Entry |
|
Name |
UDP-N-acetylmuramate dehydrogenase;
MurB reductase;
UDP-N-acetylenolpyruvoylglucosamine reductase;
UDP-N-acetylglucosamine-enoylpyruvate reductase;
UDP-GlcNAc-enoylpyruvate reductase;
uridine diphosphoacetylpyruvoylglucosamine reductase;
uridine diphospho-N-acetylglucosamine-enolpyruvate reductase;
uridine-5'-diphospho-N-acetyl-2-amino-2-deoxy-3-O-lactylglucose:NADP-oxidoreductase
|
Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
|
Sysname |
UDP-N-acetyl-alpha-D-muramate:NADP+ oxidoreductase
|
Reaction(IUBMB) |
UDP-N-acetyl-alpha-D-muramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH + H+ [RN: R03192]
|
Reaction(KEGG) |
|
Substrate |
UDP-N-acetyl-alpha-D-muramate [CPD: C01050];
NADP+ [CPD: C00006]
|
Product |
UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine [CPD: C04631];
NADPH [CPD: C00005];
H+ [CPD: C00080]
|
Comment |
A flavoprotein (FAD). NADH can to a lesser extent replace NADPH.
|
History |
EC 1.3.1.98 created 1976 as EC 1.1.1.158, modified 1983, modified 2002, transferred 2013 to EC 1.3.1.98
|
Pathway |
ec00520 | Amino sugar and nucleotide sugar metabolism |
|
Orthology |
K00075 | UDP-N-acetylmuramate dehydrogenase |
|
Genes |
ECOO: | ECRM13514_5092(murB) |
ECOH: | ECRM13516_4828(murB) |
ELR: | ECO55CA74_22935(murB) |
ECW: | EcE24377A_4511(murB) |
EDJ: | ECDH1ME8569_3836(murB) |
ECOI: | ECOPMV1_02817(murB) |
SEM: | STMDT12_C42790(murB) |
SEEH: | SEEH1578_06900(murB) |
SENJ: | CFSAN001992_13035(murB) |
SENC: | SEET0819_04495(murB) |
REE: | electrica_04838(murB) |
RTG: | NCTC13098_06961(murB) |
CLAP: | NCTC11466_04372(murB) |
KIE: | NCTC12125_03540(murB) |
AHN: | NCTC12129_04695(murB_1) |
METY: | MRY16398_53900(murB) |
PTF: | PROFFT_A_00680(murB) |
PSHI: | SAMEA2665130_2801(murB) |
YPG: | YpAngola_A3397(murB) |
YPI: | YpsIP31758_3872(murB) |
SMW: | SMWW4_v1c02690(murB) |
SFJ: | SAMEA4384070_0246(murB) |
SOF: | NCTC11214_02068(murB) |
SSAR: | SSARUM_000227(murB) |
SERA: | Ser39006_002425(murB) |
PAQU: | DMB82_0000920(murB) |
PPAV: | LOZ86_01910(murB) LOZ86_07055 |
PARL: | PEC302110_37740(murB) |
DIC: | Dpoa569_000189(murB) |
EHD: | ERCIPSTX3056_317(murB) |
BAPF: | BUMPF009_CDS00545(murb) |
BAPG: | BUMPG002_CDS00546(murb) |
BAPU: | BUMPUSDA_CDS00544(murb) |
BAPW: | BUMPW106_CDS00545(murb) |
TPTY: | NCTC11468_00172(murB) |
PRG: | RB151_042930(murB_1) |
PHEI: | NCTC12003_03812(murB) |
PRJ: | NCTC6933_03833(murB) |
LRI: | NCTC12151_03329(murB) |
HIC: | NTHIC486_00725(murB) |
HPIT: | NCTC13334_00226(murB) |
HHZ: | NCTC10839_00243(murB) |
HAEG: | NCTC8502_00957(murB) |
PDAG: | 4362423_01701(murB) |
ADP: | NCTC12871_01126(murB) |
