| Entry |
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| Name |
superoxide reductase;
neelaredoxin;
desulfoferrodoxin
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| Class |
Oxidoreductases;
Acting on superoxide as acceptor;
Acting on superoxide as acceptor (only sub-subclass identified to date)
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| Sysname |
rubredoxin:superoxide oxidoreductase
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| Reaction(IUBMB) |
superoxide + reduced rubredoxin + 2 H+ = H2O2 + oxidized rubredoxin [RN: R05743]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme contains non-heme iron.
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| History |
EC 1.15.1.2 created 2001 as EC 1.18.96.1, transferred 2001 to EC 1.15.1.2
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| Orthology |
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| Genes |
| METY: | MRY16398_12390(rbo) |
| MDH: | AYM39_07550 AYM39_13650 |
| MKO: | MKLM6_1550 MKLM6_2799 |
| MESL: | KKZ03_07735 KKZ03_07955 |
| SAQT: | GJV85_05690 GJV85_05875 |
| SBA: | Sulba_1078 Sulba_1286 |
| SMUL: | SMUL_1334 SMUL_1620 |
| SHAL: | SHALO_1315 SHALO_1578 |
| SULS: | Sdiek1_0483 Sdiek1_1387 |
| SULJ: | SJPD1_0488 SJPD1_1320 |
| SULT: | FA592_09470 FA592_12860 |
| SINU: | IMZ28_05340 IMZ28_07280 |
| SMAB: | LN246_06130 LN246_08295 |
| NAP: | C3L23_00495 C3L23_02355 |
| CMED: | FE773_00510 FE773_03150 |
| CPAF: | C6V80_00455 C6V80_07575 |
| GEF: | FO488_13170 FO488_18880 |
| GSUB: | KP001_07775 KP001_11325 |
| GNT: | KP003_03875 KP003_10880 |
| GSB: | GSUB_13600 GSUB_15705 |
| DEP: | AOP6_2409(dfx) AOP6_2966 |
| DES: | DSOUD_0362 DSOUD_0985 |
| DSA: | Desal_0088 Desal_2678 |
| DHY: | DESAM_20639(dfx) DESAM_21841 |
| DEJ: | AWY79_05230 AWY79_12210 |
| DDN: | DND132_0426 DND132_1757 |
| EAQ: | LDFHOB_00040 LDFHOB_03735 |
| DHG: | EYB58_14370 EYB58_19645 |
| DWD: | DSCW_20160(dfx_1) DSCW_49810(dfx_2) |
| DVR: | Dvar_29330 Dvar_54720 Dvar_84630 |
| DTI: | Desti_2658 Desti_4277 |
| DMP: | FAK_02470 FAK_21170(dfx) |
| TAV: | G4V39_02435 G4V39_02440 |
| TMAI: | FVE67_06950 FVE67_08370 |
| BROC: | IPI25_00235 IPI25_14055 |
| JET: | L3J17_07500 L3J17_09870 |
| ALUS: | STSP2_01130 STSP2_02686(dfx) |
| SBU: | SpiBuddy_1683 SpiBuddy_1946 |
| SGP: | SpiGrapes_0076 SpiGrapes_3009 |
| SASS: | MUG09_09420 MUG09_10440 |
| THYD: | TTHT_1808(dfx) TTHT_1831 |
| SHYR: | LA303_07425 LA303_11860 |
| DTE: | Dester_0591 Dester_1255 |
| CEX: | CSE_12390(dfx) CSE_12400 |
| TVX: | QBE54_01785 QBE54_10880 |
| ATHO: | M15_17730 M15_22040 |
| CSR: | Cspa_c24390(dfx) Cspa_c24400 |
| CCK: | Ccar_10905 Ccar_17895 Ccar_18940 |
| CCOH: | SAMEA4530647_2158(dfx) |
| CFER: | D4Z93_10020 D4Z93_10995 |
| FTK: | PXT33_005890 PXT33_006105 |
| FAH: | MTP37_09545 MTP37_09720 |
| VFA: | MM35RIKEN_14000(rbo) MM35RIKEN_23700(rbo) |
| VCOP: | MM50RIKEN_15760(rbo) |
| ACOL: | K5I23_00950 K5I23_14285 |
| AGAT: | RWV98_00325 RWV98_05060 |
| DOR: | Desor_1729 Desor_4470 |
| DAI: | Desaci_0425 Desaci_2304 |
| AWI: | CHL1_002398 CHL1_003103 |
