KEGG ENZYME: 1.2.99.7

ENZYME: 1.2.99.7

Entry

EC 1.2.99.7                 Enzyme

Name

aldehyde dehydrogenase (FAD-independent);
aldehyde oxidase;
aldehyde oxidoreductase;
Mop;
AORDd

Class

Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With unknown physiological acceptors

Sysname

aldehyde:acceptor oxidoreductase (FAD-independent)

Reaction(IUBMB)

an aldehyde + H2O + acceptor = a carboxylate + reduced acceptor [RN:R00544]

Reaction(KEGG)

R00544 > R00638

Substrate

aldehyde [CPD:C00071];
H2O [CPD:C00001];
acceptor [CPD:C00028]

Product

carboxylate [CPD:C00060];
reduced acceptor [CPD:C00030]

Comment

Belongs to the xanthine oxidase family of enzymes. The enzyme from Desulfovibrio sp. contains a molybdenum-molybdopterin-cytosine dinucleotide (MCD) complex and two types of [2Fe-2S] cluster per monomer, but does not contain FAD.

History

EC 1.2.99.7 created 2004

Orthology

K07469

aldehyde oxidoreductase

Genes

BCEW:

DM40_5295

BAM:

Bamb_5751

BAC:	BamMC406_5518

BDL:

AK34_5296

BPYR:

ABD05_31095

BLAT:

WK25_17150

BTEI:

WS51_26525

RGU:	A4W93_01525

SDL:

Sdel_1475

SMUL:

SMUL_2101

SHAL:

SHALO_1855

SULS:

Sdiek1_1939

SULJ:

SJPD1_1855

SULT:

FA592_01805

GUR:

Gura_0998

PCA:

Pcar_0220

PACE:

A6070_10775 A6070_14425

PEF:	A7E78_09400

PPD:

Ppro_1551

DVU:	DVU_1559(mop)

DVL:

Dvul_1574

DVM:

DvMF_0641

DVG:	Deval_1735

DDS:

Ddes_1823

DFI:	AXF13_03440

DPG:	DESPIGER_0125

DEF:	CNY67_03300

DSD:	GD606_04460

DMA:

DMR_05980

DCB:	C3Y92_17455

DGG:	DGI_0902(mop)

DDE:

Dde_3539

DMS:	E8L03_03670 E8L03_11880

DSA:	Desal_0299

DHY:	DESAM_20433(mop)

DAF:	Desaf_0413

DPI:	BN4_11183 BN4_11879(mop)

DEJ:	AWY79_13680

PPRF:

DPRO_1126(mop)

PSEL:

GM415_09125 GM415_15685

DDN:	DND132_0141

DSX:	GD604_04725

PBIZ:

LWC08_01190

DBA:

Dbac_1562

DOA:	AXF15_08755

DRT:

Dret_1808

DPS:

DP0270

DSF:

UWK_01309

DPR:	Despr_1636

DEO:	CAY53_03230 CAY53_03300

DOG:	HP555_04800

DAT:	HRM2_07080(mop1) HRM2_38770(mop2)

DTO:	TOL2_C39330(mop)

DOV:	DSCO28_12970(mop_1) DSCO28_16460(mop_2) DSCO28_22590 DSCO28_54420(mop_3)

DWD:	DSCW_31270(mop) DSCW_61540

DALK:

DSCA_49590(mop)

DLI:

dnl_22250

HOH:

Hoch_4147

DTI:	Desti_0720 Desti_1799

SFU:

Sfum_1310

MLN:	A9174_02930

MCI:	Mesci_0582

MOP:	Mesop_0592

MAM:	Mesau_00496

MAMO:

A6B35_05605

MESW:

A9K65_002925

MESM:

EJ066_08410

MESP:

C1M53_10270

MHUA:

MCHK_5950

MJR:	EB229_02985

MERD:

EB233_03085

MESR:

FGU64_20365

MESO:

BSQ44_15110

AAK:	AA2016_0465

AMIH:

CO731_00453(mop)

NIY:	FQ775_19710

BOS:	BSY19_2962

BVV:	BHK69_21675

LNE:	FZC33_27030

MET:

M446_1983

MNO:

Mnod_1247

MICO:

GDR74_16685

CHEL:

AL346_07265

CDQ:	BOQ54_00405

RBM:

TEF_05295

PHR:	C6569_02190

PSTG:

E8M01_20805

SUAM:

BOO69_08870

RID:	RIdsm_05003(mop)

ROH:	FIU89_19770(mop)

THAA:

CFI11_12465

RBL:	B6K69_01545

TAW:	EI545_19705

SALO:

EF888_04490

PAED:

G5B38_12200

THAS:

C6Y53_07615

RAP:	RHOA_5093(mop)

FER:	FNB15_14110

HTQ:	FRZ44_34540

HADH:

FRZ61_33730

LCY:	LC20004_04335

EFL:

EF62_2740

EFI:	OG1RF_11951

EFD:	EFD32_2139

EFS:

EFS1_2048

EFN:	DENG_02507

EFQ:

DR75_1278

ENE:

ENT_17490

ESS:	ATZ33_06975

CLJ:	CLJU_c24050 CLJU_c24130

CLS:	CXIVA_04850(CoxL)

CSR:	Cspa_c06890(mop1)

CAH:	CAETHG_0471

CSQ:

CSCA_3243

CCK:	Ccar_24780

CTYK:

CTK_C17200

CEU:	A7L45_05835

CFM:	BJL90_11360

CDRK:

B9W14_03710

CDY:	F3K33_02770(xdh)

CGAS:

J1C67_15775(xdh)

CLOS:

DMR38_12345 DMR38_12385

GFE:	Gferi_19165

RUM:

CK1_27440

OVA:	OBV_43650(mop)

CCT:

CC1_17680

ROB:

CK5_22910

BYL:	A4V09_21845

BPRO:

PMF13cell1_01056(mop_1)

BLAB:

EYS05_07740

LACY:

A4V08_07960

CSCI:

HDCHBGLK_02491(pucD)

CSH:	Closa_0937

ACAC:

EYQ97_05565(xdh)

LUA:	D4A81_03745(xdh)

ACEL:

acsn021_14170

RTO:

RTO_09230

RGN:	RGna_16200(xdh)

CBOL:

CGC65_06510

PDC:	CDIF630_03469(xdhA5)

CDC:	CD196_2987(xdhA3)

CDL:	CDR20291_3033(xdhA3)

PDF:	CD630DERM_31770

ROC:	HF520_00005(xdh)

TEM:	JW646_03490

TGC:	L0P85_04810

TEB:	T8CH_1499(mop)

DSY:	DSY0872 DSY1987

DHD:

Dhaf_3146

DDH:	Desde_2603

DOR:	Desor_1273 Desor_3016

DAI:	Desaci_2677 Desaci_2707

DMI:	Desmer_1171 Desmer_1863

DCA:	Desca_1570

PTH:

PTH_0679

DRU:	Desru_0522

DFG:	B0537_02740

DAE:

Dtox_3440

FWA:	DCMF_02040 DCMF_08470 DCMF_14090 DCMF_14115 DCMF_21835 DCMF_26870

DGI:	Desgi_0268 Desgi_0270 Desgi_2922 Desgi_3899

ELM:

ELI_2450

EMT:	CPZ25_004590(xdh)

ELIM:

B2M23_18880

AWO:	Awo_c03890(mop1) Awo_c14980(mop3) Awo_c27190

AWI:	CHL1_002337

VGU:	HYG85_23235(xdh)

VPY:	HZI73_14850(xdh)

IBU:	IB211_02864c

AVG:	I6H45_07650(xdh)

AOB:	I6H46_01605(xdh)

MED:

MELS_0607

MHW:	ACT01_13630

MMAX:

LCQ47_07125(xdh)

PFT:

JBW_01067

STED:

SPTER_09650(mop)

PBF:	CFX0092_B0235

BHY:	BHWA1_00070(coxL)

BHD:	BHYOB78_02635

BRM:

Bmur_2657

BPO:	BP951000_0728

BPJ:	B2904_orf2108(coxL)

BPIP:

BPP43_11515

BPW:	WESB_2048(coxL)

BIP:

Bint_1931

BHP:	BHAMNSH16_01320

FVA:	FV113G1_27980

FUL:	C4N20_09745(xdh)

FMO:	C4N19_00290(xdh)

LEO:	AMK43_04750

STR:	Sterm_3270

AMO:	Anamo_0983 Anamo_1057

CPOR:

BED41_02500 BED41_02975 BED41_11740

TTZ:	FHG85_06335(xdh)

BLQ:	L21SP5_02720(mop)

» show all

Reference

1 [PMID:14659539]

Authors

Uchida H, Kondo D, Yamashita A, Nagaosa Y, Sakurai T, Fujii Y, Fujishiro K, Aisaka K, Uwajima T.

Title

Purification and characterization of an aldehyde oxidase from Pseudomonas sp. KY 4690.

Journal

FEMS Microbiol Lett 229:31-6 (2003)
DOI:10.1016/S0378-1097(03)00781-X

Reference

2 [PMID:10679276]

Authors

Duarte RO, Archer M, Dias JM, Bursakov S, Huber R, Moura I, Romao MJ, Moura JJ

Title

Biochemical/spectroscopic characterization and preliminary X-ray analysis of a new aldehyde oxidoreductase isolated from Desulfovibrio desulfuricans ATCC 27774.

Journal

Biochem Biophys Res Commun 268:745-9 (2000)
DOI:10.1006/bbrc.2000.2135

Reference

3 [PMID:10727945]

Authors

Andrade SL, Brondino CD, Feio MJ, Moura I, Moura JJ

Title

Aldehyde oxidoreductase activity in Desulfovibrio alaskensis NCIMB 13491 EPR assignment of the proximal [2Fe-2S] cluster to the Mo site.

Journal

Eur J Biochem 267:2054-61 (2000)
DOI:10.1046/j.1432-1327.2000.01209.x

Reference

4 [PMID:7502041]