KEGG ENZYME: 1.16.2.1

ENZYME: 1.16.2.1

Entry

EC 1.16.2.1                 Enzyme

Name

iron---cytochrome-c reductase;
iron-cytochrome c reductase;
mtrC (gene name);
omcA (gene name);
omcB (gene name)

Class

Oxidoreductases;
Oxidizing metal ions;
With a cytochrome as acceptor

Sysname

ferrocytochrome-c:Fe3+ oxidoreductase

Reaction(IUBMB)

ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+ [RN:R05318]

Reaction(KEGG)

R05318

Substrate

ferrocytochrome c [CPD:C00126];
Fe3+ [CPD:C14819]

Product

ferricytochrome c [CPD:C00125];
Fe2+ [CPD:C14818]

Comment

The MtrC and OmcA proteins of the bacterium Shewanella oneidensis MR-1 are decaheme c-type cytochromes that reduce iron oxides extracellularly, passing the electrons to MtrA, another decaheme c-type cytochrome located in the periplasm.

History

EC 1.16.2.1 created 1972 as EC 1.9.99.1, transferred 2014 to EC 1.9.98.1, transferred 2024 to EC 1.16.2.1

Reference

1 [PMID:11169112]

Authors

Beliaev AS, Saffarini DA, McLaughlin JL, Hunnicutt D.

Title

MtrC, an outer membrane decahaem c cytochrome required for metal reduction in Shewanella putrefaciens MR-1.

Journal

Mol Microbiol 39:722-30 (2001)
DOI:10.1046/j.1365-2958.2001.02257.x

Sequence

[son:SO_1778]

Reference

2 [PMID:12904229]

Authors

Myers CR, Myers JM.

Title

Cell surface exposure of the outer membrane cytochromes of Shewanella oneidensis MR-1.

Journal

Lett Appl Microbiol 37:254-8 (2003)
DOI:10.1046/j.1472-765x.2003.01389.x

Reference

3 [PMID:17468239]

Authors

Lower BH, Shi L, Yongsunthon R, Droubay TC, McCready DE, Lower SK.

Title

Specific bonds between an iron oxide surface and outer membrane cytochromes MtrC and OmcA from Shewanella oneidensis MR-1.

Journal

J Bacteriol 189:4944-52 (2007)
DOI:10.1128/JB.01518-06

Sequence

[son:SO_1778 SO_1779]

Reference

4 [PMID:20018742]

Authors

Hartshorne RS, Reardon CL, Ross D, Nuester J, Clarke TA, Gates AJ, Mills PC, Fredrickson JK, Zachara JM, Shi L, Beliaev AS, Marshall MJ, Tien M, Brantley S, Butt JN, Richardson DJ.

Title

Characterization of an electron conduit between bacteria and the extracellular environment.

Journal

Proc Natl Acad Sci U S A 106:22169-74 (2009)
DOI:10.1073/pnas.0900086106

Reference

5 [PMID:22360295]

Authors

Mitchell AC, Peterson L, Reardon CL, Reed SB, Culley DE, Romine MR, Geesey GG.

Title

Role of outer membrane c-type cytochromes MtrC and OmcA in Shewanella oneidensis MR-1 cell production, accumulation, and detachment during respiration on hematite.

Journal

Geobiology 10:355-70 (2012)
DOI:10.1111/j.1472-4669.2012.00321.x

Reference

6 [PMID:32978123]

Authors

Jing X, Wu Y, Shi L, Peacock CL, Ashry NM, Gao C, Huang Q, Cai P.

Title

Outer Membrane c-Type Cytochromes OmcA and MtrC Play Distinct Roles in Enhancing the Attachment of Shewanella oneidensis MR-1 Cells to Goethite.

Journal

Appl Environ Microbiol 86:AEM.01941-20 (2020)
DOI:10.1128/AEM.01941-20

Other DBs

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