KEGG   ENZYME: 1.8.99.2
Entry
EC 1.8.99.2                 Enzyme                                 
Name
adenylyl-sulfate reductase;
adenosine phosphosulfate reductase;
adenosine 5'-phosphosulfate reductase;
APS-reductase;
APS reductase;
AMP, sulfite:(acceptor) oxidoreductase (adenosine-5'-phosphosulfate-forming)
Class
Oxidoreductases;
Acting on a sulfur group of donors;
With unknown physiological acceptors
Sysname
AMP,sulfite:acceptor oxidoreductase (adenosine-5'-phosphosulfate-forming)
Reaction(IUBMB)
AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor [RN:R00860]
Reaction(KEGG)
R00860 > R08553;
(other) R04927
Substrate
AMP [CPD:C00020];
sulfite [CPD:C00094];
acceptor [CPD:C00028]
Product
adenylyl sulfate [CPD:C00224];
reduced acceptor [CPD:C00030]
Comment
An iron flavoprotein (FAD). Methyl viologen can act as acceptor.
History
EC 1.8.99.2 created 1972
Pathway
ec00920  Sulfur metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K00394  adenylylsulfate reductase, subunit A
K00395  adenylylsulfate reductase, subunit B
Genes
TIGTHII_3105 THII_3106
THISHZT40_21240(aprB) HZT40_21245
TUNJ9260_16720(aprB) J9260_16725
TLOJ9253_18120(aprB) J9253_18125
TSBHMY34_11175(aprB) HMY34_11180
TANIJ8380_05600 J8380_12965(aprB) J8380_12970
ALVAlvin_1120 Alvin_1121
ATEPAtep_15380 Atep_15390
TVIThivi_3299 Thivi_3300
TMBThimo_1219 Thimo_1220
TSYTHSYN_16395 THSYN_16400
TTPE6P07_06890 E6P07_06895(aprB)
THIPN838_08140 N838_08145(aprB) N838_10735(aprB) N838_10740
CJAPGWK36_04765(aprB) GWK36_04770
THIMKFB96_04245(aprB) KFB96_04250
TBOGLT988_00210(aprA) LT988_00215(aprB)
TGRTgr7_0350 Tgr7_0351
TKMTK90_0064 TK90_0065
TNITVNIR_3611 TVNIR_3612
TTITHITH_01410 THITH_01415
TTCFOKN1_1662 FOKN1_1663
SLIMSCL_0600 SCL_0601 SCL_2473 SCL_2474
SVASVA_2607 SVA_2608 SVA_3564 SVA_3565
ACIIC4901_07620(aprA) C4901_07625(aprB) C4901_14675(aprB) C4901_14680(aprA)
ATYA9R16_009310(aprA) A9R16_009315(aprB) A9R16_013560(aprB) A9R16_013565(aprA)
TBNTBH_C0421 TBH_C0422
SEDSAAY24_12255 AAY24_12260
TSNW908_01270 W908_01275
THINCRN91_00270(aprB) CRN91_00275(aprA)
THOSP60_04585 SP60_04590
REVHUE57_00495 HUE57_00500(aprB)
RMARmag_0087 Rmag_0088
REOHUE58_06190(aprB) HUE58_06195
VOKCOSY_0091(aprB) COSY_0092(aprA)
EPSL0Y14_00895(aprB) L0Y14_00900(aprA)
EBHBSEPE_0126(aprB) BSEPE_0127(aprA)
