KEGG ENZYME: 2.1.1.278

ENZYME: 2.1.1.278

Entry

EC 2.1.1.278                Enzyme

Name

indole-3-acetate O-methyltransferase;
IAA carboxylmethyltransferase;
IAMT

Class

Transferases;
Transferring one-carbon groups;
Methyltransferases

Sysname

S-adenosyl-L-methionine:(indol-3-yl)acetate O-methyltransferase

Reaction(IUBMB)

S-adenosyl-L-methionine + (indol-3-yl)acetate = S-adenosyl-L-homocysteine + methyl (indol-3-yl)acetate [RN:R10452]

Reaction(KEGG)

R10452

Substrate

S-adenosyl-L-methionine [CPD:C00019];
(indol-3-yl)acetate [CPD:C00954]

Product

S-adenosyl-L-homocysteine [CPD:C00021];
methyl (indol-3-yl)acetate [CPD:C20635]

Comment

Binds Mg2+. The enzyme is found in plants and is important for regulation of the plant hormone (indol-3-yl)acetate. The product, methyl (indol-3-yl)acetate is inactive as hormone [2].

History

EC 2.1.1.278 created 2013

Orthology

K18848

indole-3-acetate O-methyltransferase

Genes

ATH:	AT5G55250(IAMT1)

ALY:

9300463

CRB:

17876787

CSAT:

104726072 104731592 104761558 109127202

EUS:	EUTSA_v10015669mg

BRP:

103844968

BNA:	106429974 125579158

BOE:

106314016

RSZ:

108827575

THJ:	104811634 104817688

CPAP:

110820813

CIT:

102609472

CIC:	CICLE_v10008599mg

PVY:

116145152

MINC:

123192072 123201772 123202376

TCC:

18593419

GRA:

105781276

GHI:	107916882 107921728

GAB:

108481923

HSYR:

120126501 120145115 120160654 120202386

DZI:	111276433 111302246

EGR:	104448179 120294735

RARG:

115749976

GMX:	100801476 100805902 100807953

GSJ:	114384238 114395612 114402697 114424307

PVU:	137826667 137833064

VRA:	106764291 106774727

VAR:	108337490 108342409

VUN:	114187551 114193541

VUM:	124833035 124839492

CCAJ:

109806364 109811319

APRC:

113854354 113874579

MTR:	11425258 11435469 25489046

TPRA:

123916324 123918958 123920445

CAM:

101501068

PSAT:

127084846 127117629

VVO:	131617806 131646076 131656553

LJA:	130724074 130733064

ADU:	107473281 107496314

AIP:	107606437 107616468

AHF:	112701906 112720225 112767332 112790358

LANG:

109329113 109350940 109359499

PCIN:

129299852 129317740

QSA:	O6P43_013636 O6P43_021227

FVE:

101295605

AANS:

126787399

RCN:

112167364

PPER:

18779912 18780210 18780650 18787700

PMUM:

103326506 103326551 103326552 103333170

PAVI:

110752403 110752586 110766633 110766652 110766659 110768917

PDUL:

117619897 117624998 117625448 117626244

MDM:	103428134 103448357

MSYL:

126589708 126614480

PXB:	103927001 103951421

PCOX:

137714083 137741354

ZJU:

107434320

MNT:

21395657

CSAV:

115725140

CSV:

101213472

CMO:

103490122

BHJ:

120085398

MCHA:

111010498 111010558

CMAX:

111476788 111480601

CMOS:

111442937 111445917

CPEP:

111788985 111797338

RCU:

8268129

MEAN:

126669449

JCU:

105633024

HBR:	110646361 110670024

MESC:

110601438 110610534

POP:

7487519

PEU:

105141854

PALZ:

118056815

PNZ:

133681115

JRE:	108983414 108992349

CILL:

122281509 122289623

CAVE:

132175306

AGLU:

133876462

QSU:

112029893

QLO:

115955000

TWL:	119985165 119989971

VVI:

100258858

VRI:

117910005

SLY:	101263921 101268451

SPEN:

107005882 107024610

SOT:	102590393 102598710

SSTN:

125862547 125875655

SDUL:

129870858 129893445

CANN:

107877415

LBB:	132617894 132619253 132638544

NTA:	107814352 107819865 107821105 107832655

NSY:	104225348 104233292

NTO:	104088383 104121023

NAU:	109208188 109226709

INI:	109187364 109190737

ITR:	116011409 116022530

SIND:

105174912

OEU:	111376492 111395122

EGT:

105969193

SSPL:

121756544 121756867 121786407

SMIL:

130986240

SHIS:

125216281 125219683

APAN:

127247786

HAN:

110890061

ECAD:

122593380

LSV:

111898207

CCAV:

112508026

DCR:

108216756

CSIN:

114280095 114321588

RVL:

131329600

AEW:	130751150 130771556

DLT:

127791509

BVG:	104891752 104891754

SOE:

110777861

CQI:	110720881 110723927

ATRI:

130808095 130818297

MOF:

131164708

NNU:	104594143 104606532

MING:

122060482 122094202

TSS:	122640523 122641758

PSOM:

113285782 113333215

OSA:	107276275 4337315(IAMT1) 4340899

DOSA:

Os04g0665200 Os06g0322500 Os06g0323100

OBR:	102702090 102704052

OGL:	127771652 127777864

SVS:

117850524

PVIR:

120642779

PHAI:

112901107 112901210

PDA:

103702327

EGU:

105050524

MSIN:

131219580

ACAK:

137942747 137966548

NCOL:

116259088

ATR:

18429711

CJF:	131036490 131039096 131043095 131043098 131043099 131043102 131051820 131062579 131063649 131072274 131072275 131072277 131072278 131072279 131072280 131072281 131072282 131072284 131075528 131075538 131075539 131075541 131075542

MMAI:

sS8_3498

STAR:

G3545_19560

PHR:	C6569_06540

» show all

Reference

1 [PMID:12897246]

Authors

Zubieta C, Ross JR, Koscheski P, Yang Y, Pichersky E, Noel JP

Title

Structural basis for substrate recognition in the salicylic acid carboxyl methyltransferase family.

Journal

Plant Cell 15:1704-16 (2003)
DOI:10.1105/tpc.014548

Sequence

[ath:AT5G55250]

Reference

2 [PMID:17926040]

Authors

Li L, Hou X, Tsuge T, Ding M, Aoyama T, Oka A, Gu H, Zhao Y, Qu LJ

Title

The possible action mechanisms of indole-3-acetic acid methyl ester in Arabidopsis.

Journal

Plant Cell Rep 27:575-84 (2008)
DOI:10.1007/s00299-007-0458-9

Sequence

[ath:AT5G55250]

Reference

3 [PMID:18162595]

Authors

Zhao N, Ferrer JL, Ross J, Guan J, Yang Y, Pichersky E, Noel JP, Chen F

Title

Structural, biochemical, and phylogenetic analyses suggest that indole-3-acetic acid methyltransferase is an evolutionarily ancient member of the SABATH family.

Journal

Plant Physiol 146:455-67 (2008)
DOI:10.1104/pp.107.110049

Sequence

[osa:4337315]

Other DBs

ExplorEnz - The Enzyme Database:

2.1.1.278

IUBMB Enzyme Nomenclature:

2.1.1.278

ExPASy - ENZYME nomenclature database:

2.1.1.278

BRENDA, the Enzyme Database:

2.1.1.278

LinkDB

DBGET integrated database retrieval system