KEGG   ENZYME: 2.3.1.158
Entry
EC 2.3.1.158                Enzyme                                 
Name
phospholipid:diacylglycerol acyltransferase;
PDAT
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
phospholipid:1,2-diacyl-sn-glycerol O-acyltransferase
Reaction(IUBMB)
phospholipid + 1,2-diacyl-sn-glycerol = lysophospholipid + triacylglycerol [RN:R05333]
Reaction(KEGG)
R05333
Substrate
phospholipid [CPD:C00865];
1,2-diacyl-sn-glycerol [CPD:C00641]
Product
lysophospholipid [CPD:C06254];
triacylglycerol [CPD:C00422]
Comment
This enzyme differs from EC 2.3.1.20, diacylglycerol O-acyltransferase, by synthesising triacylglycerol using an acyl-CoA-independent mechanism. The specificity of the enzyme for the acyl group in the phospholipid varies with species, e.g., the enzyme from castor bean (Ricinus communis) preferentially incorporates vernoloyl (12,13-epoxyoctadec-9-enoyl) groups into triacylglycerol, whereas that from the hawk's beard (Crepis palaestina) incorporates both ricinoleoyl (12-hydroxyoctadec-9-enoyl) and vernoloyl groups. The enzyme from the yeast Saccharomyces cerevisiae specifically transfers acyl groups from the sn-2 position of the phospholipid to diacylglycerol, thus forming an sn-1-lysophospholipid.
History
EC 2.3.1.158 created 2001
Pathway
ec00561  Glycerolipid metabolism
ec01100  Metabolic pathways
Orthology
K00679  phospholipid:diacylglycerol acyltransferase
Genes
ATH: AT3G44830 AT5G13640(PDAT)
ALY: 9309690 9313438
CRB: 17881928 17885438
CSAT: 104705618 104735371 104769582 104780334 104790735
EUS: EUTSA_v10002852mg EUTSA_v10012888mg
BRP: 103846553 103850885
BNA: 106372279 106377188 106406534 125579045
BOE: 106318490 106327439
RSZ: 108817295 108842067
THJ: 104799356 104809891 104814810
CPAP: 110808547 110817685 110818323
CIT: 102608065 102609133 102609799
CIC: CICLE_v10025070mg CICLE_v10025078mg CICLE_v10027727mg
PVY: 116120024 116142184 116146808
MINC: 123199205 123200792 123211318 123219550
TCC: 18588322 18590424 18596196
GRA: 105772831 105774265 105784202 105792333 105792937 105799046
GHI: 107891726 107897707 107901080 107932867 107941265 107944192 107947285 107949699 107953304 107954163 107960298 121204773
GAB: 108456991 108458391 108470153 108474009 108480395
HSYR: 120115067 120116364 120129627 120134614 120149808 120151224 120152562 120159321 120217305
DZI: 111274675 111279003 111286760 111299177 111303069 111303764
EGR: 104421248 104422999 104436439
RARG: 115735434 115737938 115740661
GMX: 100779225 100797438 100800857 100803760 100806313 100812643
GSJ: 114372974 114379317 114382442 114390510 114392747 114418155
PVU: 137807190 137810082 137819738
VRA: 106769440 106774144
VAR: 108319333 108338425
VUN: 114166844 114178533
VUM: 124823546 124846718 124846736
CCAJ: 109799093 109802310 109808306
APRC: 113846357 113849576 113860043
MTR: 25492334 25500534
TPRA: 123881556 123884317
CAM: 101497807 101499408 101505056
PSAT: 127076307 127105648
VVO: 131616401 131637879
LJA: 130710590 130742979 130746487
ADU: 107457657 107464761 107479082