ALIG: | NCTC10568_02247(murB_1) |
ASEG: | NCTC10977_00386(murB) |
AVT: | NCTC3438_00228(murB) |
RPNE: | NCTC8284_00998(murB_1) |
PAET: | NCTC13378_01548(murB) |
XFU: | XFF4834R_chr19330(murB) |
XPH: | XppCFBP6546_19335(murB) |
XHD: | LMG31886_25030(murB) |
LLZ: | LYB30171_01016(murB) |
VAU: | VANGNB10_cI0200(murB) |
VGI: | MID13_01075(murB) MID13_14745(murB) |
VPL: | SA104470976_02409(murB) |
VIB: | VspSTUT11_01090(murB) |
VIS: | VspSTUT16_01270(murB) |
PAEB: | NCGM1900_3329(murB) |
PVD: | CFBP1590__3822(murB) |
PPRC: | PFLCHA0_c18190(murB) |
PFC: | PflA506_3148(murB_1) PflA506_4590(murB_2) |
PMUD: | NCTC8068_01445(murB) |
PFW: | PF1751_v1c31830(murB) |
PPUU: | PputUW4_04047(murB) |
PTRT: | HU722_0017690(murB) |
PTW: | TUM18999_18420(murB) |
PTAE: | NCTC10697_01228(murB) |
PCUC: | PSH97_10730 PSH97_20705(murB) |
MSHE: | MAALD49_17490(murB) MAALD49_25820(murB1) |
MNK: | RE428_05470(murB_1) RE428_21480(murB_2) |
PSYC: | DABAL43B_1344(murB) |
MCAT: | MC25239_00704(murB) |
MCUN: | NCTC10297_01756(murB) |
SHP: | Sput200_0148 Sput200_2701 |
SCAA: | TUM17387_01790(murB) |
PSYM: | J1N51_03855 J1N51_08555(murB) |
AMAL: | I607_07540 I607_16605 |
AMAE: | I876_07800 I876_16915 |
AMAO: | I634_07915 I634_16845 |
SALH: | HMF8227_00416(murB) |
CBS: | COXBURSA331_A0226(murB) |
LLG: | 44548918_02410(murB) |
LJR: | NCTC11533_02577(murB) |
LCJ: | NCTC11976_03317(murB) |
LWA: | SAMEA4504053_3100(murB) |
LSS: | NCTC12082_01752(murB) |
LADL: | NCTC12735_00969(murB) |
LANT: | TUM19329_06130(murB_1) TUM19329_15130(murB_2) |
MISZ: | MishRS11D_06340(murB) |
TIB: | THMIRHAM_12380(murB) |
TSE: | THMIRHAS_12130(murB) |
TZO: | THMIRHAT_12560(murB) |
TLR: | Thiosp_00566(murB_1) Thiosp_04637(murB_2) |
TFRI: | Thiofri_04393(murB) |
TNI: | TVNIR_2602(murB_[H]) |
GAI: | IMCC3135_22295(murB) |
THIC: | TspCOW1_31510(murB) |
HAHH: | O5O45_08565(murB) O5O45_13225(murB) |
HALO: | BWR19_10145 BWR19_12025 |
HAAH: | HALA3H3_950028(murB) |
HSR: | HSBAA_25140(murB) HSBAA_63530 |
HAA: | A5892_11135 A5892_13755 |
ALCA: | ASALC70_00366(murB) |
AEL: | NCTC12917_00231(murB) |
CHJ: | NCTC10426_02202(murB) |
CDIZ: | CEDIAZO_03482(murB) |
GPB: | HDN1F_05390(murB1) HDN1F_33180(murB2) |
NMM: | NMBM01240149_1280(murB) |
NMS: | NMBM01240355_0810(murB) |
NMQ: | NMBM04240196_1354(murB) |
NMZ: | NMBNZ0533_0859(murB) |
NMX: | NMA510612_1143(murB) |
NWE: | SAMEA3174300_1196(murB) |
NZO: | SAMEA4504057_1145(murB) |
NCI: | NCTC10296_01140(murB) |
NCZ: | NCTC10294_00456(murB) |
NANI: | NCTC12227_00973(murB) |
ECOR: | SAMEA4412678_1274(murB) |
CNC: | CNE_1c30170(murB) CNE_BB1p03170(murB) |
BMV: | BMASAVP1_A0674(murB) |
