KEGG   ENZYME: 1.4.3.2
Entry
EC 1.4.3.2                  Enzyme                                 
Name
L-amino-acid oxidase;
ophio-amino-acid oxidase (ambiguous)
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor
Sysname
L-amino-acid:oxygen oxidoreductase (deaminating)
Reaction(IUBMB)
an L-amino acid + H2O + O2 = a 2-oxo carboxylate + NH3 + H2O2 [RN:R01259]
Reaction(KEGG)
Substrate
L-amino acid [CPD:C00151];
H2O [CPD:C00001];
O2 [CPD:C00007]
Product
2-oxo carboxylate [CPD:C00161];
NH3 [CPD:C00014];
H2O2 [CPD:C00027]
Comment
A flavoprotein (FAD).
History
EC 1.4.3.2 created 1961
Pathway
ec00250  Alanine, aspartate and glutamate metabolism
ec00270  Cysteine and methionine metabolism
ec00280  Valine, leucine and isoleucine degradation
ec00350  Tyrosine metabolism
ec00360  Phenylalanine metabolism
ec00380  Tryptophan metabolism
ec00400  Phenylalanine, tyrosine and tryptophan biosynthesis
ec00950  Isoquinoline alkaloid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K03334  L-amino-acid oxidase
Genes
HSA259307(IL4I1)
PTR456223(IL4I1)
PPS100980850(IL4I1)
GGO101153847(IL4I1)
PON100936174(IL4I1)
NLE100588082(IL4I1)
HMH116478167(IL4I1)
MCC719114(IL4I1)
MCF102115096(IL4I1)
MTHB126943105
MNI105497172(IL4I1)
CSAB103225935 103235062(IL4I1)
CATY105595313(IL4I1)
PANU101019624(IL4I1) 110742566
TGE112612627(IL4I1)
MLEU105529013(IL4I1)
RRO104667273(IL4I1)
RBB108535617 108535810(IL4I1)
TFN117091607(IL4I1)
PTEH111520078(IL4I1)
CANG105514749(IL4I1)
CJC100393511(IL4I1)
SBQ101036047(IL4I1)
CIMI108292015(IL4I1)
CSYR103258095(IL4I1)
MMUR105865621(IL4I1)
LCAT123623795(IL4I1)
PCOQ105809415(IL4I1) 105812258
OGA100942041(IL4I1)
MMU100328588(Il4i1b) 100470(Lao1) 14204(Il4i1) 73988(4930438A08Rik)
MCAL110293665 110299207(Il4i1) 110304492
MPAH110323726 110324379(Il4i1) 110331259
RNO100360621(Il4i1) 287305(RGD1308564) 298483(Lao1)
MCOC116077959 116095759 116102147(Il4i1)
ANU117703601(Il4i1) 117709387 117711952
MUN110546799(Il4i1) 110547447 110547449 110547463 110552192
CGE100753207 100773063(Il4i1) 118237661
MAUA101827975(Il4i1) 101836430 101840413
PROB127213766(Il4i1) 127219242 127225078
PLEU114684326(Il4i1) 114686459 114704946
MORG121442718 121444808 121447825 121456358 121463608(Il4i1)
MFOT126488192 126492502 126494328 126513079
AAMP119803103(Il4i1) 119804317 119811486 119817212
NGI103728550 103743345 103743685(Il4i1)
HGL101710424(Il4i1)
CPOC100722053(Il4i1) 100735244
CCAN109678621 109683916(Il4i1) 109685329
DORD105985117 105985269 105986039 105994157(Il4i1)
DSP122103786 122103787 122103789 122103841 122125580(Il4i1)
PLOP125355664 125359440 125368104(Il4i1)
NCAR124964052 124967124 124986519
MMMA107141477 107151225(Il4i1) 107159769
OCU100353438 100355677 103347204
OPI101528013(IL4I1) 101530470
TUP102481575 102484685(IL4I1)
GVR103583510 103606222 103607899(IL4I1)
CFA482436 484371(IL4I1)
CLUD112642246 112645120(IL4I1)
VVP112908249 112931512(IL4I1)
VLG121478904(IL4I1) 121481065
NPO129500106(IL4I1) 129520896
AML100465325(IL4I1) 100476680
UMR103657267(IL4I1) 103670918
UAH113243274(IL4I1) 113254224
UAR123776239(IL4I1) 123793625
ELK111142798 111160542
LLV125089747 125098760
MPUF101679701 101682166(IL4I1)
MNP132001676 132006123(IL4I1)
MLK131809419 131818022(IL4I1)
NVS122899845 122913870(IL4I1)
ORO101367095(IL4I1) 101374427
EJU114199615(IL4I1) 114224205
ZCA113914518 113935944(IL4I1)
MLX117998280(IL4I1) 118019531
NSU110572712(IL4I1) 110575253
LWW102726268 102739706
FCA101100683(IL4I1) 111561629
PYU121017594 121018799(IL4I1)
PCOO112850818(IL4I1) 112863418
