

TEO:	104374261(COQ6)

BREG:

104630060(COQ6)

OHA:	104333967(COQ6)

ACAR:

104518421(COQ6)

CPEA:

104385423(COQ6)

CVF:	104288248(COQ6)

RTD:	128908617(COQ6)

CRID:

134515576(COQ6)

AAM:	106483043(COQ6)

AROW:

112977898(COQ6)

NPD:	112958049(COQ6)

TGT:	104579806(COQ6)

DNE:	112995427(COQ6)

SCAM:

104141586(COQ6)

AMJ:	102565837(COQ6)

CPOO:

109321206(COQ6)

GGN:	109298638(COQ6)

PSS:	102461389(COQ6)

CMY:	102944454(COQ6)

CCAY:

125639239(COQ6)

DCC:	119857459(COQ6)

CPIC:

101952074(COQ6)

TST:	117876408(COQ6)

CABI:

116837503(COQ6)

MRV:	120403091(COQ6)

ACS:	100555835(coq6)

ASAO:

132764676(COQ6)

PVT:	110086366(COQ6)

SUND:

121926931

PBI:	103055841(COQ6)

PMUR:

107290489(COQ6)

CTIG:

120311791(COQ6)

TSR:	106539294(COQ6)

PGUT:

117665810(COQ6)

APRI:

131187744(COQ6)

PTEX:

113443366(COQ6)

NSS:	113410052(COQ6)

VKO:	123026857(COQ6)

PMUA:

114592109(COQ6)

PRAF:

128409285(COQ6)

ZVI:	118082001(COQ6)

HCG:	128330706(COQ6)

GJA:	107123167(COQ6)

STOW:

125426517(COQ6)

EMC:	129324999(COQ6)

XLA:	108699845(coq6.S) 734620(coq6.L)

XTR:	448564(coq6)

NPR:	108802468(COQ6)

RTEM:

120921086(COQ6)

BBUF:

120982292(COQ6)

BGAR:

122921228(COQ6)

PWL:	138260226(COQ6)

MUO:	115477552(COQ6)

GSH:	117363747(COQ6)

DRE:	751691(coq6)

SRX:	107732250 107739237

SANH:

107662636 107664479(coq6)

SGH:	107559892 107586847

CCAR:

109089247 109089252(coq6)

CAUA:

113060526 113117076

CGIB:

127933497 127976698

PTET:

122361927(coq6)

LROH:

127179364(coq6)

OMC:	131523770(coq6)

PPRM:

120476045(coq6)

RKG:	130080193(coq6)

MAMB:

125269014(coq6)

CIDE:

127499225

CERY:

137006557(coq6)

MASI:

127411327 127454869

TROS:

130560744(coq6)

TDW:	130436497(coq6)

MANU:

129417633(coq6)

PDAB:

135778165(coq6)

IPU:

108270388

IFU:	128612502(coq6)

PHYP:

113538696(coq6)

SMEO:

124390036(coq6)

TFD:	113659582(coq6)

TVC:	132852576(coq6)

CGAR:

128535905(coq6)

NGRA:

132894434(coq6)

TRN:	134325444(coq6)

AMEX:

125781037(coq6)

CMAO:

118823387(coq6)

EEE:	113587022(coq6)

CHAR:

105908610(coq6)

SPIL:

134067417(coq6)

TRU:	101067224(coq6)

TFS:	130540226(coq6)

TNG:	GSTEN00032295G001

LCO:	104921380(coq6)

NCC:	104960922(coq6)

TBEN:

117478107(coq6)

CGOB:

115027301(coq6)

PGEO:

117468005(coq6)

GACU:

117550209(coq6)

EMAC:

134881845(coq6)

ELY:	117266992(coq6)

EFO:	125901098(coq6)

PLEP:

121953908(coq6)

SLUC:

116035569(coq6)

ECRA:

117935790(coq6)

ESP:	116669692(coq6)

PFLV:

114547214(coq6)

