| Entry |
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| Name |
estradiol 6beta-monooxygenase;
estradiol 6beta-hydroxylase
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| Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
Miscellaneous
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| Sysname |
estradiol-17beta,hydrogen-donor:oxygen oxidoreductase (6beta-hydroxylating)
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| Reaction(IUBMB) |
estradiol-17beta + reduced acceptor + O2 = 6beta-hydroxyestradiol-17beta + acceptor + H2O [RN: R03086]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| History |
EC 1.14.99.11 created 1965 as EC 1.14.1.10, transferred 1972 to EC 1.14.99.11
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| Pathway |
| ec00140 | Steroid hormone biosynthesis |
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| Reference |
1 |
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| Authors |
Haines WJ. |
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| Title |
The biosynthesis of adrenal cortex hormones. |
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| Journal |
Recent Progr Hormone Res 7:255-305 (1952) |
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| Reference |
2 |
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| Authors |
Mueller GC, Rumney G. |
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| Title |
Formation of 6beta-hydroxy and 6-keto derivatives of estradiol-16-C14 by mouse liver microsomes. |
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| Journal |
J Am Chem Soc 79:1004-1005 (1957) |
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| Other DBs |
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| LinkDB |
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