PBG122479388 122493838(IL4I1)
LRUF124510891 124514368
PTG102958405(IL4I1) 107179172
PPAD109253035(IL4I1) 109254834
PUC125913687 125915931
AJU106970164 106983121
HHV120236036 120240706(IL4I1)
BTA104968452(IL4I1)
BOM102265076(IL4I1) 102281829
BIU109556898 109572132(IL4I1)
BBUB102390358 102390534(IL4I1)
BBIS104995675(IL4I1) 105004981
CHX102183203 102186899(IL4I1)
OAS101103614 105602079(IL4I1)
BTAX128045761 128051007 128062953
ODA120856603 120872106(IL4I1)
CCAD122420530(IL4I1) 122429212
MBEZ129540891 129546518(IL4I1)
SSC100522257(IL4I1) 100524382 100525099
CFR102508990 102515461(IL4I1) 102517966
CBAI105062771(IL4I1) 105064484 105072853
CDK105090941 105094151 105100234(IL4I1)
VPC102525051(IL4I1) 102531830 116279810
BACU103000198(IL4I1) 103011548
LVE103085233 103091507(IL4I1)
OOR101272245 101278148(IL4I1)
DLE111175407 111180588(IL4I1)
PCAD102976825(IL4I1) 102988769
PSIU116744318(IL4I1) 116760484
NASI112399533 112415583(IL4I1)
ECB100055246 100147151 100147304(IL4I1)
EPZ103558296(IL4I1) 103563233 103567078
EAI106840130 106847809 123281322(IL4I1)
MYB102244387 102250318
MYD102756117
MMYO118655360(IL4I1) 118675115
MLF102417897 102425741(IL4I1)
MNA107531789(IL4I1) 107544363
PKL118712191(IL4I1) 118723116
EFUS103294923 103297762(IL4I1)
HAI109391026(IL4I1)
DRO112310093(IL4I1)
SHON118977598(IL4I1)
AJM119050609(IL4I1) 119052159
PDIC114510932(IL4I1)
PHAS123830204(IL4I1) 123832082
MMF118638866(IL4I1)
RFQ117034479(IL4I1)
PPAM129069478 129082948(IL4I1)
PALE102888858 102897392(IL4I1)
PGIG120607388 120615521(IL4I1)
PVP105301784(IL4I1) 105304057
RAY107500425(IL4I1) 107508277
MJV108383350(IL4I1)
TOD119236741 119249626(IL4I1)
SARA101543950(IL4I1)
LAV100657023 100665294(IL4I1) 100677374
TMU101342469 101351869 101357695
ETF101660188 101663616 123522011(IL4I1)
DNM101416894 101417025 101424791 101425232 101425498 101435175 101435655 101445014 101445089 111760677
MDO100010068 100032718 103099142(IL4I1)
GAS123238857 123247310
SHR100917854 100918118 100923259 100932442 116422917(IL4I1)
AFZ127555560 127555562 127556598 127560775
PCW110194214 110205983 110219789(IL4I1)
OAA100079395(IL4I1)
GGA417039(IL4I1)
PCOC116236713(IL4I1)
MGP100540143(IL4I1)
CJO107321571(IL4I1)
TPAI128075039(IL4I1)
LMUT125686219(IL4I1)
NMEL110406676(IL4I1)
APLA101790142(IL4I1)
ACYG106049930(IL4I1)
CATA118260272(IL4I1)
AFUL116500228(IL4I1)
TGU100222394(IL4I1)
SCAN103824938(IL4I1)
PMOA120503973(IL4I1)
OTC121338701(IL4I1)
PRUF121359413(IL4I1)
GFR102037637(IL4I1)
FAB101808392(IL4I1)
OMA130263312(IL4I1)
PHI102109935(IL4I1)
PMAJ107198862(IL4I1)
CCAE111936793(IL4I1)
CCW120412144(IL4I1)
CBRC103614653(IL4I1)
ZAB106630234(IL4I1)
ACHL103802632(IL4I1)
SVG106864064(IL4I1)
MMEA130586394(IL4I1)
HRT120764724(IL4I1)
FPG106112282(IL4I1)
FCH102046121(IL4I1)
CLV102086260(IL4I1)
EGZ104133949(IL4I1)
NNI104011855(IL4I1)
PCRI104029078(IL4I1)
PLET104614359(IL4I1)
EHS104510026(IL4I1)
PCAO104047030
TALA104364431(IL4I1)
PADL103922928(IL4I1)
AFOR103898527(IL4I1)
ACHC115337903(IL4I1)
HALD104321814(IL4I1)
HLE104832888(IL4I1)
AGEN126034931
GCL127029193
CCRI104167352(IL4I1)
CSTI104564115(IL4I1)
CMAC104474575(IL4I1)
MUI104544387(IL4I1)
BREG104643952(IL4I1)
FGA104081786(IL4I1)
GSTE104252210(IL4I1)
LDI104351316(IL4I1)
MNB103772568(IL4I1)
OHA104328438(IL4I1)
NNT104410174(IL4I1)
SHAB115618843(IL4I1)
DPUB104297498(IL4I1)
PGUU104463619(IL4I1) 104464838
ACAR104517848(IL4I1)
CPEA104392281(IL4I1)
CVF104287011(IL4I1)
RTD128901647(IL4I1)
CUCA104059733(IL4I1)
TEO104380267(IL4I1)
BRHI104496365(IL4I1)
AAM106482065(IL4I1)
AROW112978516(IL4I1)
TGT104577558(IL4I1)
