KEGG   ENZYME: 2.3.1.209
Entry
EC 2.3.1.209                Enzyme                                 
Name
dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase;
VioB
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
acetyl-CoA:dTDP-4-amino-4,6-dideoxy-alpha-D-glucose N-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose = CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose [RN:R10174]
Reaction(KEGG)
R10174
Substrate
acetyl-CoA [CPD:C00024];
dTDP-4-amino-4,6-dideoxy-alpha-D-glucose [CPD:C04268]
Product
CoA [CPD:C00010];
dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose [CPD:C06018]
Comment
The non-activated product, 4-acetamido-4,6-dideoxy-alpha-D-glucose, is part of the O antigens of Shigella dysenteriae type 7 and Escherichia coli O7.
History
EC 2.3.1.209 created 2012
Pathway
ec00541  O-Antigen nucleotide sugar biosynthesis
ec01100  Metabolic pathways
Orthology
K21379  dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase
Genes
ECTECIAI39_0980(vioB)
EBRECB_01941(vioB)
EBLECD_01941(vioB)
EBEB21_01930(ybl96)
EBDECBD_1620
SHQA0259_14010
ESHC1N69_14920
ATGJ4G44_00255
SHEShewmr4_1322
SHWSputw3181_1469
FSRKQR59_07415
AHIVU14_07305
 » show all
Reference
1  [PMID:17905981]
  Authors
Wang Y, Xu Y, Perepelov AV, Qi Y, Knirel YA, Wang L, Feng L
  Title
Biochemical characterization of dTDP-D-Qui4N and dTDP-D-Qui4NAc biosynthetic pathways in Shigella dysenteriae type 7 and Escherichia coli O7.
  Journal
J Bacteriol 189:8626-35 (2007)
DOI:10.1128/JB.00777-07
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.209
IUBMB Enzyme Nomenclature: 2.3.1.209
ExPASy - ENZYME nomenclature database: 2.3.1.209
BRENDA, the Enzyme Database: 2.3.1.209
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