BML: | BMA10229_A2509(murB) |
BPM: | BURPS1710b_1072(murB) |
BPL: | BURPS1106A_0920(murB) |
BCJ: | BCAL2768(murB) pBCA086 |
BUE: | BRPE67_ACDS22040(murB) |
PLG: | NCTC10937_01697(murB) |
LMIR: | NCTC12852_01431(murB) |
BUO: | BRPE64_ACDS22550(murB) |
VTR: | MYVALT_F_00960(murB) |
BTRM: | SAMEA390648700258(murB) |
AXX: | ERS451415_01201(murB) |
LIM: | L103DPR2_02344(murB) |
LIH: | L63ED372_00754(murB) |
SMIO: | CATMQ487_43630(murB) |
URU: | DSM104443_00680(murB) |
UPL: | DSM104440_00646(murB) |
THAG: | CKCBHOJB_03327(murB) |
FPHO: | SHINM1_017220(murB) |
RTT: | RTTH1527_01165(murB) |
RTB: | RTB9991CWPP_01170(murB) |
RBS: | RHODOSMS8_01894(murB) |
SMEL: | SM2011_c01868(murB) |
SFD: | USDA257_c44980(murB) |
SAME: | SAMCFNEI73_Ch2460(murB) |
AGR: | AGROH133_07426(murB) |
ALF: | CFBP5473_05545(murB) |
AVV: | RvVAT039_03500(murB) |
AVF: | RvVAR031_24180(murB) |
ASAL: | CFBP5507_09265(murB) |
RPUS: | CFBP5875_08900(murB) |
ALEG: | CFBP4996_08800(murB) |
REC: | RHECIAT_CH0002996(murB) |
REL: | REMIM1_CH02893(murB) |
REP: | IE4803_CH03070(murB) |
REI: | IE4771_CH03108(murB) |
RTR: | RTCIAT899_CH11350(murB) |
RGA: | RGR602_CH02494(murB-1) RGR602_PC01081(murB-2) |
RPHA: | AMC79_CH03008(murB) |
RLW: | RlegWSM1455_14365(murB) |
RBW: | RLCC275e_14400(murB) |
NEN: | NCHU2750_14860(murB) |
LAS: | CLIBASIA_04985(murB) |
BIO: | BR141012304_11283(murB) |
OCH: | CES85_1567 CES85_4940 |
BSEP: | HAP48_0002765(murB) |
BCAN: | BcanWSM471_29035(murB) |
VGO: | GJW-30_1_01846(murB) |
BHS: | BM1374165_01162(murB) |
BBK: | BARBAKC583_0945(murB) |
BTX: | BM1374166_01516(murB) |
BEZ: | NCTC12898_01028(murB) |
MAQU: | Maq22A_c12425(murB) |
MMES: | MMSR116_19940(murB) |
MTUN: | MTUNDRAET4_1810(murB) |
FIL: | BN1229_v1_3988(murB) |
FIY: | BN1229_v1_3975(murB) |
PEM: | OF122_02280(murB) OF122_07680(murB) OF122_14015(murB) |
MAAD: | AZF01_05785 AZF01_11385 |
MLUT: | JET14_07085(murB) JET14_11835(murB) |
TSV: | DSM104635_02817(murB) |
RLI: | RLO149_c025680(murB) |
PHP: | PhaeoP97_00933(murB) |
PPIC: | PhaeoP14_00885(murB) |
CID: | P73_3201(murB) P73_4315(murB) |
PABY: | Ga0080574_TMP1181 Ga0080574_TMP5029 |
SINL: | DSM14862_01105(murB) |
SPSE: | SULPSESMR1_01937(murB) |
RMM: | ROSMUCSMR3_01027(murB) |
AHT: | ANTHELSMS3_04265(murB) |
RMH: | LVO79_05790(murB) LVO79_11970(murB) |
LALG: | LentiSH36_01688(murB) |
LVS: | LOKVESSMR4R_01005(murB) |
HML: | HmaOT1_00420(murB) HmaOT1_04315(murB) |
LIT: | FPZ52_07295(murB) FPZ52_13925(murB) |
POZ: | I0K15_04800(murB) I0K15_10190(murB) |
AALK: | LGT41_0008850(murB) |
NRE: | BES08_09735 BES08_11915 |
NOV: | TQ38_013845 TQ38_029265 |
SBIN: | SBA_ch1_34980(murB) |
SPAG: | sphantq_01054(murB) |