GAT:	120833329(coq6)

PPUG:

119227183(coq6)

AFB:	129103346(coq6)

CLUM:

117751449(coq6)

PSWI:

130201349(coq6)

CANA:

137787511(coq6)

CVE:	137869539(coq6)

MSAM:

119910219(coq6)

SCHU:

122861428(coq6)

CUD:	121526171(coq6)

SPUL:

138591042(coq6)

LMIX:

132992852(coq6)

ALAT:

119005049(coq6)

ASTR:

137611434(coq6)

MZE:	101482473(coq6)

ONL:	100708551(coq6)

OAU:	116335856(coq6)

OLA:	101164858(coq6)

OML:	112146146(coq6)

CSAI:

133462871(coq6)

XMA:	102227243(coq6)

XCO:	114134106(coq6)

XHE:	116708840(coq6)

PRET:

103459022(coq6)

PFOR:

103136189(coq6)

PLAI:

106961554(coq6)

PMEI:

106932880(coq6)

GAF:	122846421(coq6)

PPRL:

129365411(coq6)

CVG:	107092376(coq6)

CTUL:

119787572(coq6)

GMU:	124855448(coq6)

NFU:	107392376(coq6)

KMR:	108232568(coq6)

ALIM:

106520753(coq6)

NWH:	119427759(coq6)

AOCE:

111583159(coq6)

EJA:	138199880(coq6)

BFRE:

138630551(coq6)

MCEP:

125023426(coq6)

CSEM:

103397306(coq6)

POV:	109627765(coq6)

SSEN:

122782666(coq6)

SSOE:

131444608(coq6)

HHIP:

117755948(coq6)

HSP:	118116411(coq6)

PPLT:

128451376(coq6)

SMAU:

118285872(coq6)

LCF:

108892558

SDU:	111225565(coq6)

SLAL:

111663169(coq6)

XGL:	120795814(coq6)

HCQ:	109513213(coq6)

SSCV:

125980821(coq6)

SBIA:

133513631(coq6)

PEE:	133413091(coq6)

PTAO:

133487813(coq6)

BPEC:

110155522(coq6)

ENY:	140370184(coq6)

MALB:

109955088(coq6)

BSPL:

114848244(coq6)

SJO:	128375188(coq6)

SSCO:

134000580(coq6)

GMH:	115544164(coq6)

SASA:

100196727(coq6)

STRU:

115162306(coq6)

OTW:	112256713(coq6)

OMY:	110505567(coq6)

OGO:	124001114 124046476(coq6)

ONE:

115138525

OKI:

109904067

OKE:	118362514 118368286(coq6)

OMM:	135525854(coq6)

OCLA:

139383482

SALP:

111963298

SNH:	120023635(coq6)

CCLU:

121544891(coq6)

ELS:	105026441(coq6)

OEP:	134026935(coq6)

SFM:	108941514(coq6)

PKI:	111852430(coq6)

AANG:

118212628(coq6)

AROT:

135251367(coq6)

CCOG:

133129453(coq6)

LOC:	102691806(coq6)

PSPA:

121324831

ARUT:

117409082 117422049

PSEX:

120518791(coq6)

LCM:	102357129(COQ6)

CMK:	103186792(coq6)

RTP:	109927024(coq6)

CPLA:

122553383(coq6)

HOC:	132818407(coq6)

LERI:

129700018(coq6)

PMRN:

116939560(COQ6)

LRJ:	133347186(COQ6)

BFO:

118410281

BBEL:

109469941

CIN:

100175080

SCLV:

120326158

SPU:

576995

LPIC:

129264410

APLC:

110978170

ARUN:

117300529

AAMU:

139941732

AFIL:

140152432

AJC:

117107735

SKO:

100367074

PFLL:

139149194

DME:	Dmel_CG7277(Coq6)

DER:

6542443

DSE:

6613489

DSI:	Dsimw501_GD22648(Dsim_GD22648)