DNE112992962(IL4I1)
SCAM104139184(IL4I1)
ASN102368180 102384151 102384392
AMJ102565465 102573609(IL4I1)
PSS102454164 102456958 102457207 102457453 102458451 102461938
CMY102942718 102945232 102945460 102945689 102945918 102947871
CCAY125621481 125621772 125621792 125621793 125629566
DCC119842483 119842484 119843047 119843050
CPIC101935439 101941085 101942263 101942815 101943090 101944444
TST117887160 117887178 117887179 117887181 117887215
CABI116819430 116820392 116820393 116820394
MRV120383048 120383050 120383102 120383683 120392389 120394231
ACS100563852 100566795 100566990 100567189
ASAO132765102 132765119 132765120 132765121 132766725
PVT110071372 110088018 110088019 110088021 110088022
SUND121918314 121920299 121920300 121920301 121920302 121920303
PBI103050915 103053826 103058185
PMUR107289616 107289625 107289632 107292853
CTIG120315924 120315945 120315946 120315948
TSR106539221 106544367 106555017
PGUT117668040 117668047
APRI131190293 131190406 131190410 131191202
PTEX113449660 113453618
NSS113422237 113424979 113428977 113430285
VKO123034405 123034410 123034411 123034607
PMUA114588443 114588610 114588621 114590937
PRAF128408725 128408894 128408900 128408905
ZVI118080102 118080932 118080933
HCG128343970 128343971 128343972 128343973 128344479
GJA107124516 107124520
STOW125427720(IL4I1)
EMC129327468 129327681 129327696 129327697 129327698 129328350 129328515 129328976 129329228
XLA108696562 108696644(il4i1.L)
XTR100493881(il4i1) 100496394
NPR108791768 108791770 108791771
RTEM120915363 120915364 120915365 120915366
BBUF120997974 120997986
BGAR122928754 122928755
MUO115465000(IL4I1)
DRE337166(si:dkey-40g16.6)
SRX107709125 107717264
SANH107657246 107670951
SGH107586302 107601700
CCAR109058498 109064604 109103696
CAUA113058421 113115537
CGIB127972193 128029454
PTET122358961(il4i1)
LROH127176849(il4i1)
OMC131520712(il4i1)
PPRM120478840(il4i1)
RKG130096810(il4i1)
MAMB125249670(il4i1)
CIDE127496103
MASI127421781 127429679
TROS130564943(il4i1)
TDW130428904(il4i1)
MANU129437970(il4i1)
IPU108277784
IFU128621812(il4i1)
PHYP113532631(il4i1)
SMEO124394502(il4i1)
TFD113660452(il4i1)
TVC132857847(il4i1)
AMEX103030662 103030984 103034230
CMAO118827307 118827317
EEE113579601(il4i1)
CHAR105893732(il4i1) 105899129
TRU101072153 101072660(il4i1)
TFS130523058 130535153(il4i1)
TNGGSTEN00004026G001 GSTEN00026846G001
LCO104937478 104937491 104940603(il4i1)
NCC104942625
TBEN117468930(il4i1) 117469869 117486838
CGOB115017826(il4i1) 115024066
PGEO117457196 117457681 117457780 117463406 117463579 117463583
GACU117538261 117550024 117562130(il4i1) 117562636
ELY117246507 117246508 117252548 117260093(il4i1)
EFO125883491 125883492 125888255(il4i1) 125890786
PLEP121943552(il4i1) 121944726 121962097 121962098 121962508 121962509
SLUC116038885(il4i1) 116052105 116052106 116052108 116052109 116052146
ECRA117942447(il4i1) 117962121 117962122
ESP116680441 116695345 116695346 116695347
PFLV114545909 114545953 114546186 114546189 114546190 114546191 114552578(il4i1)
GAT120814801(il4i1) 120823029
PPUG119209117(il4i1) 119222932
AFB129093284 129093496 129094755(il4i1)
CLUM117741837(il4i1)
MSAM119882627(il4i1) 119896366 119912615 119912745 119918947 119918948
SCHU122870147 122870148 122879528(il4i1)
CUD121504363 121504400 121504402 121504874 121505065 121505066 121527143(il4i1)
ALAT119011603(il4i1) 119026630 119026646
MZE101470741 101473683 101473989 112431521 112431528
ONL100695605 100697201 100703044 100703315 100707943
OAU116311629 116311630 116312996(il4i1) 116313896 116331917 116333564
