KEGG   ENZYME: 2.3.1.192
Entry
EC 2.3.1.192                Enzyme                                 
Name
glycine N-phenylacetyltransferase;
arylacetyl-CoA N-acyltransferase;
arylacetyltransferase;
GAT (gene name)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
phenylacetyl-CoA:glycine N-phenylacetyltransferase
Reaction(IUBMB)
phenylacetyl-CoA + glycine = CoA + phenylacetylglycine [RN:R05841]
Reaction(KEGG)
R05841
Substrate
phenylacetyl-CoA [CPD:C00582];
glycine [CPD:C00037]
Product
CoA [CPD:C00010];
phenylacetylglycine [CPD:C05598]
Comment
Not identical with EC 2.3.1.13 (glycine N-acyltransferase).
This enzyme was purified from bovine liver mitochondria. L-asparagine, L-glutamine and L-arginine are alternative substrates to glycine, but have higher Km values.
History
EC 2.3.1.192 created 2010
Pathway
ec00360  Phenylalanine metabolism
Orthology
K15517  glycine N-phenylacetyltransferase
Genes
CSYR103269913
MMUR105863142
OGA100958872
MMU240549(Gm4952)
MCAL110285808
MPAH110334998
RNO309227(Glyatl1)
MCOC116101065
MUN110565451
CGE100767729
MAUA101831264
PLEU114703388
MORG121454180
NGI103733339
HGL101711041
CPOC100723240 100723515 100723793 100725009
CCAN109678085
DORD105995256
DSP122105365
NCAR124958706 124958708
OCU100353150
OPI101520259
TUP102491601
CFA483462
VVP112930486
VLG121472025
UMR103666138
UAH113246550
UAR123785073
ELK111149994
LLV125078916
MPUF101672241
ORO101370540
EJU114215402
ZCA113915067
MLX118016301
FCA101098257
PYU121043387
PBG122483803
PTG102966488
PPAD109246473
AJU113592388
HHV120240386
BTA112441481 280801(GAT)
BOM102284675
BIU109569853
BBUB123329683 123464552
CHX102175783
OAS101108949
ODA120877112
CCAD122449390 122449921
SSC100517803
CFR102512072
CBAI105070058
CDK105094919
VPC102544185
BACU103014180
LVE103084684
OOR101287278
DLE111183923
PCAD102988322
PSIU116758228
ECB100068389
EPZ103556887
EAI106825140
MYB102251191
MYD102768664
MMYO118664989
MLF102438929
PKL118712811
DRO112303569
SHON118996869(GLYAT)
AJM119058880(GLYAT)
PDIC114500945
PHAS123829309
MMF118628379 118628415
MJV108407616
TOD119255257
SARA101552414
DNM101422296 101423464
GAS123252717
PMAX117339082
 » show all
Reference
1  [PMID:457678]
  Authors
Nandi DL, Lucas SV, Webster LT Jr
  Title
Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization.
  Journal
J Biol Chem 254:7230-7 (1979)
Reference
2  [PMID:2283662]
  Authors
Kelley M, Vessey DA
  Title
The effects of ions on the conjugation of xenobiotics by the aralkyl-CoA and arylacetyl-CoA N-acyltransferases from bovine liver mitochondria.
  Journal
J Biochem Toxicol 5:125-35 (1990)
DOI:10.1002/jbt.2570050208
Reference
3  [PMID:9664233]
  Authors
Vessey DA, Lau E
  Title
Determination of the sequence of the arylacetyl acyl-CoA:amino acid N-acyltransferase from bovine liver mitochondria and its homology to the aralkyl acyl-CoA:amino acid N-acyltransferase.
  Journal
J Biochem Mol Toxicol 12:275-9 (1998)
DOI:10.1002/(SICI)1099-0461(1998)12:5<275::AID-JBT3>3.0.CO;2-I
  Sequence
[bta:280801]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.192
IUBMB Enzyme Nomenclature: 2.3.1.192
ExPASy - ENZYME nomenclature database: 2.3.1.192
BRENDA, the Enzyme Database: 2.3.1.192
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