| Entry |
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| Name |
deoxycytidylate C-methyltransferase;
deoxycytidylate methyltransferase;
dCMP methyltransferase
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| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
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| Sysname |
5,10-methylenetetrahydrofolate:dCMP C-methyltransferase
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| Reaction(IUBMB) |
5,10-methylenetetrahydrofolate + dCMP = dihydrofolate + deoxy-5-methylcytidylate [RN: R01670]
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| Reaction(KEGG) |
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| Substrate |
5,10-methylenetetrahydrofolate [CPD: C00143];
dCMP [CPD: C00239]
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| Product |
dihydrofolate [CPD: C00415];
deoxy-5-methylcytidylate [CPD: C03495]
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| Comment |
dCMP is methylated by formaldehyde in the presence of tetrahydrofolate. CMP, dCTP and CTP can act as acceptors, but more slowly.
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| History |
EC 2.1.1.54 created 1978
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| Reference |
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| Authors |
Kuo TT, Tu J. |
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| Title |
Enzymatic synthesis of deoxy-5-methyl-cytidylic acid replacing deoxycytidylic acid in Xanthomonas oryzae phage Xp12DNA. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.1.1.54 |
| ExPASy - ENZYME nomenclature database: | 2.1.1.54 |
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| LinkDB |
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