| Entry |
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| Name |
6-O-methylnorlaudanosoline 5'-O-methyltransferase
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| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
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| Sysname |
S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase
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| Reaction(IUBMB) |
S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline [RN: R04714]
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| Reaction(KEGG) |
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| Substrate |
S-adenosyl-L-methionine [CPD: C00019];
6-O-methylnorlaudanosoline [CPD: C05203]
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| Product |
S-adenosyl-L-homocysteine [CPD: C00021];
nororientaline [CPD: C05317]
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| Comment |
Nororientaline is a precursor of the alkaloid papaverine.
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| History |
EC 2.1.1.121 created 1999
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| Pathway |
| ec00950 | Isoquinoline alkaloid biosynthesis |
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| Reference |
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| Authors |
Rueffer M, Nagakura N, Zenk MH |
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| Title |
A Highly Specific O-Methyltransferase for Nororientaline Synthesis Isolated from Argemone platyceras Cell Cultures. |
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| Journal |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.1.1.121 |
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| LinkDB |
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