Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy

S-adenosyl-L-methionine:(R,S)-reticuline 7-O-methyltransferase

(1) S-adenosyl-L-methionine + (S)-reticuline = S-adenosyl-L-homocysteine + (S)-laudanine [RN:R10605];
(2) S-adenosyl-L-methionine + (R)-reticuline = S-adenosyl-L-homocysteine + (R)-laudanine [RN:R10606]

R10605 R10606;
(other) R08787 R08788
Reaction

S-adenosyl-L-methionine [CPD:C00019];
(S)-reticuline [CPD:C02105];
(R)-reticuline [CPD:C05178]

The enzyme from the plant Papaver somniferum (opium poppy) methylates (S)- and (R)-reticuline with equal efficiency and is involved in the biosynthesis of tetrahydrobenzylisoquinoline alkaloids.

EC 2.1.1.291 created 2013

1  [PMID:14675446]

Ounaroon A, Decker G, Schmidt J, Lottspeich F, Kutchan TM

(R,S)-Reticuline 7-O-methyltransferase and (R,S)-norcoclaurine 6-O-methyltransferase of Papaver somniferum - cDNA cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in opium poppy.

Plant J 36:808-19 (2003)
DOI:10.1046/j.1365-313X.2003.01928.x

[ag:AAQ01668]

2  [PMID:15353584]

Weid M, Ziegler J, Kutchan TM

The roles of latex and the vascular bundle in morphine biosynthesis in the opium  poppy, Papaver somniferum.

Proc Natl Acad Sci U S A 101:13957-62 (2004)
DOI:10.1073/pnas.0405704101

[ag:AAQ01668]