AIP: 107618017 107634440 107643486
AHF: 112710451 112723677 112735910 112770407 112775717
LANG: 109334037 109347629 109355287 109356249
PCIN: 129288935 129309969 129315649 129321050
QSA: O6P43_022460 O6P43_027577 O6P43_028465
FVE: 101301468 101311410
AANS: 126787620 126799173
RCN: 112163750 112187750
PPER: 18771381 18774807
PMUM: 103326545 103340552
PAVI: 110749222 110755303
PDUL: 117631934 117634845
MDM: 103400853 103448013 103450792
MSYL: 126591442 126604143 126606472
PXB: 103929853 103932552 103951912
PCOX: 137740498 137743846 137747396
ZJU: 107403549 107410573 107424140
MNT: 21396621 21397235 21409968
CSAV: 115698889 115705212 115707043
CSV: 101215610 101222563
CMO: 103497986 103500706
BHJ: 120085798 120088742
MCHA: 111011365 111018295
CMAX: 111484072 111488585 111494451
CMOS: 111448684 111456080 111464287
CPEP: 111777293 111778524 111807354
RCU: 8266990 8272509 8284674
MEAN: 126669265 126681645
JCU: 105631411 105637340 105637933(PDAT)
HBR: 110632849 110635770 110641537 110651489 110668138
MESC: 110612221 110613312 110613532 110626552 110626764
POP: 18098005 7475706 7490955
PEU: 105111967 105118354 105133404 105136421
PALZ: 118034818 118038074 118045532 118060023
PNZ: 133672482 133698931 133700636
JRE: 108985608 109000668 109005305 109008819
CILL: 122292297 122300922 122304312 122307891
CAVE: 132163820 132165699 132187250
AGLU: 133857149 133862994 133878550
QSU: 111994356 112012906 112023522
QLO: 115976039 115976040 115989696
TWL: 119993493 120002366 120002391
VVI: 100243077 100256634 100259274
VRI: 117915678 117922549 117925314
SLY: 101258674 101259322 101261928 101263223 101266485
SPEN: 107004164 107014474 107021662 107022891 107024408
SOT: 102586946 102590232 102597079 102597924 102606040
SSTN: 125844671 125857978 125872487 125875158 125876187
SDUL: 129893309 129894181 129900758 129900946 129904573
CANN: 107848184 107861698 107874787 107875629 107877860
LBB: 132600511 132604477 132616596 132618405 132633501
NTA: 107768032 107775478 107782802 107789323 107809139 107811062 107815607 107818243
NSY: 104220307 104221715 104236791 104239807 104240673
NTO: 104090483 104097532 104116567 104121161
NAU: 109211607 109214649 109217286 109218871 109242616
INI: 109186432 109187504 109193143
ITR: 116009903 116013955 116014715
SIND: 105157789 105163255 105169966 105173654
OEU: 111401505 111401783
EGT: 105951305 105958532 105971047 105975942
SSPL: 121744432 121745022 121767668 121790702 121794181 121797749 121811371 121811380
SMIL: 130987153 130990776 131013127 131020277
SHIS: 125186420 125205938 125208495 125210556
APAN: 127239341 127243274 127251857 127262807
HAN: 110886458 110893689 110904203 110909071 118490100
ECAD: 122595117 122595250 122603264 122607890
LSV: 111892640 111899140 111901442 111905326 111910335
CCAV: 112500771 112511716 112516913 112516986 112522263
DCR: 108192584 108206149 108213502 108223304 108227780
CSIN: 114270756 114276665 114291097 114296637
RVL: 131310725 131313469 131320048
AEW: 130770873 130782761 130784598
DLT: 127795709
BVG: 104883605 104899770
