| Entry |
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| Name |
tRNA1Val (adenine37-N6)-methyltransferase;
YfiC
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| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
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| Sysname |
S-adenosyl-L-methionine:tRNA1Val (adenine37-N6)-methyltransferase
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| Reaction(IUBMB) |
S-adenosyl-L-methionine + adenine37 in tRNA1Val = S-adenosyl-L-homocysteine + N6-methyladenine37 in tRNA1Val
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| Substrate |
S-adenosyl-L-methionine [CPD: C00019];
adenine37 in tRNA1Val
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| Product |
S-adenosyl-L-homocysteine [CPD: C00021];
N6-methyladenine37 in tRNA1Val
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| Comment |
The enzyme specifically methylates adenine37 in tRNA1Val (anticodon cmo5UAC).
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| History |
EC 2.1.1.223 created 2011
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| Orthology |
| K15460 | tRNA1Val (adenine37-N6)-methyltransferase |
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| Genes |
| ECOO: | ECRM13514_3402(yfiC) |
| ECOH: | ECRM13516_3258(yfiC) |
| EDJ: | ECDH1ME8569_2502(yfiC) |
| ECOI: | ECOPMV1_02757(yfiC) |
| REE: | electrica_01188(yfiC) |
| RTG: | NCTC13098_01698(yfiC) |
| CLAP: | NCTC11466_00900(yfiC) |
| KIE: | NCTC12125_00142(yfiC) |
| AHN: | NCTC12129_03813(yfiC) |
| METY: | MRY16398_12540(yfiC) |
| PSHI: | SAMEA2665130_2616(yfiC) |
| SMW: | SMWW4_v1c37790(yfiC) |
| SFJ: | SAMEA4384070_3790(yfiC) |
| SOF: | NCTC11214_02984(yfiC) |
| LBQ: | CKQ53_00160 CKQ53_17985 |
| TPTY: | NCTC11468_02849(yfiC) |
| PHEI: | NCTC12003_01400(yfiC) |
| PRJ: | NCTC6933_02561(yfiC) |
| LRI: | NCTC12151_02432(yfiC) |
| HIC: | NTHIC486_00565(yfiC) |
| HPIT: | NCTC13334_00917(yfiC) |
| HHZ: | NCTC10839_00185(yfiC) |
| HAEG: | NCTC8502_00717(yfiC) |
| PDAG: | 4362423_01992(yfiC) |
| ADP: | NCTC12871_00701(yfiC) |
| ALIG: | NCTC10568_02281(yfiC) |
| ASEG: | NCTC10977_00499(yfiC) |
| AVT: | NCTC3438_00310(yfiC) |
| RPNE: | NCTC8284_03551(yfiC) |
| PAET: | NCTC13378_02113(yfiC) |
| VPL: | SA104470976_02064(yfiC) |
| SALH: | HMF8227_00504(yfiC) |
| AEL: | NCTC12917_00565(yfiC) |
| CDIZ: | CEDIAZO_01369(yfiC) |
| BTHO: | Btheta7330_02462(yfiC) |
| BCEL: | BcellWH2_05416(yfiC) |
| PCRE: | NCTC12858_00045(yfiC) |
| PCAG: | NCTC12856_01040(yfiC) |
| POC: | NCTC13071_01868(yfiC) |
| PBY: | L6471_07360 L6471_09520 |
| SBAO: | L6469_01760 L6469_04445 |
| SMIZ: | 4412673_00530(yfiC) |
| STHA: | NCTC11429_00819(yfiC) |
| PSEZ: | HME7025_00931(yfiC) |
| PHG: | KCTC32516_01258(yfiC) |
| AALG: | AREALGSMS7_01910(yfiC) |
| AANR: | KCTC52924_00883(yfiC_2) |
| KOS: | KORDIASMS9_01859(yfiC) |
| KAN: | IMCC3317_36330(yfiC) |
| SPON: | HME9304_01979(yfiC) |
| FBU: | UJ101_01721(yfiC|trmX) |
| CGLE: | NCTC11432_02846(yfiC) |
| CTAI: | NCTC12078_02787(yfiC) |
| CTAK: | 4412677_01307(yfiC) |
| CJG: | NCTC13459_01488(yfiC) |
| CANT: | NCTC13489_02671(yfiC) |
| PTAN: | CRYO30217_00936(yfiC) |
| MNU: | NCTC10166_00128(yfiC) |
| MOE: | NCTC10151_00425(yfiC) |
| MGLY: | NCTC10194_00166(yfiC) |
| MCOU: | NCTC10179_00259(yfiC) |
| MPU: | MYPU_4720(MYPU_4720) |
| MEDW: | NCTC10132_00377(yfiC) NCTC10132_00378 |
| MGAL: | NCTC10186_00801(yfiC) |
| MCIT: | NCTC10181_00767(yfiC) |
| MMAU: | NCTC10168_00407(yfiC) |
| MCOB: | NCTC10184_00207(yfiC) |
| MALA: | NCTC10135_00190(yfiC) |
| MSAI: | NCTC10113_01141(yfiC_2) |
| MOB: | NCTC10112_00529(yfiC) |
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| Reference |
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| Authors |
Golovina AY, Sergiev PV, Golovin AV, Serebryakova MV, Demina I, Govorun VM, Dontsova OA |
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| Title |
The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA1Val(cmo5UAC). |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.1.1.223 |
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| LinkDB |
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