A cytochrome P-450 (heme-thiolate) protein catalysing an oxidative reaction that does not incorporate oxygen into the product. Forms the methylenedioxy bridge of the protoberberine alkaloid cheilanthifoline by the oxidative ring closure of adjacent phenolic and methoxy groups of scoulerine. cf. EC 18.104.22.168, (S)-nandinine synthase, which catalyses a similar reaction at the other side of the (S)-scoulerine molecule, forming (S)-nandinine.
EC 22.214.171.124 created 1999 as EC 126.96.36.199, transferred 2002 to EC 188.8.131.52, modified 2016, transferred 2018 to EC 184.108.40.206