SFLA: | SPHFLASMR4Y_00092(murB) |
SKT: | IGS68_06845(murB) IGS68_19455(murB) |
SMUC: | JL100_006720(murB) JL100_020760(murB) |
SROE: | JL101_006570(murB) JL101_019510(murB) |
HPO: | HMPREF4655_20011(murB) |
HPX: | HMPREF0462_1397(murB) |
HPYA: | HPAKL117_06785(murB) |
HPYK: | HPAKL86_06520(murB) |
HPYB: | HPOKI102_07145(murB) |
HPYC: | HPOKI112_07160(murB) |
HPYD: | HPOKI128_06925(murB) |
HPYE: | HPOKI154_07065(murB) |
HPYF: | HPOKI422_07175(murB) |
HPYG: | HPOKI673_07055(murB) |
HPYH: | HPOKI828_07075(murB) |
HPYJ: | HPOKI898_07155(murB) |
HHM: | BN341_16880 BN341_16920 |
HCL: | NCTC13205_00300(murB) |
HSH: | NHP194022_11630(murB) |
HPUL: | NCTC13154_01481(murB) |
CJV: | MTVDSCj20_1641(murB) |
CFV: | CFVI03293_0205(murB) |
CAMP: | CFT03427_0214(murB) |
CCOC: | CCON33237_1661(murB) |
CLR: | UPTC16701_0164(murB) |
CLM: | UPTC16712_0162(murB) |
CAMR: | CAQ16704_0154(murB) |
CHV: | CHELV3228_0089(murB) |
CPIN: | CPIN18020_0169(murB) |
CAMZ: | CVIC12175_1580(murB) |
HCJ: | HCR_11780(murB_1) HCR_12950(murB_2) |
GEM: | GM21_0510 GM21_1080 GM21_2456 |
GEC: | GEO60473_24850(murB) |
GBM: | Gbem_0493(murB-1) Gbem_3180(murB-2) |
GBN: | GEOBRER4_04910(murB_1) GEOBRER4_10280(murB_2) |
GER: | KP004_01675(murB) KP004_04595(murB) |
GSUB: | KP001_10820(murB) KP001_13805(murB) |
GNT: | KP003_01330(murB) KP003_04365(murB) |
GPL: | M1B72_16095(murB) M1B72_19270(murB) |
DVE: | DESUT3_10330(murB) DESUT3_39970(murB1) |
DMA: | DMR_02170(murB) DMR_33250(murB) |
DCB: | C3Y92_00685(murB) C3Y92_05295 |
PSEF: | PSDVSF_15980(murB) PSDVSF_23500(murB1) |
PPOR: | JCM14722_12450(murB) |
BAZ: | BAMTA208_09535(murB) |
BAE: | BATR1942_05410(murB) |
BSON: | S101395_03213(murB) |
BAN: | BA_4048(murB1) BA_5315(murB2) |
BAR: | GBAA_4048(murB1) GBAA_5315(murB2) |
BAH: | BAMEG_0579(murB1) BAMEG_5366(murB2) |
BAI: | BAA_4074(murB1) BAA_5344(murB2) |
BAX: | H9401_3859 H9401_5069 |
BANT: | A16_40540 A16_53290 |
BANR: | A16R_41060 A16R_53920 |
BANS: | BAPAT_3883 BAPAT_5096 |
BANH: | HYU01_19795 HYU01_25980(murB) |
BANV: | DJ46_2748(murB) DJ46_3983(murB) |
BCA: | BCE_3955(murB) BCE_5212(murB) |
BCZ: | BCE33L3668(murB) BCE33L4798(murB) |
BCR: | BCAH187_A3962(murB1) BCAH187_A5229(murB2) |
BCB: | BCB4264_A4010(murB1) BCB4264_A5216(murB2) |
BCU: | BCAH820_3924(murB1) BCAH820_5180(murB2) |
BCG: | BCG9842_B0032(murB2) BCG9842_B1231(murB1) |
BCQ: | BCQ_3695(murB) BCQ_4888(murB) |
BCX: | BCA_4013(murB1) BCA_5217(murB2) |
BAL: | BACI_c38650(murB1) BACI_c50820(murB2) |
BCER: | BCK_09905 BCK_15685(murB) |
BCEF: | BcrFT9_03028 BcrFT9_04054 |
BCY: | Bcer98_2559 Bcer98_3647 |
BTK: | BT9727_3651(murB) BT9727_4778(murB) |
