KEGG   ENZYME: 2.1.1.278
Entry
EC 2.1.1.278                Enzyme                                 
Name
indole-3-acetate O-methyltransferase;
IAA carboxylmethyltransferase;
IAMT
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:(indol-3-yl)acetate O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + (indol-3-yl)acetate = S-adenosyl-L-homocysteine + methyl (indol-3-yl)acetate [RN:R10452]
Reaction(KEGG)
R10452
Substrate
S-adenosyl-L-methionine [CPD:C00019];
(indol-3-yl)acetate [CPD:C00954]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
methyl (indol-3-yl)acetate [CPD:C20635]
Comment
Binds Mg2+. The enzyme is found in plants and is important for regulation of the plant hormone (indol-3-yl)acetate. The product, methyl (indol-3-yl)acetate is inactive as hormone [2].
History
EC 2.1.1.278 created 2013
Orthology
K18848  indole-3-acetate O-methyltransferase
Genes
PCAN112574924 112576213
MYI110453983 110459980
LAK106152812 106152823 106180116
SPIS111319230
ATHAT5G55250(IAMT1)
ALY9300463
CRB17876787
CSAT104726072 104731592 104761558 109127202
EUSEUTSA_v10015669mg
BRP103844968
BNA106429974
BOE106314016
RSZ108827575
THJ104811634 104817688
CPAP110820813
CIT102609472
CICCICLE_v10008599mg
PVY116145152
MINC123192072 123201772 123202376
TCC18593419
GRA105781276
GHI107916882 107921728
GAB108481923
DZI111276433 111302246
EGR104448179
GMX100801476 100805902 100807953
GSJ114384238 114395612 114402697 114424307
PVUPHAVU_006G048600g PHAVU_008G272800g
VRA106764291 106774727
VAR108337490 108342409
VUN114187551 114193541
CCAJ109806364 109811319
APRC113854354 113874579
MTRMTR_3g052700 MTR_3g054330 MTR_5g093900
CAM101501068
LJALj2g3v3222870.1(Lj2g3v3222870.1) Lj6g3v0819010.1(Lj6g3v0819010.1)
ADU107473281 107496314
AIP107606437 107616468
AHF112701906 112720225 112767332 112790358
LANG109329113 109350940 109359499
FVE101295605
RCN112167364
PPER18779912 18780210 18780650 18787700
PMUM103326506 103326551 103326552 103333170
PAVI110752403 110752586 110766633 110766652 110766659 110768917
PDUL117619897 117624998 117625448 117626244
MDM103428134 103448357
PXB103927001 103951421
ZJU107403613 107434320
MNT21395657
CSV101213472
CMO103490122
BHJ120085398
MCHA111010498 111010558
CMAX111476788 111480601
CMOS111442937 111445917
CPEP111788985 111797338
RCU8268129
JCU105633024
HBR110646361 110670024
MESC110601438 110610534
POP7487519
PEU105141854
PALZ118056815
JRE108983414 108992349
QSU112029893
QLO115955000
TWL119985165 119989971
VVI100258858
VRI117910005
SLY101263921 101268451
SPEN107005882 107024610
SOT102590393 102598710
SSTN125862547 125875655
CANN107877415
NTA107814352 107819865 107821105 107832655
NSY104225348 104233292
NTO104088383 104121023
NAU109208188 109226709
INI109187364 109190737
ITR116011409 116022530
SIND105174912
OEU111376492 111395122
EGT105969193
SSPL121756544 121756867 121786407
HAN110890061
ECAD122593380
LSV111898207
CCAV112508026
DCR108216756
CSIN114280095 114321588
BVG104891752 104891754
SOE110777861
CQI110720881 110723927
NNU104594143 104606532
MING122060482 122094202
TSS122640523 122641758
PSOM113285782 113333215
NCOL116259088
OSA107276275 4337315 4340899
DOSAOs04t0665200-01(Os04g0665200) Os06t0322400-00(Os06g0322400) Os06t0323100-01(Os06g0323100)
OBR102702090 102704052
SVS117850524
PVIR120642779
PHAI112901107 112901210
PDA103702327
EGU105050524
MUS103995398 103995407
ATR18429711
MBRMONBRDRAFT_27501
SREPTSG_08577 PTSG_11672
MMAIsS8_3498
STARG3545_19560
PHRC6569_06540
 » show all
Reference
1  [PMID:12897246]
  Authors
Zubieta C, Ross JR, Koscheski P, Yang Y, Pichersky E, Noel JP
  Title
Structural basis for substrate recognition in the salicylic acid carboxyl methyltransferase family.
  Journal
Plant Cell 15:1704-16 (2003)
DOI:10.1105/tpc.014548
  Sequence
[ath:AT5G55250]
Reference
2  [PMID:17926040]
  Authors
Li L, Hou X, Tsuge T, Ding M, Aoyama T, Oka A, Gu H, Zhao Y, Qu LJ
  Title
The possible action mechanisms of indole-3-acetic acid methyl ester in Arabidopsis.
  Journal
Plant Cell Rep 27:575-84 (2008)
DOI:10.1007/s00299-007-0458-9
  Sequence
[ath:AT5G55250]
Reference
3  [PMID:18162595]
  Authors
Zhao N, Ferrer JL, Ross J, Guan J, Yang Y, Pichersky E, Noel JP, Chen F
  Title
Structural, biochemical, and phylogenetic analyses suggest that indole-3-acetic acid methyltransferase is an evolutionarily ancient member of the SABATH family.
  Journal
Plant Physiol 146:455-67 (2008)
DOI:10.1104/pp.107.110049
  Sequence
[osa:4337315]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.278
IUBMB Enzyme Nomenclature: 2.1.1.278
ExPASy - ENZYME nomenclature database: 2.1.1.278
BRENDA, the Enzyme Database: 2.1.1.278
LinkDB

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