DYA:	Dyak_GE18996

DAN:

6497570

DSR:

110187410

DPO:

4818009

DPE:

6593707

DMN:

108161828

DWI:

6642635

DGR:

6562735

DMO:	Dmoj_GI21908

DAZ:

108611331

DNV:

108649630

DHE:

111599199

DVI:	6628181(Coq6)

CCAT:

101458940

BOD:

106627610

BDR:

105230774

RZE:

108366751

AOQ:

129246855

ALUD:

128863017

TDA:

119689485

MDE:

101899807

SCAC:

106083065

LCQ:

111681678

LSQ:

119604743

CVJ:	135950097(Coq6)

GFS:

119633690

ECOE:

129939477

CLON:

129611879

HIS:

119651456

AGA:

1272163

ACOZ:

120952377

AARA:

120905901

AMER:

121591053

ASTE:

118505296

AMAP:

126557602

AFUN:

125763249

AMOU:

128306379

AMRS:

128713816

AALI:

118456769

ACOS:

131268729

AAG:

5564252

AALB:

109431185

ASUA:

134207741

CQU:	CpipJ_CPIJ010620

CPII:

120413715

CNS:

116337368

BCOO:

119070612

LLL:

129788417

PPAP:

129809262

ACER:

107998942

ALAB:

122715363

ADR:

102673571

AFLR:

100872344

BIM:

100745177

BBIF:

117205058

BVK:

117231009

BVAN:

117155631

BHUN:

126871728

BTER:

105665756

BAFF:

126922322

BPYO:

122567927

BPAS:

132913040

FVI:

122529047

CCAL:

108622830

OBB:

114878727

OLG:

117602962

MGEN:

117221403

NMEA:

116423966

CGIG:

122398873

SOC:

105204785

MPHA:

105835945

AEC:

105147733

ACEP:

105620357

PBAR:

105422315

VEM:

105565812

COBS:

139111939(Coq6)

TLN:	139822461(Coq6)

HST:

105191106

CFO:

105254578

FEX:

115234458

PMEC:

138941396(Coq6)

PGC:

109856796

OBO:

105278861

PCF:

106790956

PFUC:

122519600

VPS:

122630539

VCRB:

124424240

VVE:

124950418

NVI:

100679257

CSOL:

105368107

TPRE:

106658097

LHT:

122506890

LBD:

127276685

MDL:

103575537

CGLO:

123262837

FAS:

105272091

DAM:	107041716 107043164

AGIF:

122855927

CINS:

118065618

VCAN:

122410090

CCIN:

112494071

DSM:

124414172

NLO:

107216898

NVG:

124309374

AROA:

105691808

TMOL:

138124723(Coq6)

DPA:

109543548

ESIM:

136410710

EFOR:

136344726(Coq6)

SOY:

115887911

AGRG:

126736228

ATD:

109608287

CSET:

123307189

HAXR:

123677701

AGB:

108909497

DVV:

114333072

NVL:

108556788

APLN:

108735116

OTU:

111415045

BMOR:

101746083

BMAN:

114247814

MSEX:

115444997

DPL:	KGM_211239

BANY:

112051368

MJU:

123874784

NIQ:

126775799

VCD:

124538188

MCIX:

123662099

PMAC:

106721652

PPOT:

106101172

PXU:

106120219

BPHI:

137919850(Coq6)

PRAP:

110994061

PBX:

123718436

PNAP:

125054472

ZCE:

119828563

CCRC:

123699537

LSIN:

126972416

AAGE:

121725875

HAW:

110379099

HZE:

124640072

TNL:

113499099

SLIU:

111350267

OFU:

114352587

ONU:

135080874

ATRA:

106130203

GMW:

113519609

PGW:

126375020

LGLY:

125233012

CSTB:

134748303

CCRN:

123292017

API:	100165758 100574105

DNX:

107163514

AGS:

114127453

RMD:

113560332

ACOO:

126834076

DVT:

126904628

BTAB:

109035008

CLEC:

106661011

HHAL:

106680657(Coq6)

NLU:

111048784

HVI:

124370772

MQU:

128983026

PHU:	Phum_PHUM546620

FOC:

113207620

TPAL:

117646631

ZNE:

110840710

CSEC:

111870342

BROR:

134530056

IEL:

124167846

HAMR:

139698913(Coq6)

FCD:

110844117

DPX:	DAPPUDRAFT_217996

DMK:	116935476 123470200

DPZ:

124338152

AFRA:

136029103

PJA:

122253725

PCHN:

125033401

HAME:

121864185 121872763

CQD:	128691115(Coq6)

PTRU:

123506090

ESN:

127005105

MNZ:

135215076

MRJ:	136836052(Coq6)

PORN:

139765288(Coq6)

LSM:	121127947(Coq6)

TCF:

131877854

PPOI:

119107692

DSV:

119458323

RSAN:

119373545

RMP:

119167407

VDE:

111244685

VJA:

111270442

DPTE:

113792336

DFR:

124495225

CSCU:

111642124

CVS:	136988125(Coq6)

PTEP:

107453780

ABRU:

129957684

UDV:

129222194

SDM:

118187849

LPOL:

106465323

PMEO:

129587403

CEL:	CELE_K07B1.2(coq-6)

CBR:	CBG_19254(Cbr-coq-6)

CRQ:	GCK72_017045

NAI:	NECAME_11645

TSP:

Tsp_07778

HRO:	HELRODRAFT_121890

LGI:	LOTGIDRAFT_224896

PVUL:

126820311

PCAN:

112570648

LSAX:

138952447

BGT:

106057054

GAE:

121372723

HRF:

124146637

HRJ:

124267155

HASI:

137293444

HCRA:

139442928

CRG:

105345345

CANU:

128175869

CVN:

111130282

OED:

125652414

MYI:

110456700

PMAX:

117323983

AIRR:

138319352

MCAF:

127738104

MMER:

123530976

RPHI:

132730340

DPOL:

127875109

MAEA:

128209922

OBI:

106874259

OSN:

115217341

LJP:

135468315

LAK:

106166695

SMM:	Smp_153460

SHX:	MS3_00003848(COQ6_1)

EGL:

EGR_02367

LLON:

135484065

NVE:

5515991

EPA:

110243806

ATEN:

116287572

ADF:

107356668

AMIL:

114966280

MCAZ:

138025993

MFOO:

137979556

PDAM:

113678605

SPIS:

111324894

DGT:

114522261

XEN:

124443095

HMG:

100211017

HSY:

130657169

RES:

135689808

TAD:	TRIADDRAFT_33826

AQU:

100634129

ATH:

AT3G24200

ALY:

9319544

CRB:

17893204

CSAT:

104746921 104766319 104789056

EUS:	EUTSA_v10002522mg

BRP:

103828683

BNA:	106445454 106453309 125575143

BOE:	106292435 106305627

RSZ:

108862843

THJ:

104821613

CPAP:

110813966

CIT:

102630098

CIC:	CICLE_v10004754mg

PVY:

116143039

MINC:

123220514

TCC:

18602777

GRA:

105800352

GHI:	107890577 107942321

GAB:

108454263

HSYR:

120194420 120197866 120213757

DZI:	111279946 111307889

EGR:

104456051

RARG:

115743325

GMX:

100807800

GSJ:

114423683

PVU:

137824249

VRA:

106759500

VAR:

108329787

VUN:	114183228 114183266 114184555 114192363 114194903

VUM:

124846829

CCAJ:

109811030

APRC:

113849204

MTR:	11427532 11446703

TPRA:

123889842

CAM:

101509373

PSAT:

127127831

VVO:	131609204 131628325

LJA:	130718140 130729418

ADU:	107484535 107485197

AIP:	107639529 107639614

AHF:	112743551 112743803 112796932 112797148

LANG:

109352513 109360677

PCIN:

129309443

QSA:	O6P43_003046

FVE:

101298602

AANS:

126794415

RCN:

112178512

PPER:

18777467

PMUM:

103337611

PAVI:

110762208

PDUL:

117628050

MDM:

103451859

MSYL:

126598321 126626869

PXB:

103927298

PCOX:

137711687

ZJU:

107430222

MNT:

21386624

CSAV:

115716151

CSV:

101214174

CMO:

103493132

BHJ:

120083310

MCHA:

111008170

CMAX:

111483410

CMOS:

111437650

CPEP:

111810688

RCU:

8280858

MEAN:

126669154

JCU:

105650370

HBR:

110641348

MESC:

110612007

POP:

7496073

PEU:

105132588

PALZ:

118061470

PNZ:

133680873

JRE:

108995891

CILL:

122300291

CAVE:

132179199

AGLU:

133872584

QSU:	112012694 112018019

QLO:

115960078

TWL:

120013600

VVI:

100248856

VRI:

117911732

SLY:

101257707

SPEN:

107030955

SOT:

102581687

SSTN:

125870386

SDUL:

129883241

CANN:

107864271

LBB:

132610219

NTA:

107821407

NSY:

104240762

NTO:

104112953

NAU:

109214282

INI:	109161592 109184365

ITR:

116028855

SIND:

105171855

OEU:

111381106

EGT:

105964203

SSPL:

121796006 121799714

SMIL:

130991831

SHIS:

125196111

APAN:

127261752

HAN:

110883809

ECAD:

122584716

LSV:

111882085

CCAV:

112511258

DCR:

108202878

CSIN:

114322146

RVL:

131300399

AEW:	130775782 130782941

DLT:

127812191

BVG:

104908709

SOE:

110774757

CQI:	110687915 110726768

ATRI:

130827897

MOF:

131152154

NNU:

104609186

MING:

122091565

TSS:

122667619

PSOM:

113283055 113296811

OSA:

4334721

DOSA:

Os03g0839100

OBR:

102701072

OGL:

127766978

BDI:

100823739

ATS:

109774650

TDC:	119287512 119312720

TAES:

123084128 123087733 123114196 123123683

TUA:

125553070

LPER:

127291880

LRD:	124680440 124680441

SBI:

8080177

ZMA:

100382613

MFLO:

136480400 136504749 136532854

SITA:

101778770

SVS:

117837527

PVIR:

120649158 120692270

PHAI:

112875176

PAUA:

133913740 133915047

PDA:	103702642 120109002

EGU:

105036774

MUS:

103986377

ZOF:	122010401 122016950

DCT:

110105097

PEQ:

110026365

AOF:

109837906

MSIN:

131245715

ACAK:

137962513

NCOL:

116252065

ATR:

18444040

CJF:

131060082

SMO:	SELMODRAFT_230657 SELMODRAFT_234128

PPP:

112277930

CRE:	CHLRE_02g112850v5

VCN:	VOLCADRAFT_42415

CSL:	COCSUDRAFT_36009

CVR:	CHLNCDRAFT_49348

OLU:	OSTLU_88383

OTA:	OT_ostta10g00780

BPG:	Bathy11g00810

MIS:	MICPUN_83519

MPP:	MICPUCDRAFT_50495

CME:	CYME_CMQ068C

GSL:	Gasu_55330

CCP:	CHC_T00006372001

SCE:	YGR255C(COQ6)

SEUB:

DI49_2219

SPAO:

SPAR_G04640

AGO:	AGOS_AFR648W

ERC:

Ecym_1120

KLA:	KLLA0_C02761g

KMX:	KLMA_10125(COQ6)

LTH:	KLTH0F02860g

VPO:	Kpol_2000p43

ZRO:	ZYRO0F16192g

CGR:	2887765(GVI51_F07799)

NCS:	NCAS_0E00580(NCAS0E00580)

NDI:	NDAI_0I02990(NDAI0I02990)