BTHGMS2017_2046 MS2017_2047
ENMEBS_2148(aprA) EBS_2149(aprB)
IFOCVFO_0391(aprB) CVFO_0392(aprA)
APHFCVPH_1379(aprA) CVPH_1380(aprB)
SHDSUTH_02771(aprA) SUTH_02772(aprB)
TBDTbd_0872 Tbd_0873 Tbd_2282 Tbd_2283
SLTSlit_1714 Slit_1715
SEMEMIZ01_1494 MIZ01_1495
SDRSCD_n01726(aprB) SCD_n01727(aprA)
SPLBSFPGR_21700 SFPGR_21710(aprB) SFPGR_28000(aspB) SFPGR_28010(apsA)
SLACSKTS_25230(aspB) SKTS_25240(apsA) SKTS_27380 SKTS_27390
DDZDSYM_23230 DSYM_23240
DVUDVU_0846(aprB) DVU_0847(aprA)
DVLDvul_2136 Dvul_2137
DVMDvMF_1709 DvMF_1710 DvMF_2892 DvMF_2893
DVGDeval_0776 Deval_0777
DDSDdes_2129 Ddes_2130
DFIAXF13_12610 AXF13_12615
DPGDESPIGER_1662 DESPIGER_1663 DESPIGER_2209 DESPIGER_2210
DEFCNY67_01435(aprB) CNY67_01440(aprA)
DTRRSDT_0365(aprA) RSDT_0366(aprB)
DFLDFE_2055 DFE_2056
DSDGD606_15920(aprB) GD606_15925
DMADMR_05390(aprB) DMR_05400(aprA) DMR_29670 DMR_29680
DCBC3Y92_17705(aprA) C3Y92_17710(aprB)
DGGDGI_0457(aprA) DGI_0458(aprB)
DDEDde_1109 Dde_1110
DMSE8L03_09650 E8L03_09655(aprB)
DSADesal_0229 Desal_0230
DHYDESAM_20543(aprA) DESAM_20544
DAFDesaf_0100 Desaf_0101 Desaf_0338 Desaf_0339
DASDaes_3033 Daes_3034
DPIBN4_11809(aprA) BN4_11810(aprB)
DEJAWY79_04195 AWY79_04200
PPRFDPRO_2420(aprB) DPRO_2421(aprA)
PSELGM415_07085(aprB) GM415_07090
DDNDND132_2643 DND132_2644
DSXGD604_03185(aprB) GD604_03190
PBIZLWC08_14795(aprA) LWC08_14800(aprB)
DBADbac_3197 Dbac_3198
DOAAXF15_05945 AXF15_05950
DRTDret_1966(aprA) Dret_1967(aprB)
DPSDP1104 DP1105
DSFUWK_02023 UWK_02024
DAKDaAHT2_1471 DaAHT2_1472
DPRDespr_0771 Despr_0772
DEOCAY53_05535 CAY53_05540 CAY53_10880 CAY53_10885
DOGHP555_07435(aprB) HP555_07440
DBKDGMP_04490(aprB) DGMP_04500(aprA)
DOLDole_0997 Dole_0998
DMLDmul_31450(aprA) Dmul_31460(aprB)
DALDalk_1569 Dalk_1570
DATHRM2_04510(aprA) HRM2_04520(aprB)
DTOTOL2_C04460(aprA) TOL2_C04470(aprB)
DOVDSCO28_47930(aprA) DSCO28_47940(aprB)
DWDDSCW_40190(aprB) DSCW_40200(aprA) DSCW_42360 DSCW_42370(aspB)
DALKDSCA_38700(aprA) DSCA_38710(aprB_1) DSCA_40820 DSCA_40830 DSCA_58900(aprB_2)
DLIdnl_16910(aprB) dnl_16920(aprA)
DMMdnm_076460(aprB) dnm_076470(aprA)
DEKDSLASN_36220(aspB_2) DSLASN_36230(aprA)
DAODesac_0736 Desac_0737
DTIDesti_1442 Desti_1443
SFUSfum_1047 Sfum_1048
DAXFDQ92_09410(aprB) FDQ92_09415(aprA)
DBRDeba_0981 Deba_0982
DHRLGS26_04230(aprB) LGS26_04235(aprA)
FILBN1229_v1_3249 BN1229_v1_3251