OLA101160780 101161073 101163441 101171229 105356325
OML112149798(il4i1) 112155644 112155698 112156072 112156354 112156355
XMA102218509 102227815 102228075 106700049
XCO114149637 114156799 114156839 114157965
XHE116708192 116732114 116732163 116732189
PRET103461196 103474367 103480925 103480937 103480938
PFOR103149034 103149035 103149095 103149096 103156786 103156791
PLAI106935008 106947289 106947294 106947295
PMEI106908903 106911400 106926808 106926809 106926813 106926815
GAF122820715 122820716 122820989 122820990 122833314(il4i1)
CVG107082273 107099630 107099631 107099633 107099634 107099636 107103271
CTUL119777187 119777189 119777195 119791854(il4i1)
GMU124880954 124881157 124881159 124881160 124881161 124881168 124883694(il4i1)
NFU107374444 107374445 107380798(il4i1)
KMR108247696(il4i1) 108248303 108248304
ALIM106522793 106525020 106525021 106535079
NWH119429218(il4i1)
AOCE111571215 111571474 111585375 111585379
MCEP125009163 125013589(il4i1) 125024027 125024064
CSEM103377764(il4i1)
POV109639351 109644254
SSEN122766864 122773264(il4i1)
HHIP117752108 117752109 117752194 117772864(il4i1)
HSP118102865 118102964 118102969 118106035(il4i1)
LCF108900578(il4i1) 108902378 108902379
SDU111234776(il4i1) 111236665 111236666
SLAL111652095 111652096 111671319(il4i1)
XGL120792272(il4i1) 120797257
HCQ109510681
SSCV125972298
SBIA133504486(il4i1)
PEE133405243(il4i1)
PTAO133482133(il4i1)
BPEC110161951(il4i1)
MALB109954170(il4i1)
BSPL114851219 114851323 114868580(il4i1)
SJO128360557(il4i1) 128383623 128384080 128384086
SASA106561133 106580948 106612549
STRU115163246 115197037 115206184
OTW112265402 112266925
OMY110492681 110503766(il4i1) 110507168
OGO123993959 124004792
ONE115134799 115141709
OKI109909049 116353633
OKE118373662 118397336
SALP111949891 111959920 111962163
SNH120018275 120029032(il4i1) 120066129
CCLU121532047 121565117 121567622
ELS105024042(il4i1)
SFM108928687(il4i1)
PKI111833916(il4i1)
AANG118209514(il4i1)
LOC102691176 102696231 102698727
PSPA121303996(il4i1) 121324337
ARUT117397171 117397368 117422133 117422222
PSEX120535817(il4i1) 120536710
LCM102345877 102355982 102367420
EAF111712914
LSM121116906 121116907
TCF131876857 131891894
BGT106053389
HRF124110692 124110693 124110715 124110716 124110823 124110824 124113997 124113999 124114004 124116185 124132876 124149366 124151981 124152001
HRJ124262556 124276867 124281648 124288113 124288116 124291771 124291796
CRG105329637 105336823
CVN111106941 111108980 111110105
CANU128178369
OED125650797 125651195 125652609
PMAX117321607 117340737
MMER123527946 123528636 123528870 123528990 123529239 123530170 123530240 123536688 123540459 123543766 123551352 123551752 123551772 123553585 123553597 123553611
RPHI132732968 132739731
DPOL127841634 127869074 127870092
XEN124439720 124445263 124454201 124454202 124454222 124454577 124454760 124455753 124456649
FVNFVRRES_04066
PTRCPtA15_18A388
PSTRPst134EA_027084
 » show all
Reference
1
  Authors
Meister, A. and Wellner, D.
  Title
Flavoprotein amino acid oxidase.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 609-648.
Reference
2  [PMID:13843884]
  Authors
WELLNER D, MEISTER A.
  Title
Crystalline L-amino acid oxidase of Crotalus adamanteus.
  Journal
J Biol Chem 235:2013-8 (1960)
Other DBs
ExplorEnz - The Enzyme Database: 1.4.3.2
IUBMB Enzyme Nomenclature: 1.4.3.2
ExPASy - ENZYME nomenclature database: 1.4.3.2
BRENDA, the Enzyme Database: 1.4.3.2
CAS: 9000-89-9
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