TPF:	TPHA_0B04290(TPHA0B04290)

TBL:	TBLA_0A05650(TBLA0A05650)

TGB:	HG536_0B01210

TDL:	TDEL_0C05980(TDEL0C05980)

KAF:	KAFR_0F04240(KAFR0F04240)

KNG:	KNAG_0B00490(KNAG0B00490)

ZMK:	HG535_0A01210

SLUD:

SCDLUD_003914

DHA:	DEHA2E14740g

PIC:	PICST_32861(COQ6)

PGU:	PGUG_05650

SPAA:

SPAPADRAFT_58061

LEL:	PVL30_001527(COQ6)

LBG:	92208054(LODBEIA_P28580)

CAL:	CAALFM_C103550CA(COQ6)

CTP:	CTRG_04559

COT:	CORT_0B09870

CDU:	CD36_03340

CTEN:

18248019(COQ6)

CLU:	CLUG_03437

CLUS:

A9F13_01g07469

CAUR:

CJI96_0003124

ASAU:

88174326(PUMCH_003262)

PPA:	PAS_chr2-2_0303

PKZ:	C5L36_0B03390

BNN:	FOA43_004473

BBRX:

BRETT_002288

OPA:	HPODL_02555

YLI:	2906060(YALI2_A00555g)

SLB:	AWJ20_3931(COQ6)

NCR:

NCU02536

NTE:	NEUTE1DRAFT92167(NEUTE1DRAFT_92167)

SMP:	10803667(SMAC4_05826)

PAN:	PODANSg10142

PBEL:

QC761_108640(COQ6)

PPSD:

QC762_108640(COQ6)

PPSP:

QC763_108640(COQ6)

PPSA:

QC764_108640(COQ6)

TTT:	THITE_2114052

MTM:	MYCTH_2313562

CTHR:

CTHT_0057100

RTHE:

98123328(VTJ83DRAFT_2416)

MGR:

MGG_11732

PPEI:

PpBr36_07625

TMN:	UCRPA7_1235

SSCK:

SPSK_05189

FGR:	FGSG_00375

FPU:	FPSE_00036

FPOA:

FPOAC1_000395

FVN:	FVRRES_00533

FVR:	FVEG_00830

FOX:	FOXG_00681

NHE:	NECHADRAFT_65697

FFC:	NCS54_00113800

FKR:	NCS57_00111900

FMU:	J7337_001163

TRE:	TRIREDRAFT_46301

TRR:	M419DRAFT_107643

TATV:

25775941(TrAtP1_004382)

TASP:

36617614(TrAFT101_003846)

MAW:	19253117(COQ6_1)

MAJ:

MAA_04321

MBRN:

26240490(coq6)

PCHM:

VFPPC_00277

CMT:

CCM_02264

AMUS:

LMH87_003951

PLJ:	28887336(PLICBS_002595)

PTKZ:

JDV02_001262(COQ6)

VAL:	VDBG_04706

VDA:	VDAG_04248

CFJ:	CFIO01_04948

CLUP:

CLUP02_05253

CHIG:

CH63R_00425

CDET:

87939124(CDEST_02621)

SAPO:

SAPIO_CDS3589

ELA:	UCREL1_5432

PFY:	PFICI_01114

SSL:	SS1G_10019

BFU:	BCIN_07g04710(Bccoq6)

MBE:

MBM_02434

PSCO:

LY89DRAFT_680425

GLZ:	GLAREA_00812

ANI:	ANIA_03586

AFM:	AFUA_4G12930

ACT:	ACLA_051920

NFI:	NFIA_103410

AOR:	AO090009000294

ANG:	An01g08500

AFV:	AFLA_011065

ALUC:

AKAW2_20903A(COQ6)

ACHE:

ACHE_10338A(COQ6)

APUU:

APUU_60287A(COQ6)