FIYBN1229_v1_2672 BN1229_v1_2673
MAGQMGMAQ_3494 MGMAQ_3495
PUBSAR11_0836(aprB) SAR11_0837(aprA)
PEGE5R92_01800 E5R92_01805(aprB)
APMHIMB5_00004970 HIMB5_00004980
CACCA_C0104 CA_C0105
CAESMB_G0105(frdA) SMB_G0106
CAYCEA_G0105 CEA_G0106
CBECbei_4188 Cbei_4189
CBZCbs_4188 Cbs_4189
CBEILF65_04697 LF65_04698
CKLCKL_1797 CKL_1798(aprA)
CKRCKR_1669 CKR_1670
CCBClocel_0525 Clocel_0526
CLSCXIVA_15130 CXIVA_15140
CSRCspa_c29740 Cspa_c29750
CPASClopa_4346 Clopa_4347
CPATCLPA_c35250 CLPA_c35260
CPAECPAST_c35250 CPAST_c35260
CSBCLSA_c38940 CLSA_c38950
CLTCM240_2791 CM240_2792
CACECACET_c13370 CACET_c13380
CCKCcar_10430 Ccar_10435
CBUTATN24_08820 ATN24_08825
CTYKCTK_C12860 CTK_C12870
CEUA7L45_10245 A7L45_10250
CFMBJL90_12010 BJL90_12015
CDYF3K33_21430 F3K33_21435
CMAHC1I91_02180 C1I91_02185
CRWCROST_003020(aprA) CROST_003030
AMTAmet_3494 Amet_3495
GFEGferi_06095 Gferi_06100
HSCHVS_02765(nadB1) HVS_02770
RUMCK1_29010 CK1_29020
RUJE5Z56_09520 E5Z56_09525
CLEClole_0049 Clole_0050
CEWEKH84_03165 EKH84_03170
COOCCU_23240 CCU_23250
CEVLK421_04960 LK421_04965
ROBCK5_24520
BLABEYS05_06475 EYS05_06480
BLIQINP51_13750 INP51_13755
CPYCphy_1830 Cphy_1831
BPRLCL2_12010 CL2_12020
EHLEHLA_0507 EHLA_0508
ANRAna3638_18045
ACELacsn021_29500 acsn021_29510
EELEUBELI_01895 EUBELI_01896
WCPH9Q76_03810 H9Q76_03815
EREEUBREC_2471 EUBREC_2472
ERTEUR_26600 EUR_26610
ERAERE_07490 ERE_07500
TEBT8CH_2747 T8CH_2748(aprA)
DORDesor_1735 Desor_1736
DAIDesaci_2312 Desaci_2319 Desaci_2320
DMIDesmer_0631 Desmer_0632 Desmer_1686 Desmer_1687
DCADesca_2377 Desca_2378
PTHPTH_0239(SdhA) PTH_0240
DRMDred_0636 Dred_0637
DRUDesru_0816 Desru_0817 Desru_3376 Desru_3377
DFGB0537_03650 B0537_03655
DAEDtox_3577 Dtox_3578
DKUDesku_1073 Desku_1074 Desku_1950 Desku_1951
DAUDaud_0788 Daud_0789 Daud_1885 Daud_1886 Daud_1888 Daud_1889
AACXDEACI_0464 DEACI_0465 DEACI_4177 DEACI_4178
TJRTherJR_2248 TherJR_2249
DGIDesgi_1510 Desgi_1511 Desgi_3701 Desgi_3702
CTHMCFE_1042 CFE_1043
ABUTAmi103574_14725 Ami103574_14730
ADGAdeg_0924 Adeg_0925 Adeg_1080 Adeg_1081
CSCCsac_1640 Csac_1641
ATEAthe_1191 Athe_1192
CHDCalhy_1541 Calhy_1542
CKICalkr_1174 Calkr_1175
CKNCalkro_1506 Calkro_1507
CCHAELD05_08150 ELD05_08155
CDIACaldiYA01_13150 CaldiYA01_13160
TNRThena_1598 Thena_1599
TACITDSAC_1570 TDSAC_1571
HORHore_02120 Hore_02130