SOE: 110793733 110803768
CQI: 110683011 110684360 110688112 110715985
ATRI: 130813735 130824408
MOF: 131149791 131158209 131164485
NNU: 104600613 104609357 104612529
MING: 122064870 122086945
TSS: 122656175 122667478
PSOM: 113314070 113321076 113347605 113350354 113351133 113352849
OSA: 4347190
DOSA: Os09g0444200
OBR: 102703714
OGL: 127784638
BDI: 100835274
ATS: 109745768
TDC: 119301544 119309383
TAES: 123103717 123111938 123121495
TUA: 125509275
LPER: 127301758
LRD: 124658202
SBI: 8081010
ZMA: 100191489 100273525
MFLO: 136541993
SITA: 101769545
SVS: 117843960
PVIR: 120660811 120680373
PHAI: 112880526
PAUA: 133901737
PDA: 103708654
EGU: 105041806
MUS: 103977610 103998045
ZOF: 122026964 122029496 122032825 122033498
DCT: 110096119
PEQ: 110022551
AOF: 109823033 109844472
MSIN: 131235112 131251683
ACAK: 137956206 137958370 137960122
NCOL: 116262343
ATR: 18439382 18441499
CJF: 131048539 131069543
SMO: SELMODRAFT_164869 SELMODRAFT_171888
PPP: 112275614
CRE: CHLRE_02g106400v5
VCN: VOLCADRAFT_97885
MNG: MNEG_3131
CSL: COCSUDRAFT_37169
OLU: OSTLU_1469
OTA: OT_ostta09g03210
BPG: Bathy10g01290
MIS: MICPUN_58725
MPP: MICPUCDRAFT_58904
SCE: YNR008W(LRO1)
SEUB: DI49_4743
SPAO: SPAR_N03100
AGO: AGOS_AFL179C
ERC: Ecym_2120
KLA: KLLA0_F06380g
KMX: KLMA_60455(LRO1)
LTH: KLTH0A05742g
ZRO: ZYRO0C05478g
CGR: 2889345(GVI51_I05555)
NCS: NCAS_0G00980(NCAS0G00980)
NDI: NDAI_0F01110(NDAI0F01110)
TPF: TPHA_0D03660(TPHA0D03660)
TBL: TBLA_0A02430(TBLA0A02430)
TGB: HG536_0A08690
TDL: TDEL_0A07120(TDEL0A07120)
KAF: KAFR_0F00910(KAFR0F00910)
KNG: KNAG_0D00600(KNAG0D00600)
ZMK: HG535_0A06970
SLUD: SCDLUD_001195
DHA: DEHA2D09922g
PIC: PICST_72946(LRO1)
PGU: PGUG_04692
SPAA: SPAPADRAFT_132946
LEL: PVL30_001349(LRO1)
LBG: 92208224(LODBEIA_P30280)
CAL: CAALFM_C100870WA(LRO1)
CTP: CTRG_04390
COT: CORT_0B11180
CDU: CD36_00820
CTEN: 18250155(LRO1)
CLU: CLUG_00975
CLUS: A9F13_09g00253
CAUR: CJI96_0003728
ASAU: 88173956(PUMCH_002892)
PPA: PAS_chr2-1_0878
PKZ: C5L36_0A12660
BNN: FOA43_000117
BBRX: BRETT_000982
OPA: HPODL_01811
YLI: 2911637(YALI2_E01425g)
SLB: AWJ20_3581(LRO1)
NCR: NCU02416
NTE: NEUTE1DRAFT85933(NEUTE1DRAFT_85933)
SMP: 10801649(SMAC4_08306)
PAN: PODANSg9241
PBEL: QC761_505600(LRO1)
PPSD: QC762_505600(LRO1)
PPSP: QC763_505600(LRO1)
PPSA: QC764_505600(LRO1)
TTT: THITE_2116760
MTM: MYCTH_2309146
CTHR: CTHT_0048370
RTHE: 98123956(VTJ83DRAFT_2982)
MGR: MGG_03560
PPEI: PpBr36_06697
PGRI: PgNI_00461
TMN: UCRPA7_1931
SSCK: SPSK_00461
FGR: FGSG_06375
FPU: FPSE_12276
FPOA: FPOAC1_009372
FVN: FVRRES_10008
FVR: FVEG_05051
FOX: FOXG_08128
NHE: NECHADRAFT_59755
FFC: NCS54_00514400
FKR: NCS57_00552500
FMU: J7337_007087
TRE: TRIREDRAFT_121546
TRR: M419DRAFT_98582
TATV: 25778535(TrAtP1_008087)
TASP: 36617887(TrAFT101_003276)
MAW: 19249027(LRO1)
MAJ: MAA_04510
MBRN: 26240179(plh1)
PCHM: VFPPC_17845
CMT: CCM_01242
AMUS: LMH87_005827
PLJ: 28884397(PLICBS_005658)
PTKZ: JDV02_003712(LRO1)
VAL: VDBG_09717
VDA: VDAG_09453
CFJ: CFIO01_08076
CLUP: CLUP02_06211
CHIG: CH63R_01158
CDET: 87939901(CDEST_03398)
SAPO: SAPIO_CDS4514