PCS:	N7525_005915

PDP:	PDIP_44590

POU:	POX_a01616

TMF:	EYB26_005185

TRG:	TRUGW13939_02648

CIM:	CIMG_00622

CPW:	9691877(COQ6)

URE:	UREG_00625

ABE:

ARB_00134

TVE:

TRV_00137

PBL:	PAAG_07027

PBN:	PADG_01557

BGH:	BDBG_02240

PNO:	SNOG_04759

PTE:

PTT_09914

PTRR:

6350260(PtrM4_142040)

BZE:	COCCADRAFT_93821

BSC:	COCSADRAFT_37897

BOR:	COCMIDRAFT_31795

AALT:

CC77DRAFT_933621

ADAC:

96086848(ACET3X_006526)

ARAB:

EKO05_0002208

ZTR:	MYCGRDRAFT_93579

PFJ:	MYCFIDRAFT_34240

FFU:	CLAFUR5_08017

CBET:

CB0940_04212

BCOM:

BAUCODRAFT_110130

NPA:	UCRNP2_8694

TML:	GSTUM_00008757001

SPO:	2539672(coq6)

SOM:	SOMG_01412(coq6)

CNE:

CNI04030

CNB:

CNBH3840

CNG:	CNAG_04264

CGI:	CGB_H4020C

CDEU:

CNBG_2785

CDEP:

91085825(L203_101612)

KMG:	30166002(I203_103486)

KNE:	92181155(IAR55_003897)

TMS:	TREMEDRAFT_25006

TASA:

A1Q1_02822

CCAC:

CcaHIS019_0702570(COQ6)

TVS:	TRAVEDRAFT_148557

DSQ:	DICSQDRAFT_167176

PCO:	PHACADRAFT_178811

SHS:	STEHIDRAFT_121516

HIR:	HETIRDRAFT_478045

PSQ:	PUNSTDRAFT_101551

ADL:	AURDEDRAFT_88534

FME:	FOMMEDRAFT_16018

GTR:	GLOTRDRAFT_75410

RSX:	RhiXN_05166

LBC:	LACBIDRAFT_305494

CCI:	CC1G_00949

ABP:	AGABI1DRAFT36282(AGABI1DRAFT_36282)

ABV:	AGABI2DRAFT151612(AGABI2DRAFT_151612)

MPR:	MPER_08618

MRR:	Moror_14073

E1B28_007265

SCM:	SCHCO_02618497(SCHCODRAFT_02618497)

SLA:	SERLADRAFT_452605

WSE:	WALSEDRAFT_66740

WIC:	J056_004417

UMA:	UMAG_11797

PFP:	PFL1_02464

SGRA:

EX895_003302

MGL:

MGL_2841

MRT:

MRET_3437

MSYM:

MSY001_3073

PTRC:

PtA15_6A298

PSTR:

Pst134EA_003133

MLR:	MELLADRAFT_32404

RIE:	OCT59_012884

DDI:	DDB_G0291440(coq6)

DPP:	DICPUDRAFT_154588

DFA:	DFA_12089(coq6)

TPS:	THAPSDRAFT_267948

PIF:	PITG_14563

PSOJ:

PHYSODRAFT_562005

BLAC:

94346726(CCR75_002958)

SPAR:

SPRG_20007

» show all

Reference

1 [PMID:38425362]

Authors

Nicoll CR, Alvigini L, Gottinger A, Cecchini D, Mannucci B, Corana F, Mascotti ML, Mattevi A.

Title

In vitro construction of the COQ metabolon unveils the molecular determinants of coenzyme Q biosynthesis.

Journal

Nat Catal 7:148-160 (2024)
DOI:10.1038/s41929-023-01087-z

Other DBs

ExplorEnz - The Enzyme Database:

1.14.15.46

IUBMB Enzyme Nomenclature:

1.14.15.46

ExPASy - ENZYME nomenclature database:

1.14.15.46

BRENDA, the Enzyme Database:

1.14.15.46

LinkDB

DBGET integrated database retrieval system