HALSD7D81_17745 D7D81_17750
IFNGM661_14395 GM661_14400
AARAcear_1952 Acear_1970 Acear_1971
HHLHalha_2337 Halha_2338
CADCuri_c25240 Curi_c25250(aprA)
VRM44547418_00331(frdA) 44547418_00332
MEDMELS_1712 MELS_1713
MMAXLCQ47_01130 LCQ47_01135
SRISELR_27430(fdx) SELR_27440
PUFUFO1_1134 UFO1_1135
PFTJBW_03276 JBW_03277
MANAMAMMFC1_02591(nadB_1) MAMMFC1_02592
EBMSG0102_26840 SG0102_26850
ATBJ4859_12670 J4859_12675
KSTKSMBR1_3875(aprB) KSMBR1_3876(apsA)
BROCIPI25_12130 IPI25_12135
BPITBPIT_06990 BPIT_07000
JETL3J17_12740 L3J17_12745
IPOIlyop_2845 Ilyop_2846
LBALebu_0374 Lebu_0375
LOTAXF11_03240 AXF11_03245
LEQBCB68_05990 BCB68_05995
LHFJCM16775_2043 JCM16775_2044
LSZJCM16776_1593 JCM16776_1594
LWDJCM16777_1749 JCM16777_1750
FSUFisuc_0144 Fisuc_0145
FSCFSU_0547 FSU_0548
CTECT0864(aspB) CT0865(apsA)
CLZBIU88_06785 BIU88_06790
CCHCag_1585 Cag_1586
CPBCphamn1_1837 Cphamn1_1838
PPHPpha_0039 Ppha_0040
TYETHEYE_A1832(aprA) THEYE_A1833(aprB)
DTPJZK55_21800(aprA) JZK55_21810(aprB)
LFCLFE_1826 LFE_1827
LFILFML04_0489 LFML04_0490
LFPY981_02510 Y981_02515
LEGABH19_02945 ABH19_02950
TIDThein_0285 Thein_0286
TOPTOPB45_0176 TOPB45_0177
TCMHL41_08915 HL41_08920
THETF1847_07175 F1847_07180(aprB)
CTHITHC_1311 THC_1312
TAVG4V39_03260 G4V39_03265(aprB)
TMAIFVE67_03060 FVE67_03065(aprB)
AFUAF_1669 AF_1670
AFGAFULGI_00019180 AFULGI_00019190
APOArcpr_1261 Arcpr_1262
AVEArcve_0422 Arcve_0423
ASTAsulf_02111 Asulf_02112
FPLFerp_2217 Ferp_2218
GACGACE_1095 GACE_1096
GAHGAH_02065 GAH_02066
PAIPAE2561 PAE2562 PAE2563 PAE2564
PCLPcal_1428 Pcal_1429
PASPars_1234 Pars_1235
PYRP186_1798 P186_1799
POGPogu_1003 Pogu_1004
CMACmaq_0272 Cmaq_0273
TTNTTX_0438(apsA) TTX_0439
TUZTUZN_0714 TUZN_0715
VDIVdis_2089 Vdis_2090
VMOVMUT_0493 VMUT_0494
 » show all
Reference
1  [PMID:5421934]
  Authors
Michaels GB, Davidson JT, Peck HD Jr.
  Title
A flavin-sulfite adduct as an intermediate in the reaction catalyzed by adenylyl sulfate reductase from Desulfovibrio vulgaris.
  Journal
Biochem Biophys Res Commun 39:321-8 (1970)
DOI:10.1016/0006-291X(70)90579-6
Other DBs
ExplorEnz - The Enzyme Database: 1.8.99.2
IUBMB Enzyme Nomenclature: 1.8.99.2
ExPASy - ENZYME nomenclature database: 1.8.99.2
BRENDA, the Enzyme Database: 1.8.99.2
CAS: 9027-75-2
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