| BPRS: | CK3_07380 CK3_14460 |
| BPRO: | PMF13cell1_00460(dfx_1) PMF13cell1_02030(dfx_3) |
| BLIQ: | INP51_02625 INP51_14390 |
| LACY: | A4V08_05450 A4V08_08100 |
| CSCI: | HDCHBGLK_01585(dfx_1) |
| CSH: | Closa_2525 Closa_4054 |
| LXA: | OW255_01475 OW255_08410 |
| CBOL: | CGC65_18135 CGC65_20685 |
| ECLF: | QMP25_01355 QMP25_14090 |
| KIB: | RBB56_10560 RBB56_17370 |
| HHJ: | NQ487_00515 NQ487_29510 |
| LBX: | lbkm_1993 lbkm_2858 lbkm_4057 |
| PDF: | CD630DERM_08270(rbo) |
| PHX: | KGNDJEFE_00677(dfx_1) |
| TEX: | Teth514_0680 Teth514_0907 |
| TPD: | Teth39_0242 Teth39_0429 |
| TBO: | Thebr_0249 Thebr_0441 |
| TWI: | Thewi_2208 Thewi_2467 |
| TKI: | TKV_c15620 TKV_c22020(dfx) |
| THEZ: | OEI98_002420 OEI98_002687 |
| TPZ: | Tph_c07660 Tph_c08000(dfx) |
| MHW: | ACT01_02635 ACT01_06395 |
| MMAX: | LCQ47_07600 LCQ47_09370 |
| SGBI: | P3F81_00195 P3F81_00465 P3F81_03305 |
| MANA: | MAMMFC1_02699 MAMMFC1_03328 |
| SSID: | SPSIL_022580(dfx_1) SPSIL_032110 SPSIL_035180(dfx_2) |
| PFAC: | PFJ30894_02271(dfx) |
| AARG: | Aargi30884_29570(rbo) |
| ABSI: | A9CBEGH2_01700(rbo) |
| FIT: | Fi14EGH31_27910(rbo) |
| AHK: | NCTC10172_00138(dfx) |
| AFG: | AFULGI_00003430 AFULGI_00009190 |
| MMET: | MCMEM_0965 MCMEM_1494 MCMEM_1628 |
| MELO: | J7W08_02865 J7W08_06270 J7W08_07000 |
| MMH: | Mmah_0553 Mmah_0585 Mmah_1131 |
| MHAZ: | BHR79_00485 BHR79_00645 BHR79_07885 |
| MPOT: | BKM01_04030 BKM01_07765 BKM01_07920 |
| MEV: | Metev_0306 Metev_1346 |
| MMAV: | RE476_01030 RE476_09990 |
| MHZ: | Metho_0008 Metho_1865 |
| MEZ: | Mtc_1945(sor) Mtc_2431(dfx) |
| RCI: | RCIX1592(dfx) RCIX2624(sor) |
| LOKI: | Lokiarch_17190(dfx) |
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| Reference |
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| Authors |
Jenney FE Jr, Verhagen MF, Cui X, Adams MW |
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| Title |
Anaerobic microbes: oxygen detoxification without superoxide dismutase. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Yeh AP, Hu Y, Jenney FE Jr, Adams MW, Rees DC. |
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| Title |
Structures of the superoxide reductase from Pyrococcus furiosus in the oxidized and reduced states. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Lombard M, Fontecave M, Touati D, Niviere V |
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| Title |
Reaction of the desulfoferrodoxin from Desulfoarculus baarsii with superoxide anion. Evidence for a superoxide reductase activity. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Abreu IA, Saraiva LM, Carita J, Huber H, Stetter KO, Cabelli D, Teixeira M. |
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| Title |
Oxygen detoxification in the strict anaerobic archaeon Archaeoglobus fulgidus: superoxide scavenging by neelaredoxin. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.15.1.2 |
| ExPASy - ENZYME nomenclature database: | 1.15.1.2 |
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| LinkDB |
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