ELA: UCREL1_3852
PFY: PFICI_03524
SSL: SS1G_11136
BFU: BCIN_02g05210(Bclro1)
MBE: MBM_06753
PSCO: LY89DRAFT_686481
GLZ: GLAREA_10021
ANI: ANIA_04992
AFM: AFUA_3G09950
ACT: ACLA_037790
NFI: NFIA_067340
AOR: AO090003000514
ANG: An16g03640
AFV: AFLA_001177
ALUC: AKAW2_70312S
ACHE: ACHE_20944S
APUU: APUU_30836S
PCS: N7525_001059
PDP: PDIP_76480
POU: POX_b03253
TMF: EYB26_001046
TRG: TRUGW13939_03288
CIM: CIMG_03952
CPW: 9693864(D8B26_003408)
URE: UREG_01995
ABE: ARB_01216
TVE: TRV_01292
PBL: PAAG_07904
PBN: PADG_08171
AJE: HCAG_05471
BGH: BDBG_02489
PNO: SNOG_03081
PTE: PTT_20057
PTRR: 6339570(PtrM4_025410)
BZE: COCCADRAFT_33431
BSC: COCSADRAFT_158418
BOR: COCMIDRAFT_83639
AALT: CC77DRAFT_947980
ADAC: 96087771(ACET3X_007449)
ARAB: EKO05_0000339
ZTR: MYCGRDRAFT_73528
PFJ: MYCFIDRAFT_155012
FFU: CLAFUR5_09068
CBET: CB0940_10472
BCOM: BAUCODRAFT_109446
NPA: UCRNP2_3325
TML: GSTUM_00000255001
SPO: 2541187(plh1)
SOM: SOMG_01018(plh1)
CNE: CNL04710
CNB: CNBI2140
CNG: CNAG_05152
CGI: CGB_D2350W
CDEU: CNBG_4542
CDEP: 91090509(L203_106301)
KMG: 30163887(I203_103832)
KNE: 92179119(IAR55_001860)
TMS: TREMEDRAFT_68093
TASA: A1Q1_06453
CCAC: CcaHIS019_0701660(LRO1)
TVS: TRAVEDRAFT_56169
DSQ: DICSQDRAFT_132754
PCO: PHACADRAFT_197922
SHS: STEHIDRAFT_60411
HIR: HETIRDRAFT_57041
PSQ: PUNSTDRAFT_105867
ADL: AURDEDRAFT_113617
FME: FOMMEDRAFT_16796
GTR: GLOTRDRAFT_135908
RSX: RhiXN_07200
LBC: LACBIDRAFT_156742(PDAT)
CCI: CC1G_02002
ABP: AGABI1DRAFT71227(AGABI1DRAFT_71227)
ABV: AGABI2DRAFT204119(AGABI2DRAFT_204119)
PCUB: JR316_0002060
MRR: Moror_1504
SCM: SCHCO_02631503(SCHCODRAFT_02631503)
CPUT: CONPUDRAFT_57356
SLA: SERLADRAFT_447691
WSE: WALSEDRAFT_59615
WIC: J056_003834
UMA: UMAG_00322
PFP: PFL1_03662
SGRA: EX895_000548
MGL: MGL_3157
MRT: MRET_2127
MSYM: MSY001_2834
PGR: PGTG_14693
PTRC: PtA15_4A107
PSTR: Pst134EA_011137
MLR: MELLADRAFT_88797
RIE: OCT59_024851
EHI: EHI_099180(57.t00020)
ACAN: ACA1_074840 ACA1_327920 ACA1_399790
PTI: PHATRDRAFT_8860
FCY: FRACYDRAFT_166543
TPS: THAPSDRAFT_261132(PDT1)
AAF: AURANDRAFT_1287 AURANDRAFT_23177
PIF: PITG_11965
PSOJ: PHYSODRAFT_355873
TBR: Tb11.01.4790
TBG: TbgDal_XI14750
TCR: 506757.10 510359.340
LMA: LMJF_09_1040
LIF: LINJ_09_1100
LDO: LDBPK_091100
LMI: LMXM_09_1040
LMAT: 92517503(LSCM1_07627)
LBZ: LBRM_09_1100
LPAN: LPMP_091050
LOI: 92362644(LSCM4_06798)
LEIS: 94182546(GH5_07289)
LENR: 94174396(CUR178_07237)
LEIN: 94190499(JIQ42_06899)
PHET: 94292965(JKF63_06941)
GTT: GUITHDRAFT_159571
 » show all
Reference
1  [PMID:10829075]
  Authors
Dahlqvist A, Stahl U, Lenman M, Banas A, Lee M, Sandager L, Ronne H, Stymne S
  Title
Phospholipid:diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants.
  Journal
Proc Natl Acad Sci U S A 97:6487-92 (2000)
DOI:10.1073/pnas.120067297
  Sequence
[sce:YNR008W]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.158
IUBMB Enzyme Nomenclature: 2.3.1.158
ExPASy - ENZYME nomenclature database: 2.3.1.158
BRENDA, the Enzyme Database: 2.3.1.158
CAS: 288587-47-3
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