BTL: | BALH_3539(murB) BALH_4604(murB) |
BTB: | BMB171_C3573(murB) BMB171_C4678(murB2) |
BTHR: | YBT1520_20770(murB) YBT1520_26945 |
BTHI: | BTK_20645(murB) BTK_26875 |
BTC: | CT43_CH3910(murB) CT43_CH5132(murB2) |
BTF: | YBT020_19205(murB) YBT020_25215 |
BTM: | MC28_3131(murB1) MC28_4333(murB2) |
BTG: | BTB_c40370(murB1) BTB_c52950(murB2) |
BTI: | BTG_23250 BTG_30220(murB) |
BTN: | BTF1_17845(murB) BTF1_23885 |
BTHT: | H175_ch3972 H175_ch5214 |
BTHU: | YBT1518_21425(murB) YBT1518_28175 |
BTW: | BF38_5079(murB) BF38_828(murB) |
BTHY: | AQ980_04125(murB) AQ980_10375 |
BWE: | BcerKBAB4_3736 BcerKBAB4_4899 |
BWW: | bwei_1045(murB) bwei_4691 |
BMYO: | BG05_2115(murB) BG05_955(murB) |
BTY: | Btoyo_1154 Btoyo_2303 |
BMYC: | DJ92_1000(murB) DJ92_2152(murB) |
BBY: | CY96_18625 CY96_24520(murB) |
BWD: | CT694_21025 CT694_27125 |
BTRO: | FJR70_12955(murB) FJR70_19625 |
BMOB: | MLA2C4_20430 MLA2C4_26390 |
BNT: | GSN03_18480(murB) GSN03_24230 |
BPAC: | LMD38_01460 LMD38_07580(murB) |
BPAN: | NLJ82_18945(murB) NLJ82_24910(murB) |
BALU: | QRY64_22435(murB) QRY64_28255(murB) |
BIF: | N288_09210 N288_13565(murB) |
BFD: | NCTC4823_02569(murB) |
BSHI: | LGQ02_02080(murB) LGQ02_13260(murB) |
BACI: | B1NLA3E_06115(murB) |
BARD: | QRY57_19320(murB) QRY57_24940(murB) |
BCOH: | BC6307_13045 BC6307_21470 |
BKO: | CKF48_01065 CKF48_21455 |
CSOA: | LIS82_10790(murB) LIS82_16500(murB) |
GWC: | GWCH70_0810 GWCH70_1021 |
GMC: | GY4MC1_2776 GY4MC1_2947 |
GTH: | Geoth_2796 Geoth_2972 |
PTL: | AOT13_07765(murB) AOT13_08610 |
PTB: | DER53_08705(murB) DER53_09680(murB) |
PCAL: | BV455_00743(murB_1) BV455_00941(murB_2) |
PARG: | PspKH34_26990(murB) PspKH34_28750(murB2) |
FEC: | QNH15_10665(murB) QNH15_18240(murB) |
RUE: | DT065_04275 DT065_15505 |
SALE: | EPH95_04115(murB) EPH95_15415(murB) |
MSEM: | GMB29_13685(murB) GMB29_17890(murB) |
MLIT: | KDJ21_021705(murB) KDJ21_024685(murB) |
MENL: | MVE64_20265(murB) MVE64_23080(murB) |
MEBZ: | LPC09_06265(murB) LPC09_09170(murB) |
BLEN: | NCTC4824_00222(murB) |
SLMS: | MM221_00885(murB) MM221_11840(murB) |
SAX: | USA300HOU_0764(murB) |
SUQ: | HMPREF0772_12446(murB) |
SUX: | SAEMRSA15_06640(murB) |
SUF: | SARLGA251_06710(murB) |
SAUT: | SAI1T1_2005730(murB) |
SAUJ: | SAI2T2_1005750(murB) |
SAUK: | SAI3T3_1005740(murB) |
SAUQ: | SAI4T8_1005730(murB) |
SAUV: | SAI7S6_1005740(murB) |
SAUW: | SAI5S5_1005700(murB) |
SAUX: | SAI6T6_1005710(murB) |
SAUY: | SAI8T7_1005740(murB) |
SDP: | NCTC12225_02229(murB) |
SPIC: | SAMEA4384060_2133(murB) |
SSH: | NCTC13712_00703(murB) |
SSIM: | SAMEA4384339_0684(murB) |
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